
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Systematic discovery of Xist RNA binding proteins - PMC
Description:
Noncoding RNAs (ncRNAs) function with associated proteins to effect complex structural and regulatory outcomes. To reveal the composition and dynamics of specific noncoding RNA- protein complexes (RNPs) in vivo, we developed comprehensive ...
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Keywords {π}
xist, doi, proteins, figure, rna, google, scholar, pubmed, silencing, chirpms, cells, cell, pmc, article, free, xci, hnrnpk, spen, protein, gene, arepeat, chromosome, prc, binding, set, nature, retrieved, interaction, enriched, control, differentiation, depletion, chromatin, factors, complex, interactions, rnf, inactivation, histone, required, expression, nuclear, results, hnrnpu, pdf, interactors, stem, wutz, chirp, performed,
Topics {βοΈ}
bis-tris sds-page gels biotinylated anti-sense oligos pmc beta search [google scholar] gillich retinoic acid-induced differentiation mbd3-nurd complex nominates initial xist-induced targeting pathogen rna-protein interactomes undergone ra-induced differentiation ectopic xist rnaβcoating rna-binding kh domains extra-embryonic trophectoderm cells physiological rna-protein interactions conserved a-repeat element a-repeat mutant knocked nurd subunits reveals x-linked gene pgk1 protein-rna interaction network performing xist chirp-ms a-repeat associating factors potential step-wise assembly xist-mediated chromatin modifications imprinted grb10/meg1 gene sin3-hdac1 components spen u2 chirp-ms reveal lc/ms-ms identification performed parallel chirp-ms evaluate xist-specific interactions xist a-repeat mutant prc1-dependent recruitment a-repeat deletion highlights human x-inactivation centre uv-crosslinking rnp immunoprecipitation xist-mediated gene silencing a-repeat binding factors early post-implantation development compared xist chirp-ms xist-recruited silencing activities describe rna-protein interaction intricate epigenetic system lncrna-mediated gene regulation supplementary materials included xist a-repeat region control protein beta-actin u2-enriched rna sizes u2-binding protein u2b chromatin modifying functions x-linked genes rnf12 x-linked genes mecp2 xist chirp-ms rank
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