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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. Social Networks
  10. External Links
  11. Analytics And Tracking
  12. Libraries
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  14. CDN Services

We began analyzing https://ehoonline.biomedcentral.com/articles/10.1186/s40164-025-00676-x, but it redirected us to https://ehoonline.biomedcentral.com/articles/10.1186/s40164-025-00676-x. The analysis below is for the second page.

Title[redir]:
Platelets in cancer and immunotherapy: functional dynamics and therapeutic opportunities | Experimental Hematology & Oncology | Full Text
Description:
Platelets play a critical role in tumor immunity, particularly in promoting cancer progression. Numerous studies suggest that platelets could serve as a novel target for cancer immunotherapy, however, no comprehensive reviews have yet summarized and discussed this potential. Our review provides an in-depth discussion of the roles and mechanisms of platelets within both the immunosuppressive tumor microenvironment and the anti-tumor immune microenvironment. Additionally, we summarize the key therapeutic targets and approaches for clinical translation. This work offers essential insights for reprogramming platelets to shift their function from tumor promotion to tumor suppression, providing a foundation for the development of novel immunotherapeutic strategies and related research.

Matching Content Categories {📚}

  • Science
  • Health & Fitness
  • Education

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🚄 Respectable Traffic: 10k - 20k visitors per month


Based on our best estimate, this website will receive around 10,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {💸}

We don’t know how the website earns money.

Many websites are intended to earn money, but some serve to share ideas or build connections. Websites exist for all kinds of purposes. This might be one of them. Doi.org has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

pubmed, platelets, cancer, article, google, scholar, tumor, cas, cells, cell, platelet, central, immune, immunotherapy, tgfβ, patients, plateletderived, growth, immunity, activation, wang, clinical, therapy, antitumor, inhibition, immunosuppressive, zhang, metastasis, pdl, liu, sci, efficacy, lung, blood, chen, role, progression, microenvironment, tumors, factor, signaling, nat, targeting, metastatic, natural, antibodies, res, therapeutic, potential, delivery,

Topics {✒️}

bifunctional anti-pd-l1/tgf-βrii agent anti-pd-l1 checkpoint antibody platelet-derived pdgf-dd supports pd-1/pd-l1 immune checkpoints anti-pd-l1 antibodies home stat3/nf-κb signaling activation overactive garp-tgf-β signaling platelet-derived tgf-β1 mediates stromal cell-derived tgf-β small-molecule tgf-β receptor tgf-β/nkg2d axis represents tumor-intrinsic cox-associating signaling facilitating car-t-cell infiltration targeting platelet-derived tgf-β transforming growth factor-β anti-pd-l1 antibodies tumor-specific t-cells engineered nf-κb activators drive platelet-derived growth factor low-molecular-weight heparin tgf-β signaling pathway cd8⁺ t-cell infiltration platelet pd-l1 acquired anti-pd-1 antibodies traffic promoting pd-l1 expression pm-coated anti-cancer drugs platelet-derived tgf-β including pm-conjugated nanodrugs supplementing t-cell cultures anti-pd-l1 therapy [126] platelet-derived mhc class cd8⁺ t-cell function enhance t-cell responses restore anti-tumor immunity platelet membrane-coated nanoparticles face detachment-induced apoptosis anti-pd-l1 immunotherapy hmgb1/lrrc32 signaling axis tumor growth factor-β myeloid-derived suppressor cell cell-mediated antitumor immunity platelet-derived small evs latent tgf-β1 presentation castration-resistant prostate cancer cell-recruiting bispecific antibodies platelet-induced hemangioendothelioma growth anchors latent tgf-β monocyte-platelet interaction induces cell-mediated immune response enhances anti-tumor immunity

Schema {🗺️}

WebPage:
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         headline:Platelets in cancer and immunotherapy: functional dynamics and therapeutic opportunities
         description:Platelets play a critical role in tumor immunity, particularly in promoting cancer progression. Numerous studies suggest that platelets could serve as a novel target for cancer immunotherapy, however, no comprehensive reviews have yet summarized and discussed this potential. Our review provides an in-depth discussion of the roles and mechanisms of platelets within both the immunosuppressive tumor microenvironment and the anti-tumor immune microenvironment. Additionally, we summarize the key therapeutic targets and approaches for clinical translation. This work offers essential insights for reprogramming platelets to shift their function from tumor promotion to tumor suppression, providing a foundation for the development of novel immunotherapeutic strategies and related research.
         datePublished:2025-06-13T00:00:00Z
         dateModified:2025-06-13T00:00:00Z
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                        type:PostalAddress
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                        type:PostalAddress
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                        type:PostalAddress
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                        type:PostalAddress
                     type:Organization
                     name:Central South University
                     address:
                        name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
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      context:https://schema.org
ScholarlyArticle:
      headline:Platelets in cancer and immunotherapy: functional dynamics and therapeutic opportunities
      description:Platelets play a critical role in tumor immunity, particularly in promoting cancer progression. Numerous studies suggest that platelets could serve as a novel target for cancer immunotherapy, however, no comprehensive reviews have yet summarized and discussed this potential. Our review provides an in-depth discussion of the roles and mechanisms of platelets within both the immunosuppressive tumor microenvironment and the anti-tumor immune microenvironment. Additionally, we summarize the key therapeutic targets and approaches for clinical translation. This work offers essential insights for reprogramming platelets to shift their function from tumor promotion to tumor suppression, providing a foundation for the development of novel immunotherapeutic strategies and related research.
      datePublished:2025-06-13T00:00:00Z
      dateModified:2025-06-13T00:00:00Z
      pageStart:1
      pageEnd:17
      license:http://creativecommons.org/publicdomain/zero/1.0/
      sameAs:https://doi.org/10.1186/s40164-025-00676-x
      keywords:
         Cancer
         Platelet
         Tumor microenvironment
         Immunotherapy
         Hematology
         Oncology
         Cancer Research
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         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs40164-025-00676-x/MediaObjects/40164_2025_676_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs40164-025-00676-x/MediaObjects/40164_2025_676_Fig3_HTML.png
      isPartOf:
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         name:BioMed Central
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            name:Changjing Cai
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                     type:PostalAddress
                  type:Organization
                  name:Central South University
                  address:
                     name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Yiting Liu
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                  name:Central South University
                  address:
                     name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
                  name:Central South University
                  address:
                     name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ruohuang Lu
            affiliation:
                  name:Central South University
                  address:
                     name:Department of Stomatology, the Third Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Xudong Fan
            affiliation:
                  name:Central South University
                  address:
                     name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
                  name:Central South University
                  address:
                     name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Shan Zeng
            affiliation:
                  name:Central South University
                  address:
                     name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
                  name:Central South University
                  address:
                     name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Pingping Gan
            affiliation:
                  name:Central South University
                  address:
                     name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
                     type:PostalAddress
                  type:Organization
                  name:Central South University
                  address:
                     name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
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         type:PostalAddress
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         name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
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      address:
         name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
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         type:PostalAddress
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      address:
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         type:PostalAddress
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      address:
         name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
      name:Central South University
      address:
         name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
      name:Central South University
      address:
         name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
      name:Central South University
      address:
         name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
      name:Central South University
      address:
         name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
         type:PostalAddress
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      address:
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            address:
               name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
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            address:
               name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
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      name:Yiting Liu
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            address:
               name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
            name:Central South University
            address:
               name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
      name:Ruohuang Lu
      affiliation:
            name:Central South University
            address:
               name:Department of Stomatology, the Third Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
      name:Xudong Fan
      affiliation:
            name:Central South University
            address:
               name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
            name:Central South University
            address:
               name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
      name:Shan Zeng
      affiliation:
            name:Central South University
            address:
               name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
            name:Central South University
            address:
               name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
      name:Pingping Gan
      affiliation:
            name:Central South University
            address:
               name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
            name:Central South University
            address:
               name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
      name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
      name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
      name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
      name:Department of Stomatology, the Third Xiangya Hospital, Central South University, Changsha, China
      name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
      name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
      name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
      name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China
      name:Department of Oncology, Xiangya Hospital, Central South University, Changsha, China
      name:National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

Social Networks {👍}(2)

External Links {🔗}(924)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Particles.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

5.6s.