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🌠 Phenomenal Traffic: 5M - 10M visitors per month


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Keywords {🔍}

doi, scholar, pubmed, google, tgfβ, cell, cells, emt, pmc, article, free, cancer, epithelial, rreb, smad, emts, signaling, biol, expression, genes, transition, tumor, epithelialmesenchymal, differentiation, transcription, wound, factors, induction, fibrosis, metastasis, ras, activation, induces, massagué, snail, mouse, dev, development, tissue, pathways, growth, nodal, gene, factor, pancreatic, smads, fibrogenic, healing, gastrulation, transcriptional,

Topics {✒️}

phosphoinositide 3-kinase-akt-mammalian target tgfβriii-p38mapk-ps249/t252rb pathway ccaat/enhancer-binding protein-α transforming growth factor-beta transforming growth factor-beta1 transforming growth factor-β tgf-β-induced emt plays tgf-beta1/smad3 signaling protects decoupling tgf-β-induced emt tgf-beta induced transdifferentiation snail1-induced partial epithelial tgf-β receptor complex cyclin-dependent kinase inhibitor pmc beta search tgf-β-smad signaling pathway nodal/activin receptor complex tgf-β-induced emt coupled ras-dependent transcription factor benign breast-biopsy specimens foxh1-occupied cis-elements tgf-β induced dormancy signal-driven transcription factors tgf-β controls dormancy tgf-β-induced production cyclin-dependent kinase inhibitors cognate sites genome-wide tgf-β gene responses wild-type mouse blastocysts antagonizing p53-mediated apoptosis context-dependent dna-binding cofactors tgf-beta-stimulated cooperation myocardin-related transcription factors lineage-determining transcription factors single-cell transcriptomic analysis sequential elevation h-ras tgf-β promotes heterogeneity tgf-β family members genome-wide binding partner brown fat-specific genes tgf-beta1-induced emt nodal-activated smad3 cooperates tgf-β induces snail tgf-β orchestrates fibrogenic tgf-β-induced emt tgf-β induced emt elicit epithelial-mesenchymal transition premature epithelial-mesenchymal transition regulate snail1 expression pre-malignant pancreatic progenitors tgf-β-induced emts

Questions {❓}

• If TGF-β signaling drives EMT together with fibrogenesis or differentiation in a context-dependent fashion, might the activation of EMT be directly and specifically coupled with the activation of these accompanying programs and an essential feature of the developmental or regenerative processes?
• If the main function of RREB1 is not recruiting SMADs to target genes (FOXH1 serves this function in mesendoderm progenitors [32,98]), what biochemical functions then does RREB1 bring to its collaboration with SMADs in the transcriptional activation of these genes?
• In the context of fibrosis, if TGF-β is a direct and potent activator of stromal fibroblasts, what is the role of the TGF-β-induced production of fibrogenic factors by epithelial cells undergoing EMT?

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• https://www.linkedin.com/company/ncbinlm
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• How much does https://scholar.google.com/scholar_lookup?journal=Genes%20Dev&title=TGF-beta-stimulated%20cooperation%20of%20smad%20proteins%20with%20the%20coactivators%20CBP/p300&author=R%20Janknecht&author=NJ%20Wells&author=T%20Hunter&volume=12&issue=14&publication_year=1998&pages=2114-2119&pmid=9679056&doi=10.1101/gad.12.14.2114& make?
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• https://doi.org/10.1172/JCI19270 income
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• Revenue of https://doi.org/10.1101/gad.10.19.2462
• What's the revenue for https://scholar.google.com/scholar_lookup?journal=Genes%20Dev&title=TGF-beta1%20and%20Ras%20collaborate%20in%20modulating%20the%20phenotypic%20plasticity%20and%20invasiveness%20of%20epithelial%20tumor%20cells&author=M%20Oft&author=J%20Peli&author=C%20Rudaz&author=H%20Schwarz&author=H%20Beug&volume=10&issue=19&publication_year=1996&pages=2462-2477&pmid=8843198&doi=10.1101/gad.10.19.2462&?
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• What's the monthly income of https://doi.org/10.1101/gad.181700?
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• See how much https://doi.org/10.1083/jcb.200109037 makes per month
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• Check the income stats for https://doi.org/10.1093/carcin/bgi043
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• How much income does https://doi.org/10.1074/jbc.M804777200 have?
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• https://doi.org/10.1083/jcb.122.1.103 income
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• What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Nature&title=A%20structural%20basis%20for%20mutational%20inactivation%20of%20the%20tumour%20suppressor%20Smad4&author=Y%20Shi&author=A%20Hata&author=RS%20Lo&author=J%20Massagu%C3%A9&author=NP%20Pavletich&volume=388&issue=6637&publication_year=1997&pages=87-93&pmid=9214508&doi=10.1038/40431&?
• What is the monthly revenue of https://doi.org/10.1126/science.7761852?
• What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Science&title=Inactivation%20of%20the%20type%20II%20TGF-beta%20receptor%20in%20colon%20cancer%20cells%20with%20microsatellite%20instability&author=S%20Markowitz&author=J%20Wang&author=L%20Myeroff&author=R%20Parsons&author=L%20Sun&volume=268&issue=5215&publication_year=1995&pages=1336-1338&pmid=7761852&doi=10.1126/science.7761852&?
• What are the total earnings of https://doi.org/10.1016/0092-8674(94)90572-x?
• How much cash flow does https://scholar.google.com/scholar_lookup?journal=Cell&title=Cloning%20of%20p27Kip1,%20a%20cyclin-dependent%20kinase%20inhibitor%20and%20a%20potential%20mediator%20of%20extracellular%20antimitogenic%20signals&author=K%20Polyak&author=MH%20Lee&author=H%20Erdjument-Bromage&author=A%20Koff&author=JM%20Roberts&volume=78&issue=1&publication_year=1994&pages=59-66&pmid=8033212&doi=10.1016/0092-8674(94)90572-x& have monthly?
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• How much revenue does https://scholar.google.com/scholar_lookup?journal=Genes%20Dev&title=Kip/Cip%20and%20Ink4%20Cdk%20inhibitors%20cooperate%20to%20induce%20cell%20cycle%20arrest%20in%20response%20to%20TGF-beta&author=I%20Reynisd%C3%B3ttir&author=K%20Polyak&author=A%20Iavarone&author=J%20Massagu%C3%A9&volume=9&issue=15&publication_year=1995&pages=1831-1845&pmid=7649471&doi=10.1101/gad.9.15.1831& generate?
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• https://scholar.google.com/scholar_lookup?journal=Nature&title=p15INK4B%20is%20a%20potential%20effector%20of%20TGF-beta-induced%20cell%20cycle%20arrest&author=GJ%20Hannon&author=D%20Beach&volume=371&issue=6494&publication_year=1994&pages=257-261&pmid=8078588&doi=10.1038/371257a0& income
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• How much does https://doi.org/10.1084/jem.20181827 earn?
• Profit of https://scholar.google.com/scholar_lookup?journal=J.%20Exp.%20Med&title=Context-dependent%20EMT%20programs%20in%20cancer%20metastasis&author=NM%20Aiello&author=Y%20Kang&volume=216&issue=5&publication_year=2019&pages=1016-1026&pmid=30975895&doi=10.1084/jem.20181827&
• https://doi.org/10.1016/j.cell.2009.11.007 income
• What's the financial gain of https://scholar.google.com/scholar_lookup?journal=Cell&title=Epithelial-mesenchymal%20transitions%20in%20development%20and%20disease&author=JP%20Thiery&author=H%20Acloque&author=RY%20Huang&author=MA%20Nieto&volume=139&issue=5&publication_year=2009&pages=871-890&pmid=19945376&doi=10.1016/j.cell.2009.11.007&?
• Check the income stats for https://doi.org/10.1016/j.cell.2014.07.013
• How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Circulating%20tumor%20cell%20clusters%20are%20oligoclonal%20precursors%20of%20breast%20cancer%20metastasis&author=N%20Aceto&author=A%20Bardia&author=DT%20Miyamoto&author=MC%20Donaldson&author=BS%20Wittner&volume=158&issue=5&publication_year=2014&pages=1110-1122&pmid=25171411&doi=10.1016/j.cell.2014.07.013& gross monthly?
• How much does https://doi.org/10.1016/j.trecan.2015.07.006 pull in?
• What's the financial intake of https://scholar.google.com/scholar_lookup?journal=Trends%20Cancer&title=En%20route%20to%20metastasis:%20circulating%20tumor%20cell%20clusters%20and%20epithelial-to-mesenchymal%20transition&author=N%20Aceto&author=M%20Toner&author=S%20Maheswaran&author=DA%20Haber&volume=1&issue=1&publication_year=2015&pages=44-52&pmid=28741562&doi=10.1016/j.trecan.2015.07.006&?
• What are the total earnings of https://doi.org/10.3390/cancers13215272?
• What's the financial intake of https://scholar.google.com/scholar_lookup?journal=Cancers%20(Basel)&title=Circulating%20tumor%20cell%20clusters%20are%20cloaked%20with%20platelets%20and%20correlate%20with%20poor%20prognosis%20in%20unresectable%20pancreatic%20cancer&author=M%20Lim&author=S%20Park&author=HO%20Jeong&author=SH%20Park&author=S%20Kumar&volume=13&issue=21&publication_year=2021&pmid=34771436&doi=10.3390/cancers13215272&?
• Discover the revenue of https://doi.org/10.1016/j.ccr.2011.09.009
• How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Cell&title=Direct%20signaling%20between%20platelets%20and%20cancer%20cells%20induces%20an%20epithelial-mesenchymal-like%20transition%20and%20promotes%20metastasis&author=M%20Labelle&author=S%20Begum&author=RO%20Hynes&volume=20&issue=5&publication_year=2011&pages=576-590&pmid=22094253&doi=10.1016/j.ccr.2011.09.009& net monthly?
• What's the monthly money flow for https://doi.org/10.1016/j.stem.2017.10.001?
• Earnings of https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=TGF-%CE%B2-Induced%20quiescence%20mediates%20chemoresistance%20of%20tumor-propagating%20cells%20in%20squamous%20cell%20carcinoma&author=JA%20Brown&author=Y%20Yonekubo&author=N%20Hanson&author=A%20Sastre-Perona&author=A%20Basin&volume=21&issue=5&publication_year=2017&pages=650-664,%20e8&pmid=29100014&doi=10.1016/j.stem.2017.10.001&
• What's the monthly money flow for https://doi.org/10.1158/0008-5472.CAN-17-1051?
• Monthly income for https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=Osteoblast-secreted%20factors%20mediate%20dormancy%20of%20metastatic%20prostate%20cancer%20in%20the%20bone%20via%20activation%20of%20the%20TGF%CE%B2RIII-p38MAPK-pS249/T252RB%20pathway&author=LY%20Yu-Lee&author=G%20Yu&author=YC%20Lee&author=SC%20Lin&author=J%20Pan&volume=78&issue=11&publication_year=2018&pages=2911-2924&pmid=29514796&doi=10.1158/0008-5472.CAN-17-1051&
• Financial intake of https://doi.org/10.1038/ncb2767
• How much cash flow does https://scholar.google.com/scholar_lookup?journal=Nat.%20Cell%20Biol&title=The%20perivascular%20niche%20regulates%20breast%20tumour%20dormancy&author=CM%20Ghajar&author=H%20Peinado&author=H%20Mori&author=IR%20Matei&author=KJ%20Evason&volume=15&issue=7&publication_year=2013&pages=807-817&pmid=23728425&doi=10.1038/ncb2767& have monthly?
• Get to know what's the income of https://doi.org/10.1016/j.cell.2016.02.025
• What's https://scholar.google.com/scholar_lookup?journal=Cell&title=Metastatic%20latency%20and%20immune%20evasion%20through%20autocrine%20inhibition%20of%20WNT&author=S%20Malladi&author=DG%20Macalinao&author=X%20Jin&author=L%20He&author=H%20Basnet&volume=165&issue=1&publication_year=2016&pages=45-60&pmid=27015306&doi=10.1016/j.cell.2016.02.025&'s gross income?
• Check the income stats for https://doi.org/10.1016/j.ccr.2012.09.022
• What are the total earnings of https://scholar.google.com/scholar_lookup?journal=Cancer%20Cell&title=Spatiotemporal%20regulation%20of%20epithelial-mesenchymal%20transition%20is%20essential%20for%20squamous%20cell%20carcinoma%20metastasis&author=JH%20Tsai&author=JL%20Donaher&author=DA%20Murphy&author=S%20Chau&author=J%20Yang&volume=22&issue=6&publication_year=2012&pages=725-736&pmid=23201165&doi=10.1016/j.ccr.2012.09.022&?
• How much does https://doi.org/10.1016/j.celrep.2013.11.014 rake in every month?
• How much does https://scholar.google.com/scholar_lookup?journal=Cell%20Rep&title=TGF-%CE%B2-Id1%20signaling%20opposes%20Twist1%20and%20promotes%20metastatic%20colonization%20via%20a%20mesenchymal-to-epithelial%20transition&author=M%20Stankic&author=S%20Pavlovic&author=Y%20Chin&author=E%20Brogi&author=D%20Padua&volume=5&issue=5&publication_year=2013&pages=1228-1242&pmid=24332369&doi=10.1016/j.celrep.2013.11.014& pull in?
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• Income figures for https://scholar.google.com/scholar_lookup?journal=Nature&title=Identification%20of%20the%20tumour%20transition%20states%20occurring%20during%20EMT&author=I%20Pastushenko&author=A%20Brisebarre&author=A%20Sifrim&author=M%20Fioramonti&author=T%20Revenco&volume=556&issue=7702&publication_year=2018&pages=463-468&pmid=29670281&doi=10.1038/s41586-018-0040-3&
• What's the total monthly financial gain of https://doi.org/10.1038/s41591-020-01195-4?
• Explore the financials of https://scholar.google.com/scholar_lookup?journal=Nat.%20Med&title=Targeting%20metastatic%20cancer&author=K%20Ganesh&author=J%20Massagu%C3%A9&volume=27&issue=1&publication_year=2021&pages=34-44&pmid=33442008&doi=10.1038/s41591-020-01195-4&
• Financial intake of https://doi.org/10.1158/2159-8290.CD-21-0010
• What's the income generated by https://scholar.google.com/scholar_lookup?journal=Cancer%20Disco&title=Metastasis-initiating%20cells%20and%20ecosystems&author=J%20Massagu%C3%A9&author=K%20Ganesh&volume=11&issue=4&publication_year=2021&pages=971-994&pmid=33811127&doi=10.1158/2159-8290.CD-21-0010& each month?
• Financial intake of https://doi.org/10.1038/nrm2455
• What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Nat.%20Rev.%20Mol.%20Cell%20Biol&title=Cancer%20as%20an%20overhealing%20wound:%20an%20old%20hypothesis%20revisited&author=M%20Sch%C3%A4fer&author=S%20Werner&volume=9&issue=8&publication_year=2008&pages=628-638&pmid=18628784&doi=10.1038/nrm2455&?
• What's the monthly money flow for https://doi.org/10.1056/NEJM199902113400604?
• What's the profit of https://scholar.google.com/scholar_lookup?journal=N.%20Engl.%20J.%20Med&title=Radial%20scars%20in%20benign%20breast-biopsy%20specimens%20and%20the%20risk%20of%20breast%20cancer&author=TW%20Jacobs&author=C%20Byrne&author=G%20Colditz&author=JL%20Connolly&author=SJ%20Schnitt&volume=340&issue=6&publication_year=1999&pages=430-436&pmid=9971867&doi=10.1056/NEJM199902113400604&?
• How much does https://doi.org/10.1001/archinte.168.21.2326 earn?
• How much does https://scholar.google.com/scholar_lookup?journal=Arch.%20Intern%20Med&title=Lung%20cancer%20risk%20following%20detection%20of%20pulmonary%20scarring%20by%20chest%20radiography%20in%20the%20prostate,%20lung,%20colorectal,%20and%20ovarian%20cancer%20screening%20trial&author=Y-Y%20Yu&author=PF%20Pinsky&author=NE%20Caporaso&author=N%20Chatterjee&author=M%20Baumgarten&volume=168&issue=21&publication_year=2008&pages=2326-2332&pmid=19029496&doi=10.1001/archinte.168.21.2326& bring in each month?
• Find out how much https://doi.org/10.1053/j.gastro.2019.03.050 earns monthly
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• How much profit is https://doi.org/10.1158/2159-8290.CD-19-0644 making per month?
• How profitable is https://scholar.google.com/scholar_lookup?journal=Cancer%20Disco&title=Single-cell%20RNA%20sequencing%20reveals%20stromal%20evolution%20into%20LRRC15(+)%20myofibroblasts%20as%20a%20determinant%20of%20patient%20response%20to%20cancer%20immunotherapy&author=CX%20Dominguez&author=S%20M%C3%BCller&author=S%20Keerthivasan&author=H%20Koeppen&author=J%20Hung&volume=10&issue=2&publication_year=2020&pages=232-253&pmid=31699795&doi=10.1158/2159-8290.CD-19-0644&?
• Profit of https://doi.org/10.7554/eLife.64811
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• Profit of https://github.com/ncbi
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• https://www.nih.gov/'s financial summary
• Find out how much https://www.hhs.gov/ earns monthly
• How much money does https://www.usa.gov/ make?

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