DOI . ORG {}

Analyzed Page
Matching Content Categories
CMS
Monthly Traffic Estimate
How Does Doi.org Make Money
Keywords
Topics
Questions
Schema
Social Networks
External Links
Analytics And Tracking
Libraries
Hosting Providers
CDN Services

We began analyzing https://www.nature.com/articles/nri.2017.125, but it redirected us to https://www.nature.com/articles/nri.2017.125. The analysis below is for the second page.

Title[redir]:
Microglia and macrophages in brain homeostasis and disease | Nature Reviews Immunology
Description:
This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.

Matching Content Categories {📚}

Education
Science
Business & Finance

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month

Based on our best estimate, this website will receive around 80,473,390 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Doi.org Make Money? {💸}

We can't tell how the site generates income.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Doi.org might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

pubmed, google, scholar, cas, central, microglia, nat, microglial, neurosci, nature, brain, cell, cells, macrophages, disease, development, system, alzheimers, immunol, function, neuron, article, science, stem, homeostasis, cns, tissueresident, access, adult, mouse, macrophage, human, immunity, rev, mice, trem, nervous, developmental, fate, monocytes, complement, receptor, myeloid, model, content, barres, functional, embryonic, postnatal, molecular,

Topics {✒️}

permissions reprints nature portfolio journals yolk-sac-derived erythro-myeloid progenitors privacy policy nature portfolio selective regional sensitivities author information authors advertising multi-centre case-control study single-cell rna-seq analyses unique tgf-β-dependent molecular social media editing genome-wide transcriptional profiling stroma-derived interleukin-34 controls neurodegeneration-specific gene-expression signature virus-induced memory impairment lineage-specific transcription factor cx3cr1/p38 mapk pathway prominent white-matter structure ipsc-derived human microglia ipsc-derived human microglia injured blood-brain barrier erythro-myeloid progenitors cell-mediated immune mechanisms unknown brain-derived signals maintain region-specific phenotypes precise nature pharmacological tools antigen–antibody immune complexes culture-specific expression profile nerve injury-induced cleavage personal data blood-brain barrier integrity neuron-restricted cytomegalovirus latency central nervous system vivo single-cell imaging tissue-resident macrophages originate transcription factor runx1 nature+ nature nature 518 nature 468 nature 497 nature 534 nature 530 nature 504 nature 532 nature 438 nature 505

Questions {❓}

A polarizing question: do M1 and M2 microglia exist?
Does niche competition determine the origin of tissue-resident macrophages?
Microglia: scapegoat, saboteur, or something else?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Microglia and macrophages in brain homeostasis and disease
         description: This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
         datePublished:2017-11-20T00:00:00Z
         dateModified:2017-11-20T00:00:00Z
         pageStart:225
         pageEnd:242
         sameAs:https://doi.org/10.1038/nri.2017.125
         keywords:
            Microglial cells
            Neuroimmunology
            Biomedicine
            general
            Immunology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Figa_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig4_HTML.jpg
         isPartOf:
            name:Nature Reviews Immunology
            issn:
               1474-1741
               1474-1733
            volumeNumber:18
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Qingyun Li
               affiliation:
                     name:Stanford University School of Medicine
                     address:
                        name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Ben A. Barres
               affiliation:
                     name:Stanford University School of Medicine
                     address:
                        name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Microglia and macrophages in brain homeostasis and disease
      description: This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
      datePublished:2017-11-20T00:00:00Z
      dateModified:2017-11-20T00:00:00Z
      pageStart:225
      pageEnd:242
      sameAs:https://doi.org/10.1038/nri.2017.125
      keywords:
         Microglial cells
         Neuroimmunology
         Biomedicine
         general
         Immunology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Figa_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig4_HTML.jpg
      isPartOf:
         name:Nature Reviews Immunology
         issn:
            1474-1741
            1474-1733
         volumeNumber:18
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Qingyun Li
            affiliation:
                  name:Stanford University School of Medicine
                  address:
                     name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Ben A. Barres
            affiliation:
                  name:Stanford University School of Medicine
                  address:
                     name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Reviews Immunology
      issn:
         1474-1741
         1474-1733
      volumeNumber:18
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Stanford University School of Medicine
      address:
         name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford University School of Medicine
      address:
         name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Qingyun Li
      affiliation:
            name:Stanford University School of Medicine
            address:
               name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Ben A. Barres
      affiliation:
            name:Stanford University School of Medicine
            address:
               name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
      name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

External Links {🔗}(639)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Prism.js
Zoom.js

Emails and Hosting {✉️}

Mail Servers:

mx.zoho.eu
mx2.zoho.eu
mx3.zoho.eu

Name Servers:

josh.ns.cloudflare.com
zita.ns.cloudflare.com

CDN Services {📦}

Crossref

5.6s.