Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/nri.2017.125.

Title:
Microglia and macrophages in brain homeostasis and disease | Nature Reviews Immunology
Description:
This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {πŸ“š}

  • Education
  • Science
  • Business & Finance

Content Management System {πŸ“}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {πŸ’Έ}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {πŸ’°}


Display Ads {🎯}

$63,100 per month
Estimations show Nature.com's display ad online revenue falls between $42,042 and $115,616 per month.

Keywords {πŸ”}

pubmed, google, scholar, cas, central, microglia, nat, microglial, neurosci, nature, brain, cell, cells, macrophages, disease, development, system, alzheimers, immunol, article, function, neuron, science, stem, homeostasis, cns, tissueresident, access, adult, mouse, macrophage, human, immunity, rev, mice, trem, nervous, developmental, fate, monocytes, complement, receptor, myeloid, model, content, barres, functional, embryonic, postnatal, molecular,

Topics {βœ’οΈ}

nature portfolio journals yolk-sac-derived erythro-myeloid progenitors permissions reprints privacy policy author information authors nature portfolio selective regional sensitivities advertising multi-centre case-control study single-cell rna-seq analyses unique tgf-Ξ²-dependent molecular social media editing genome-wide transcriptional profiling stroma-derived interleukin-34 controls neurodegeneration-specific gene-expression signature virus-induced memory impairment lineage-specific transcription factor cx3cr1/p38 mapk pathway prominent white-matter structure ipsc-derived human microglia ipsc-derived human microglia injured blood-brain barrier erythro-myeloid progenitors cell-mediated immune mechanisms unknown brain-derived signals maintain region-specific phenotypes precise nature pharmacological tools antigen–antibody immune complexes culture-specific expression profile nerve injury-induced cleavage personal data blood-brain barrier integrity neuron-restricted cytomegalovirus latency central nervous system vivo single-cell imaging tissue-resident macrophages originate abstract microglia transcription factor runx1 nature+ nature nature 518 nature 468 nature 497 nature 534 nature 530 nature 504 nature 532 nature 438

Questions {❓}

  • A polarizing question: do M1 and M2 microglia exist?
  • Does niche competition determine the origin of tissue-resident macrophages?
  • Microglia: scapegoat, saboteur, or something else?

Schema {πŸ—ΊοΈ}

WebPage:
      mainEntity:
         headline:Microglia and macrophages in brain homeostasis and disease
         description: This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
         datePublished:2017-11-20T00:00:00Z
         dateModified:2017-11-20T00:00:00Z
         pageStart:225
         pageEnd:242
         sameAs:https://doi.org/10.1038/nri.2017.125
         keywords:
            Microglial cells
            Neuroimmunology
            Biomedicine
            general
            Immunology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Figa_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig4_HTML.jpg
         isPartOf:
            name:Nature Reviews Immunology
            issn:
               1474-1741
               1474-1733
            volumeNumber:18
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Qingyun Li
               affiliation:
                     name:Stanford University School of Medicine
                     address:
                        name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Ben A. Barres
               affiliation:
                     name:Stanford University School of Medicine
                     address:
                        name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Microglia and macrophages in brain homeostasis and disease
      description: This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
      datePublished:2017-11-20T00:00:00Z
      dateModified:2017-11-20T00:00:00Z
      pageStart:225
      pageEnd:242
      sameAs:https://doi.org/10.1038/nri.2017.125
      keywords:
         Microglial cells
         Neuroimmunology
         Biomedicine
         general
         Immunology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Figa_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnri.2017.125/MediaObjects/41577_2018_Article_BFnri2017125_Fig4_HTML.jpg
      isPartOf:
         name:Nature Reviews Immunology
         issn:
            1474-1741
            1474-1733
         volumeNumber:18
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Qingyun Li
            affiliation:
                  name:Stanford University School of Medicine
                  address:
                     name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Ben A. Barres
            affiliation:
                  name:Stanford University School of Medicine
                  address:
                     name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Reviews Immunology
      issn:
         1474-1741
         1474-1733
      volumeNumber:18
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Stanford University School of Medicine
      address:
         name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
         type:PostalAddress
      name:Stanford University School of Medicine
      address:
         name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Qingyun Li
      affiliation:
            name:Stanford University School of Medicine
            address:
               name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Ben A. Barres
      affiliation:
            name:Stanford University School of Medicine
            address:
               name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
      name:Department of Neurobiology, Stanford University School of Medicine, Stanford, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {πŸ‘}(2)

External Links {πŸ”—}(411)

Analytics and Tracking {πŸ“Š}

  • Google Tag Manager

Libraries {πŸ“š}

  • Prism.js
  • Zoom.js

Emails and Hosting {βœ‰οΈ}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {πŸ“¦}

  • Crossref

4.56s.