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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
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We began analyzing https://www.nature.com/articles/nri.2017.125, but it redirected us to https://www.nature.com/articles/nri.2017.125. The analysis below is for the second page.

Title[redir]:
Microglia and macrophages in brain homeostasis and disease | Nature Reviews Immunology
Description:
This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.

Matching Content Categories {๐Ÿ“š}

  • Education
  • Science
  • Business & Finance

Content Management System {๐Ÿ“}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {๐Ÿ“ˆ}

What is the average monthly size of doi.org audience?

๐ŸŒ  Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {๐Ÿ’ธ}

We see no obvious way the site makes money.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Doi.org could be secretly minting cash, but we can't detect the process.

Keywords {๐Ÿ”}

pubmed, google, scholar, cas, central, microglia, nat, microglial, neurosci, nature, brain, cell, cells, macrophages, disease, development, system, alzheimers, immunol, function, neuron, article, science, stem, homeostasis, cns, tissueresident, access, adult, mouse, macrophage, human, immunity, rev, mice, trem, nervous, developmental, fate, monocytes, complement, receptor, myeloid, model, content, barres, functional, embryonic, postnatal, molecular,

Topics {โœ’๏ธ}

permissions reprints nature portfolio journals yolk-sac-derived erythro-myeloid progenitors privacy policy nature portfolio selective regional sensitivities author information authors advertising multi-centre case-control study single-cell rna-seq analyses unique tgf-ฮฒ-dependent molecular social media editing genome-wide transcriptional profiling stroma-derived interleukin-34 controls neurodegeneration-specific gene-expression signature virus-induced memory impairment lineage-specific transcription factor cx3cr1/p38 mapk pathway prominent white-matter structure ipsc-derived human microglia ipsc-derived human microglia injured blood-brain barrier erythro-myeloid progenitors cell-mediated immune mechanisms unknown brain-derived signals maintain region-specific phenotypes precise nature pharmacological tools antigenโ€“antibody immune complexes culture-specific expression profile nerve injury-induced cleavage personal data blood-brain barrier integrity neuron-restricted cytomegalovirus latency central nervous system vivo single-cell imaging tissue-resident macrophages originate transcription factor runx1 nature+ nature nature 518 nature 468 nature 497 nature 534 nature 530 nature 504 nature 532 nature 438 nature 505

Questions {โ“}

  • A polarizing question: do M1 and M2 microglia exist?
  • Does niche competition determine the origin of tissue-resident macrophages?
  • Microglia: scapegoat, saboteur, or something else?

Schema {๐Ÿ—บ๏ธ}

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         headline:Microglia and macrophages in brain homeostasis and disease
         description: This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
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      headline:Microglia and macrophages in brain homeostasis and disease
      description: This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases. Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that are increasingly recognized to be essential players in the development, homeostasis and diseases of the central nervous system. With the availability of new genetic, molecular and pharmacological tools, considerable advances have been made towards our understanding of the embryonic origins, developmental programmes and functions of these cells. These exciting discoveries, some of which are still controversial, also raise many new questions, which makes brain macrophage biology a fast-growing field at the intersection of neuroscience and immunology. Here, we review the current knowledge of how and where brain macrophages are generated, with a focus on parenchymal microglia. We also discuss their normal functions during development and homeostasis, the disturbance of which may lead to various neurodegenerative and neuropsychiatric diseases.
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Social Networks {๐Ÿ‘}(2)

External Links {๐Ÿ”—}(639)

Analytics and Tracking {๐Ÿ“Š}

  • Google Tag Manager

Libraries {๐Ÿ“š}

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Emails and Hosting {โœ‰๏ธ}

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