
NATURE . COM {
}
Title:
Maternal Caffeine Intake Has Minor Effects on Adenosine Receptor Ontogeny in the Rat Brain | Pediatric Research
Description:
Maternal caffeine intake has been suggested to influence the offspring. We have studied the effects of maternal caffeine intake on adenosine and GABA receptors, targets for caffeine, during development of the rat brain. Caffeine (0.3 g/L) was added to the drinking water of rat dams during pregnancy and early postnatal life. Adenosine A1 and A2A and GABAA receptor development was studied using receptor autoradiography and in situ hybridization. Pups were examined on embryonic d 14 (E14), E18, E21, 2 h after birth (P2h), P24h, postnatal d 3 (P3), P7, P14, and P21. Adenosine A1 receptor mRNA was detected at E14 and receptors at E18. A1 mRNA levels increased from the level reached at E18 between P3 and P14 (maximally a doubling), whereas A1 receptors, studied by [3H]-1,3-dipropyl-8-cyclopentyl xanthine binding, increased later and to a much larger extent (about 10-fold) postnatally. Caffeine treatment had no significant effect on adenosine A1 receptors or on A1 receptor mRNA. A2A mRNA had reached adult levels by E18, whereas receptor levels were low or undetectable before birth and increased dramatically until P14. Caffeine did not influence A2A receptors or A2A receptor mRNA at any stage during development. [3H]-flunitrazepam binding, representing GABAA receptors, showed large regional variations during ontogeny, but there were no clear differences between the caffeine-exposed and the nonexposed pups. Thus, exposure to a low dose of caffeine during gestation and postnatal life had only minor effects on development of adenosine A1 and A2A receptors and GABAA receptors in the rat brain.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Education
- Science
- Books & Literature
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,195,723 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$531,700 per month
Our analysis indicates Nature.com generates between $354,486 and $974,837 monthly online from display ads.
Keywords {π}
caffeine, receptors, binding, receptor, adenosine, brain, article, cas, google, scholar, mrna, rat, development, effects, present, fredholm, sections, nature, postnatal, pups, levels, doses, studies, detected, animals, study, hdpcpx, res, expression, results, studied, birth, treatment, controls, previous, intake, hybridization, low, research, ontogeny, water, autoradiography, situ, significant, dose, human, concentrations, plasma, rats, hcgs,
Topics {βοΈ}
nature portfolio permissions reprints privacy policy nature 377 nature scientific information advertising fresh solutions imaging research systems social media italy medical research striatal medium-sized neurons phenylethylamino]-5β²-n-ethylcarboxamido adenosine full size image [3h]-n-methyl-flunitrazepam ice-cold tris-hcl regional animal ethicscommittee g-protein coupled a2-receptors a1 receptor-rich areas ice-cold distilled water hypoxic-ischemic brain damage breast-feeding human mothers ten-micrometer-thick sections 3-dipropyl-8-cyclopentyl xanthine binding long-term theophylline treatment scandinavian gene systems r-n6-phenylisopropyladenosine neca permissions [3h]-flunitrazepam binding sites n-methyl-flunitrazepam middle panels middle panel reported long-term adaptive present data considered monsma fj jr phenylethylamino]-5β²-n-ethylcarboxamidoadenosine adenosine a2 receptor coffee-drinking human mothers agonist [3h]-cgs 21680 privacy 3-dipropyl-8-cyclopentyl xanthine a1 adenosine receptor therapeutic caffeine alters long-term behavioral gene expression xanthine adenosine antagonists term human fetus a1 mrna expression adenosine binding sites
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:Maternal Caffeine Intake Has Minor Effects on Adenosine Receptor Ontogeny in the Rat Brain
description:Maternal caffeine intake has been suggested to influence the offspring. We have studied the effects of maternal caffeine intake on adenosine and GABA receptors, targets for caffeine, during development of the rat brain. Caffeine (0.3 g/L) was added to the drinking water of rat dams during pregnancy and early postnatal life. Adenosine A1 and A2A and GABAA receptor development was studied using receptor autoradiography and in situ hybridization. Pups were examined on embryonic d 14 (E14), E18, E21, 2 h after birth (P2h), P24h, postnatal d 3 (P3), P7, P14, and P21. Adenosine A1 receptor mRNA was detected at E14 and receptors at E18. A1 mRNA levels increased from the level reached at E18 between P3 and P14 (maximally a doubling), whereas A1 receptors, studied by [3H]-1,3-dipropyl-8-cyclopentyl xanthine binding, increased later and to a much larger extent (about 10-fold) postnatally. Caffeine treatment had no significant effect on adenosine A1 receptors or on A1 receptor mRNA. A2A mRNA had reached adult levels by E18, whereas receptor levels were low or undetectable before birth and increased dramatically until P14. Caffeine did not influence A2A receptors or A2A receptor mRNA at any stage during development. [3H]-flunitrazepam binding, representing GABAA receptors, showed large regional variations during ontogeny, but there were no clear differences between the caffeine-exposed and the nonexposed pups. Thus, exposure to a low dose of caffeine during gestation and postnatal life had only minor effects on development of adenosine A1 and A2A receptors and GABAA receptors in the rat brain.
datePublished:
dateModified:
pageStart:177
pageEnd:183
sameAs:https://doi.org/10.1203/00006450-200008000-00010
keywords:
Medicine/Public Health
general
Pediatrics
Pediatric Surgery
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig4_HTML.jpg
isPartOf:
name:Pediatric Research
issn:
1530-0447
0031-3998
volumeNumber:48
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Ulrika ΓΒ
dΓΒ©n
affiliation:
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
type:Organization
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Eric Herlenius
affiliation:
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Lie-Qi Tang
affiliation:
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Bertil B Fredholm
affiliation:
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Maternal Caffeine Intake Has Minor Effects on Adenosine Receptor Ontogeny in the Rat Brain
description:Maternal caffeine intake has been suggested to influence the offspring. We have studied the effects of maternal caffeine intake on adenosine and GABA receptors, targets for caffeine, during development of the rat brain. Caffeine (0.3 g/L) was added to the drinking water of rat dams during pregnancy and early postnatal life. Adenosine A1 and A2A and GABAA receptor development was studied using receptor autoradiography and in situ hybridization. Pups were examined on embryonic d 14 (E14), E18, E21, 2 h after birth (P2h), P24h, postnatal d 3 (P3), P7, P14, and P21. Adenosine A1 receptor mRNA was detected at E14 and receptors at E18. A1 mRNA levels increased from the level reached at E18 between P3 and P14 (maximally a doubling), whereas A1 receptors, studied by [3H]-1,3-dipropyl-8-cyclopentyl xanthine binding, increased later and to a much larger extent (about 10-fold) postnatally. Caffeine treatment had no significant effect on adenosine A1 receptors or on A1 receptor mRNA. A2A mRNA had reached adult levels by E18, whereas receptor levels were low or undetectable before birth and increased dramatically until P14. Caffeine did not influence A2A receptors or A2A receptor mRNA at any stage during development. [3H]-flunitrazepam binding, representing GABAA receptors, showed large regional variations during ontogeny, but there were no clear differences between the caffeine-exposed and the nonexposed pups. Thus, exposure to a low dose of caffeine during gestation and postnatal life had only minor effects on development of adenosine A1 and A2A receptors and GABAA receptors in the rat brain.
datePublished:
dateModified:
pageStart:177
pageEnd:183
sameAs:https://doi.org/10.1203/00006450-200008000-00010
keywords:
Medicine/Public Health
general
Pediatrics
Pediatric Surgery
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1203%2F00006450-200008000-00010/MediaObjects/41390_2000_Article_BFpr2000174_Fig4_HTML.jpg
isPartOf:
name:Pediatric Research
issn:
1530-0447
0031-3998
volumeNumber:48
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Ulrika ΓΒ
dΓΒ©n
affiliation:
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
type:Organization
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Eric Herlenius
affiliation:
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Lie-Qi Tang
affiliation:
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
name:Bertil B Fredholm
affiliation:
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Pediatric Research
issn:
1530-0447
0031-3998
volumeNumber:48
Organization:
name:Nature Publishing Group US
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Ulrika ΓΒ
dΓΒ©n
affiliation:
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
type:Organization
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
name:Eric Herlenius
affiliation:
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
name:Lie-Qi Tang
affiliation:
name:Astrid Lindgren Childen's Hospital, S-171 76
address:
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
type:PostalAddress
type:Organization
name:Bertil B Fredholm
affiliation:
name:Karolinska Institute, S-171 77
address:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
type:PostalAddress
type:Organization
PostalAddress:
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
name:Department of Woman and Child Health, Astrid Lindgren Childen's Hospital, S-171 76, Stockholm, Sweden
name:Department of Physiology and Pharmacology, Karolinska Institute, S-171 77, Stockholm, Sweden
External Links {π}(107)
- What are the earnings of https://mc04.manuscriptcentral.com/prjournal?
- What are the earnings of https://doi.org/10.1097%2F00001648-199109000-00011?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Coffee%20consumption%2C%20birthweight%2C%20and%20reproductive%20failures&journal=Epidemiology&doi=10.1097%2F00001648-199109000-00011&volume=2&pages=370-374&publication_year=1991&author=Olsen%2CJ&author=Overvad%2CK&author=Frische%2CG
- How much money does https://doi.org/10.1159%2F000299032 make?
- http://scholar.google.com/scholar_lookup?&title=Effects%20of%20caffeine%20ingestion%20during%20pregnancy&journal=Gynecol%20Obstet%20Invest&doi=10.1159%2F000299032&volume=19&pages=187-191&publication_year=1985&author=Furuhashi%2CN&author=Sato%2CS&author=Suzuki%2CM&author=Hiruta%2CM&author=Tanaka%2CM&author=Takahashi%2CT's total income per month
- How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1623464 have?
- Financial intake of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1336160
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Smoking%20and%20caffeine%20and%20alcohol%20intake%20during%20pregnancy%20in%20a%20northern%20population%3A%20effect%20on%20fetal%20growth&journal=CMAJ&volume=147&pages=181-188&publication_year=1992&author=Godel%2CJC&author=Pabst%2CHF&author=Hodges%2CPE&author=Johnson%2CKE&author=Froese%2CGJ&author=Joffres%2CMR is on a monthly basis
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Neurobehavioral%20teratology%20of%20caffeine%20exposure%20in%20rats&journal=Neurotoxicology&volume=1&pages=403-416&publication_year=1979&author=Sobotka%2CTJ&author=Spaid%2CSL&author=Brodie%2CRE?
- How much income does https://link.springer.com/doi/10.1007/BF00433505 have?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Gestational%20caffeine%20modifies%20offspring%20behaviour%20in%20mice&journal=Psychopharmacology&doi=10.1007%2FBF00433505&volume=75&pages=69-74&publication_year=1981&author=Sinton%2CCM&author=Valatx%2CJL&author=Jouvet%2CM produce monthly?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7070566 produce monthly?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Caffeine%3A%20effects%20of%20acute%20and%20chronic%20exposure%20on%20the%20behavior%20of%20neonatal%20rats&journal=Neurobehav%20Toxicol%20Teratol&volume=4&pages=21-32&publication_year=1982&author=Holloway%2CWR?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Actions%20of%20caffeine%20in%20the%20brain%20with%20special%20reference%20to%20factors%20that%20contribute%20to%20its%20widespread%20use&journal=Pharmacol%20Rev&volume=51&pages=83-133&publication_year=1999&author=Fredholm%2CBB&author=Battig%2CK&author=Holmen%2CJ&author=Nehlig%2CA&author=Zvartau%2CEE?
- How profitable is https://doi.org/10.1016%2F0165-3806%2895%2900120-3?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=The%20ontogeny%20of%20cardiac%20and%20neural%20A1%20adenosine%20receptor%20expression%20in%20rats&journal=Brain%20Res%20Dev%20Brain%20Res&doi=10.1016%2F0165-3806%2895%2900120-3&volume=89&pages=202-213&publication_year=1995&author=Rivkees%2CSA
- How much revenue does https://doi.org/10.1016%2F0169-328X%2893%2990058-W produce monthly?
- http://scholar.google.com/scholar_lookup?&title=A2a%20adenosine%20receptor%20gene%20expression%20in%20developing%20rat%20brain&journal=Brain%20Res%20Mol%20Brain%20Res&doi=10.1016%2F0169-328X%2893%2990058-W&volume=20&pages=313-327&publication_year=1993&author=Weaver%2CDR's total income per month
- Get to know https://doi.org/10.1016%2FS0165-3806%2896%2980013-7's earnings
- How much does http://scholar.google.com/scholar_lookup?&title=A1-adenosine%20receptor%20gene%20expression%20in%20fetal%20rat%20brain&journal=Brain%20Res%20Dev%20Brain%20Res&doi=10.1016%2FS0165-3806%2896%2980013-7&volume=94&pages=205-223&publication_year=1996&author=Weaver%2CDR pull in?
- How much profit does https://doi.org/10.1016%2FS0306-4522%2897%2900143-7 make?
- http://scholar.google.com/scholar_lookup?&title=Distribution%20and%20postnatal%20ontogeny%20of%20adenosine%20A2A%20receptors%20in%20rat%20brain%3A%20comparison%20with%20dopamine%20receptors&journal=Neuroscience&doi=10.1016%2FS0306-4522%2897%2900143-7&volume=80&pages=1187-1207&publication_year=1997&author=Johansson%2CB&author=Georgiev%2CV&author=Fredholm%2CBB's total income per month
- How much profit does https://doi.org/10.1111%2Fj.1471-4159.1982.tb04732.x generate?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Ontogeny%20of%20adenosine%20binding%20sites%20in%20rat%20forebrain%20and%20cerebellum&journal=J%20Neurochem&doi=10.1111%2Fj.1471-4159.1982.tb04732.x&volume=39&pages=267-270&publication_year=1982&author=Marangos%2CPJ&author=Patel%2CJ&author=Stivers%2CJ
- How much does https://doi.org/10.1016%2F0306-4522%2892%2990291-9 pull in monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Adenosine-dopamine%20interactions%20in%20the%20brain&journal=Neuroscience&doi=10.1016%2F0306-4522%2892%2990291-9&volume=51&pages=501-512&publication_year=1992&author=Ferre%2CS&author=Fuxe%2CK&author=von%20Euler%2CG&author=Johansson%2CB&author=Fredholm%2CBB generate?
- Financial intake of https://doi.org/10.1016%2FS0301-0082%2899%2900011-8
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Distribution%2C%20biochemistry%20and%20function%20of%20striatal%20adenosine%20A2A%20receptors&journal=Prog%20Neurobiol&doi=10.1016%2FS0301-0082%2899%2900011-8&volume=59&pages=355-396&publication_year=1999&author=Svenningsson%2CP&author=Le%20Moine%2CC&author=Fisone%2CG&author=Fredholm%2CBB?
- How much income does https://doi.org/10.1038%2F377424a0 have?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Parkinsonian-like%20locomotor%20impairment%20in%20mice%20lacking%20dopamine%20D2%20receptors&journal=Nature&doi=10.1038%2F377424a0&volume=377&pages=424-428&publication_year=1995&author=Baik%2CJH&author=Picetti%2CR&author=Saiardi%2CA&author=Thiriet%2CG&author=Dierich%2CA&author=Depaulis%2CA&author=Le%20Meur%2CM&author=Borrelli%2CE
- How much does https://link.springer.com/doi/10.1007/BF00733753 gross monthly?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Chronic%20caffeine%20alters%20the%20density%20of%20adenosine%2C%20adrenergic%2C%20cholinergic%2C%20GABA%2C%20and%20serotonin%20receptors%20and%20calcium%20channels%20in%20mouse%20brain&journal=Cell%20Mol%20Neurobiol&doi=10.1007%2FBF00733753&volume=13&pages=247-261&publication_year=1993&author=Shi%2CD&author=Nikodijevic%2CO&author=Jacobson%2CKA&author=Daly%2CJW?
- Monthly income for https://doi.org/10.1016%2F0306-3623%2886%2990203-X
- How much money does http://scholar.google.com/scholar_lookup?&title=Up-regulation%20of%20brain%20%5B3H%5Ddiazepam%20binding%20sites%20in%20chronic%20caffeine%20treated%20rats&journal=Gen%20Pharmacol&doi=10.1016%2F0306-3623%2886%2990203-X&volume=17&pages=501-503&publication_year=1986&author=Wu%2CPH&author=Phillis%2CJW make?
- Explore the financials of https://doi.org/10.1016%2F0304-3940%2882%2990290-7
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Effects%20of%20caffeine%20and%20theophylline%20on%20adenosine%20and%20benzodiazepine%20receptors%20in%20human%20brain&journal=Neurosci%20Lett&doi=10.1016%2F0304-3940%2882%2990290-7&volume=30&pages=161-166&publication_year=1982&author=Boulenger%2CJP&author=Patel%2CJ&author=Marangos%2CPJ have monthly?
- How much does https://doi.org/10.1111%2Fj.1460-9568.1996.tb01539.x pull in?
- How much does http://scholar.google.com/scholar_lookup?&title=Long-term%20treatment%20with%20some%20methylxanthines%20decreases%20the%20susceptibility%20to%20bicuculline-%20and%20pentylenetetrazol-induced%20seizures%20in%20mice&journal=Eur%20J%20Neurosci&doi=10.1111%2Fj.1460-9568.1996.tb01539.x&volume=8&pages=2447-2458&publication_year=1996&author=Johansson%2CB&author=Georgiev%2CV&author=Kuosmanen%2CT&author=Fredholm%2CBB generate monthly?
- https://doi.org/10.1016%2F0922-4106%2889%2990028-X's revenue stream
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Interaction%20of%20caffeine%20with%20the%20GABAA%20receptor%20complex%3A%20alterations%20in%20receptor%20function%20but%20not%20ligand%20binding&journal=Eur%20J%20Pharmacol&doi=10.1016%2F0922-4106%2889%2990028-X&volume=172&pages=453-459&publication_year=1989&author=Lopez%2CF&author=Miller%2CLG&author=Greenblatt%2CDJ&author=Kaplan%2CGB&author=Shader%2CRI
- How much revenue does https://doi.org/10.1016%2F0028-3908%2891%2990011-Y produce monthly?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Neonatal%20exposure%20to%20therapeutic%20caffeine%20alters%20the%20ontogeny%20of%20adenosine%20A1%20receptors%20in%20brain%20of%20rats&journal=Neuropharmacology&doi=10.1016%2F0028-3908%2891%2990011-Y&volume=30&pages=489-496&publication_year=1991&author=Guillet%2CR&author=Kellogg%2CC bring in?
- Get to know what's the income of https://doi.org/10.1016%2F0165-3806%2894%2990165-1
- Profit of http://scholar.google.com/scholar_lookup?&title=Effects%20of%20neonatal%20exposure%20to%20caffeine%20on%20adenosine%20A1%20receptor%20ontogeny%20using%20autoradiography&journal=Brain%20Res%20Dev%20Brain%20Res&doi=10.1016%2F0165-3806%2894%2990165-1&volume=82&pages=223-230&publication_year=1994&author=Etzel%2CBA&author=Guillet%2CR
- How much income does https://doi.org/10.1016%2F0024-3205%2884%2990207-8 have?
- What's http://scholar.google.com/scholar_lookup?&title=Effects%20of%20chronic%20caffeine%20on%20brain%20adenosine%20receptors%3A%20regional%20and%20ontogenetic%20studies&journal=Life%20Sci&doi=10.1016%2F0024-3205%2884%2990207-8&volume=34&pages=899-907&publication_year=1984&author=Marangos%2CPJ&author=Boulenger%2CJP&author=Patel%2CJ's gross income?
- https://doi.org/10.1203%2F00006450-199509000-00007's financial summary
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20effect%20of%20long%20term%20caffeine%20treatment%20on%20hypoxic-ischemic%20brain%20damage%20in%20the%20neonate&journal=Pediatr%20Res&doi=10.1203%2F00006450-199509000-00007&volume=38&pages=312-318&publication_year=1995&author=Bona%2CE&author=Aden%2CU&author=Fredholm%2CBB&author=Hagberg%2CH bring in?
- What is the monthly revenue of https://doi.org/10.1111%2Fj.1651-2227.1997.tb18353.x?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Hypoxia-ischaemia%20model%20in%20the%207-day-old%20rat%3A%20possibilities%20and%20shortcomings&journal=Acta%20Paediatr%20Suppl&doi=10.1111%2Fj.1651-2227.1997.tb18353.x&volume=422&pages=85-88&publication_year=1997&author=Hagberg%2CH&author=Bona%2CE&author=Gilland%2CE&author=Puka-Sundvall%2CM?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2539455 income
- How much profit does http://scholar.google.com/scholar_lookup?&title=Relationship%20of%20plasma%20and%20brain%20concentrations%20of%20caffeine%20and%20metabolites%20to%20benzodiazepine%20receptor%20binding%20and%20locomotor%20activity&journal=J%20Pharmacol%20Exp%20Ther&volume=248&pages=1078-1083&publication_year=1989&author=Kaplan%2CGB&author=Greenblatt%2CDJ&author=Leduc%2CBW&author=Thompson%2CML&author=Shader%2CRI make?
- What is the earnings of https://doi.org/10.1016%2F0006-8993%2890%2990272-D?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Effects%20of%20long-term%20theophylline%20treatment%20on%20adenosine%20A1-receptors%20in%20rat%20brain%3A%20autoradiographic%20evidence%20for%20increased%20receptor%20number%20and%20altered%20coupling%20to%20G-proteins&journal=Brain%20Res&doi=10.1016%2F0006-8993%2890%2990272-D&volume=507&pages=195-199&publication_year=1990&author=Fastbom%2CJ&author=Fredholm%2CBB
- How much revenue does https://link.springer.com/doi/10.1007/BF00178977 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Autoradiographic%20evidence%20for%20G-protein%20coupled%20A2-receptors%20in%20rat%20neostriatum%20using%20%5B3H%5D-CGS%2021680%20as%20a%20ligand&journal=Naunyn%20Schmiedebergs%20Arch%20Pharmacol&doi=10.1007%2FBF00178977&volume=342&pages=85-89&publication_year=1990&author=Parkinson%2CFE&author=Fredholm%2CBB make?
- Learn about the earnings of https://doi.org/10.1046%2Fj.1471-4159.1998.70031210.x
- How much revenue does http://scholar.google.com/scholar_lookup?&title=%5B3H%5DSCH%2058261%2C%20a%20selective%20A2A%20adenosine%20receptor%20antagonist%2C%20is%20a%20useful%20ligand%20in%20autoradiographic%20studies&journal=J%20Neurochem&doi=10.1046%2Fj.1471-4159.1998.70031210.x&volume=70&pages=1210-1216&publication_year=1998&author=Fredholm%2CBB&author=Lindstr%C3%B6m%2CK&author=Dionisotti%2CS&author=Ongini%2CE bring in?
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1857334
- What's http://scholar.google.com/scholar_lookup?&title=Cloning%20and%20expression%20of%20an%20A1%20adenosine%20receptor%20from%20rat%20brain&journal=Mol%20Pharmacol&volume=40&pages=1-7&publication_year=1991&author=Mahan%2CLC&author=McVittie%2CLD&author=Smyk-Randall%2CEM&author=Nakata%2CH&author=Monsma%2CFJ&author=Gerfen%2CCR&author=Sibley%2CDR's gross income?
- How much profit does https://doi.org/10.1016%2F0006-8993%2890%2990097-U generate?
- What's http://scholar.google.com/scholar_lookup?&title=A%20cloned%20G%20protein-coupled%20protein%20with%20a%20distribution%20restricted%20to%20striatal%20medium-sized%20neurons&journal=Brain%20Res&doi=10.1016%2F0006-8993%2890%2990097-U&volume=519&pages=333-337&publication_year=1990&author=Schiffmann%2CSN&author=Libert%2CF&author=Vassart%2CG&author=Dumont%2CJE&author=Vanderhaeghen%2CJJ's gross income?
- How much profit does https://link.springer.com/doi/10.1007/BF00165391 make?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Effect%20of%20long%20term%20caffeine%20treatment%20on%20A1%20and%20A2%20adenosine%20receptor%20binding%20and%20on%20mRNA%20levels%20in%20rat%20brain&journal=Naunyn%20Schmiedebergs%20Arch%20Pharmacol&doi=10.1007%2FBF00165391&volume=347&pages=407-414&publication_year=1993&author=Johansson%2CB&author=Ahlberg%2CS&author=van%20der%20Ploeg%2CI&author=Brene%2CS&author=Lindefors%2CN&author=Persson%2CH&author=Fredholm%2CBB generate?
- How much profit does https://doi.org/10.1016%2F0006-8993%2894%2991066-9 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Evidence%20for%20functionally%20important%20adenosine%20A2a%20receptors%20in%20the%20rat%20hippocampus&journal=Brain%20Res&doi=10.1016%2F0006-8993%2894%2991066-9&volume=649&pages=208-216&publication_year=1994&author=Cunha%2CRA&author=Johansson%2CB&author=van%20der%20Ploeg%2CI&author=Sebastiao%2CAM&author=Ribeiro%2CJA&author=Fredholm%2CBB generate monthly?
- What's the financial outcome of https://doi.org/10.1021%2Fjm00094a022?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Adenosine%20A1%20antagonists&journal=J%20Med%20Chem&doi=10.1021%2Fjm00094a022&volume=35&pages=3066-3075&publication_year=1992&author=Suzuki%2CF&author=Shimada%2CJ&author=Mizumoto%2CH&author=Karasawa%2CA&author=Kubo%2CK&author=Nonaka%2CH&author=Ishii%2CA&author=Kawakita%2CT?
- How much profit does https://doi.org/10.1016%2F0306-4522%2887%2992962-9 generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Adenosine%20A1%20receptors%20in%20the%20human%20brain%3A%20a%20quantitative%20autoradiographic%20study&journal=Neuroscience&doi=10.1016%2F0306-4522%2887%2992962-9&volume=22&pages=827-839&publication_year=1987&author=Fastbom%2CJ&author=Pazos%2CA&author=Probst%2CA&author=Palacios%2CJM bring in?
- How much does https://doi.org/10.1523%2FJNEUROSCI.19-10-04011.1999 generate monthly?
- Earnings of http://scholar.google.com/scholar_lookup?&title=The%20stimulatory%20action%20and%20the%20development%20of%20tolerance%20to%20caffeine%20is%20associated%20with%20alterations%20in%20gene%20expression%20in%20specific%20brain%20regions&journal=J%20Neurosci&doi=10.1523%2FJNEUROSCI.19-10-04011.1999&volume=19&pages=4011-4022&publication_year=1999&author=Svenningsson%2CP&author=Nomikos%2CGG&author=Fredholm%2CBB
- How much does https://doi.org/10.1523%2FJNEUROSCI.03-07-01478.1983 generate monthly?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=An%20autoradiographic%20study%20of%20the%20prenatal%20development%20of%20benzodiazepine-binding%20sites%20in%20rat%20brain&journal=J%20Neurosci&doi=10.1523%2FJNEUROSCI.03-07-01478.1983&volume=3&pages=1478-1487&publication_year=1983&author=Schlumpf%2CM&author=Richards%2CJG&author=Lichtensteiger%2CW&author=Mohler%2CH?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Caffeine%3A%20metabolism%20and%20biochemical%20mechanisms%20of%20action&journal=Nutr%20Brain&volume=6&pages=1-30&publication_year=1983&author=Neims%2CA&author=von%20Borstel%2CRW bring in?
- Revenue of https://doi.org/10.1159%2F000457057
- Find out how much http://scholar.google.com/scholar_lookup?&title=Caffeine%20in%20human%20milk%20and%20in%20serum%20of%20breast-fed%20infants&journal=Dev%20Pharmacol%20Ther&doi=10.1159%2F000457057&volume=8&pages=329-337&publication_year=1985&author=Ryu%2CJE earns monthly
- What's the financial outcome of https://doi.org/10.1016%2FS0022-3476%2881%2980784-6?
- How much does http://scholar.google.com/scholar_lookup?&title=Prolonged%20half-life%20of%20caffeine%20in%20healthy%20term%20newborn%20infants&journal=J%20Pediat&doi=10.1016%2FS0022-3476%2881%2980784-6&volume=98&pages=640-641&publication_year=1981&author=Parsons%2CWD&author=Neims%2CAH pull in?
- What's the income generated by https://doi.org/10.1159%2F000457627 each month?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Neonatal%20caffeine%20exposure%20alters%20adenosine%20receptor%20control%20of%20locomotor%20activity%20in%20the%20developing%20rat&journal=Dev%20Pharmacol%20Ther&doi=10.1159%2F000457627&volume=15&pages=94-100&publication_year=1990&author=Guillet%2CR have monthly?
- Learn how profitable https://link.springer.com/doi/10.1007/PL00005131 is on a monthly basis
- How much does http://scholar.google.com/scholar_lookup?&title=Comparative%20pharmacology%20of%20human%20adenosine%20receptor%20subtypes%E2%80%94characterization%20of%20stably%20transfected%20receptors%20in%20CHO%20cells&journal=Naunyn%20Schmiedebergs%20Arch%20Pharmacol&doi=10.1007%2FPL00005131&volume=357&pages=1-9&publication_year=1998&author=Klotz%2CKN&author=Hessling%2CJ&author=Hegler%2CJ&author=Owman%2CC&author=Kull%2CB&author=Fredholm%2CBB&author=Lohse%2CMJ rake in every month?
- Monthly income for https://doi.org/10.1002%2Fcne.903170202
- Get to know http://scholar.google.com/scholar_lookup?&title=Ontogeny%20of%20gene%20expression%20of%20adenosine%20A2%20receptor%20in%20the%20striatum%3A%20early%20localization%20in%20the%20patch%20compartment&journal=J%20Comp%20Neurol&doi=10.1002%2Fcne.903170202&volume=317&pages=117-128&publication_year=1992&author=Schiffmann%2CSN&author=Vanderhaeghen%2CJJ's earnings
- How much profit is https://doi.org/10.1016%2F0028-3908%2895%2900009-U making per month?
- How much does http://scholar.google.com/scholar_lookup?&title=Further%20characterization%20of%20the%20binding%20of%20the%20adenosine%20receptor%20agonist%20%5B3H%5DCGS%2021680%20to%20rat%20brain%20using%20autoradiography&journal=Neuropharmacology&doi=10.1016%2F0028-3908%2895%2900009-U&volume=34&pages=393-403&publication_year=1995&author=Johansson%2CB&author=Fredholm%2CBB rake in every month?
- What's the revenue for https://citation-needed.springer.com/v2/references/10.1203/00006450-200008000-00010?format=refman&flavour=references?
- How much profit does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ulrika%20%C3%85d%C3%A9n make?
- How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ulrika%20%C3%85d%C3%A9n%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Eric%20Herlenius?
- How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Eric%20Herlenius%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What is the monthly revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lie-Qi%20Tang?
- What's the monthly income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lie-Qi%20Tang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the monthly money flow for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Bertil%20B%20Fredholm?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Bertil%20B%20Fredholm%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
- How much revenue does https://s100.copyright.com/AppDispatchServlet?title=Maternal%20Caffeine%20Intake%20Has%20Minor%20Effects%20on%20Adenosine%20Receptor%20Ontogeny%20in%20the%20Rat%20Brain&author=Ulrika%20%C3%85d%C3%A9n%20et%20al&contentID=10.1203%2F00006450-200008000-00010©right=International%20Pediatrics%20Research%20Foundation%2C%20Inc.&publication=0031-3998&publicationDate=2000-08-01&publisherName=SpringerNature&orderBeanReset=true generate?
- Get to know https://citation-needed.springer.com/v2/references/10.1203/00006450-200008000-00010?format=refman&flavour=citation's earnings
- How much income is https://doi.org/10.1007/s11011-021-00829-x earning monthly?
- How much does https://doi.org/10.1007/s11910-019-0948-5 bring in each month?
- Learn about the earnings of https://doi.org/10.1007/s00429-015-1072-1
- How much does https://doi.org/10.1007/s11064-011-0577-0 bring in each month?
- What is the earnings of https://doi.org/10.1007/s00702-008-0055-2?
- Earnings of https://www.protocols.io/
- https://www.natureindex.com/'s revenue stream
- How much does http://www.naturechina.com pull in monthly?
- How much does https://www.natureasia.com/ja-jp rake in every month?
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk