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NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
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We are analyzing https://www.nature.com/articles/nrc.2017.125.

Title:
Targeting minimal residual disease: a path to cure? | Nature Reviews Cancer
Description:
Improved therapies have allowed many patients with cancer to achieve complete remission, but they retain minimal residual disease (MRD), which causes relapse. This Opinion article argues that iterative detection, profiling and targeting of MRD could improve outcomes, including cure rates. Therapeutics that block kinases, transcriptional modifiers, immune checkpoints and other biological vulnerabilities are transforming cancer treatment. As a result, many patients achieve dramatic responses, including complete radiographical or pathological remission, yet retain minimal residual disease (MRD), which results in relapse. New functional approaches can characterize clonal heterogeneity and predict therapeutic sensitivity of MRD at a single-cell level. Preliminary evidence suggests that iterative detection, profiling and targeting of MRD would meaningfully improve outcomes and may even lead to cure.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Science

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🚀🌠 Tremendous Traffic: 10M - 20M visitors per month


Based on our best estimate, this website will receive around 17,334,432 visitors per month in the current month.

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How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$218,500 per month
Our calculations suggest that Nature.com earns between $145,651 and $400,541 monthly online from display advertisements.

Keywords {🔍}

pubmed, article, scholar, google, cas, cancer, central, leukemia, oncol, residual, acute, nature, disease, nat, cell, clin, blood, minimal, patients, cells, myeloid, singlecell, lymphoblastic, clinical, chemotherapy, med, therapy, access, phase, study, rev, content, treatment, research, breast, tumor, circulating, mrd, lung, trial, engl, sci, usa, chronic, results, heterogeneity, detection, versus, flow, response,

Topics {✒️}

nature portfolio journals permissions reprints nature portfolio privacy policy index tonsillar carcinomas interrogating open issues author information authors advertising single-cell rna-seq supports integrative cancer research national library scientific adviser receives research funding social media open-label dana-farber cancer institute nature+ nature 435 nature 539 nature 518 nature single-cell rna-seq guide therapy decision-making research hospital intraductal papillary-mucinous tumors live-cell mass profiling single-cell transcriptomics applied empowering single-cell 'omics' low-cost rna sequencing small-cell lung cancer gov/ct2/show/nct02478125 muscle-invasive bladder cancer single-cell mass accumulation stop 2g-tki study xenografts enables discovery single-cell growth rates circulating-free tumor dna early breast cancer moving treatment-free remission real-time deformability cytometry permissions egfr-mutant nsclc patients springerlink instant access fixable bh3 profiling gastrointestinal stromal tumors predicting patient responses flow cytometric monitoring chronic myeloid leukaemia metastatic breast cancer phase iii randomized

Questions {❓}

  • Does the mobilization of circulating tumour cells during cancer therapy cause metastasis?
  • Has MRD monitoring superseded other prognostic factors in adult ALL?
  • MRD in AML: does it already guide therapy decision-making?
  • Targeting minimal residual disease: a path to cure?
  • Targeting minimal residual disease: a path to cure?

Schema {🗺️}

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         description:Improved therapies have allowed many patients with cancer to achieve complete remission, but they retain minimal residual disease (MRD), which causes relapse. This Opinion article argues that iterative detection, profiling and targeting of MRD could improve outcomes, including cure rates. Therapeutics that block kinases, transcriptional modifiers, immune checkpoints and other biological vulnerabilities are transforming cancer treatment. As a result, many patients achieve dramatic responses, including complete radiographical or pathological remission, yet retain minimal residual disease (MRD), which results in relapse. New functional approaches can characterize clonal heterogeneity and predict therapeutic sensitivity of MRD at a single-cell level. Preliminary evidence suggests that iterative detection, profiling and targeting of MRD would meaningfully improve outcomes and may even lead to cure.
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Social Networks {👍}(2)

External Links {🔗}(454)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
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Name Servers:

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  • pdns2.ultradns.net
  • pdns3.ultradns.org
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  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

5.23s.