NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Photography

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,555,829 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$536,300 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $357,511 to $983,155.

Keywords {🔍}

klf, cells, differentiation, expression, klfkd, endoderm, article, control, cell, fig, google, scholar, genes, mesoderm, markers, knockdown, cas, sox, gata, stem, esgscgfpsoxhucdklfkd, mouse, definitive, klfoe, clones, mixl, embryonic, factors, endodermal, visceral, mesodermal, gene, performed, supplementary, increased, analysis, results, observed, teratomas, nature, gfp, fold, expressing, level, data, induced, day, showed, promoter, nanog,

Topics {✒️}

nature portfolio permissions reprints privacy policy fluorescein-anti-mouse e-cadherin mab es-gscgfpsox17hucd25-klf5-kd clones exhibited advertising es-gscgfpsox17hucd25-klf4-kd clones exhibited ultra-high-throughput dna sequencing es-gscgfpsox17hucd25-klf4-kd cells exhibited es-gscgfpsox17hucd25-klf5-kd clones showed es-gscgfpsox17hucd25-klf4-kd clones showed south china institute apc-anti-human cd25 mab lif-deprived serum-free medium brain research institute apc-anti-mouse flk1 mab social media rnaeasy kits sox17-dsred-klf5-kd es cells pierre-yves bourillot michael xavier doss resulting es-gscgfpsox17hucd25-klf4-kd nature 343 nature 489 nature es-gscgfpsox17hucd25-klf5-kd clones es-gscgfpsox17hucd25-klf4-kd cells apc-anti-mouse cd140a evolutionarily conserved zinc-finger full access produce siv-derived lentivectors klf5-kd cells-derived teratomas context-dependent opposing forces klf4-kd cells-derived teratomas collagen iv-coated dishes klf5-kd2 cells-derived teratomas accession numbers e-mtab-1838 pgae-cag-egfp-wpre46 research grants generated es-gscgfpsox17hucd25 subclones quantitative real-time pcr embryo-derived stem cells extracellular cysteine-rich domain es-gscgfpsox17hucd25-klf5-kd real-time pcr analysis identify mucin-expressing epithelium klf5-kd clones exhibited es-gscgfpsox17hucd25-klf4-kd pre-implantation mouse embryo pgae-cag-klf5-wpre

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells
         description:Krüppel-like factors (Klf) 4 and 5 are two closely related members of the Klf family, known to play key roles in cell cycle regulation, somatic cell reprogramming and pluripotency. Here we focus on the functional divergence between Klf4 and Klf5 in the inhibition of mouse embryonic stem (ES) cell differentiation. Using microarrays and chromatin immunoprecipitation coupled to ultra-high-throughput DNA sequencing, we show that Klf4 negatively regulates the expression of endodermal markers in the undifferentiated ES cells, including transcription factors involved in the commitment of pluripotent stem cells to endoderm differentiation. Knockdown of Klf4 enhances differentiation towards visceral and definitive endoderm. In contrast, Klf5 negatively regulates the expression of mesodermal markers, some of which control commitment to the mesoderm lineage, and knockdown of Klf5 specifically enhances differentiation towards mesoderm. We conclude that Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in murine ES cells. The Krüppel-like factors Klf4 and Klf5 have wide roles in cell biology including the regulation of pluripotency. In this study, Aksoy et al. demonstrate that Klf4 preferentially blocks the expression of endodermal markers in embryonic stem cells, whereas Klf5 negatively regulates mesodermal factors.
         datePublished:2014-04-28T00:00:00Z
         dateModified:2014-04-28T00:00:00Z
         pageStart:1
         pageEnd:15
         sameAs:https://doi.org/10.1038/ncomms4719
         keywords:
            Cell signalling
            Embryogenesis
            Stem-cell differentiation
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Figa_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig5_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig6_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig7_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig8_HTML.jpg
         isPartOf:
            name:Nature Communications
            issn:
               2041-1723
            volumeNumber:5
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Irène Aksoy
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Vincent Giudice
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Edwige Delahaye
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Florence Wianny
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Maxime Aubry
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Magali Mure
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jiaxuan Chen
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ralf Jauch
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
                     name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
                     address:
                        name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gireesh K. Bogu
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tobias Nolden
               affiliation:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                     address:
                        name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Heinz Himmelbauer
               affiliation:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                     address:
                        name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                        type:PostalAddress
                     type:Organization
                     name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
                     address:
                        name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                     address:
                        name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael Xavier Doss
               affiliation:
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                     address:
                        name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
                     address:
                        name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Agapios Sachinidis
               affiliation:
                     name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
                     address:
                        name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Herbert Schulz
               affiliation:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                     address:
                        name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Oliver Hummel
               affiliation:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                     address:
                        name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Paola Martinelli
               affiliation:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                     address:
                        name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Norbert Hübner
               affiliation:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                     address:
                        name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lawrence W. Stanton
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Francisco X. Real
               affiliation:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                     address:
                        name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                        type:PostalAddress
                     type:Organization
                     name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
                     address:
                        name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Pierre-Yves Bourillot
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Pierre Savatier
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells
      description:Krüppel-like factors (Klf) 4 and 5 are two closely related members of the Klf family, known to play key roles in cell cycle regulation, somatic cell reprogramming and pluripotency. Here we focus on the functional divergence between Klf4 and Klf5 in the inhibition of mouse embryonic stem (ES) cell differentiation. Using microarrays and chromatin immunoprecipitation coupled to ultra-high-throughput DNA sequencing, we show that Klf4 negatively regulates the expression of endodermal markers in the undifferentiated ES cells, including transcription factors involved in the commitment of pluripotent stem cells to endoderm differentiation. Knockdown of Klf4 enhances differentiation towards visceral and definitive endoderm. In contrast, Klf5 negatively regulates the expression of mesodermal markers, some of which control commitment to the mesoderm lineage, and knockdown of Klf5 specifically enhances differentiation towards mesoderm. We conclude that Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in murine ES cells. The Krüppel-like factors Klf4 and Klf5 have wide roles in cell biology including the regulation of pluripotency. In this study, Aksoy et al. demonstrate that Klf4 preferentially blocks the expression of endodermal markers in embryonic stem cells, whereas Klf5 negatively regulates mesodermal factors.
      datePublished:2014-04-28T00:00:00Z
      dateModified:2014-04-28T00:00:00Z
      pageStart:1
      pageEnd:15
      sameAs:https://doi.org/10.1038/ncomms4719
      keywords:
         Cell signalling
         Embryogenesis
         Stem-cell differentiation
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Figa_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig5_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig6_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig7_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig8_HTML.jpg
      isPartOf:
         name:Nature Communications
         issn:
            2041-1723
         volumeNumber:5
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Irène Aksoy
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Vincent Giudice
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Edwige Delahaye
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Florence Wianny
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maxime Aubry
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Magali Mure
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jiaxuan Chen
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ralf Jauch
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
                  name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
                  address:
                     name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gireesh K. Bogu
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tobias Nolden
            affiliation:
                  name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                  address:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Heinz Himmelbauer
            affiliation:
                  name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                  address:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                     type:PostalAddress
                  type:Organization
                  name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
                  address:
                     name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                  address:
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael Xavier Doss
            affiliation:
                  name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                  address:
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
                  address:
                     name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Agapios Sachinidis
            affiliation:
                  name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
                  address:
                     name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Herbert Schulz
            affiliation:
                  name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                  address:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Oliver Hummel
            affiliation:
                  name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                  address:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Paola Martinelli
            affiliation:
                  name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                  address:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Norbert Hübner
            affiliation:
                  name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                  address:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lawrence W. Stanton
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Francisco X. Real
            affiliation:
                  name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                  address:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                     type:PostalAddress
                  type:Organization
                  name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
                  address:
                     name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Pierre-Yves Bourillot
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Pierre Savatier
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Communications
      issn:
         2041-1723
      volumeNumber:5
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
      address:
         name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
      address:
         name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
         type:PostalAddress
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
      address:
         name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
         type:PostalAddress
      name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
      address:
         name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
         type:PostalAddress
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
      address:
         name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
         type:PostalAddress
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
      address:
         name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
         type:PostalAddress
      name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
      address:
         name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
         type:PostalAddress
      name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
      address:
         name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
         type:PostalAddress
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
      address:
         name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
         type:PostalAddress
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
      address:
         name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
         type:PostalAddress
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
      address:
         name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
         type:PostalAddress
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
      address:
         name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
      address:
         name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
         type:PostalAddress
      name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
      address:
         name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Irène Aksoy
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Vincent Giudice
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Edwige Delahaye
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Florence Wianny
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Maxime Aubry
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Magali Mure
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Jiaxuan Chen
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Ralf Jauch
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
            name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
            address:
               name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
               type:PostalAddress
            type:Organization
      name:Gireesh K. Bogu
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Tobias Nolden
      affiliation:
            name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
            address:
               name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Heinz Himmelbauer
      affiliation:
            name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
            address:
               name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
               type:PostalAddress
            type:Organization
            name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
            address:
               name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
            address:
               name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Michael Xavier Doss
      affiliation:
            name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
            address:
               name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
            address:
               name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
               type:PostalAddress
            type:Organization
      name:Agapios Sachinidis
      affiliation:
            name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
            address:
               name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
               type:PostalAddress
            type:Organization
      name:Herbert Schulz
      affiliation:
            name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
            address:
               name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Oliver Hummel
      affiliation:
            name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
            address:
               name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Paola Martinelli
      affiliation:
            name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
            address:
               name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
               type:PostalAddress
            type:Organization
      name:Norbert Hübner
      affiliation:
            name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
            address:
               name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Lawrence W. Stanton
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Francisco X. Real
      affiliation:
            name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
            address:
               name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
               type:PostalAddress
            type:Organization
            name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
            address:
               name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Pierre-Yves Bourillot
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Pierre Savatier
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
      name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
      name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
      name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
      name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/NatureCommunications
• https://twitter.com/NatureComms

External Links {🔗}(174)

• How much revenue does http://www.dharmacon.com produce monthly?
• How much does http://code.google.com/p/bedtools/ rake in every month?
• How much does http://www.ebi.ac.uk/arrayexpress bring in each month?
• Earnings of http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE49848
• How much does https://doi.org/10.1016%2Fj.biocel.2007.07.018 earn?
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20transcription%20factors%3A%20a%20functional%20family&journal=Int.%20J.%20Biochem.%20Cell%20Biol.&doi=10.1016%2Fj.biocel.2007.07.018&volume=40&pages=1996-2001&publication_year=2008&author=Pearson%2CR&author=Fleetwood%2CJ&author=Eaton%2CS&author=Crossley%2CM&author=Bao%2CS?
• How much profit does https://doi.org/10.1038%2Fsj.cr.7290271 make?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factors%204%20and%205%3A%20the%20yin%20and%20yang%20regulators%20of%20cellular%20proliferation&journal=Cell.%20Res.&doi=10.1038%2Fsj.cr.7290271&volume=15&pages=92-96&publication_year=2005&author=Ghaleb%2CAM?
• What's the revenue for https://doi.org/10.1002%2Fbies.20581?
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=The%20diverse%20functions%20of%20Kr%C3%BCppel-like%20factors%204%20and%205%20in%20epithelial%20biology%20and%20pathobiology&journal=Bioessays&doi=10.1002%2Fbies.20581&volume=29&pages=549-557&publication_year=2007&author=McConnell%2CBB&author=Ghaleb%2CAM&author=Nandan%2CMO&author=Yang%2CVW?
• What are the earnings of https://doi.org/10.1093%2Fnar%2Fgkf400?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Opposing%20effects%20of%20Kruppel-like%20factor%204%20%28gut-enriched%20Kruppel-like%20factor%29%20and%20Kruppel-like%20factor%205%20%28intestinal-enriched%20Kruppel-like%20factor%29%20on%20the%20promoter%20of%20the%20Kruppel-like%20factor%204%20gene&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkf400&volume=30&pages=2736-2741&publication_year=2002&author=Dang%2CDT&author=Zhao%2CW&author=Mahatan%2CC%20S&author=Geiman%2CDE&author=Yang%2CVW generate?
• Discover the revenue of https://doi.org/10.1074%2Fjbc.M301902200
• What's the profit of http://scholar.google.com/scholar_lookup?&title=A%20transforming%20growth%20factor-beta%20control%20element%20required%20for%20SM%20alpha-actin%20expression%20in%20vivo%20also%20partially%20mediates%20GKLF-dependent%20transcriptional%20repression&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M301902200&volume=278&pages=48004-48011&publication_year=2003&author=Liu%2CY&author=Sinha%2CS&author=Owens%2CG?
• How much money does https://doi.org/10.1074%2Fjbc.M305804200 generate?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factors%20regulate%20the%20Lama1%20gene%20encoding%20the%20laminin%20alpha1%20chain&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M305804200&volume=279&pages=9103-9114&publication_year=2004&author=Piccinni%2CSA?
• Monthly income for https://doi.org/10.1074%2Fjbc.M307631200
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Requirement%20of%20Kruppel-like%20factor%204%20in%20preventing%20entry%20into%20mitosis%20following%20DNA%20damage&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M307631200&volume=279&pages=5035-5041&publication_year=2004&author=Yoon%2CHS&author=Yang%2CVW?
• Profit of https://doi.org/10.1074%2Fjbc.271.33.20009
• Find out how much http://scholar.google.com/scholar_lookup?&title=Identification%20and%20characterization%20of%20a%20gene%20encoding%20a%20gut-enriched%20Kruppel-like%20factor%20expressed%20during%20growth%20arrest&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.271.33.20009&volume=271&pages=20009-20017&publication_year=1996&author=Shields%2CJM&author=Christy%2CRJ&author=Yang%2CVW earns monthly
• What is the monthly revenue of https://doi.org/10.1016%2Fj.cell.2006.07.024?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Induction%20of%20pluripotent%20stem%20cells%20from%20mouse%20embryonic%20and%20adult%20fibroblast%20cultures%20by%20defined%20factors&journal=Cell&doi=10.1016%2Fj.cell.2006.07.024&volume=126&pages=663-676&publication_year=2006&author=Takahashi%2CK&author=Yamanaka%2CS make?
• How much revenue does https://doi.org/10.1002%2Fstem.110 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=Novel%20STAT3%20target%20genes%20exert%20distinct%20roles%20in%20the%20inhibition%20of%20mesoderm%20and%20endoderm%20differentiation%20in%20cooperation%20with%20Nanog&journal=Stem%20Cells&doi=10.1002%2Fstem.110&volume=27&pages=1760-1771&publication_year=2009&author=Bourillot%2CPY net monthly?
• Get to know https://doi.org/10.1371%2Fjournal.pone.0006804's earnings
• Profit of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2009PLoSO...4.6804S
• What's the income of http://scholar.google.com/scholar_lookup?&title=The%20FunGenES%20database%3A%20a%20genomics%20resource%20for%20mouse%20embryonic%20stem%20cell%20differentiation&journal=PLoS%20One&doi=10.1371%2Fjournal.pone.0006804&volume=4&publication_year=2009&author=Schulz%2CH?
• What's the income of https://doi.org/10.1242%2Fjcs.027599?
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=Klf5%20is%20involved%20in%20self-renewal%20of%20mouse%20embryonic%20stem%20cells&journal=J.%20Cell.%20Sci.&doi=10.1242%2Fjcs.027599&volume=121&pages=2629-2634&publication_year=2008&author=Parisi%2CS each month?
• How much does https://doi.org/10.1182%2Fblood-2004-07-2681 bring in each month?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Murine%20embryonic%20stem%20cell%20differentiation%20is%20promoted%20by%20SOCS-3%20and%20inhibited%20by%20the%20zinc%20finger%20transcription%20factor%20Klf4&journal=Blood&doi=10.1182%2Fblood-2004-07-2681&volume=105&pages=635-637&publication_year=2005&author=Li%2CY?
• Revenue of https://doi.org/10.1016%2Fj.stem.2008.09.003
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factor%205%20is%20essential%20for%20blastocyst%20development%20and%20the%20normal%20self-renewal%20of%20mouse%20ESCs&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2008.09.003&volume=3&pages=555-567&publication_year=2008&author=Ema%2CM
• How much does https://doi.org/10.1146%2Fannurev.cellbio.17.1.435 bring in each month?
• http://scholar.google.com/scholar_lookup?&title=Embryo-derived%20stem%20cells%3A%20of%20mice%20and%20men&journal=Annu.%20Rev.%20Cell.%20Dev.%20Biol.&doi=10.1146%2Fannurev.cellbio.17.1.435&volume=17&pages=435-462&publication_year=2001&author=Smith%2CAG income
• What's the revenue for https://doi.org/10.1038%2F11926?
• How profitable is http://scholar.google.com/scholar_lookup?&title=Klf4%20is%20a%20transcription%20factor%20required%20for%20establishing%20the%20barrier%20function%20of%20the%20skin&journal=Nat.%20Genet.&doi=10.1038%2F11926&volume=22&pages=356-360&publication_year=1999&author=Segre%2CJA&author=Bauer%2CC&author=Fuchs%2CE?
• Get to know what's the income of https://doi.org/10.1038%2Fncb1698
• Revenue of http://scholar.google.com/scholar_lookup?&title=A%20core%20Klf%20circuitry%20regulates%20self-renewal%20of%20embryonic%20stem%20cells&journal=Nat.%20Cell.%20Biol.&doi=10.1038%2Fncb1698&volume=10&pages=353-360&publication_year=2008&author=Jiang%2CJ
• How much revenue does https://doi.org/10.1016%2FS0092-8674%2803%2900392-1 generate?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Functional%20expression%20cloning%20of%20Nanog%2C%20a%20pluripotency%20sustaining%20factor%20in%20embryonic%20stem%20cells&journal=Cell&doi=10.1016%2FS0092-8674%2803%2900392-1&volume=113&pages=643-655&publication_year=2003&author=Chambers%2CI?
• How much does https://doi.org/10.1016%2FS0092-8674%2803%2900393-3 earn?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20homeoprotein%20Nanog%20is%20required%20for%20maintenance%20of%20pluripotency%20in%20mouse%20epiblast%20and%20ES%20cells&journal=Cell&doi=10.1016%2FS0092-8674%2803%2900393-3&volume=113&pages=631-642&publication_year=2003&author=Mitsui%2CK make?
• What is the earnings of https://doi.org/10.1016%2Fj.devcel.2006.02.020?
• http://scholar.google.com/scholar_lookup?&title=Early%20lineage%20segregation%20between%20epiblast%20and%20primitive%20endoderm%20in%20mouse%20blastocysts%20through%20the%20Grb2-MAPK%20pathway&journal=Dev.%20Cell&doi=10.1016%2Fj.devcel.2006.02.020&volume=10&pages=615-624&publication_year=2006&author=Chazaud%2CC&author=Yamanaka%2CY&author=Pawson%2CT&author=Rossant%2CJ's financial summary
• What's the income of https://doi.org/10.1016%2Fj.cell.2008.04.043?
• What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Integration%20of%20external%20signaling%20pathways%20with%20the%20core%20transcriptional%20network%20in%20embryonic%20stem%20cells&journal=Cell&doi=10.1016%2Fj.cell.2008.04.043&volume=133&pages=1106-1117&publication_year=2008&author=Chen%2CX?
• How much does https://link.springer.com/doi/10.1186/1741-7007-8-128 rake in every month?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Direct%20targets%20of%20Klf5%20transcription%20factor%20contribute%20to%20the%20maintenance%20of%20mouse%20embryonic%20stem%20cell%20undifferentiated%20state&journal=BMC%20Biol.&doi=10.1186%2F1741-7007-8-128&volume=8&publication_year=2010&author=Parisi%2CS produce monthly?
• Income figures for https://link.springer.com/doi/10.1186/1741-7007-8-125
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20transcription%20factors%20and%20control%20of%20pluripotency&journal=BMC%20Biol.&doi=10.1186%2F1741-7007-8-125&volume=8&publication_year=2010&author=Bourillot%2CPY&author=Savatier%2CP have monthly?
• How much revenue does https://doi.org/10.1038%2Fnrc1780 generate?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=KLF4%2C%20p21%20and%20context-dependent%20opposing%20forces%20in%20cancer&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc1780&volume=6&pages=11-23&publication_year=2006&author=Rowland%2CBD&author=Peeper%2CDS generate?
• How much profit does https://doi.org/10.1074%2Fjbc.M403724200 generate?
• How much income is http://scholar.google.com/scholar_lookup?&title=SOX7%20and%20SOX17%20regulate%20the%20parietal%20endoderm-specific%20enhancer%20activity%20of%20mouse%20laminin%20alpha1%20gene&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M403724200&volume=279&pages=38055-38061&publication_year=2004&author=Niimi%2CT&author=Hayashi%2CY&author=Futaki%2CS&author=Sekiguchi%2CK earning monthly?
• Discover the revenue of https://doi.org/10.1128%2FMCB.24.23.10492-10503.2004
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=Sox7%20plays%20crucial%20roles%20in%20parietal%20endoderm%20differentiation%20in%20F9%20embryonal%20carcinoma%20cells%20through%20regulating%20Gata-4%20and%20Gata-6%20expression&journal=Mol.%20Cell%20Biol.&doi=10.1128%2FMCB.24.23.10492-10503.2004&volume=24&pages=10492-10503&publication_year=2004&author=Futaki%2CS&author=Hayashi%2CY&author=Emoto%2CT&author=Weber%2CCN&author=Sekiguchi%2CK?
• How much profit does https://doi.org/10.1038%2Fnbt1167 make?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Induction%20and%20monitoring%20of%20definitive%20and%20visceral%20endoderm%20differentiation%20of%20mouse%20ES%20cells&journal=Nat.%20Biotechnol.&doi=10.1038%2Fnbt1167&volume=23&pages=1542-1550&publication_year=2005&author=Yasunaga%2CM
• Profit of https://doi.org/10.1634%2Fstemcells.2005-0344
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Crucial%20transcription%20factors%20in%20endoderm%20and%20embryonic%20gut%20development%20are%20expressed%20in%20gut-like%20structures%20from%20mouse%20ES%20cells&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2005-0344&volume=24&pages=624-630&publication_year=2006&author=Matsuura%2CR?
• What is the earnings of https://doi.org/10.1111%2Fj.1440-169X.2008.01056.x?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Sox17%20facilitates%20the%20differentiation%20of%20mouse%20embryonic%20stem%20cells%20into%20primitive%20and%20definitive%20endoderm%20in%20vitro&journal=Dev.%20Growth%20Differ.&doi=10.1111%2Fj.1440-169X.2008.01056.x&volume=50&pages=585-593&publication_year=2008&author=Qu%2CXB&author=Pan%2CJ&author=Zhang%2CC&author=Huang%2CSY
• Monthly income for https://doi.org/10.1016%2Fj.stem.2008.06.018
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Establishment%20of%20endoderm%20progenitors%20by%20SOX%20transcription%20factor%20expression%20in%20human%20embryonic%20stem%20cells&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2008.06.018&volume=3&pages=182-195&publication_year=2008&author=Seguin%2CCA&author=Draper%2CJS&author=Nagy%2CA&author=Rossant%2CJ?
• What's the monthly income of https://doi.org/10.1101%2Fgad.1833510?
• How much money does http://scholar.google.com/scholar_lookup?&title=Sox17%20promotes%20differentiation%20in%20mouse%20embryonic%20stem%20cells%20by%20directly%20regulating%20extraembryonic%20gene%20expression%20and%20indirectly%20antagonizing%20self-renewal&journal=Genes%20Dev.&doi=10.1101%2Fgad.1833510&volume=24&pages=312-326&publication_year=2010&author=Niakan%2CKK make?
• What's https://doi.org/10.1038%2F343657a0's gross income?
• How profitable is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1990Natur.343..657W?
• How much does http://scholar.google.com/scholar_lookup?&title=Expression%20pattern%20of%20the%20mouse%20T%20gene%20and%20its%20role%20in%20mesoderm%20formation&journal=Nature&doi=10.1038%2F343657a0&volume=343&pages=657-659&publication_year=1990&author=Wilkinson%2CDG&author=Bhatt%2CS&author=Herrmann%2CBG earn?
• Get to know what's the income of https://doi.org/10.1074%2Fjbc.R100043200
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factors%3A%20three%20fingers%20in%20many%20pies&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.R100043200&volume=276&pages=34355-34358&publication_year=2001&author=Bieker%2CJJ
• How much does https://doi.org/10.1038%2Fnature11247 bring in each month?
• What's the profit of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2012Natur.489...57T?
• Income figures for http://scholar.google.com/scholar_lookup?&title=An%20integrated%20encyclopedia%20of%20DNA%20elements%20in%20the%20human%20genome&journal=Nature&doi=10.1038%2Fnature11247&volume=489&pages=57-74&publication_year=2012&author=Dunham%2CI
• What's the financial intake of https://doi.org/10.1111%2Fj.1365-2443.2010.01390.x?
• Profit of http://scholar.google.com/scholar_lookup?&title=Global%20transcriptomic%20analysis%20of%20murine%20embryonic%20stem%20cell-derived%20brachyury%20%28T%29%20cells&journal=Genes%20Cells&doi=10.1111%2Fj.1365-2443.2010.01390.x&volume=15&pages=209-228&publication_year=2010&author=Doss%2CMX
• How much profit does https://doi.org/10.1159%2F000329864 generate?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Induction%20and%20selection%20of%20Sox17-expressing%20endoderm%20cells%20generated%20from%20murine%20embryonic%20stem%20cells&journal=Cells%20Tissues%20Organs&doi=10.1159%2F000329864&volume=195&pages=507-523&publication_year=2012&author=Schroeder%2CIS?
• How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11973269 net monthly?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Depletion%20of%20definitive%20gut%20endoderm%20in%20Sox17-null%20mutant%20mice&journal=Development&volume=129&pages=2367-2379&publication_year=2002&author=Kanai-Azuma%2CM?
• How much income does https://doi.org/10.1242%2Fdev.02005 have?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Characterization%20of%20mesendoderm%3A%20a%20diverging%20point%20of%20the%20definitive%20endoderm%20and%20mesoderm%20in%20embryonic%20stem%20cell%20differentiation%20culture&journal=Development&doi=10.1242%2Fdev.02005&volume=132&pages=4363-4374&publication_year=2005&author=Tada%2CS
• How much income is https://doi.org/10.1634%2Fstemcells.2005-0256 earning monthly?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=In%20vitro%20modeling%20of%20paraxial%20and%20lateral%20mesoderm%20differentiation%20reveals%20early%20reversibility&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2005-0256&volume=24&pages=575-586&publication_year=2006&author=Sakurai%2CH
• What's the monthly income of https://doi.org/10.1101%2Fgad.968802?
• Profit of http://scholar.google.com/scholar_lookup?&title=Differentiation%20of%20embryonic%20stem%20cells%20is%20induced%20by%20GATA%20factors&journal=Genes%20Dev.&doi=10.1101%2Fgad.968802&volume=16&pages=784-789&publication_year=2002&author=Fujikura%2CJ
• How much does https://link.springer.com/doi/10.1186/1471-213X-7-80 rake in every month?
• How much does http://scholar.google.com/scholar_lookup?&title=Extra-embryonic%20endoderm%20cells%20derived%20from%20ES%20cells%20induced%20by%20GATA%20factors%20acquire%20the%20character%20of%20XEN%20cells&journal=BMC%20Dev.%20Biol.&doi=10.1186%2F1471-213X-7-80&volume=7&publication_year=2007&author=Shimosato%2CD&author=Shiki%2CM&author=Niwa%2CH bring in each month?
• How much revenue does https://doi.org/10.1038%2F86912 produce monthly?
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=The%20amnionless%20gene%2C%20essential%20for%20mouse%20gastrulation%2C%20encodes%20a%20visceral-endoderm-specific%20protein%20with%20an%20extracellular%20cysteine-rich%20domain&journal=Nat.%20Genet.&doi=10.1038%2F86912&volume=27&pages=412-416&publication_year=2001&author=Kalantry%2CS is on a monthly basis
• How much income does https://doi.org/10.1006%2Fdbio.2002.0810 have?
• Check the income stats for http://scholar.google.com/scholar_lookup?&title=Disabled-2%20is%20essential%20for%20endodermal%20cell%20positioning%20and%20structure%20formation%20during%20mouse%20embryogenesis&journal=Dev.%20Biol.&doi=10.1006%2Fdbio.2002.0810&volume=251&pages=27-44&publication_year=2002&author=Yang%2CDH
• How much does https://doi.org/10.1182%2Fblood-2005-10-4120 bring in each month?
• How much does http://scholar.google.com/scholar_lookup?&title=Acceleration%20of%20mesoderm%20development%20and%20expansion%20of%20hematopoietic%20progenitors%20in%20differentiating%20ES%20cells%20by%20the%20mouse%20Mix-like%20homeodomain%20transcription%20factor&journal=Blood&doi=10.1182%2Fblood-2005-10-4120&volume=107&pages=3122-3130&publication_year=2006&author=Willey%2CS earn?
• What's the monthly income of https://doi.org/10.1242%2Fdev.054775?
• How much income does http://scholar.google.com/scholar_lookup?&title=Klf5%20regulates%20lineage%20formation%20in%20the%20pre-implantation%20mouse%20embryo&journal=Development&doi=10.1242%2Fdev.054775&volume=137&pages=3953-3963&publication_year=2010&author=Lin%2CSC&author=Wani%2CMA&author=Whitsett%2CJ%20A&author=Wells%2CJM have?
• What are the total earnings of https://doi.org/10.1634%2Fstemcells.2007-0953?
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Derivation%20and%20cloning%20of%20a%20novel%20Rhesus%20ES%20cell%20line%20stably%20expressing%20tau-GFP&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2007-0953&volume=26&pages=1444-1453&publication_year=2008&author=Wianny%2CF?
• What's the total monthly financial gain of https://doi.org/10.1006%2Fdbio.1999.9544?
• Revenue of http://scholar.google.com/scholar_lookup?&title=Direct%20activation%20of%20a%20GATA6%20cardiac%20enhancer%20by%20Nkx2.5%3A%20evidence%20for%20a%20reinforcing%20regulatory%20network%20of%20Nkx2.5%20and%20GATA%20transcription%20factors%20in%20the%20developing%20heart&journal=Dev.%20Biol.&doi=10.1006%2Fdbio.1999.9544&volume=217&pages=301-309&publication_year=2000&author=Molkentin%2CJD
• Income figures for https://doi.org/10.1016%2Fj.scr.2012.10.004
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=A%20short%20G1%20phase%20is%20an%20intrinsic%20determinant%20of%20naive%20embryonic%20stem%20cell%20pluripotency&journal=Stem%20Cell%20Res.&doi=10.1016%2Fj.scr.2012.10.004&volume=10&pages=118-131&publication_year=2013&author=Coronado%2CD is on a monthly basis
• How much income is https://doi.org/10.1002%2F%28SICI%291097-0215%2819980302%2975%3A5%3C767%3A%3AAID-IJC17%3E3.0.CO%3B2-3 earning monthly?
• http://scholar.google.com/scholar_lookup?&title=Gastric%20M1%20mucin%2C%20an%20early%20oncofetal%20marker%20of%20colon%20carcinogenesis%2C%20is%20encoded%20by%20the%20MUC5AC%20gene&journal=Int.%20J.%20Cancer&doi=10.1002%2F%28SICI%291097-0215%2819980302%2975%3A5%3C767%3A%3AAID-IJC17%3E3.0.CO%3B2-3&volume=75&pages=767-773&publication_year=1998&author=Bara%2CJ's revenue stream
• Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=4187091
• What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232189?
• How much profit is http://scholar.google.com/scholar_lookup?&title=The%20in%20vivo%20staining%20of%20bone%20with%20alizarin%20red%20S&journal=J.%20Anat.&volume=105&pages=533-545&publication_year=1969&author=Vilmann%2CH making per month?
• How much profit does https://doi.org/10.1093%2Fbiostatistics%2F4.2.249 generate?
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Exploration%2C%20normalization%2C%20and%20summaries%20of%20high%20density%20oligonucleotide%20array%20probe%20level%20data&journal=Biostatistics&doi=10.1093%2Fbiostatistics%2F4.2.249&volume=4&pages=249-264&publication_year=2003&author=Irizarry%2CRA?
• What's the monthly income of https://doi.org/10.1073%2Fpnas.95.25.14863?
• What's the revenue for http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998PNAS...9514863E?
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Cluster%20analysis%20and%20display%20of%20genome-wide%20expression%20patterns&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.95.25.14863&volume=95&pages=14863-14868&publication_year=1998&author=Eisen%2CMB&author=Spellman%2CPT&author=Brown%2CPO&author=Botstein%2CD?
• What's the income of https://doi.org/10.1038%2Femboj.2013.31?
• How much does http://scholar.google.com/scholar_lookup?&title=Oct4%20switches%20partnering%20from%20Sox2%20to%20Sox17%20to%20reinterpret%20the%20enhancer%20code%20and%20specify%20endoderm&journal=EMBO%20J.&doi=10.1038%2Femboj.2013.31&volume=32&pages=938-953&publication_year=2013&author=Aksoy%2CI generate monthly?
• How much revenue does https://link.springer.com/doi/10.1186/gb-2008-9-9-r137 produce monthly?
• What's http://scholar.google.com/scholar_lookup?&title=Model-based%20analysis%20of%20ChIP-Seq%20%28MACS%29&journal=Genome%20Biol.&doi=10.1186%2Fgb-2008-9-9-r137&volume=9&publication_year=2008&author=Zhang%2CY's gross income?
• What is the monthly revenue of https://citation-needed.springer.com/v2/references/10.1038/ncomms4719?format=refman&flavour=references?
• http://www.a-star.edu.sg's total income per month
• What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ir%C3%A8ne%20Aksoy?
• Check the income stats for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ir%C3%A8ne%20Aksoy%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Vincent%20Giudice's earnings
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Vincent%20Giudice%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Edwige%20Delahaye
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Edwige%20Delahaye%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Florence%20Wianny's financial summary
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Florence%20Wianny%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Maxime%20Aubry?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Maxime%20Aubry%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Magali%20Mure
• Find out how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Magali%20Mure%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earns monthly
• What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jiaxuan%20Chen?
• What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jiaxuan%20Chen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Get to know https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ralf%20Jauch's earnings
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ralf%20Jauch%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gireesh%20K.%20Bogu net monthly?
• What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gireesh%20K.%20Bogu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Tobias%20Nolden's revenue stream
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tobias%20Nolden%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Heinz%20Himmelbauer
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Heinz%20Himmelbauer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20Xavier%20Doss's financial summary
• How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20Xavier%20Doss%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Agapios%20Sachinidis?
• How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Agapios%20Sachinidis%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Herbert%20Schulz?
• What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Herbert%20Schulz%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Oliver%20Hummel?
• What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Oliver%20Hummel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
• What's the revenue for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Paola%20Martinelli?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Paola%20Martinelli%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in?
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Norbert%20H%C3%BCbner?
• What is the monthly revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Norbert%20H%C3%BCbner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lawrence%20W.%20Stanton make?
• How much revenue does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lawrence%20W.%20Stanton%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in?
• Learn how profitable https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Francisco%20X.%20Real is on a monthly basis
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Francisco%20X.%20Real%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pierre-Yves%20Bourillot
• What's https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pierre-Yves%20Bourillot%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's gross income?
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pierre%20Savatier produce monthly?
• Income figures for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pierre%20Savatier%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's https://static-content.springer.com/esm/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_BFncomms4719_MOESM123_ESM.pdf's gross income?
• Get to know what's the income of https://s100.copyright.com/AppDispatchServlet?title=Klf4%20and%20Klf5%20differentially%20inhibit%20mesoderm%20and%20endoderm%20differentiation%20in%20embryonic%20stem%20cells&author=Ir%C3%A8ne%20Aksoy%20et%20al&contentID=10.1038%2Fncomms4719©right=Springer%20Nature%20Limited&publication=2041-1723&publicationDate=2014-04-28&publisherName=SpringerNature&orderBeanReset=true
• How much money does https://crossmark.crossref.org/dialog/?doi=10.1038/ncomms4719 generate?
• How much does https://citation-needed.springer.com/v2/references/10.1038/ncomms4719?format=refman&flavour=citation generate monthly?
• Get to know https://doi.org/10.1038/s41467-021-26125-x's earnings
• How profitable is https://doi.org/10.1038/s41467-021-24035-6?
• https://doi.org/10.1038/s41598-020-76951-0's total income per month
• Explore the financials of https://doi.org/10.1007/s11626-019-00341-8
• Revenue of https://doi.org/10.1038/s41467-017-02786-5
• How much does https://www.protocols.io/ pull in monthly?
• How profitable is https://www.natureindex.com/?
• What's the monthly income of http://www.naturechina.com?
• How much does https://www.natureasia.com/ja-jp pull in monthly?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref