We are analyzing https://link.springer.com/article/10.1186/1741-7007-8-125.

Title:
Krüppel-like transcription factors and control of pluripotency | BMC Biology
Description:
Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency. See research article http://www.biomedcentral.com/1741-7007/8/128
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Keywords {🔍}

klf, pluripotency, article, stem, differentiation, cells, factors, cell, selfrenewal, transcription, embryonic, pubmed, mouse, genes, esc, targets, google, scholar, expression, escs, state, network, savatier, factor, core, data, bmc, bourillot, klfs, oct, nanog, cas, research, control, parisi, lif, undifferentiated, privacy, cookies, access, pierre, role, colleagues, inactivation, maintenance, sox, circuitry, regulated, publish, search,

Topics {✒️}

leukemia inhibitory factor extraembryonic endoderm molecular circuitry essential cell stem cell article download pdf wild-type escs propagated embryonic stem cells cell cycle regulation molecular circuitry fully undifferentiated state pierre savatier research article http klf-rescued cells suggests privacy choices/manage cookies mouse es cells induced pluripotent stem klf2/klf4/klf5 triple knockdown metastable state characterized brain research institute article bourillot explored klf5-specific targets pluripotent mouse escs regulation makes klf4 transcription factors implicated european economic area undifferentiated state core pluripotency network nat cell biol authors’ original file klf4/klf5-specific targets maintain es cells université lyon 1 bmc biology klf4-specific target main content log cyclin-dependent kinases reprogramming somatic cells massive differentiation observed endoderm differentiation klf member regulates conditions privacy policy esc differentiation induced klf5 regulates pluripotency produce esc lines delays differentiation induced oct4/sox2/nanog network connects extrinsic regulators genes compromises pluripotency stem cells matching microarray data

Schema {🗺️}

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         description:Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency. See research article http://www.biomedcentral.com/1741-7007/8/128
         datePublished:2010-09-27T00:00:00Z
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         Mouse Embryonic Stem Cell
         Undifferentiated State
         Extraembryonic Endoderm
         Molecular Circuitry
         Life Sciences
         general
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      name:Université de Lyon, Lyon, France

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