NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Photography

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,616 monthly online from display advertisements.

Keywords {🔍}

klf, cells, differentiation, expression, klfkd, endoderm, article, control, cell, fig, google, scholar, genes, mesoderm, markers, knockdown, cas, sox, gata, stem, esgscgfpsoxhucdklfkd, mouse, definitive, klfoe, clones, mixl, embryonic, factors, endodermal, visceral, mesodermal, gene, performed, supplementary, increased, analysis, results, observed, teratomas, nature, gfp, fold, expressing, level, data, induced, day, showed, promoter, factor,

Topics {✒️}

nature portfolio permissions reprints privacy policy fluorescein-anti-mouse e-cadherin mab es-gscgfpsox17hucd25-klf5-kd clones exhibited advertising es-gscgfpsox17hucd25-klf4-kd clones exhibited ultra-high-throughput dna sequencing es-gscgfpsox17hucd25-klf4-kd cells exhibited es-gscgfpsox17hucd25-klf5-kd clones showed es-gscgfpsox17hucd25-klf4-kd clones showed south china institute apc-anti-human cd25 mab lif-deprived serum-free medium brain research institute apc-anti-mouse flk1 mab social media rnaeasy kits sox17-dsred-klf5-kd es cells pierre-yves bourillot michael xavier doss resulting es-gscgfpsox17hucd25-klf4-kd nature 343 nature 489 nature es-gscgfpsox17hucd25-klf5-kd clones es-gscgfpsox17hucd25-klf4-kd cells apc-anti-mouse cd140a evolutionarily conserved zinc-finger produce siv-derived lentivectors klf5-kd cells-derived teratomas context-dependent opposing forces klf4-kd cells-derived teratomas full access collagen iv-coated dishes klf5-kd2 cells-derived teratomas accession numbers e-mtab-1838 pgae-cag-egfp-wpre46 research grants generated es-gscgfpsox17hucd25 subclones quantitative real-time pcr embryo-derived stem cells extracellular cysteine-rich domain es-gscgfpsox17hucd25-klf5-kd real-time pcr analysis identify mucin-expressing epithelium es-gscgfpsox17hucd25-klf4-kd pre-implantation mouse embryo klf5-kd clones exhibited pgae-cag-klf5-wpre

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells
         description:Krüppel-like factors (Klf) 4 and 5 are two closely related members of the Klf family, known to play key roles in cell cycle regulation, somatic cell reprogramming and pluripotency. Here we focus on the functional divergence between Klf4 and Klf5 in the inhibition of mouse embryonic stem (ES) cell differentiation. Using microarrays and chromatin immunoprecipitation coupled to ultra-high-throughput DNA sequencing, we show that Klf4 negatively regulates the expression of endodermal markers in the undifferentiated ES cells, including transcription factors involved in the commitment of pluripotent stem cells to endoderm differentiation. Knockdown of Klf4 enhances differentiation towards visceral and definitive endoderm. In contrast, Klf5 negatively regulates the expression of mesodermal markers, some of which control commitment to the mesoderm lineage, and knockdown of Klf5 specifically enhances differentiation towards mesoderm. We conclude that Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in murine ES cells. The Krüppel-like factors Klf4 and Klf5 have wide roles in cell biology including the regulation of pluripotency. In this study, Aksoy et al. demonstrate that Klf4 preferentially blocks the expression of endodermal markers in embryonic stem cells, whereas Klf5 negatively regulates mesodermal factors.
         datePublished:2014-04-28T00:00:00Z
         dateModified:2014-04-28T00:00:00Z
         pageStart:1
         pageEnd:15
         sameAs:https://doi.org/10.1038/ncomms4719
         keywords:
            Cell signalling
            Embryogenesis
            Stem-cell differentiation
            Science
            Humanities and Social Sciences
            multidisciplinary
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Figa_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig5_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig6_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig7_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig8_HTML.jpg
         isPartOf:
            name:Nature Communications
            issn:
               2041-1723
            volumeNumber:5
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Irène Aksoy
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Vincent Giudice
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Edwige Delahaye
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Florence Wianny
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Maxime Aubry
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Magali Mure
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jiaxuan Chen
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ralf Jauch
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
                     name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
                     address:
                        name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gireesh K. Bogu
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tobias Nolden
               affiliation:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                     address:
                        name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Heinz Himmelbauer
               affiliation:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                     address:
                        name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                        type:PostalAddress
                     type:Organization
                     name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
                     address:
                        name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                     address:
                        name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael Xavier Doss
               affiliation:
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                     address:
                        name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
                     address:
                        name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Agapios Sachinidis
               affiliation:
                     name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
                     address:
                        name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Herbert Schulz
               affiliation:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                     address:
                        name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Oliver Hummel
               affiliation:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                     address:
                        name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Paola Martinelli
               affiliation:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                     address:
                        name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Norbert Hübner
               affiliation:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                     address:
                        name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lawrence W. Stanton
               affiliation:
                     name:Genome Institute of Singapore, 60 Biopolis street
                     address:
                        name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Francisco X. Real
               affiliation:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                     address:
                        name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                        type:PostalAddress
                     type:Organization
                     name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
                     address:
                        name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Pierre-Yves Bourillot
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Pierre Savatier
               affiliation:
                     name:Inserm, U846, 18 Avenue Doyen Lepine
                     address:
                        name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Stem Cell and Brain Research Institute
                     address:
                        name:Stem Cell and Brain Research Institute, Bron, France
                        type:PostalAddress
                     type:Organization
                     name:Université de Lyon, Université Lyon 1
                     address:
                        name:Université de Lyon, Université Lyon 1, Lyon, France
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells
      description:Krüppel-like factors (Klf) 4 and 5 are two closely related members of the Klf family, known to play key roles in cell cycle regulation, somatic cell reprogramming and pluripotency. Here we focus on the functional divergence between Klf4 and Klf5 in the inhibition of mouse embryonic stem (ES) cell differentiation. Using microarrays and chromatin immunoprecipitation coupled to ultra-high-throughput DNA sequencing, we show that Klf4 negatively regulates the expression of endodermal markers in the undifferentiated ES cells, including transcription factors involved in the commitment of pluripotent stem cells to endoderm differentiation. Knockdown of Klf4 enhances differentiation towards visceral and definitive endoderm. In contrast, Klf5 negatively regulates the expression of mesodermal markers, some of which control commitment to the mesoderm lineage, and knockdown of Klf5 specifically enhances differentiation towards mesoderm. We conclude that Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in murine ES cells. The Krüppel-like factors Klf4 and Klf5 have wide roles in cell biology including the regulation of pluripotency. In this study, Aksoy et al. demonstrate that Klf4 preferentially blocks the expression of endodermal markers in embryonic stem cells, whereas Klf5 negatively regulates mesodermal factors.
      datePublished:2014-04-28T00:00:00Z
      dateModified:2014-04-28T00:00:00Z
      pageStart:1
      pageEnd:15
      sameAs:https://doi.org/10.1038/ncomms4719
      keywords:
         Cell signalling
         Embryogenesis
         Stem-cell differentiation
         Science
         Humanities and Social Sciences
         multidisciplinary
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Figa_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig5_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig6_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig7_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_Article_BFncomms4719_Fig8_HTML.jpg
      isPartOf:
         name:Nature Communications
         issn:
            2041-1723
         volumeNumber:5
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Irène Aksoy
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Vincent Giudice
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Edwige Delahaye
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Florence Wianny
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Maxime Aubry
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Magali Mure
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jiaxuan Chen
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ralf Jauch
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
                  name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
                  address:
                     name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gireesh K. Bogu
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tobias Nolden
            affiliation:
                  name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                  address:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Heinz Himmelbauer
            affiliation:
                  name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
                  address:
                     name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
                     type:PostalAddress
                  type:Organization
                  name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
                  address:
                     name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                  address:
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael Xavier Doss
            affiliation:
                  name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
                  address:
                     name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
                  address:
                     name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Agapios Sachinidis
            affiliation:
                  name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
                  address:
                     name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Herbert Schulz
            affiliation:
                  name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                  address:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Oliver Hummel
            affiliation:
                  name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                  address:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Paola Martinelli
            affiliation:
                  name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                  address:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Norbert Hübner
            affiliation:
                  name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
                  address:
                     name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lawrence W. Stanton
            affiliation:
                  name:Genome Institute of Singapore, 60 Biopolis street
                  address:
                     name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Francisco X. Real
            affiliation:
                  name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
                  address:
                     name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
                     type:PostalAddress
                  type:Organization
                  name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
                  address:
                     name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Pierre-Yves Bourillot
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Pierre Savatier
            affiliation:
                  name:Inserm, U846, 18 Avenue Doyen Lepine
                  address:
                     name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Stem Cell and Brain Research Institute
                  address:
                     name:Stem Cell and Brain Research Institute, Bron, France
                     type:PostalAddress
                  type:Organization
                  name:Université de Lyon, Université Lyon 1
                  address:
                     name:Université de Lyon, Université Lyon 1, Lyon, France
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Communications
      issn:
         2041-1723
      volumeNumber:5
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
      address:
         name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
      address:
         name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
         type:PostalAddress
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
      address:
         name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
         type:PostalAddress
      name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
      address:
         name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
         type:PostalAddress
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
      address:
         name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
         type:PostalAddress
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
      address:
         name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
         type:PostalAddress
      name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
      address:
         name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
         type:PostalAddress
      name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
      address:
         name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
         type:PostalAddress
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
      address:
         name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
         type:PostalAddress
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
      address:
         name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
         type:PostalAddress
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
      address:
         name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
         type:PostalAddress
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
      address:
         name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
         type:PostalAddress
      name:Genome Institute of Singapore, 60 Biopolis street
      address:
         name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
         type:PostalAddress
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
      address:
         name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
         type:PostalAddress
      name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
      address:
         name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
      name:Inserm, U846, 18 Avenue Doyen Lepine
      address:
         name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
         type:PostalAddress
      name:Stem Cell and Brain Research Institute
      address:
         name:Stem Cell and Brain Research Institute, Bron, France
         type:PostalAddress
      name:Université de Lyon, Université Lyon 1
      address:
         name:Université de Lyon, Université Lyon 1, Lyon, France
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Irène Aksoy
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Vincent Giudice
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Edwige Delahaye
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Florence Wianny
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Maxime Aubry
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Magali Mure
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      name:Jiaxuan Chen
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Ralf Jauch
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
            name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
            address:
               name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
               type:PostalAddress
            type:Organization
      name:Gireesh K. Bogu
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Tobias Nolden
      affiliation:
            name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
            address:
               name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Heinz Himmelbauer
      affiliation:
            name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73
            address:
               name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
               type:PostalAddress
            type:Organization
            name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88
            address:
               name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
            address:
               name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Michael Xavier Doss
      affiliation:
            name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88
            address:
               name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA
            address:
               name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
               type:PostalAddress
            type:Organization
      name:Agapios Sachinidis
      affiliation:
            name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39
            address:
               name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
               type:PostalAddress
            type:Organization
      name:Herbert Schulz
      affiliation:
            name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
            address:
               name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Oliver Hummel
      affiliation:
            name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
            address:
               name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Paola Martinelli
      affiliation:
            name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
            address:
               name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
               type:PostalAddress
            type:Organization
      name:Norbert Hübner
      affiliation:
            name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10
            address:
               name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
               type:PostalAddress
            type:Organization
      name:Lawrence W. Stanton
      affiliation:
            name:Genome Institute of Singapore, 60 Biopolis street
            address:
               name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
               type:PostalAddress
            type:Organization
      name:Francisco X. Real
      affiliation:
            name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3
            address:
               name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
               type:PostalAddress
            type:Organization
            name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra
            address:
               name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Pierre-Yves Bourillot
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Pierre Savatier
      affiliation:
            name:Inserm, U846, 18 Avenue Doyen Lepine
            address:
               name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
               type:PostalAddress
            type:Organization
            name:Stem Cell and Brain Research Institute
            address:
               name:Stem Cell and Brain Research Institute, Bron, France
               type:PostalAddress
            type:Organization
            name:Université de Lyon, Université Lyon 1
            address:
               name:Université de Lyon, Université Lyon 1, Lyon, France
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Genome Regulation Laboratory, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
      name:Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, Berlin, Germany
      name:Center for Genomic Regulation (CRG), C. Dr. Aiguader 88, Barcelona, Spain
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
      name:Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, Barcelona, Spain
      name:Present address: Stem Cell Center, Masonic Medical Research Laboratory, Utica, New York-13501, USA,
      name:Center of Physiology and Pathophysiology, Institute of Neurophysiology, Robert-Koch-Strasse. 39, Cologne, Germany
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
      name:Max Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, Berlin, Germany
      name:Genome Institute of Singapore, 60 Biopolis street, Singapore, Singapore
      name:Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain
      name:Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
      name:Inserm, U846, 18 Avenue Doyen Lepine, Bron, France
      name:Stem Cell and Brain Research Institute, Bron, France
      name:Université de Lyon, Université Lyon 1, Lyon, France
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

• https://www.facebook.com/NatureCommunications
• https://twitter.com/NatureComms

External Links {🔗}(174)

• How much profit does http://www.dharmacon.com generate?
• Find out how much http://code.google.com/p/bedtools/ earns monthly
• What's the financial outcome of http://www.ebi.ac.uk/arrayexpress?
• How much income does http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE49848 have?
• How much revenue does https://doi.org/10.1016%2Fj.biocel.2007.07.018 bring in?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20transcription%20factors%3A%20a%20functional%20family&journal=Int.%20J.%20Biochem.%20Cell%20Biol.&doi=10.1016%2Fj.biocel.2007.07.018&volume=40&pages=1996-2001&publication_year=2008&author=Pearson%2CR&author=Fleetwood%2CJ&author=Eaton%2CS&author=Crossley%2CM&author=Bao%2CS generate?
• Learn about the earnings of https://doi.org/10.1038%2Fsj.cr.7290271
• http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factors%204%20and%205%3A%20the%20yin%20and%20yang%20regulators%20of%20cellular%20proliferation&journal=Cell.%20Res.&doi=10.1038%2Fsj.cr.7290271&volume=15&pages=92-96&publication_year=2005&author=Ghaleb%2CAM's total income per month
• What's the income of https://doi.org/10.1002%2Fbies.20581?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20diverse%20functions%20of%20Kr%C3%BCppel-like%20factors%204%20and%205%20in%20epithelial%20biology%20and%20pathobiology&journal=Bioessays&doi=10.1002%2Fbies.20581&volume=29&pages=549-557&publication_year=2007&author=McConnell%2CBB&author=Ghaleb%2CAM&author=Nandan%2CMO&author=Yang%2CVW bring in each month?
• What is the earnings of https://doi.org/10.1093%2Fnar%2Fgkf400?
• Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Opposing%20effects%20of%20Kruppel-like%20factor%204%20%28gut-enriched%20Kruppel-like%20factor%29%20and%20Kruppel-like%20factor%205%20%28intestinal-enriched%20Kruppel-like%20factor%29%20on%20the%20promoter%20of%20the%20Kruppel-like%20factor%204%20gene&journal=Nucleic%20Acids%20Res.&doi=10.1093%2Fnar%2Fgkf400&volume=30&pages=2736-2741&publication_year=2002&author=Dang%2CDT&author=Zhao%2CW&author=Mahatan%2CC%20S&author=Geiman%2CDE&author=Yang%2CVW
• What's the income of https://doi.org/10.1074%2Fjbc.M301902200?
• Get to know http://scholar.google.com/scholar_lookup?&title=A%20transforming%20growth%20factor-beta%20control%20element%20required%20for%20SM%20alpha-actin%20expression%20in%20vivo%20also%20partially%20mediates%20GKLF-dependent%20transcriptional%20repression&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M301902200&volume=278&pages=48004-48011&publication_year=2003&author=Liu%2CY&author=Sinha%2CS&author=Owens%2CG's earnings
• Learn how profitable https://doi.org/10.1074%2Fjbc.M305804200 is on a monthly basis
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factors%20regulate%20the%20Lama1%20gene%20encoding%20the%20laminin%20alpha1%20chain&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M305804200&volume=279&pages=9103-9114&publication_year=2004&author=Piccinni%2CSA?
• How much money does https://doi.org/10.1074%2Fjbc.M307631200 make?
• What's the income generated by http://scholar.google.com/scholar_lookup?&title=Requirement%20of%20Kruppel-like%20factor%204%20in%20preventing%20entry%20into%20mitosis%20following%20DNA%20damage&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M307631200&volume=279&pages=5035-5041&publication_year=2004&author=Yoon%2CHS&author=Yang%2CVW each month?
• How much profit is https://doi.org/10.1074%2Fjbc.271.33.20009 making per month?
• http://scholar.google.com/scholar_lookup?&title=Identification%20and%20characterization%20of%20a%20gene%20encoding%20a%20gut-enriched%20Kruppel-like%20factor%20expressed%20during%20growth%20arrest&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.271.33.20009&volume=271&pages=20009-20017&publication_year=1996&author=Shields%2CJM&author=Christy%2CRJ&author=Yang%2CVW's financial summary
• How much revenue does https://doi.org/10.1016%2Fj.cell.2006.07.024 generate?
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=Induction%20of%20pluripotent%20stem%20cells%20from%20mouse%20embryonic%20and%20adult%20fibroblast%20cultures%20by%20defined%20factors&journal=Cell&doi=10.1016%2Fj.cell.2006.07.024&volume=126&pages=663-676&publication_year=2006&author=Takahashi%2CK&author=Yamanaka%2CS?
• Check the income stats for https://doi.org/10.1002%2Fstem.110
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=Novel%20STAT3%20target%20genes%20exert%20distinct%20roles%20in%20the%20inhibition%20of%20mesoderm%20and%20endoderm%20differentiation%20in%20cooperation%20with%20Nanog&journal=Stem%20Cells&doi=10.1002%2Fstem.110&volume=27&pages=1760-1771&publication_year=2009&author=Bourillot%2CPY?
• What's the profit of https://doi.org/10.1371%2Fjournal.pone.0006804?
• How much income is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2009PLoSO...4.6804S earning monthly?
• What are the total earnings of http://scholar.google.com/scholar_lookup?&title=The%20FunGenES%20database%3A%20a%20genomics%20resource%20for%20mouse%20embryonic%20stem%20cell%20differentiation&journal=PLoS%20One&doi=10.1371%2Fjournal.pone.0006804&volume=4&publication_year=2009&author=Schulz%2CH?
• Check the income stats for https://doi.org/10.1242%2Fjcs.027599
• How much money does http://scholar.google.com/scholar_lookup?&title=Klf5%20is%20involved%20in%20self-renewal%20of%20mouse%20embryonic%20stem%20cells&journal=J.%20Cell.%20Sci.&doi=10.1242%2Fjcs.027599&volume=121&pages=2629-2634&publication_year=2008&author=Parisi%2CS generate?
• Get to know https://doi.org/10.1182%2Fblood-2004-07-2681's earnings
• How much profit does http://scholar.google.com/scholar_lookup?&title=Murine%20embryonic%20stem%20cell%20differentiation%20is%20promoted%20by%20SOCS-3%20and%20inhibited%20by%20the%20zinc%20finger%20transcription%20factor%20Klf4&journal=Blood&doi=10.1182%2Fblood-2004-07-2681&volume=105&pages=635-637&publication_year=2005&author=Li%2CY generate?
• How much profit is https://doi.org/10.1016%2Fj.stem.2008.09.003 making per month?
• How much does http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factor%205%20is%20essential%20for%20blastocyst%20development%20and%20the%20normal%20self-renewal%20of%20mouse%20ESCs&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2008.09.003&volume=3&pages=555-567&publication_year=2008&author=Ema%2CM rake in every month?
• How much cash flow does https://doi.org/10.1146%2Fannurev.cellbio.17.1.435 have monthly?
• How much does http://scholar.google.com/scholar_lookup?&title=Embryo-derived%20stem%20cells%3A%20of%20mice%20and%20men&journal=Annu.%20Rev.%20Cell.%20Dev.%20Biol.&doi=10.1146%2Fannurev.cellbio.17.1.435&volume=17&pages=435-462&publication_year=2001&author=Smith%2CAG gross monthly?
• What's the monthly income of https://doi.org/10.1038%2F11926?
• Income figures for http://scholar.google.com/scholar_lookup?&title=Klf4%20is%20a%20transcription%20factor%20required%20for%20establishing%20the%20barrier%20function%20of%20the%20skin&journal=Nat.%20Genet.&doi=10.1038%2F11926&volume=22&pages=356-360&publication_year=1999&author=Segre%2CJA&author=Bauer%2CC&author=Fuchs%2CE
• Discover the revenue of https://doi.org/10.1038%2Fncb1698
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=A%20core%20Klf%20circuitry%20regulates%20self-renewal%20of%20embryonic%20stem%20cells&journal=Nat.%20Cell.%20Biol.&doi=10.1038%2Fncb1698&volume=10&pages=353-360&publication_year=2008&author=Jiang%2CJ?
• Check the income stats for https://doi.org/10.1016%2FS0092-8674%2803%2900392-1
• http://scholar.google.com/scholar_lookup?&title=Functional%20expression%20cloning%20of%20Nanog%2C%20a%20pluripotency%20sustaining%20factor%20in%20embryonic%20stem%20cells&journal=Cell&doi=10.1016%2FS0092-8674%2803%2900392-1&volume=113&pages=643-655&publication_year=2003&author=Chambers%2CI's revenue stream
• What's the financial outcome of https://doi.org/10.1016%2FS0092-8674%2803%2900393-3?
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=The%20homeoprotein%20Nanog%20is%20required%20for%20maintenance%20of%20pluripotency%20in%20mouse%20epiblast%20and%20ES%20cells&journal=Cell&doi=10.1016%2FS0092-8674%2803%2900393-3&volume=113&pages=631-642&publication_year=2003&author=Mitsui%2CK?
• What's the total monthly financial gain of https://doi.org/10.1016%2Fj.devcel.2006.02.020?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Early%20lineage%20segregation%20between%20epiblast%20and%20primitive%20endoderm%20in%20mouse%20blastocysts%20through%20the%20Grb2-MAPK%20pathway&journal=Dev.%20Cell&doi=10.1016%2Fj.devcel.2006.02.020&volume=10&pages=615-624&publication_year=2006&author=Chazaud%2CC&author=Yamanaka%2CY&author=Pawson%2CT&author=Rossant%2CJ
• What are the earnings of https://doi.org/10.1016%2Fj.cell.2008.04.043?
• How much does http://scholar.google.com/scholar_lookup?&title=Integration%20of%20external%20signaling%20pathways%20with%20the%20core%20transcriptional%20network%20in%20embryonic%20stem%20cells&journal=Cell&doi=10.1016%2Fj.cell.2008.04.043&volume=133&pages=1106-1117&publication_year=2008&author=Chen%2CX pull in monthly?
• How much revenue does https://link.springer.com/doi/10.1186/1741-7007-8-128 generate?
• What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Direct%20targets%20of%20Klf5%20transcription%20factor%20contribute%20to%20the%20maintenance%20of%20mouse%20embryonic%20stem%20cell%20undifferentiated%20state&journal=BMC%20Biol.&doi=10.1186%2F1741-7007-8-128&volume=8&publication_year=2010&author=Parisi%2CS?
• Learn how profitable https://link.springer.com/doi/10.1186/1741-7007-8-125 is on a monthly basis
• What are the earnings of http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20transcription%20factors%20and%20control%20of%20pluripotency&journal=BMC%20Biol.&doi=10.1186%2F1741-7007-8-125&volume=8&publication_year=2010&author=Bourillot%2CPY&author=Savatier%2CP?
• What are the earnings of https://doi.org/10.1038%2Fnrc1780?
• How much does http://scholar.google.com/scholar_lookup?&title=KLF4%2C%20p21%20and%20context-dependent%20opposing%20forces%20in%20cancer&journal=Nat.%20Rev.%20Cancer&doi=10.1038%2Fnrc1780&volume=6&pages=11-23&publication_year=2006&author=Rowland%2CBD&author=Peeper%2CDS pull in monthly?
• How much money does https://doi.org/10.1074%2Fjbc.M403724200 generate?
• How much does http://scholar.google.com/scholar_lookup?&title=SOX7%20and%20SOX17%20regulate%20the%20parietal%20endoderm-specific%20enhancer%20activity%20of%20mouse%20laminin%20alpha1%20gene&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.M403724200&volume=279&pages=38055-38061&publication_year=2004&author=Niimi%2CT&author=Hayashi%2CY&author=Futaki%2CS&author=Sekiguchi%2CK gross monthly?
• How much profit does https://doi.org/10.1128%2FMCB.24.23.10492-10503.2004 make?
• What's the profit of http://scholar.google.com/scholar_lookup?&title=Sox7%20plays%20crucial%20roles%20in%20parietal%20endoderm%20differentiation%20in%20F9%20embryonal%20carcinoma%20cells%20through%20regulating%20Gata-4%20and%20Gata-6%20expression&journal=Mol.%20Cell%20Biol.&doi=10.1128%2FMCB.24.23.10492-10503.2004&volume=24&pages=10492-10503&publication_year=2004&author=Futaki%2CS&author=Hayashi%2CY&author=Emoto%2CT&author=Weber%2CCN&author=Sekiguchi%2CK?
• What is the earnings of https://doi.org/10.1038%2Fnbt1167?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Induction%20and%20monitoring%20of%20definitive%20and%20visceral%20endoderm%20differentiation%20of%20mouse%20ES%20cells&journal=Nat.%20Biotechnol.&doi=10.1038%2Fnbt1167&volume=23&pages=1542-1550&publication_year=2005&author=Yasunaga%2CM
• What's the income of https://doi.org/10.1634%2Fstemcells.2005-0344?
• How much does http://scholar.google.com/scholar_lookup?&title=Crucial%20transcription%20factors%20in%20endoderm%20and%20embryonic%20gut%20development%20are%20expressed%20in%20gut-like%20structures%20from%20mouse%20ES%20cells&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2005-0344&volume=24&pages=624-630&publication_year=2006&author=Matsuura%2CR net monthly?
• How much does https://doi.org/10.1111%2Fj.1440-169X.2008.01056.x generate monthly?
• http://scholar.google.com/scholar_lookup?&title=Sox17%20facilitates%20the%20differentiation%20of%20mouse%20embryonic%20stem%20cells%20into%20primitive%20and%20definitive%20endoderm%20in%20vitro&journal=Dev.%20Growth%20Differ.&doi=10.1111%2Fj.1440-169X.2008.01056.x&volume=50&pages=585-593&publication_year=2008&author=Qu%2CXB&author=Pan%2CJ&author=Zhang%2CC&author=Huang%2CSY income
• How much does https://doi.org/10.1016%2Fj.stem.2008.06.018 bring in each month?
• How much does http://scholar.google.com/scholar_lookup?&title=Establishment%20of%20endoderm%20progenitors%20by%20SOX%20transcription%20factor%20expression%20in%20human%20embryonic%20stem%20cells&journal=Cell%20Stem%20Cell&doi=10.1016%2Fj.stem.2008.06.018&volume=3&pages=182-195&publication_year=2008&author=Seguin%2CCA&author=Draper%2CJS&author=Nagy%2CA&author=Rossant%2CJ pull in?
• What's the total monthly financial gain of https://doi.org/10.1101%2Fgad.1833510?
• How much does http://scholar.google.com/scholar_lookup?&title=Sox17%20promotes%20differentiation%20in%20mouse%20embryonic%20stem%20cells%20by%20directly%20regulating%20extraembryonic%20gene%20expression%20and%20indirectly%20antagonizing%20self-renewal&journal=Genes%20Dev.&doi=10.1101%2Fgad.1833510&volume=24&pages=312-326&publication_year=2010&author=Niakan%2CKK earn?
• How much does https://doi.org/10.1038%2F343657a0 generate monthly?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1990Natur.343..657W gross monthly?
• Earnings of http://scholar.google.com/scholar_lookup?&title=Expression%20pattern%20of%20the%20mouse%20T%20gene%20and%20its%20role%20in%20mesoderm%20formation&journal=Nature&doi=10.1038%2F343657a0&volume=343&pages=657-659&publication_year=1990&author=Wilkinson%2CDG&author=Bhatt%2CS&author=Herrmann%2CBG
• How much revenue does https://doi.org/10.1074%2Fjbc.R100043200 produce monthly?
• Income figures for http://scholar.google.com/scholar_lookup?&title=Kruppel-like%20factors%3A%20three%20fingers%20in%20many%20pies&journal=J.%20Biol.%20Chem.&doi=10.1074%2Fjbc.R100043200&volume=276&pages=34355-34358&publication_year=2001&author=Bieker%2CJJ
• How much cash flow does https://doi.org/10.1038%2Fnature11247 have monthly?
• How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2012Natur.489...57T bring in each month?
• How much does http://scholar.google.com/scholar_lookup?&title=An%20integrated%20encyclopedia%20of%20DNA%20elements%20in%20the%20human%20genome&journal=Nature&doi=10.1038%2Fnature11247&volume=489&pages=57-74&publication_year=2012&author=Dunham%2CI pull in?
• How much does https://doi.org/10.1111%2Fj.1365-2443.2010.01390.x earn?
• Income figures for http://scholar.google.com/scholar_lookup?&title=Global%20transcriptomic%20analysis%20of%20murine%20embryonic%20stem%20cell-derived%20brachyury%20%28T%29%20cells&journal=Genes%20Cells&doi=10.1111%2Fj.1365-2443.2010.01390.x&volume=15&pages=209-228&publication_year=2010&author=Doss%2CMX
• How much does https://doi.org/10.1159%2F000329864 bring in each month?
• Monthly income for http://scholar.google.com/scholar_lookup?&title=Induction%20and%20selection%20of%20Sox17-expressing%20endoderm%20cells%20generated%20from%20murine%20embryonic%20stem%20cells&journal=Cells%20Tissues%20Organs&doi=10.1159%2F000329864&volume=195&pages=507-523&publication_year=2012&author=Schroeder%2CIS
• Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11973269
• How much income does http://scholar.google.com/scholar_lookup?&title=Depletion%20of%20definitive%20gut%20endoderm%20in%20Sox17-null%20mutant%20mice&journal=Development&volume=129&pages=2367-2379&publication_year=2002&author=Kanai-Azuma%2CM have?
• https://doi.org/10.1242%2Fdev.02005 income
• How much does http://scholar.google.com/scholar_lookup?&title=Characterization%20of%20mesendoderm%3A%20a%20diverging%20point%20of%20the%20definitive%20endoderm%20and%20mesoderm%20in%20embryonic%20stem%20cell%20differentiation%20culture&journal=Development&doi=10.1242%2Fdev.02005&volume=132&pages=4363-4374&publication_year=2005&author=Tada%2CS generate monthly?
• How much profit is https://doi.org/10.1634%2Fstemcells.2005-0256 making per month?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=In%20vitro%20modeling%20of%20paraxial%20and%20lateral%20mesoderm%20differentiation%20reveals%20early%20reversibility&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2005-0256&volume=24&pages=575-586&publication_year=2006&author=Sakurai%2CH?
• What's https://doi.org/10.1101%2Fgad.968802's gross income?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Differentiation%20of%20embryonic%20stem%20cells%20is%20induced%20by%20GATA%20factors&journal=Genes%20Dev.&doi=10.1101%2Fgad.968802&volume=16&pages=784-789&publication_year=2002&author=Fujikura%2CJ generate?
• https://link.springer.com/doi/10.1186/1471-213X-7-80 income
• What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Extra-embryonic%20endoderm%20cells%20derived%20from%20ES%20cells%20induced%20by%20GATA%20factors%20acquire%20the%20character%20of%20XEN%20cells&journal=BMC%20Dev.%20Biol.&doi=10.1186%2F1471-213X-7-80&volume=7&publication_year=2007&author=Shimosato%2CD&author=Shiki%2CM&author=Niwa%2CH?
• What are the earnings of https://doi.org/10.1038%2F86912?
• http://scholar.google.com/scholar_lookup?&title=The%20amnionless%20gene%2C%20essential%20for%20mouse%20gastrulation%2C%20encodes%20a%20visceral-endoderm-specific%20protein%20with%20an%20extracellular%20cysteine-rich%20domain&journal=Nat.%20Genet.&doi=10.1038%2F86912&volume=27&pages=412-416&publication_year=2001&author=Kalantry%2CS's revenue stream
• https://doi.org/10.1006%2Fdbio.2002.0810's financial summary
• How profitable is http://scholar.google.com/scholar_lookup?&title=Disabled-2%20is%20essential%20for%20endodermal%20cell%20positioning%20and%20structure%20formation%20during%20mouse%20embryogenesis&journal=Dev.%20Biol.&doi=10.1006%2Fdbio.2002.0810&volume=251&pages=27-44&publication_year=2002&author=Yang%2CDH?
• What's the income generated by https://doi.org/10.1182%2Fblood-2005-10-4120 each month?
• How much does http://scholar.google.com/scholar_lookup?&title=Acceleration%20of%20mesoderm%20development%20and%20expansion%20of%20hematopoietic%20progenitors%20in%20differentiating%20ES%20cells%20by%20the%20mouse%20Mix-like%20homeodomain%20transcription%20factor&journal=Blood&doi=10.1182%2Fblood-2005-10-4120&volume=107&pages=3122-3130&publication_year=2006&author=Willey%2CS pull in monthly?
• Explore the financials of https://doi.org/10.1242%2Fdev.054775
• How much money does http://scholar.google.com/scholar_lookup?&title=Klf5%20regulates%20lineage%20formation%20in%20the%20pre-implantation%20mouse%20embryo&journal=Development&doi=10.1242%2Fdev.054775&volume=137&pages=3953-3963&publication_year=2010&author=Lin%2CSC&author=Wani%2CMA&author=Whitsett%2CJ%20A&author=Wells%2CJM make?
• See how much https://doi.org/10.1634%2Fstemcells.2007-0953 makes per month
• http://scholar.google.com/scholar_lookup?&title=Derivation%20and%20cloning%20of%20a%20novel%20Rhesus%20ES%20cell%20line%20stably%20expressing%20tau-GFP&journal=Stem%20Cells&doi=10.1634%2Fstemcells.2007-0953&volume=26&pages=1444-1453&publication_year=2008&author=Wianny%2CF's financial summary
• Profit of https://doi.org/10.1006%2Fdbio.1999.9544
• Earnings of http://scholar.google.com/scholar_lookup?&title=Direct%20activation%20of%20a%20GATA6%20cardiac%20enhancer%20by%20Nkx2.5%3A%20evidence%20for%20a%20reinforcing%20regulatory%20network%20of%20Nkx2.5%20and%20GATA%20transcription%20factors%20in%20the%20developing%20heart&journal=Dev.%20Biol.&doi=10.1006%2Fdbio.1999.9544&volume=217&pages=301-309&publication_year=2000&author=Molkentin%2CJD
• What's the profit of https://doi.org/10.1016%2Fj.scr.2012.10.004?
• See how much http://scholar.google.com/scholar_lookup?&title=A%20short%20G1%20phase%20is%20an%20intrinsic%20determinant%20of%20naive%20embryonic%20stem%20cell%20pluripotency&journal=Stem%20Cell%20Res.&doi=10.1016%2Fj.scr.2012.10.004&volume=10&pages=118-131&publication_year=2013&author=Coronado%2CD makes per month
• How much revenue does https://doi.org/10.1002%2F%28SICI%291097-0215%2819980302%2975%3A5%3C767%3A%3AAID-IJC17%3E3.0.CO%3B2-3 generate?
• Get to know http://scholar.google.com/scholar_lookup?&title=Gastric%20M1%20mucin%2C%20an%20early%20oncofetal%20marker%20of%20colon%20carcinogenesis%2C%20is%20encoded%20by%20the%20MUC5AC%20gene&journal=Int.%20J.%20Cancer&doi=10.1002%2F%28SICI%291097-0215%2819980302%2975%3A5%3C767%3A%3AAID-IJC17%3E3.0.CO%3B2-3&volume=75&pages=767-773&publication_year=1998&author=Bara%2CJ's earnings
• What's the monthly money flow for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=4187091?
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232189's revenue stream
• How much money does http://scholar.google.com/scholar_lookup?&title=The%20in%20vivo%20staining%20of%20bone%20with%20alizarin%20red%20S&journal=J.%20Anat.&volume=105&pages=533-545&publication_year=1969&author=Vilmann%2CH make?
• See how much https://doi.org/10.1093%2Fbiostatistics%2F4.2.249 makes per month
• How much does http://scholar.google.com/scholar_lookup?&title=Exploration%2C%20normalization%2C%20and%20summaries%20of%20high%20density%20oligonucleotide%20array%20probe%20level%20data&journal=Biostatistics&doi=10.1093%2Fbiostatistics%2F4.2.249&volume=4&pages=249-264&publication_year=2003&author=Irizarry%2CRA bring in each month?
• Learn how profitable https://doi.org/10.1073%2Fpnas.95.25.14863 is on a monthly basis
• How much profit is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=1998PNAS...9514863E making per month?
• What's the income of http://scholar.google.com/scholar_lookup?&title=Cluster%20analysis%20and%20display%20of%20genome-wide%20expression%20patterns&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&doi=10.1073%2Fpnas.95.25.14863&volume=95&pages=14863-14868&publication_year=1998&author=Eisen%2CMB&author=Spellman%2CPT&author=Brown%2CPO&author=Botstein%2CD?
• What is the monthly revenue of https://doi.org/10.1038%2Femboj.2013.31?
• How much income does http://scholar.google.com/scholar_lookup?&title=Oct4%20switches%20partnering%20from%20Sox2%20to%20Sox17%20to%20reinterpret%20the%20enhancer%20code%20and%20specify%20endoderm&journal=EMBO%20J.&doi=10.1038%2Femboj.2013.31&volume=32&pages=938-953&publication_year=2013&author=Aksoy%2CI have?
• Learn about the earnings of https://link.springer.com/doi/10.1186/gb-2008-9-9-r137
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Model-based%20analysis%20of%20ChIP-Seq%20%28MACS%29&journal=Genome%20Biol.&doi=10.1186%2Fgb-2008-9-9-r137&volume=9&publication_year=2008&author=Zhang%2CY have monthly?
• How much cash flow does https://citation-needed.springer.com/v2/references/10.1038/ncomms4719?format=refman&flavour=references have monthly?
• See how much http://www.a-star.edu.sg makes per month
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ir%C3%A8ne%20Aksoy bring in?
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ir%C3%A8ne%20Aksoy%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• What is the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Vincent%20Giudice?
• How profitable is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Vincent%20Giudice%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Edwige%20Delahaye earns monthly
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Edwige%20Delahaye%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• Check the income stats for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Florence%20Wianny
• Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Florence%20Wianny%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Maxime%20Aubry?
• What's the profit of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Maxime%20Aubry%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• What's the income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Magali%20Mure?
• Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Magali%20Mure%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jiaxuan%20Chen net monthly?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jiaxuan%20Chen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ralf%20Jauch produce monthly?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ralf%20Jauch%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Gireesh%20K.%20Bogu
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Gireesh%20K.%20Bogu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Tobias%20Nolden's financial summary
• What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Tobias%20Nolden%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Heinz%20Himmelbauer make?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Heinz%20Himmelbauer%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
• What's the income generated by https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Michael%20Xavier%20Doss each month?
• What's the monthly money flow for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Michael%20Xavier%20Doss%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Agapios%20Sachinidis generate?
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Agapios%20Sachinidis%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en income
• Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Herbert%20Schulz
• How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Herbert%20Schulz%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Oliver%20Hummel pull in monthly?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Oliver%20Hummel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en rake in every month?
• What is the monthly revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Paola%20Martinelli?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Paola%20Martinelli%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
• What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Norbert%20H%C3%BCbner?
• What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Norbert%20H%C3%BCbner%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Lawrence%20W.%20Stanton have monthly?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Lawrence%20W.%20Stanton%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en make?
• What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Francisco%20X.%20Real's gross income?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Francisco%20X.%20Real%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
• What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pierre-Yves%20Bourillot?
• Earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pierre-Yves%20Bourillot%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• What are the total earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pierre%20Savatier?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pierre%20Savatier%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
• Explore the financials of https://static-content.springer.com/esm/art%3A10.1038%2Fncomms4719/MediaObjects/41467_2014_BFncomms4719_MOESM123_ESM.pdf
• What's the profit of https://s100.copyright.com/AppDispatchServlet?title=Klf4%20and%20Klf5%20differentially%20inhibit%20mesoderm%20and%20endoderm%20differentiation%20in%20embryonic%20stem%20cells&author=Ir%C3%A8ne%20Aksoy%20et%20al&contentID=10.1038%2Fncomms4719©right=Springer%20Nature%20Limited&publication=2041-1723&publicationDate=2014-04-28&publisherName=SpringerNature&orderBeanReset=true?
• How much does https://crossmark.crossref.org/dialog/?doi=10.1038/ncomms4719 pull in?
• Profit of https://citation-needed.springer.com/v2/references/10.1038/ncomms4719?format=refman&flavour=citation
• How much does https://doi.org/10.1038/s41467-021-26125-x make?
• What's the income of https://doi.org/10.1038/s41467-021-24035-6?
• Monthly income for https://doi.org/10.1038/s41598-020-76951-0
• What's the financial gain of https://doi.org/10.1007/s11626-019-00341-8?
• How much does https://doi.org/10.1038/s41467-017-02786-5 make?
• What's https://www.protocols.io/'s gross income?
• Check the income stats for https://www.natureindex.com/
• What's the income generated by http://www.naturechina.com each month?
• What's the financial gain of https://www.natureasia.com/ja-jp?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref