PMC . NCBI . NLM . NIH . GOV {
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We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC2753677/.
Title:
Isoform-specific Inhibition of Cyclophilins - PMC
Description:
Cyclophilins belong to the enzyme class of peptidyl prolyl cis/trans isomerases which catalyze the cis/trans isomerization of prolyl bonds in peptides and proteins in different folding states. Cyclophilins have been shown to be involved in a ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Title:
Isoform-specific Inhibition of Cyclophilins - PMC
Description:
Cyclophilins belong to the enzyme class of peptidyl prolyl cis/trans isomerases which catalyze the cis/trans isomerization of prolyl bonds in peptides and proteins in different folding states. Cyclophilins have been shown to be involved in a ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Matching Content Categories {📚}
- Education
- Science
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Custom-built
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🌠 Phenomenal Traffic: 5M - 10M visitors per month
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How Does Pmc.ncbi.nlm.nih.gov Make Money? {💸}
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Keywords {🔍}
cypa, doi, google, scholar, pubmed, compound, cyclophilin, csa, cypb, binding, cyclophilins, cells, ppiase, activity, inhibition, human, pmc, aryl, site, complex, active, pin, inhibitor, free, ligand, article, prolyl, protein, presence, transition, state, figure, cistrans, cyclosporin, concentrations, assay, constant, anisotropy, inhibitors, hepes, concentration, cell, determined, chemotactic, buffer, shown, chemotaxis, ocfnhchnhcochdsercsa, table, mol,
Topics {✒️}
suc-ala-ala-pro-phe-4-nitroanilide substrate suc-ala-ala-pro-phe-pna suc-ala-ala-pro-phe-pna peptidyl-prolyl cis-trans isomerase cypa/ala-pro complex suggested peptidyl-prolyl isomerase inhibitors cis/trans isomerization kinetic bicyclic cis-pro mimics peptidyl-prolyl isomerase fluorescence polarization-based assay pseudo-double bond character protease-free ppiase assay cis/trans isomerization d-ser]8csa/csa-complex peptidyl-prolyl isomerases d-ser]8csa/cypa complex solvent-accessible surface area peptidyl prolyl isomerization transcriptional coregulator snw/skip trigger integrin-mediated adhesion itc-based competition assay alkene cis-proline mimic pmc beta search spiroannulated benzofuranone type labeled [ser]8-csa derivative high-affinity ligand l1 prolyl isomerase cyclophilin virus rna polymerase describe small-molecule inhibitors peptidyl prolyl bonds low-affinity ligand l2 protease free assay protease-free assay d-ser]8csa interaction high-affinity coupling ligand cyclophilin-catalyzed reaction depends 1021/bi9007287 isoform-specific inhibition transition-state analogue inhibitors high-affinity peptide inhibition titration calorimetry fluorescein polarization measurement x-ray data suggests including severe sepsis respective cyp/csa complexes isothermal titration d-ser]8csa protein phosphatase activity escherichia coli cyclophilins nih grant ai-067254 ligand displacement experiments
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