
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes - PubMed
Description:
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their similar mechanisms of inhibition of cell signaling suggest that their associated immunophilin complexes interact with a common target. We report here that the complexes cyclop …
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Keywords {🔍}
pmid, doi, calcineurin, metabolism, proteins, molecular, cited, cell, complexes, binding, agents, pmc, states, similar, articles, mesh, substances, aug, protein, free, article, tacrolimus, nih, main, ncbi, abstract, information, resources, common, cyclosporin, inhibition, signaling, phosphatase, calmodulin, activity, pubmed, peptidylprolyl, isomerase, immunosuppressive, epub, amino, acid, sequence, calmodulinbinding, oligopeptides, phosphoprotein, phosphatases, pubchem, hhsunited, hhs,
Topics {✒️}
peptidyl-prolyl cis-trans isomerase united states government calmodulin-dependent phosphatase calcineurin calcineurin-calmodulin binding antimicrob agents chemother anti-hepatitis protein protein require calmodulin funding linkout adult mice main page content similar articles cited 7680683 molecular analysis d-diaminopropyl-8-cyclosporin analogues correlates targeting artemisinin-resistant malaria ca mesh keyword divalent cloning forming drug-dependent complexes hhs 7520696 immunosuppressive activity calcineurin phosphatase activity pubchem substance grants literature sources drug-immunophilin complexes immunophilin complexes interact cited virus drug alisporivir resources cell cell signaling pathways actions rios coronado pe health trends biochem sci nat cardiovasc res hinds td jr similar mechanisms cell signaling suggest research support calcineurin fkbp-fk506 complexes complexes cyclophilin-csa abstract antimalarial action d-diaminobutyryl-8 cell receptor schreiber sl pubmed wordmark pubmed logo
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