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Title:
Isoform-specific inhibition of cyclophilins - PubMed
Description:
Cyclophilins belong to the enzyme class of peptidyl prolyl cis-trans isomerases which catalyze the cis-trans isomerization of prolyl bonds in peptides and proteins in different folding states. Cyclophilins have been shown to be involved in a multitude of cellular functions like cell growth, prolifer …
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Keywords {🔍}
cyclophilins, cyclophilin, doi, pmid, pubmed, inhibitors, pmc, chemistry, cistrans, proteins, free, article, metabolism, enzyme, isoenzymes, aryl, figure, epub, dec, states, articles, mesh, inhibition, human, cypa, isomerase, fischer, review, cyclosporine, nih, antagonists, indans, recombinant, pubchem, main, ncbi, similar, cited, references, information, resources, prolyl, functions, inhibitor, binding, fluorescence, cyclosporin, chemical, liu, protein,
Topics {✒️}
fluorescence polarization-based assay / chemistry cyclophilin cyclophilin inhibitors main page content peptidyl-prolyl cis-trans isomerase united states government immunophilin inhibitors cyclosporine cyclophilin cell-impermeable cyclosporine dtbp-mediated cross-dehydrogenative coupling enzyme class enzyme catalysis similar articles cited identical proteins funding linkout literature sources proteins escherichia coli cyclophilins virus ns5a protein cyclophilins sebastian daum 1 human nuclear cyclophilins extramural research support pubchem substance grants fluorescence anisotropy articles references fischer cis-trans isomerization cypb-mediated chemotaxis microbial cyclophilins resources biochemistry folding states cyclophilins mesh keyword cypa binding residual ppiase activity hhs mouse cd4 specific tryptophan residue cyclophilin-cyclosporin carbon quaternary centers derivative reduces pathology allergic lung inflammation fkbp-fk506 complexes small-molecule inhibitor isoform-specific inhibition small molecule inhibition chem inf model spiral ganglion cells cited cyclophilin family pubmed fischer
Questions {❓}
- Cyclophilin D in Mitochondrial Dysfunction: A Key Player in Neurodegeneration?
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