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We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3852190/.
Title:
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter (MCU) - PMC
Description:
Mitochondrial calcium has been postulated to regulate a wide range of processes from bioenergetics to cell death. Here, we characterize a mouse model that lacks expression of the recently discovered mitochondrial calcium uniporter (MCU). ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Title:
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter (MCU) - PMC
Description:
Mitochondrial calcium has been postulated to regulate a wide range of processes from bioenergetics to cell death. Here, we characterize a mouse model that lacks expression of the recently discovered mitochondrial calcium uniporter (MCU). ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
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What is the average monthly size of pmc.ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {🔍}
mcu, calcium, doi, mitochondrial, mice, mitochondria, fig, pubmed, google, scholar, cell, uptake, muscle, levels, mefs, skeletal, expression, pmc, death, addition, ptp, article, physiological, cells, supplemental, similar, observed, role, opening, pdh, free, basal, activity, results, rapid, isolated, cardiac, uniporter, phosphorylation, evidence, tissues, increase, experiments, wild, type, cytosolic, data, fluorescence, absence, biol,
Topics {✒️}
calcium-sensitive phosphatase pdp129 continuous sirna-mediated knockdown fiber-specific mrna abundance original mito-aequorin adenovirus pmc beta search mitochondrial-targeted aequorin construct calcium green-5n fluorescence mitochondrial-dependent atp production predominantly oxidative/slow twitch ion-impermeable imm requires calcium-induced ptp opening histamine-induced cytosolic calcium nhlbi microscopy core low-calcium-dependent mechanisms full speed sprint supplementary materials included mitochondrial calcium regulates inset-western blot analysis permeability transition pore fluo-4ff fluorescence calcium green-5n mitochondrial oxygen consumption nat cell biol muscle types including er calcium uptake mitochondrial calcium uniporter mitochondrial enzymes involved mitochondrial permeability transition oxygen consumption rate nih intramural funds rhod-2 fluorescent measurements regulates cellular metabolism mitochondrial calcium uptake increased power output wild type levels myocardial ischemia-reperfusion injury pyruvate dehydrogenase phosphatase mitochondrial uptake continued rabbit cardiac myocytes wild type mitochondria serum lactate levels total pdh levels wild type mcu license information pmcid epitope-tagged form e1-α subunit rate pressure product specific channel termed skeletal muscle function skeletal muscle bioenergetics33-35
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