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Title:
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter - PubMed
Description:
Mitochondrial calcium has been postulated to regulate a wide range of processes from bioenergetics to cell death. Here, we characterize a mouse model that lacks expression of the recently discovered mitochondrial calcium uniporter (MCU). Mitochondria derived from MCU(-/-) mice have no apparent capac …
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Keywords {🔍}
calcium, mitochondrial, doi, pmid, pmc, mcu, mice, uniporter, pubmed, free, article, mitochondria, metabolism, cell, biol, epub, muscle, murphy, uptake, permeability, transition, pore, figure, skeletal, articles, mesh, dec, regulates, transport, main, ncbi, abstract, figures, similar, cited, references, resources, nat, ncb, nov, finkel, regulate, activity, pyruvate, dehydrogenase, ptp, physiology, chem, oct, review,
Topics {✒️}
pyruvate dehydrogenase permeability transition pore mitochondrial calcium uniporter main page content mitochondria transport calcium mitochondrial calcium revealed mitochondrial matrix calcium cardiac muscle rapidly uptake calcium ' mitochondrial calcium basal metabolism calcium uptake united states government mcub regulates mitochondrial ca2+ change regulate mammalian physiology transport mechanisms cold stress-induced ferroptosis skeletal muscle figures mice exhibited alterations mice lacked evidence cell calcium ca ion uptake funding linkout lack mitochondrial ca mitochondrial nclx mesh keyword similar articles cited mouse model protect mcu molecular composition mol cell cardiol nat cell biol calcium perform strenuous work cells impaired synaptic transmission distinct hippocampal circuits biochim biophys acta medgen protein protein mice lacking rat kidney mitochondria comment pubmed wordmark pubmed logo mcu ptp inhibitor cyclosporin de la fuente
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- How does mitochondrial Ca2+ change during ischemia and reperfusion?
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