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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
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  6. Keywords
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We began analyzing https://www.nature.com/articles/nrm2639, but it redirected us to https://www.nature.com/articles/nrm2639. The analysis below is for the second page.

Title[redir]:
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system | Nature Reviews Molecular Cell Biology
Description:
Tie receptors and their angiopoietin ligands have important functions during embryonic vessel assembly and maturation, and control adult vascular homeostasis. The structural characteristics and the spatio-temporal regulation of these receptors and ligands provide important insights into their functions. Angiogenesis, the growth of blood vessels, is a fundamental biological process that controls embryonic development and is also involved in numerous life-threatening human diseases. Much work in the field of angiogenesis research has centred on the vascular endothelial growth factor (VEGF)–VEGF receptor system. The Tie receptors and their angiopoietin (Ang) ligands have been identified as the second vascular tissue-specific receptor Tyr kinase system. Ang–Tie signalling is essential during embryonic vessel assembly and maturation, and functions as a key regulator of adult vascular homeostasis. The structural characteristics and the spatio-temporal regulation of the expression of receptors and ligands provide unique insights into the functions of this vascular signalling system.

Matching Content Categories {📚}

  • Education
  • Science
  • Telecommunications

Content Management System {📝}

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Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


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How Does Doi.org Make Money? {💸}

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Keywords {🔍}

pubmed, google, scholar, cas, article, angiopoietin, tie, cell, endothelial, vascular, receptor, central, cells, angiogenesis, growth, nature, res, kinase, cancer, biol, ang, blood, factor, role, expression, tumor, tyrosine, vessel, development, chem, mice, regulation, sci, usa, signalling, activation, pathway, research, access, proc, natl, acad, med, circ, system, ligand, kim, embryonic, survival, vessels,

Topics {✒️}

nature portfolio permissions reprints privacy policy platelet-derived growth factor-β vascular endothelial-protein-tyrosine phosphatase advertising tie2-signalling-dependent anti-permeability effects adenovirus-delivered anti-tie-2 intrabody nature cell biol biomedical research center social media nature rev national research laboratory angiopoietin/tie research pten/pi3-kinase/akt α-smooth muscle actin author information authors tools prevents endothelial-cell apoptosis receptor-tyrosine kinase tie2 nature struct nature med junctional cell–cell contact angiopoietin-1-mediated endothelial permeability atherosclerosis-prone vascular niches tumour-necrosis factor-α author correspondence angiogenesis research ang1/tie2 signaling pathway nature 376 nature 453 nature angiopoietin 1/tie2/serotonin pathway surrounding peri-endothelial cells vascular lineage-specific genes mannitol-induced apoptosis angiopoietin-1-dependent cell migration smooth muscle cells fibrinogen/angiopoietin-related protein peri-endothelial pericyte coverage cell–substratum contacts regulated cell type-specific expression flow-dependent endothelial phenotypes receptor tyrosine kinases hematopoietic stem cells springerlink instant access personal data epidermal growth factor permissions gou young koh

Schema {🗺️}

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         description: Tie receptors and their angiopoietin ligands have important functions during embryonic vessel assembly and maturation, and control adult vascular homeostasis. The structural characteristics and the spatio-temporal regulation of these receptors and ligands provide important insights into their functions. Angiogenesis, the growth of blood vessels, is a fundamental biological process that controls embryonic development and is also involved in numerous life-threatening human diseases. Much work in the field of angiogenesis research has centred on the vascular endothelial growth factor (VEGF)–VEGF receptor system. The Tie receptors and their angiopoietin (Ang) ligands have been identified as the second vascular tissue-specific receptor Tyr kinase system. Ang–Tie signalling is essential during embryonic vessel assembly and maturation, and functions as a key regulator of adult vascular homeostasis. The structural characteristics and the spatio-temporal regulation of the expression of receptors and ligands provide unique insights into the functions of this vascular signalling system.
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      headline:Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
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