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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s00251-021-01237-2, but it redirected us to https://link.springer.com/article/10.1007/s00251-021-01237-2. The analysis below is for the second page.

Title[redir]:
Secreted immunoglobulin domain effector molecules of invertebrates and management of gut microbial ecology | Immunogenetics
Description:
The origins of a “pass-through” gut in early bilaterians facilitated the exploration of new habitats, motivated the innovation of feeding styles and behaviors, and helped drive the evolution of more complex organisms. The gastrointestinal tract has evolved to consist of a series of interwoven exchanges between nutrients, host immunity, and an often microbe-rich environmental interface. Not surprisingly, animals have expanded their immune repertoires to include soluble effectors that can be secreted into luminal spaces, e.g., in the gut, facilitating interactions with microbes in ways that influence their settlement dynamics, virulence, and their interaction with other microbes. The immunoglobulin (Ig) domain, which is also found in some non-immune molecules, is recognized as one of the most versatile recognition domains lying at the interface of innate and adaptive immunity; among vertebrates, secreted Igs are known to play crucial roles in the management of gut microbial communities. In this mini-review, we will focus on secreted immune effectors possessing Ig-like domains in invertebrates, such as the fibrinogen-related effector proteins first described in the gastropod Biomphalaria glabrata, the Down syndrome cellular adhesion molecule first described in the arthropod, Drosophila melanogaster, and the variable region-containing chitin-binding proteins of the protochordates. We will highlight our current understanding of their function and their potential role, if not yet recognized, in the establishment and maintenance of host-microbial interfaces and argue that these Igs are likely also essential to microbiome management.

Matching Content Categories {📚}

  • Science
  • Education
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🏙️ Massive Traffic: 50M - 100M visitors per month


Based on our best estimate, this website will receive around 80,904,851 visitors per month in the current month.

check SE Ranking
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check Semrush

How Does Doi.org Make Money? {💸}

The income method remains a mystery to us.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Doi.org might be plotting its profit, but the way they're doing it isn't detectable yet.

Keywords {🔍}

pubmed, article, google, scholar, cas, immunol, immune, central, gut, immunity, dishaw, immunoglobulin, evolution, proteins, microbiota, cell, interactions, innate, system, biol, cannon, comp, dev, secreted, liberti, domains, variable, rev, nat, httpsdoiorgjdci, domain, molecules, microbial, receptor, dscam, httpsdoiorgs, content, host, role, httpsdoiorg, superfamily, litman, front, plos, intestinal, privacy, cookies, immunogenetics, effector, manuscript,

Topics {✒️}

month download article/chapter c-type lectin maintains insect-immune protein belonging humoral immune responses heterogeneous carbohydrate-binding proteins hemocyte-specific frep13 abrogates fibrinogen-related effector proteins immune-type receptor secreted immune effectors litopenaeus vannamei dscam host gut-bacteria interactions article immunogenetics aims microbe-rich environmental interface bacterial-fungal interactions article liberti full article pdf immune receptor diversity immune effector system interaction molecules hypervariable immunoglobulin domain cell adhesion molecules immune evasion innate immune receptors exogenous bacterial population adema cm host-microbe interactions innate immune system innate immune systems innate host defense host-microbial interfaces privacy choices/manage cookies immune-directed support snail biomphalaria glabrata dishaw lj parasite-microbiota interactions chitin-binding proteins flores-torres ja gastropod biomphalaria glabrata reconstructing immune phylogeny mosquito midgut microbiota gut microbiota unaffected include soluble effectors rich microbial communities cell surface recognition immune molecules early bilaterians facilitated lectin complement pathway mediates biofilm formation gut microbial communities gut microbial ecology

Questions {❓}

  • Mussmann R, Du Pasquier L, Hsu E (1996) Is Xenopus IgX an analog of IgA?
  • The Gut Microbiome and Its Marriage to the Immune System: Can We Change It All?

Schema {🗺️}

WebPage:
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         headline:Secreted immunoglobulin domain effector molecules of invertebrates and management of gut microbial ecology
         description:The origins of a “pass-through” gut in early bilaterians facilitated the exploration of new habitats, motivated the innovation of feeding styles and behaviors, and helped drive the evolution of more complex organisms. The gastrointestinal tract has evolved to consist of a series of interwoven exchanges between nutrients, host immunity, and an often microbe-rich environmental interface. Not surprisingly, animals have expanded their immune repertoires to include soluble effectors that can be secreted into luminal spaces, e.g., in the gut, facilitating interactions with microbes in ways that influence their settlement dynamics, virulence, and their interaction with other microbes. The immunoglobulin (Ig) domain, which is also found in some non-immune molecules, is recognized as one of the most versatile recognition domains lying at the interface of innate and adaptive immunity; among vertebrates, secreted Igs are known to play crucial roles in the management of gut microbial communities. In this mini-review, we will focus on secreted immune effectors possessing Ig-like domains in invertebrates, such as the fibrinogen-related effector proteins first described in the gastropod Biomphalaria glabrata, the Down syndrome cellular adhesion molecule first described in the arthropod, Drosophila melanogaster, and the variable region-containing chitin-binding proteins of the protochordates. We will highlight our current understanding of their function and their potential role, if not yet recognized, in the establishment and maintenance of host-microbial interfaces and argue that these Igs are likely also essential to microbiome management.
         datePublished:2022-01-06T00:00:00Z
         dateModified:2022-01-06T00:00:00Z
         pageStart:99
         pageEnd:109
         sameAs:https://doi.org/10.1007/s00251-021-01237-2
         keywords:
            Immunoglobulin domain
            Innate immunity
            Host-microorganism interaction
            Secreted immune molecules
            Invertebrate immunity
            Microbiota
            Immunology
            Human Genetics
            Gene Function
            Cell Biology
            Allergology
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                        name:Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, USA
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      headline:Secreted immunoglobulin domain effector molecules of invertebrates and management of gut microbial ecology
      description:The origins of a “pass-through” gut in early bilaterians facilitated the exploration of new habitats, motivated the innovation of feeding styles and behaviors, and helped drive the evolution of more complex organisms. The gastrointestinal tract has evolved to consist of a series of interwoven exchanges between nutrients, host immunity, and an often microbe-rich environmental interface. Not surprisingly, animals have expanded their immune repertoires to include soluble effectors that can be secreted into luminal spaces, e.g., in the gut, facilitating interactions with microbes in ways that influence their settlement dynamics, virulence, and their interaction with other microbes. The immunoglobulin (Ig) domain, which is also found in some non-immune molecules, is recognized as one of the most versatile recognition domains lying at the interface of innate and adaptive immunity; among vertebrates, secreted Igs are known to play crucial roles in the management of gut microbial communities. In this mini-review, we will focus on secreted immune effectors possessing Ig-like domains in invertebrates, such as the fibrinogen-related effector proteins first described in the gastropod Biomphalaria glabrata, the Down syndrome cellular adhesion molecule first described in the arthropod, Drosophila melanogaster, and the variable region-containing chitin-binding proteins of the protochordates. We will highlight our current understanding of their function and their potential role, if not yet recognized, in the establishment and maintenance of host-microbial interfaces and argue that these Igs are likely also essential to microbiome management.
      datePublished:2022-01-06T00:00:00Z
      dateModified:2022-01-06T00:00:00Z
      pageStart:99
      pageEnd:109
      sameAs:https://doi.org/10.1007/s00251-021-01237-2
      keywords:
         Immunoglobulin domain
         Innate immunity
         Host-microorganism interaction
         Secreted immune molecules
         Invertebrate immunity
         Microbiota
         Immunology
         Human Genetics
         Gene Function
         Cell Biology
         Allergology
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                     type:PostalAddress
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                  name: Morsani College of Medicine, University of South Florida
                  address:
                     name:Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, USA
                     type:PostalAddress
                  type:Organization
                  name: Children’s Research Institute
                  address:
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         name:Biology and Evolution of Marine Organisms (BEOM), Naples, Italy
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      address:
         name:Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, USA
         type:PostalAddress
      name: Children’s Research Institute
      address:
         name:Division of Molecular Genetics, Children’s Research Institute, St. Petersburg, USA
         type:PostalAddress
      name:University of South Florida
      address:
         name:Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, USA
         type:PostalAddress
      name: Children’s Research Institute
      address:
         name:Division of Molecular Genetics, Children’s Research Institute, St. Petersburg, USA
         type:PostalAddress
      name: Morsani College of Medicine, University of South Florida
      address:
         name:Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, USA
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               name:Biology and Evolution of Marine Organisms (BEOM), Naples, Italy
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            name: Children’s Research Institute
            address:
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               type:PostalAddress
            type:Organization
      name:Celine Grace F. Atkinson
      affiliation:
            name:University of South Florida
            address:
               name:Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, USA
               type:PostalAddress
            type:Organization
            name: Children’s Research Institute
            address:
               name:Division of Molecular Genetics, Children’s Research Institute, St. Petersburg, USA
               type:PostalAddress
            type:Organization
      name:Larry J. Dishaw
      url:http://orcid.org/0000-0002-2705-4573
      affiliation:
            name: Morsani College of Medicine, University of South Florida
            address:
               name:Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, USA
               type:PostalAddress
            type:Organization
            name: Children’s Research Institute
            address:
               name:Division of Molecular Genetics, Children’s Research Institute, St. Petersburg, USA
               type:PostalAddress
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      email:[email protected]
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      name:Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, USA
      name:Division of Molecular Genetics, Children’s Research Institute, St. Petersburg, USA
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External Links {🔗}(324)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.3s.