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  7. Topics
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We began analyzing https://link.springer.com/article/10.1007/BF02603120, but it redirected us to https://link.springer.com/article/10.1007/BF02603120. The analysis below is for the second page.

Title[redir]:
Progressive sequence alignment as a prerequisitetto correct phylogenetic trees | Journal of Molecular Evolution
Description:
A progressive alignment method is described that utilizes the Needleman and Wunsch pairwise alignment algorithm iteratively to achieve the multiple alignment of a set of protein sequences and to construct an evolutionary tree depicting their relationship. The sequences are assumed a priori to share a common ancestor, and the trees are constructed from difference matrices derived directly from the multiple alignment. The thrust of the method involves putting more trust in the comparison of recently diverged sequences than in those evolved in the distant past. In particular, this rule is followed: โ€œonce a gap, always a gapโ€. The method has been applied to three sets of protein sequences: 7 superoxide dismutases, 11 globins, and 9 tyrosine kinase-like sequences. Multiple alignments and phylogenetic trees for these sets of sequences were determined and compared with trees derived by conventional pairwise treatments. In several instances, the progressive method led to trees that appeared to be more in line with biological expectations than were trees obtained by more commonly used methods.

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  • Science
  • Education
  • Fitness & Wellness

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Custom-built

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Traffic Estimate {๐Ÿ“ˆ}

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๐ŸŒ  Phenomenal Traffic: 5M - 10M visitors per month


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Keywords {๐Ÿ”}

google, scholar, article, cas, pubmed, sequence, mol, trees, method, sequences, superoxide, evol, evolutionary, dismutase, biol, protein, research, alignment, phylogenetic, doolittle, structure, dayhoff, data, usa, amino, acid, fitch, privacy, cookies, content, journal, search, molecular, multiple, bannister, publish, evolution, progressive, feng, sets, access, related, proteins, leiognathi, proc, natl, acad, sci, atlas, national,

Topics {โœ’๏ธ}

month download article/chapter cu-zn superoxide dismutase copper/zinc superoxide dismutase sequence phylogeny research full article pdf amino acid sequence human superoxide dismutase privacy choices/manage cookies progressive sequence alignment article feng sequence homologies amonge evolutionarily related groupings distantly related species conventional pairwise treatments multiple alignments related subjects molecular evolution aims molecular restoration studies progressive alignment method progressive method led estimated phylogenetic trees amino acid sequences calculating evolutionary trees european economic area silver spring md de jong ww kim s-ma ponyfish tophotobacterium leiognathi conditions privacy policy protein sequence method involves putting general method applicable article journal evolutionary tree depicting recently diverged sequences accepting optional cookies johnson ms dendrogram problem posed california-san diego superoxide dismutase journal finder publish natural gene transfer mckay wm article log maximum parsimony method main content log coli ribosomal proteins molecular data sets multiple alignment article cite

Questions {โ“}

  • Doolittle RF (1981) Similar amino acid sequences: chance or common ancestry?
  • Leunissen JAM, De Jong WW (1986) Copper/zinc superoxide dismutase: how likely is gene transfer from ponyfish toPhotobacterium leiognathi?

Schema {๐Ÿ—บ๏ธ}

WebPage:
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         headline:Progressive sequence alignment as a prerequisitetto correct phylogenetic trees
         description:A progressive alignment method is described that utilizes the Needleman and Wunsch pairwise alignment algorithm iteratively to achieve the multiple alignment of a set of protein sequences and to construct an evolutionary tree depicting their relationship. The sequences are assumed a priori to share a common ancestor, and the trees are constructed from difference matrices derived directly from the multiple alignment. The thrust of the method involves putting more trust in the comparison of recently diverged sequences than in those evolved in the distant past. In particular, this rule is followed: โ€œonce a gap, always a gapโ€. The method has been applied to three sets of protein sequences: 7 superoxide dismutases, 11 globins, and 9 tyrosine kinase-like sequences. Multiple alignments and phylogenetic trees for these sets of sequences were determined and compared with trees derived by conventional pairwise treatments. In several instances, the progressive method led to trees that appeared to be more in line with biological expectations than were trees obtained by more commonly used methods.
         datePublished:
         dateModified:
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            Multiple sequence alignments
            Evolutionary trees
            Evolutionary Biology
            Microbiology
            Plant Sciences
            Plant Genetics and Genomics
            Animal Genetics and Genomics
            Cell Biology
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      headline:Progressive sequence alignment as a prerequisitetto correct phylogenetic trees
      description:A progressive alignment method is described that utilizes the Needleman and Wunsch pairwise alignment algorithm iteratively to achieve the multiple alignment of a set of protein sequences and to construct an evolutionary tree depicting their relationship. The sequences are assumed a priori to share a common ancestor, and the trees are constructed from difference matrices derived directly from the multiple alignment. The thrust of the method involves putting more trust in the comparison of recently diverged sequences than in those evolved in the distant past. In particular, this rule is followed: โ€œonce a gap, always a gapโ€. The method has been applied to three sets of protein sequences: 7 superoxide dismutases, 11 globins, and 9 tyrosine kinase-like sequences. Multiple alignments and phylogenetic trees for these sets of sequences were determined and compared with trees derived by conventional pairwise treatments. In several instances, the progressive method led to trees that appeared to be more in line with biological expectations than were trees obtained by more commonly used methods.
      datePublished:
      dateModified:
      pageStart:351
      pageEnd:360
      sameAs:https://doi.org/10.1007/BF02603120
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         Multiple sequence alignments
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         Microbiology
         Plant Sciences
         Plant Genetics and Genomics
         Animal Genetics and Genomics
         Cell Biology
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            name:Russell F. Doolittle
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