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Title:
The alignment of sets of sequences and the construction of phyletic trees: An integrated method | Journal of Molecular Evolution
Description:
In this paper we argue that the alignment of sets of sequences and the construction of phyletic trees cannot be treated separately. The concept of ‘good alignment’ is meaningless without reference to a phyletic tree, and the construction of phyletic trees presupposes alignment of the sequences. We propose an integrated method that generates both an alignment of a set of sequences and a phyletic tree. In this method a putative tree is used to align the sequences and the alignment obtained is used to adjust the tree; this process is iterated. As a demonstration we apply the method to the analysis of the evolution of 5S rRNA sequences in prokaryotes.
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Keywords {🔍}
google, scholar, article, sequences, sequence, pubmed, data, trees, alignment, tree, mol, phyletic, method, hogeweg, access, evol, privacy, cookies, content, analysis, journal, research, search, hesper, phylogenetic, evolutionary, acid, biol, information, publish, molecular, evolution, construction, phylogeny, methods, related, structure, amino, utrecht, log, sets, integrated, metrics, rrna, prokaryotes, biological, open, discover, blanken, klotz,
Topics {✒️}
5s rrna sequences month download article/chapter sequence homology sequence phylogeny research minimum length methods amino acid sequence related subjects biological sequence metrics molecular evolution aims rrna sequences distantly related species phenetic methods amino acid sequences privacy choices/manage cookies full article pdf check access instant access phyletic tree blanken rl estimated phylogenetic trees phylogenetic tree derived constructing evolutionary trees calculating evolutionary trees computer comparison phyletic trees european economic area scope submit manuscript zablen lb blakemore biological pattern analysis conditions privacy policy comparative biosequence metrics gene frequency data sequence data iterative character weighting molecular data ii accepting optional cookies plant biologists’ guide general method applicable waterman ms phylogenetic tree bioinformatic pattern analysis journal finder publish main content log article journal article hogeweg putative tree integrated method published klotz lc �good alignment alignment obtained
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headline:The alignment of sets of sequences and the construction of phyletic trees: An integrated method
description:In this paper we argue that the alignment of sets of sequences and the construction of phyletic trees cannot be treated separately. The concept of ‘good alignment’ is meaningless without reference to a phyletic tree, and the construction of phyletic trees presupposes alignment of the sequences. We propose an integrated method that generates both an alignment of a set of sequences and a phyletic tree. In this method a putative tree is used to align the sequences and the alignment obtained is used to adjust the tree; this process is iterated. As a demonstration we apply the method to the analysis of the evolution of 5S rRNA sequences in prokaryotes.
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keywords:
Sequence alignment
Phyletic trees
Matrix methods
Internode sequences
Homology assessment
Tree representation
Prokaryotic 5S rRNA evolution
Evolutionary Biology
Microbiology
Plant Sciences
Plant Genetics and Genomics
Animal Genetics and Genomics
Cell Biology
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headline:The alignment of sets of sequences and the construction of phyletic trees: An integrated method
description:In this paper we argue that the alignment of sets of sequences and the construction of phyletic trees cannot be treated separately. The concept of ‘good alignment’ is meaningless without reference to a phyletic tree, and the construction of phyletic trees presupposes alignment of the sequences. We propose an integrated method that generates both an alignment of a set of sequences and a phyletic tree. In this method a putative tree is used to align the sequences and the alignment obtained is used to adjust the tree; this process is iterated. As a demonstration we apply the method to the analysis of the evolution of 5S rRNA sequences in prokaryotes.
datePublished:
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pageStart:175
pageEnd:186
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Sequence alignment
Phyletic trees
Matrix methods
Internode sequences
Homology assessment
Tree representation
Prokaryotic 5S rRNA evolution
Evolutionary Biology
Microbiology
Plant Sciences
Plant Genetics and Genomics
Animal Genetics and Genomics
Cell Biology
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