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🌠 Phenomenal Traffic: 5M - 10M visitors per month


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Keywords {🔍}

doi, gbp, inflammasome, scholar, pubmed, google, gbps, pmc, article, free, activation, caspase, nlrp, human, proteins, infection, cell, immunity, lps, immunol, bacterial, host, noncanonical, ifninduced, defense, assembly, responses, protein, fig, nature, macrophages, asc, aim, science, binding, canonical, ifnγ, nat, cells, gramnegative, ilβ, bacteria, death, mice, gondii, gtpase, release, pathway, pyroptosis, type,

Topics {✒️}

γ-d-glutamyl-meso-diaminopimelic acid [dap] ifn-γ-induced cell-autonomous responses tak1-jnk signaling cascade ifn-γ-induced macrophage immunity tlr4-trif-irf3 circuit ifn-γ-activated human cells caspase-11-mediated il-1β secretion ifn-γ-activated human monocytes host-virus arms races nlrp3-dependent pro-il-18 cleavage autocrine ifn-β signaling nf-κb-dependent transcription n-terminal gtpase-domain bound c-terminal α-helices ifn-γ-induced upregulation ifn-γ-dependent effects c-terminal helical domains type ii ifn-γ sqstm1/p62/a170 regulates ifn-γ-activated macrophages ifn-induced gtpases mgbp1 c-terminal helical domain nucleic acid-sensing genes reduced serum il-1β gtpases undergo nucleotide-dependent ifn-inducible gtpase superfamily gbp-mediated pyroptotic clearance impaired serum il-1β ifn-gamma-inducible lrg-47 ifn-induced inflammasome proteins ifn-γ-induced expression ifn-induced transcriptional signals leucine-rich repeat [lrr] localize nearby irregularly-shaped tnf-alpha mediates sensitization heightens caspase-11-dependent responses undergo transition-state assembly ifn-induced intracellular killing caspase-11-dependent noncanonical pathway host-tropic evasion strategy20 murine guanylate-binding protein ifn-γ versus lps gbp-dependent inflammasome activation pmc beta search gbp-dependent inflammasome defects ifn-γ primes keratinocytes inflammasome-activating molecular component pamp-triggered activation threshold external gtpase-activating proteins zebrafish guanylate-binding protein

Questions {❓}

• How do the GBPs work?
• How do they confer their functions?

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• https://twitter.com/ncbi
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• https://www.linkedin.com/company/ncbinlm
• https://twitter.com/nlm_nih
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External Links {🔗}(197)

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