
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Genetic determinants of the gut microbiome in UK Twins - PMC
Description:
Studies in mice and humans have revealed intriguing associations between host genetics and the microbiome. Here we report a 16S rRNA-based analysis of the gut microbiome in 1,126 twin pairs, a subset of which was previously reported. Tripling the ...
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Keywords {π}
doi, google, scholar, pubmed, pmc, article, free, gene, taxa, association, gut, microbiome, genetic, heritability, heritable, host, human, studies, analysis, genes, twin, pvalue, figure, results, data, study, dataset, diet, nature, microbiota, snp, pairs, samples, associations, estimates, bifidobacterium, abundances, expression, genetics, genus, mice, mouse, twins, goodrich, davenport, lactase, formate, genomewide, sample, candidate,
Topics {βοΈ}
genome-wide trans-ancestry meta-analysis nci-seer case-control study long-chain fatty acids [google scholar] pesson 16s rrna-based analysis pmc beta search pre-mrna splicing signature 2Γ250bp paired-end sequencing gene-microbe associations uncovered gene/microbe links relate [google scholar] genome-wide manhattan plot van de merwe sanson-le pors mj akkermans-van vliet wm cyp1a1-cyp1a2 gene regions tissue-wide significance level immune-related genes uncovered sialic acid-binding immunoglobulin box-cox transformed abundances genome-wide association analyses gene-based association method 16s rrna gene european nucleotide archive beta-diversity distance matrices inter-individual genetic variation experimental procedures genome-wide association analysis study-wide significance threshold taxon genome-wide analysis genome-wide association studies genome-wide association study christensenellaceae-methanogen consortium regulates single nucleotide polymorphisms supplementary materials included de la grange host-gut microbiota interactions gut microbiome-related diseases gene-microbe links sanz-pamplona site-specific programming gene-microbe associations host-microbe interactions bray curtis dissimilarity defense acknowledgments nih ro1 dk093595 nex-generation sequencing genome-wide analysis sequence based results mabel beckman foundation
Questions {β}
- Does host gentoype shape the microbiome?
- Implications for Crohnβs disease?
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