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Title[redir]:
Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance - PMC
Description:
During the last three decades, 4-hydroxy-2-nonenal (HNE), a major α,β-unsaturated aldehyde product of n-6 fatty acid oxidation, has been shown to be involved in a great number of pathologies such as metabolic diseases, neurodegenerative diseases and ...
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Keywords {🔍}
doi, hne, cell, pubmed, google, scholar, cells, apoptosis, death, stress, free, hydroxynonenal, oxidative, protein, pmc, article, lipid, proteins, pathway, cancer, activation, levels, human, peroxidation, induction, factor, biol, mitochondrial, detoxification, expression, med, diseases, nrf, product, hneinduced, jnk, formation, fas, activity, role, signaling, adducts, antioxidant, pathways, cellular, ros, induces, cycle, radic, res,
Topics {✒️}
tnf-related apoptosis-inducing ligand omi/htra2 prevents xiap x-linked iap rat aldo-keto reductase b-cell lymphoma 2 retinoblastoma protein aldo-keto reductase thioredoxin reductase 1 pufa content vascular smooth-muscle cells 4-hydroxynonenoïc acid tnf tgfβ apoptosis-inducing factor c-jun n-terminal kinase tumor necrosis factor reactive oxygen species death-inducing signaling complex unfolded protein response fatty acid synthesis lysosomal membrane permeabilization glutathione s-transferase a4-4 fas-activated serine/threonine kinase β-unsaturated aldehyde product cell cycle division smooth muscle cells vsmc exhibit cyclin-dependent kinase heat shock proteins jnk-c-jun/ap-1 pathway β-unsaturated aldehyde 4-hydroxynonenal multidrug-resistant protein fas ligand apoptosis-inducing concentrations apoptosis protease-activating factor-1 hne-modified amyloid β-peptides modified low-density lipoproteins hdac inhibitor panobinostat heme oxygenase 1 vsmc thioredoxin-1 pdgfr trail cyclin-dependent kinases inhibitors inducing er stress c-jun/ap-1 signaling plasma low-density lipoproteins glutathione s-transferase glutathione-s-transferase hle b-3 cells
Questions {❓}
- How do the detoxification pathways modulate the cell fate upon HNE exposure?
- Upon HNE exposure, what are the processes to avoid death?
- What are the mechanisms of cell death induced by HNE?
- What is the relative importance of the canonical apoptotic pathways compared with atypical cell deaths in HNE-exposed cells?
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- Revenue of https://doi.org/10.1016/j.abb.2008.09.016
- How much does https://scholar.google.com/scholar_lookup?journal=Arch%20Biochem%20Biophys&title=4-Hydroxynonenal%20induces%20p53-mediated%20apoptosis%20in%20retinal%20pigment%20epithelial%20cells&author=A%20Sharma&author=R%20Sharma&author=P%20Chaudhary&author=R%20Vatsyayan&author=V%20Pearce&volume=480&publication_year=2008&pages=85-94&pmid=18930016&doi=10.1016/j.abb.2008.09.016& net monthly?
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- How much does https://scholar.google.com/scholar_lookup?journal=Free%20Radic%20Biol%20Med&title=Cellular%20lipid%20peroxidation%20end-products%20induce%20apoptosis%20in%20human%20lens%20epithelial%20cells&author=S%20Choudhary&author=W%20Zhang&author=F%20Zhou&author=GA%20Campbell&author=LL%20Chan&volume=32&publication_year=2002&pages=360-369&pmid=11841926&doi=10.1016/s0891-5849(01)00810-3& bring in each month?
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- https://doi.org/10.1074/jbc.M111.320416's total income per month
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- How much profit does https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&title=Heat%20shock%20factor%201%20attenuates%204-hydroxynonenal-mediated%20apoptosis:%20critical%20role%20for%20heat%20shock%20protein%2070%20induction%20and%20stabilization%20of%20Bcl-XL&author=AT%20Jacobs&author=LJ%20Marnett&volume=282&publication_year=2007&pages=33412-33420&pmid=17873279&doi=10.1074/jbc.M706799200& generate?
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- What are the total earnings of https://www.hhs.gov/vulnerability-disclosure-policy/index.html?
- https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Ajournal income
- What's the financial outcome of https://www.nlm.nih.gov/accessibility.html?
- Profit of https://www.nlm.nih.gov/careers/careers.html
- How profitable is https://www.nlm.nih.gov/?
- Find out how much https://www.nih.gov/ earns monthly
- How much does https://www.hhs.gov/ generate monthly?
- How much does https://www.usa.gov/ net monthly?
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi