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We began analyzing https://pnas.org/doi/full/10.1073/pnas.172398899, but it redirected us to https://pnas.org/doi/full/10.1073/pnas.172398899. The analysis below is for the second page.
Title[redir]:
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants | PNAS
Description:
Coordinate induction of phase 2 proteins and elevation of glutathione protect cells against the toxic and carcinogenic effects of electrophiles and oxidants. All inducers react covalently with thio...
Title[redir]:
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants | PNAS
Description:
Coordinate induction of phase 2 proteins and elevation of glutathione protect cells against the toxic and carcinogenic effects of electrophiles and oxidants. All inducers react covalently with thio...
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Keywords {๐}
keap, inducers, crossref, nrf, reaction, google, scholar, pubmed, cysteine, protein, phase, sciences, thiol, peptides, groups, disulfide, residues, inducer, hba, sulforaphane, department, center, fig, neh, dipyridyl, university, tsukuba, domain, reactive, talalay, cysteines, added, institute, proteins, transcription, molecular, dexmes, hdexmes, gel, johns, hopkins, cancer, medical, view, mass, binding, triscl, dtt, research, article,
Topics {โ๏ธ}
discussion direct demonstration social media facebook authors affiliations albena experimental procedures isopropyl ฮฒ-d-thiogalactoside emotions emotions coordinate ab-mass spectrometry facility full-length cdna copy ฮฑ-methylene-ฮณ-butyrolactone jan-willem van ittersum dex-mes-labeled cysteine residues unlike wild-type controls references 1 25 mm tris-cl/2 100 mm tris-cl 10 mm tris-cl valuable editorial consultation results purification flight mass spectrometry maltose-binding protein showed [3h]dex-mes bound applied biosystems/mds sciex dorothy cullman foundation current emotional state [3h]dex-mes binding sophisticated auditoryโmotor learning plasmid pet-15b-neh2 citation information michael reaction acceptors keap1-pyridyl mixed disulfide thioredoxin reductase/thioredoxin operon tris-cl buffer abbreviations dex-mes-modified cysteine dex-mes-labeled keap1 ion-exchange chromatography share librarian recommend pnas actin-bound protein keap1 keap1โnrf2 interaction resembles johns hopkins school download pdf collision-induced dissociation acquisitions pnas highlights newsletter dex-mes-modified cysteines antioxidant response element crude supernatant fraction high uv absorption related individual variability johns hopkins fund
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