
NCBI . NLM . NIH . GOV {
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Title[redir]:
Epithelialâmesenchymal plasticity in carcinoma metastasis - PMC
Description:
A developmental program termed epithelialâmesenchymal transition (EMT) plays a critical role in promoting metastasis in epithelial-derived carcinomas. Recent studies also implicate its reverse program, mesenchymalâepithelial transition (MET), in ...
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Keywords {đ}
emt, cells, tumor, pubmed, google, scholar, doi, cancer, cell, pmc, metastasis, article, free, breast, epithelial, transition, expression, epithelialmesenchymal, ecadherin, program, studies, snail, carcinoma, twist, mesenchymal, ctcs, metastatic, res, invasion, activation, role, transcription, step, found, human, patients, tumors, promote, zeb, distant, molecular, markers, biol, extravasation, colonization, yang, progression, factors, formation, core,
Topics {âď¸}
wnt/β-catenin/lef-1 signaling pathway tgf-β-induced epithelialâmesenchymal transition e-cadherin-mediated adherens junctions double-negative feedback loop mda-mb-435s cells disease-free survival rate membrane-bound mt1-mmp pmc beta search mesenchymal mda-mb-231 cells basic helixâloopâhelix gsk-3β-mediated phosphorylation antagonizing p53-mediated apoptosis small-cell lung carcinoma e-cadherin gene nonsense t-cell-based immunotherapy tgf-β secretion solely e-cadherin repressors zeb1 abd el-rehim dm tgf-β/smad signaling epithelialâmesenchymal transition defines e-cadherin-positive areas repressing sec23a-mediated secretion epithelialâmesenchymal-transitioned cells cellâmatrix contact points epithelialâmesenchymal transition induced nf-Îşb p65 activation e-cadherin gene mutations suppress e-cadherin transcription specific emt-inducing signals represses e-cadherin expression additional met-inducing signals inflammation-induced cell migration e-cadherin-positive cells sip1/zeb2 induces emt maintain apicalâbasal polarity chromosome-unstable colorectal tumors epithelialâmesenchymal transition markers e-cadherin gene expression emt-inducing signals tend mirna-200 family expression disrupting cellâcell junctions key rate-limiting step footnotes article regulate epithelialâmesenchymal transitions Îł-catenin protein expression progression-free survival repressing e-cadherin expression real-time quantitative pcr additional genetic/epigenetic alterations tgf-β pathway appears
Questions {â}
- In other words: Is the absence of an EMT-inducing signal sufficient for EMT reversion?
- Why do tumor cells need to revert to an epithelial state to grow into macrometastases?
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- Monthly income for https://doi.org/10.1158/0008-5472.CAN-08-1444
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- Earnings of https://doi.org/10.1016/j.ccr.2004.09.033
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- How much does https://scholar.google.com/scholar_lookup?journal=Genes%20Dev&title=Snail%20blocks%20the%20cell%20cycle%20and%20confers%20resistance%20to%20cell%20death&author=S%20Vega&author=AV%20Morales&author=OH%20Ocana&author=F%20Valdes&author=I%20Fabregat&volume=18&publication_year=2004&pages=1131-1143&pmid=15155580&doi=10.1101/gad.294104& net monthly?
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- How much revenue does https://scholar.google.com/scholar_lookup?journal=Clin%20Cancer%20Res&title=Isolation%20and%20molecular%20profiling%20of%20bone%20marrow%20micrometastases%20identifies%20TWIST1%20as%20a%20marker%20of%20early%20tumor%20relapse%20in%20breast%20cancer%20patients&author=MA%20Watson&author=LR%20Ylagan&author=KM%20Trinkaus&author=WE%20Gillanders&author=MJ%20Naughton&volume=13&publication_year=2007&pages=5001-5009&pmid=17785550&doi=10.1158/1078-0432.CCR-07-0024& produce monthly?
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- How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Twist,%20a%20master%20regulator%20of%20morphogenesis,%20plays%20an%20essential%20role%20in%20tumor%20metastasis&author=J%20Yang&author=SA%20Mani&author=JL%20Donaher&author=S%20Ramaswamy&author=RA%20Itzykson&volume=117&publication_year=2004&pages=927-939&pmid=15210113&doi=10.1016/j.cell.2004.06.006& make?
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- What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Clin%20Cancer%20Res&title=Chronic%20oxaliplatin%20resistance%20induces%20epithelial-to-mesenchymal%20transition%20in%20colorectal%20cancer%20cell%20lines&author=AD%20Yang&author=F%20Fan&author=ER%20Camp&author=G%20van%20Buren&author=W%20Liu&volume=12&publication_year=2006&pages=4147-4153&pmid=16857785&doi=10.1158/1078-0432.CCR-06-0038&?
- How much income is https://doi.org/10.1038/ncb1691 earning monthly?
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