
NATURE . COM {
}
Title:
The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival | Oncogene
Description:
The type I insulin-like growth factor receptor (IGF1R) regulates multiple aspects of malignancy and is the target of several drugs currently in clinical trials. Although the function of IGF1R in proliferation and survival is well studied, the regulation of metastasis by IGF1R is not as clearly delineated. Previous work showed that disruption of IGF1R signaling by overexpression of a dominant-negative IGF1R inhibited metastasis. To establish a clinically applicable approach to inhibition of metastasis by targeting IGF1R, we examined the effect of an inhibitory antibody against IGF1R, EM164 and its humanized version, AVE1642, on metastasis of cancer cells. EM164 and AVE1642 did not affect primary tumor growth of MDA-435A/LCC6 cells but inhibited metastasis of these cells. Consistent with this inhibition in the formation of metastatic nodules, disruption of IGF1R also resulted in a decreased number of circulating tumor cells in blood of tumor-bearing mice. Disruption of IGF1R with a dominant-negative construct or antibody inhibited invasion across Matrigel in vitro. When tumor cells were directly injected into the circulation through the lateral tail vein of mice, IGF1R disruption also resulted in significant reduction of pulmonary nodules, suggesting that regulation of invasion is not the only function of IGF1R signaling. Further, disruption of IGF1R rendered cells more susceptible to anoikis. Thus, IGF1R regulated metastasis independently of tumor growth. The multiple phenotypes regulated by IGF1R must be considered during development of this therapeutic strategy as inhibition of metastasis independent of inhibition of tumor growth is not easily assessed in phase II clinical trials.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Education
- Science
- Health & Fitness
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$63,100 per month
Our estimates place Nature.com's monthly online earnings from display ads at $42,042 to $115,616.
Keywords {π}
cancer, pubmed, article, google, scholar, growth, cas, receptor, insulinlike, metastasis, breast, factor, cells, nature, igfr, cell, res, tumor, antibody, human, yee, access, type, oncogene, sachdev, insulin, zhang, signaling, factori, central, clin, content, invasion, cookies, survival, metastatic, monoclonal, inhibits, tumors, privacy, disruption, inhibition, open, igf, therapy, vivo, irs, biol, research, usa,
Topics {βοΈ}
nature portfolio permissions reprints privacy policy pi3-kinase/akt pathway brendan melanoma research advertising nature 204 nature 227 nature 436 nature 410 nature social media author information authors isotype-matched control antibody ampk/erk-dependent growth author correspondence mda-435a/lcc6 cells springerlink instant access personal data mda-mb-435 cells bone-seeking clone exhibits preclinical model driven igf-ir kinase data protection permissions nih r01 ca074285 masonic cancer center regulates multiple aspects li sl human cancer cells minn aj human breast cancer recent development breast cancer cells dominant negative mutant chambers af potential cancer therapy circulating tumor cells dominant-negative construct breast cancer metastasis privacy refractory solid tumors single-chain antibodies prostate cancer tumors igf-1rΞ²/akt article sachdev tumor progression brain-seeking clone national cancer institute growth factor therapy
Questions {β}
- Is cancer a disease of self-seeding?
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
description:The type I insulin-like growth factor receptor (IGF1R) regulates multiple aspects of malignancy and is the target of several drugs currently in clinical trials. Although the function of IGF1R in proliferation and survival is well studied, the regulation of metastasis by IGF1R is not as clearly delineated. Previous work showed that disruption of IGF1R signaling by overexpression of a dominant-negative IGF1R inhibited metastasis. To establish a clinically applicable approach to inhibition of metastasis by targeting IGF1R, we examined the effect of an inhibitory antibody against IGF1R, EM164 and its humanized version, AVE1642, on metastasis of cancer cells. EM164 and AVE1642 did not affect primary tumor growth of MDA-435A/LCC6 cells but inhibited metastasis of these cells. Consistent with this inhibition in the formation of metastatic nodules, disruption of IGF1R also resulted in a decreased number of circulating tumor cells in blood of tumor-bearing mice. Disruption of IGF1R with a dominant-negative construct or antibody inhibited invasion across Matrigel in vitro. When tumor cells were directly injected into the circulation through the lateral tail vein of mice, IGF1R disruption also resulted in significant reduction of pulmonary nodules, suggesting that regulation of invasion is not the only function of IGF1R signaling. Further, disruption of IGF1R rendered cells more susceptible to anoikis. Thus, IGF1R regulated metastasis independently of tumor growth. The multiple phenotypes regulated by IGF1R must be considered during development of this therapeutic strategy as inhibition of metastasis independent of inhibition of tumor growth is not easily assessed in phase II clinical trials.
datePublished:2009-10-19T00:00:00Z
dateModified:2009-10-19T00:00:00Z
pageStart:251
pageEnd:262
sameAs:https://doi.org/10.1038/onc.2009.316
keywords:
cancer metastasis
type I IGF receptor
antibodies against IGF1R
invasion
circulating tumor cells
survival
Medicine/Public Health
general
Internal Medicine
Cell Biology
Human Genetics
Oncology
Apoptosis
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig7_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig8_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig9_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig10_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig11_HTML.jpg
isPartOf:
name:Oncogene
issn:
1476-5594
0950-9232
volumeNumber:29
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:D Sachdev
affiliation:
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:X Zhang
affiliation:
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
type:Person
name:I Matise
affiliation:
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:University of Minnesota
address:
name:Department of Veterinary Clinical Sciences, University of Minnesota, St Paul, USA
type:PostalAddress
type:Organization
type:Person
name:M Gaillard-Kelly
affiliation:
name:sanofi-aventis
address:
name:sanofi-aventis, Antony, France
type:PostalAddress
type:Organization
type:Person
name:D Yee
affiliation:
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
description:The type I insulin-like growth factor receptor (IGF1R) regulates multiple aspects of malignancy and is the target of several drugs currently in clinical trials. Although the function of IGF1R in proliferation and survival is well studied, the regulation of metastasis by IGF1R is not as clearly delineated. Previous work showed that disruption of IGF1R signaling by overexpression of a dominant-negative IGF1R inhibited metastasis. To establish a clinically applicable approach to inhibition of metastasis by targeting IGF1R, we examined the effect of an inhibitory antibody against IGF1R, EM164 and its humanized version, AVE1642, on metastasis of cancer cells. EM164 and AVE1642 did not affect primary tumor growth of MDA-435A/LCC6 cells but inhibited metastasis of these cells. Consistent with this inhibition in the formation of metastatic nodules, disruption of IGF1R also resulted in a decreased number of circulating tumor cells in blood of tumor-bearing mice. Disruption of IGF1R with a dominant-negative construct or antibody inhibited invasion across Matrigel in vitro. When tumor cells were directly injected into the circulation through the lateral tail vein of mice, IGF1R disruption also resulted in significant reduction of pulmonary nodules, suggesting that regulation of invasion is not the only function of IGF1R signaling. Further, disruption of IGF1R rendered cells more susceptible to anoikis. Thus, IGF1R regulated metastasis independently of tumor growth. The multiple phenotypes regulated by IGF1R must be considered during development of this therapeutic strategy as inhibition of metastasis independent of inhibition of tumor growth is not easily assessed in phase II clinical trials.
datePublished:2009-10-19T00:00:00Z
dateModified:2009-10-19T00:00:00Z
pageStart:251
pageEnd:262
sameAs:https://doi.org/10.1038/onc.2009.316
keywords:
cancer metastasis
type I IGF receptor
antibodies against IGF1R
invasion
circulating tumor cells
survival
Medicine/Public Health
general
Internal Medicine
Cell Biology
Human Genetics
Oncology
Apoptosis
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig6_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig7_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig8_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig9_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig10_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2009.316/MediaObjects/41388_2010_Article_BFonc2009316_Fig11_HTML.jpg
isPartOf:
name:Oncogene
issn:
1476-5594
0950-9232
volumeNumber:29
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:D Sachdev
affiliation:
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:X Zhang
affiliation:
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
type:Person
name:I Matise
affiliation:
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:University of Minnesota
address:
name:Department of Veterinary Clinical Sciences, University of Minnesota, St Paul, USA
type:PostalAddress
type:Organization
type:Person
name:M Gaillard-Kelly
affiliation:
name:sanofi-aventis
address:
name:sanofi-aventis, Antony, France
type:PostalAddress
type:Organization
type:Person
name:D Yee
affiliation:
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Oncogene
issn:
1476-5594
0950-9232
volumeNumber:29
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
name:University of Minnesota
address:
name:Department of Veterinary Clinical Sciences, University of Minnesota, St Paul, USA
type:PostalAddress
name:sanofi-aventis
address:
name:sanofi-aventis, Antony, France
type:PostalAddress
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:D Sachdev
affiliation:
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
email:[email protected]
name:X Zhang
affiliation:
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:I Matise
affiliation:
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:University of Minnesota
address:
name:Department of Veterinary Clinical Sciences, University of Minnesota, St Paul, USA
type:PostalAddress
type:Organization
name:M Gaillard-Kelly
affiliation:
name:sanofi-aventis
address:
name:sanofi-aventis, Antony, France
type:PostalAddress
type:Organization
name:D Yee
affiliation:
name:University of Minnesota
address:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
name:Masonic Cancer Center, University of Minnesota
address:
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
type:PostalAddress
type:Organization
PostalAddress:
name:Department of Medicine, University of Minnesota, Minneapolis, USA
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
name:Department of Veterinary Clinical Sciences, University of Minnesota, St Paul, USA
name:sanofi-aventis, Antony, France
name:Department of Medicine, University of Minnesota, Minneapolis, USA
name:Masonic Cancer Center, University of Minnesota, Minneapolis, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {π}(175)
- How profitable is https://link.springer.com/article/10.1038/onc.2009.316?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
- What's the revenue for https://doi.org/10.1016%2Fj.ccr.2004.06.010?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15261139 make?
- What's the income of http://scholar.google.com/scholar_lookup?&title=Molecular%20characterization%20of%20the%20tumor%20microenvironment%20in%20breast%20cancer&journal=Cancer%20Cell&doi=10.1016%2Fj.ccr.2004.06.010&volume=6&pages=17-32&publication_year=2004&author=Allinen%2CM&author=Beroukhim%2CR&author=Cai%2CL&author=Brennan%2CC&author=Lahti-Domenici%2CJ&author=Huang%2CH?
- Find out how much https://doi.org/10.1517%2F14728222.9.4.753 earns monthly
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16083341's financial summary
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=The%20insulin-like%20growth%20factor-I%20receptor%20as%20a%20target%20for%20cancer%20therapy&journal=Expert%20Opin%20Ther%20Targets&doi=10.1517%2F14728222.9.4.753&volume=9&pages=753-768&publication_year=2005&author=Baserga%2CR
- Earnings of https://doi.org/10.1038%2F204793a0
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14235685?
- http://scholar.google.com/scholar_lookup?&title=Separation%20of%20white%20blood%20cells&journal=Nature&doi=10.1038%2F204793a0&volume=204&pages=793-794&publication_year=1964&author=Boyum%2CA income
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14695208 generate?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=A%20fully%20human%20monoclonal%20antibody%20to%20the%20insulin-like%20growth%20factor%20I%20receptor%20blocks%20ligand-dependent%20signaling%20and%20inhibits%20human%20tumor%20growth%20in%20vivo&journal=Cancer%20Res&volume=63&pages=8912-8921&publication_year=2003&author=Burtrum%2CD&author=Zhu%2CZ&author=Lu%2CD&author=Anderson%2CDM&author=Prewett%2CM&author=Pereira%2CDS?
- What's the financial intake of https://doi.org/10.1038%2Fsj.bjc.6603354?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17043687's revenue stream
- How much income does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2360584 have?
- How much does http://scholar.google.com/scholar_lookup?&title=Insulin%20receptor%20substrates%20mediate%20distinct%20biological%20responses%20to%20insulin-like%20growth%20factor%20receptor%20activation%20in%20breast%20cancer%20cells&journal=Br%20J%20Cancer&doi=10.1038%2Fsj.bjc.6603354&volume=95&pages=1220-1228&publication_year=2006&author=Byron%2CSA&author=Horwitz%2CKB&author=Richer%2CJK&author=Lange%2CCA&author=Zhang%2CX&author=Yee%2CD pull in monthly?
- How much revenue does https://doi.org/10.1038%2Fnrc865 generate?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12154349 produce monthly?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Dissemination%20and%20growth%20of%20cancer%20cells%20in%20metastatic%20sites&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc865&volume=2&pages=563-572&publication_year=2002&author=Chambers%2CAF&author=Groom%2CAC&author=MacDonald%2CIC?
- How much revenue does https://doi.org/10.1158%2F1078-0432.CCR-04-1070 bring in?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15756033's financial summary
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Combination%20therapy%20enhances%20the%20inhibition%20of%20tumor%20growth%20with%20the%20fully%20human%20anti-type%201%20insulin-like%20growth%20factor%20receptor%20monoclonal%20antibody%20CP-751%E2%80%89871&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-04-1070&volume=11&pages=2063-2073&publication_year=2005&author=Cohen%2CBD&author=Baker%2CDA&author=Soderstrom%2CC&author=Tkalcevic%2CG&author=Rossi%2CAM&author=Miller%2CPE
- https://doi.org/10.1128%2FMCB.00260-06's revenue stream
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17030631
- What are the earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698542?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Mammary%20tumorigenesis%20and%20metastasis%20caused%20by%20overexpression%20of%20insulin%20receptor%20substrate%201%20%28IRS-1%29%20or%20IRS-2&journal=Mol%20Cell%20Biol&doi=10.1128%2FMCB.00260-06&volume=26&pages=9302-9314&publication_year=2006&author=Dearth%2CRK&author=Cui%2CX&author=Kim%2CHJ&author=Kuiatse%2CI&author=Lawrence%2CNA&author=Zhang%2CX
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9699666?
- How much does http://scholar.google.com/scholar_lookup?&title=A%20dominant%20negative%20mutant%20of%20the%20insulin-like%20growth%20factor-I%20receptor%20inhibits%20the%20adhesion%2C%20invasion%2C%20and%20metastasis%20of%20breast%20cancer&journal=Cancer%20Res&volume=58&pages=3353-3361&publication_year=1998&author=Dunn%2CSE&author=Ehrlich%2CM&author=Sharp%2CNJ&author=Reiss%2CK&author=Solomon%2CG&author=Hawkins%2CR pull in?
- Earnings of https://doi.org/10.1016%2FS1535-6108%2804%2900051-0
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15050915
- How much does http://scholar.google.com/scholar_lookup?&title=in%20vivo%20antitumor%20activity%20of%20NVP-AEW541-A%20novel%2C%20potent%2C%20and%20selective%20inhibitor%20of%20the%20IGF-IR%20kinase&journal=Cancer%20Cell&doi=10.1016%2FS1535-6108%2804%2900051-0&volume=5&pages=231-239&publication_year=2004&author=Garcia-Echeverria%2CC&author=Pearson%2CMA&author=Marti%2CA&author=Meyer%2CT&author=Mestan%2CJ&author=Zimmermann%2CJ net monthly?
- How much does https://doi.org/10.4161%2Fcc.6.6.3987 gross monthly?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17361103
- How much profit does http://scholar.google.com/scholar_lookup?&title=Divergent%20roles%20for%20IRS-1%20and%20IRS-2%20in%20breast%20cancer%20metastasis&journal=Cell%20Cycle&doi=10.4161%2Fcc.6.6.3987&volume=6&pages=631-637&publication_year=2007&author=Gibson%2CSL&author=Ma%2CZ&author=Shaw%2CLM generate?
- https://doi.org/10.1016%2Fj.cell.2006.11.001's total income per month
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17110329?
- How much does http://scholar.google.com/scholar_lookup?&title=Cancer%20metastasis%3A%20building%20a%20framework&journal=Cell&doi=10.1016%2Fj.cell.2006.11.001&volume=127&pages=679-695&publication_year=2006&author=Gupta%2CGP&author=Massague%2CJ pull in?
- Explore the financials of https://doi.org/10.1101%2Fsqb.2005.70.018
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16869748?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Identifying%20site-specific%20metastasis%20genes%20and%20functions&journal=Cold%20Spring%20Harb%20Symp%20Quant%20Biol&doi=10.1101%2Fsqb.2005.70.018&volume=70&pages=149-158&publication_year=2005&author=Gupta%2CGP&author=Minn%2CAJ&author=Kang%2CY&author=Siegel%2CPM&author=Serganova%2CI&author=Cordon-Cardo%2CC
- Revenue of https://doi.org/10.1158%2F0008-5472.CAN-05-1107
- How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16397250 have?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=in%20vitro%20and%20in%20vivo%20antitumor%20effects%20of%20the%20dual%20insulin-like%20growth%20factor-I%2Finsulin%20receptor%20inhibitor%2C%20BMS-554417&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-05-1107&volume=66&pages=362-371&publication_year=2006&author=Haluska%2CP&author=Carboni%2CJM&author=Loegering%2CDA&author=Lee%2CFY&author=Wittman%2CM&author=Saulnier%2CMG?
- Learn about the earnings of https://doi.org/10.1158%2F1078-0432.CCR-07-1118
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17908976 gross monthly?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Phase%20I%20dose%20escalation%20study%20of%20the%20anti%20insulin-like%20growth%20factor-I%20receptor%20monoclonal%20antibody%20CP-751%E2%80%89871%20in%20patients%20with%20refractory%20solid%20tumors&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-07-1118&volume=13&pages=5834-5840&publication_year=2007&author=Haluska%2CP&author=Shaw%2CHM&author=Batzel%2CGN&author=Yin%2CD&author=Molina%2CJR&author=Molife%2CLR?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=A%20phase%20I%2C%20first%20in%20human%20study%20of%20weekly%20IMC-A12%2C%20a%20human%20insulin%20like%20growth%20factor-I%20receptor%20IgG1%20monoclonal%20antibody%2C%20in%20patients%20with%20advanced%20solid%20tumors&journal=J%20Clin%20Oncology&volume=25%20%28No%2018S%29&publication_year=2007&author=Higano%2CCS&author=Yu%2CEY&author=Whiting%2CSH&author=Gordon%2CMS&author=LoRusso%2CP&author=Fox%2CF?
- How much cash flow does https://doi.org/10.1074%2Fjbc.273.16.9994 have monthly?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9545345?
- How much does http://scholar.google.com/scholar_lookup?&title=Insulin%20receptor%20substrate-1%20is%20the%20predominant%20signaling%20molecule%20activated%20by%20insulin-like%20growth%20factor-I%2C%20insulin%2C%20and%20interleukin-4%20in%20estrogen%20receptor-positive%20human%20breast%20cancer%20cells&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.273.16.9994&volume=273&pages=9994-10003&publication_year=1998&author=Jackson%2CJG&author=White%2CMF&author=Yee%2CD bring in each month?
- Learn how profitable https://doi.org/10.1038%2Fsj.onc.1204920 is on a monthly basis
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11704861 each month?
- Profit of http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20breast%20cancer%20cell%20motility%20by%20insulin%20receptor%20substrate-2%20%28IRS-2%29%20in%20metastatic%20variants%20of%20human%20breast%20cancer%20cell%20lines&journal=Oncogene&doi=10.1038%2Fsj.onc.1204920&volume=20&pages=7318-7325&publication_year=2001&author=Jackson%2CJG&author=Zhang%2CX&author=Yoneda%2CT&author=Yee%2CD
- https://doi.org/10.1016%2FS1535-6108%2803%2900132-6 income
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12842083
- http://scholar.google.com/scholar_lookup?&title=A%20multigenic%20program%20mediating%20breast%20cancer%20metastasis%20to%20bone&journal=Cancer%20Cell&doi=10.1016%2FS1535-6108%2803%2900132-6&volume=3&pages=537-549&publication_year=2003&author=Kang%2CY&author=Siegel%2CPM&author=Shu%2CW&author=Drobnjak%2CM&author=Kakonen%2CSM&author=Cordon-Cardo%2CC's financial summary
- How much money does http://scholar.google.com/scholar_lookup?&title=Efficacy%20of%20the%20anti-insulin%20like%20growth%20factor%20I%20receptor%20%28IGF-IR%29%20antibody%20CP%20751%20871%20in%20combination%20with%20paclitaxel%20and%20carboplatin%20as%20first-line%20treatment%20for%20advanced%20non-small%20cell%20lung%20cancer%20%28NSCLC%29&journal=J%20Clin%20Oncology&volume=25%20%28No%2018S%29&publication_year=2007&author=Karp%2CDD&author=Paz-Ares%2CLG&author=Blakely%2CLJ&author=Kreisman%2CH&author=Cohen%2CRB&author=Langer%2CCJ make?
- What are the total earnings of https://doi.org/10.1038%2F227680a0?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=5432063 generate monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Cleavage%20of%20structural%20proteins%20during%20the%20assembly%20of%20the%20head%20of%20bacteriophage%20T4&journal=Nature&doi=10.1038%2F227680a0&volume=227&pages=680-685&publication_year=1970&author=Laemmli%2CUK gross monthly?
- Profit of https://doi.org/10.1038%2Fbjc.1996.29
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8546900
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074305 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=MDA435%2FLCC6%20and%20MDA435%2FLCC6%28MDR1%29%3A%20ascites%20models%20of%20human%20breast%20cancer&journal=Br%20J%20Cancer&doi=10.1038%2Fbjc.1996.29&volume=73&pages=154-161&publication_year=1996&author=Leonessa%2CF&author=Green%2CD&author=Licht%2CT&author=Wright%2CA&author=Wingatelegette%2CK&author=Lippman%2CJ rake in every month?
- Get to know https://link.springer.com/doi/10.1007/s002620000115's earnings
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10941907 each month?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Single-chain%20antibodies%20against%20human%20insulin-like%20growth%20factor%20I%20receptor%3A%20expression%2C%20purification%2C%20and%20effect%20on%20tumor%20growth&journal=Cancer%20Immunol%20Immunother&doi=10.1007%2Fs002620000115&volume=49&pages=243-252&publication_year=2000&author=Li%2CSL&author=Liang%2CSJ&author=Guo%2CN&author=Wu%2CAM&author=Fujita-Yamaguchi%2CY
- What's https://doi.org/10.1016%2FS1535-6108%2802%2900055-7's gross income?
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12086849
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Elevated%20levels%20of%20IGF-1%20receptor%20convey%20invasive%20and%20metastatic%20capability%20in%20a%20mouse%20model%20of%20pancreatic%20islet%20tumorigenesis&journal=Cancer%20Cell&doi=10.1016%2FS1535-6108%2802%2900055-7&volume=1&pages=339-353&publication_year=2002&author=Lopez%2CT&author=Hanahan%2CD each month?
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12941837
- Monthly income for http://scholar.google.com/scholar_lookup?&title=An%20anti-insulin-like%20growth%20factor%20I%20receptor%20antibody%20that%20is%20a%20potent%20inhibitor%20of%20cancer%20cell%20proliferation&journal=Cancer%20Res&volume=63&pages=5073-5083&publication_year=2003&author=Maloney%2CEK&author=McLaughlin%2CJL&author=Dagdigian%2CNE&author=Garrett%2CLM&author=Connors%2CKM&author=Zhou%2CXM
- Find out how much https://doi.org/10.1038%2Fnature03799 earns monthly
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16049480?
- Check the income stats for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283098
- How much does http://scholar.google.com/scholar_lookup?&title=Genes%20that%20mediate%20breast%20cancer%20metastasis%20to%20lung&journal=Nature&doi=10.1038%2Fnature03799&volume=436&pages=518-524&publication_year=2005&author=Minn%2CAJ&author=Gupta%2CGP&author=Siegel%2CPM&author=Bos%2CPD&author=Shu%2CW&author=Giri%2CDD earn?
- What's the monthly income of https://doi.org/10.1172%2FJCI22320?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15630443 generate monthly?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539194 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Distinct%20organ-specific%20metastatic%20potential%20of%20individual%20breast%20cancer%20cells%20and%20primary%20tumors&journal=J%20Clin%20Invest&doi=10.1172%2FJCI22320&volume=115&pages=44-55&publication_year=2005&author=Minn%2CAJ&author=Kang%2CY&author=Serganova%2CI&author=Gupta%2CGP&author=Giri%2CDD&author=Doubrovin%2CM gross monthly?
- How much profit does https://doi.org/10.1038%2F35065016 generate?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11242036 net monthly?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Involvement%20of%20chemokine%20receptors%20in%20breast%20cancer%20metastasis&journal=Nature&doi=10.1038%2F35065016&volume=410&pages=50-56&publication_year=2001&author=Muller%2CA&author=Homey%2CB&author=Soto%2CH&author=Ge%2CN&author=Catron%2CD&author=Buchanan%2CME making per month?
- How much does https://doi.org/10.1128%2FMCB.24.22.9726-9735.2004 pull in monthly?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15509777 make?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525494?
- How much income does http://scholar.google.com/scholar_lookup?&title=Involvement%20of%20insulin%20receptor%20substrate%202%20in%20mammary%20tumor%20metastasis&journal=Mol%20Cell%20Biol&doi=10.1128%2FMCB.24.22.9726-9735.2004&volume=24&pages=9726-9735&publication_year=2004&author=Nagle%2CJA&author=Ma%2CZ&author=Byrne%2CMA&author=White%2CMF&author=Shaw%2CLM have?
- What's the monthly money flow for https://doi.org/10.1038%2Fnm0806-875?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16892025?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Is%20cancer%20a%20disease%20of%20self-seeding%3F&journal=Nat%20Med&doi=10.1038%2Fnm0806-875&volume=12&pages=875-878&publication_year=2006&author=Norton%2CL&author=Massague%2CJ
- https://doi.org/10.1210%2Fendo.138.4.5071's total income per month
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9075737
- Income figures for http://scholar.google.com/scholar_lookup?&title=Reexpression%20of%20the%20type%201%20insulin-like%20growth%20factor%20receptor%20inhibits%20the%20malignant%20phenotype%20of%20simian%20virus%2040%E2%80%89T%20antigen%20immortalized%20human%20prostate%20epithelial%20cells&journal=Endocrinology&doi=10.1210%2Fendo.138.4.5071&volume=138&pages=1728-1735&publication_year=1997&author=Plymate%2CSR&author=Bae%2CVL&author=Maddison%2CL&author=Quinn%2CLS&author=Ware%2CJL
- How much does https://doi.org/10.1002%2Fpros.20099 generate monthly?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15368471
- How much does http://scholar.google.com/scholar_lookup?&title=Androgen%20receptor%20%28AR%29%20expression%20in%20AR-negative%20prostate%20cancer%20cells%20results%20in%20differential%20effects%20of%20DHT%20and%20IGF-I%20on%20proliferation%20and%20AR%20activity%20between%20localized%20and%20metastatic%20tumors&journal=Prostate&doi=10.1002%2Fpros.20099&volume=61&pages=276-290&publication_year=2004&author=Plymate%2CSR&author=Tennant%2CMK&author=Culp%2CSH&author=Woodke%2CL&author=Marcelli%2CM&author=Colman%2CI bring in each month?
- What's the financial intake of https://link.springer.com/doi/10.1007/s11154-007-9037-1?
- What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17447144?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Stromal%20induction%20of%20breast%20cancer%3A%20inflammation%20and%20invasion&journal=Rev%20Endocr%20Metab%20Disord&doi=10.1007%2Fs11154-007-9037-1&volume=8&pages=279-287&publication_year=2007&author=Radisky%2CES&author=Radisky%2CDC?
- How much does https://link.springer.com/doi/10.1007/s10549-006-9392-8 generate monthly?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17004106 is on a monthly basis
- Financial intake of http://scholar.google.com/scholar_lookup?&title=MDA-MB-435%20cells%20are%20derived%20from%20M14%20melanoma%20cells%E2%80%94a%20loss%20for%20breast%20cancer%2C%20but%20a%20boon%20for%20melanoma%20research&journal=Breast%20Cancer%20Res%20Treat&doi=10.1007%2Fs10549-006-9392-8&volume=104&pages=13-19&publication_year=2007&author=Rae%2CJM&author=Creighton%2CCJ&author=Meck%2CJM&author=Haddad%2CBR&author=Johnson%2CMD
- What's https://doi.org/10.1038%2Fsj.onc.1208337's gross income?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15592498 is on a monthly basis
- How much does http://scholar.google.com/scholar_lookup?&title=Caveolin-1%20inhibits%20cell%20detachment-induced%20p53%20activation%20and%20anoikis%20by%20upregulation%20of%20insulin-like%20growth%20factor-I%20receptors%20and%20signaling&journal=Oncogene&doi=10.1038%2Fsj.onc.1208337&volume=24&pages=1338-1347&publication_year=2005&author=Ravid%2CD&author=Maor%2CS&author=Werner%2CH&author=Liscovitch%2CM pull in?
- How much income does https://doi.org/10.1097%2F01.LAB.0000032411.41603.C2 have?
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12379772
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Impact%20of%20insulin-like%20growth%20factor%20receptor-I%20function%20on%20angiogenesis%2C%20growth%2C%20and%20metastasis%20of%20colon%20cancer&journal=Lab%20Invest&doi=10.1097%2F01.LAB.0000032411.41603.C2&volume=82&pages=1377-1389&publication_year=2002&author=Reinmuth%2CN&author=Fan%2CF&author=Liu%2CW&author=Parikh%2CAA&author=Stoeltzing%2CO&author=Jung%2CYD
- What are the total earnings of https://doi.org/10.1158%2F1078-0432.CCR-07-1109?
- What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17875788?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=IMC-A12%2C%20a%20human%20IgG1%20monoclonal%20antibody%20to%20the%20insulin-like%20growth%20factor%20I%20receptor&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-07-1109&volume=13&pages=5549s-5555s&publication_year=2007&author=Rowinsky%2CEK&author=Youssoufian%2CH&author=Tonra%2CJR&author=Solomon%2CP&author=Burtrum%2CD&author=Ludwig%2CDL is on a monthly basis
- https://doi.org/10.1074%2Fjbc.M305403200's revenue stream
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14615489 generate?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=A%20dominant%20negative%20type%20I%20insulin-like%20growth%20factor%20receptor%20inhibits%20metastasis%20of%20human%20cancer%20cells&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M305403200&volume=279&pages=5017-5024&publication_year=2004&author=Sachdev%2CD&author=Hartell%2CJS&author=Lee%2CAV&author=Zhang%2CX&author=Yee%2CD each month?
- Financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12566306
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=A%20chimeric%20humanized%20single-chain%20antibody%20against%20the%20type%20I%20insulin-like%20growth%20factor%20%28IGF%29%20receptor%20renders%20breast%20cancer%20cells%20refractory%20to%20the%20mitogenic%20effects%20of%20IGF-I&journal=Cancer%20Res&volume=63&pages=627-635&publication_year=2003&author=Sachdev%2CD&author=Li%2CSL&author=Hartell%2CJS&author=Fujita-Yamaguchi%2CY&author=Miller%2CJS&author=Yee%2CD?
- How much does https://doi.org/10.1158%2F0008-5472.CAN-05-3126 gross monthly?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16489046's revenue stream
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Down-regulation%20of%20insulin%20receptor%20by%20antibodies%20against%20the%20type%20I%20insulin-like%20growth%20factor%20receptor%3A%20implications%20for%20anti-insulin-like%20growth%20factor%20therapy%20in%20breast%20cancer&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-05-3126&volume=66&pages=2391-2402&publication_year=2006&author=Sachdev%2CD&author=Singh%2CR&author=Fujita-Yamaguchi%2CY&author=Yee%2CD bring in?
- Get to know https://doi.org/10.1158%2F1535-7163.MCT-06-0080's earnings
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17237261?
- How much income is http://scholar.google.com/scholar_lookup?&title=Disrupting%20insulin-like%20growth%20factor%20signaling%20as%20a%20potential%20cancer%20therapy&journal=Mol%20Cancer%20Ther&doi=10.1158%2F1535-7163.MCT-06-0080&volume=6&pages=1-12&publication_year=2007&author=Sachdev%2CD&author=Yee%2CD earning monthly?
- How much does https://doi.org/10.1200%2Fjco.2008.26.15_suppl.3582 pull in monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=A%20phase%20I%20study%20of%20AVE1642%2C%20a%20humanized%20monoclonal%20antibody%20IGF-1R%20%28insulin%20like%20growth%20factor1%20receptor%29%20antagonist%2C%20in%20patients%28pts%29%20with%20advanced%20solid%20tumor%28ST%29&journal=J%20Clin%20Oncology&doi=10.1200%2Fjco.2008.26.15_suppl.3582&volume=26%20%28No%2015S%29&publication_year=2008&author=Tolcher%2CAW&author=Patnaik%2CA&author=Till%2CE&author=Takimoto%2CCH&author=Papadopoulos%2CKP&author=Massard%2CC rake in every month?
- What's the profit of https://doi.org/10.2174%2F1566524033479483?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14601637
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20apoptosis%20in%20tumor%20progression%20and%20metastasis&journal=Curr%20Mol%20Med&doi=10.2174%2F1566524033479483&volume=3&pages=631-642&publication_year=2003&author=Townson%2CJL&author=Naumov%2CGN&author=Chambers%2CAF is on a monthly basis
- How much does https://doi.org/10.1038%2Fbjc.1987.190 gross monthly?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=3663476 bring in?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002206 pull in?
- http://scholar.google.com/scholar_lookup?&title=A%20study%20of%20some%20variables%20in%20a%20tetrazolium%20dye%20%28MTT%29%20based%20assay%20for%20cell%20growth%20and%20chemosensitivity&journal=Br%20J%20Cancer&doi=10.1038%2Fbjc.1987.190&volume=56&pages=279-285&publication_year=1987&author=Twentyman%2CPR&author=Luscombe%2CM's revenue stream
- See how much https://doi.org/10.1038%2Fsj.onc.1202471 makes per month
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10086337?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Anti-apoptotic%20signaling%20of%20the%20IGF-I%20receptor%20in%20fibroblasts%20following%20loss%20of%20matrix%20adhesion&journal=Oncogene&doi=10.1038%2Fsj.onc.1202471&volume=18&pages=1827-1836&publication_year=1999&author=Valentinis%2CB&author=Morrione%2CA&author=Peruzzi%2CF&author=Prisco%2CM&author=Reiss%2CK&author=Baserga%2CR generate?
- How much profit does https://doi.org/10.1158%2F0008-5472.CAN-05-1448 make?
- What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16818629?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Insulin-like%20growth%20factor-I%20receptor%20expression%20regulates%20neuroblastoma%20metastasis%20to%20bone&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-05-1448&volume=66&pages=6570-6578&publication_year=2006&author=van%20Golen%2CCM&author=Schwab%2CTS&author=Kim%2CB&author=Soules%2CME&author=Su%20Oh%2CS&author=Fung%2CK?
- What's the total monthly financial gain of https://doi.org/10.1158%2F1078-0432.CCR-06-0443?
- Get to know http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17062692's earnings
- http://scholar.google.com/scholar_lookup?&title=Combined%20in%20vivo%20effect%20of%20A12%2C%20a%20type%201%20insulin-like%20growth%20factor%20receptor%20antibody%2C%20and%20docetaxel%20against%20prostate%20cancer%20tumors&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-06-0443&volume=12&pages=6153-6160&publication_year=2006&author=Wu%2CJD&author=Haugk%2CK&author=Coleman%2CI&author=Woodke%2CL&author=Vessella%2CR&author=Nelson%2CP's revenue stream
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12907608's revenue stream
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Reduced%20circulating%20insulin-like%20growth%20factor%20I%20levels%20delay%20the%20onset%20of%20chemically%20and%20genetically%20induced%20mammary%20tumors&journal=Cancer%20Res&volume=63&pages=4384-4388&publication_year=2003&author=Wu%2CY&author=Cui%2CK&author=Miyoshi%2CK&author=Hennighausen%2CL&author=Green%2CJE&author=Setser%2CJ?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11861378?
- How much does http://scholar.google.com/scholar_lookup?&title=Circulating%20insulin-like%20growth%20factor-I%20levels%20regulate%20colon%20cancer%20growth%20and%20metastasis&journal=Cancer%20Res&volume=62&pages=1030-1035&publication_year=2002&author=Wu%2CY&author=Yakar%2CS&author=Zhao%2CL&author=Hennighausen%2CL&author=LeRoith%2CD bring in each month?
- How profitable is https://doi.org/10.1073%2Fpnas.96.13.7324?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10377413?
- Income figures for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC22084
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Normal%20growth%20and%20development%20in%20the%20absence%20of%20hepatic%20insulin-like%20growth%20factor%20I&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.96.13.7324&volume=96&pages=7324-7329&publication_year=1999&author=Yakar%2CS&author=Liu%2CJL&author=Stannard%2CB&author=Butler%2CA&author=Accili%2CD&author=Sauer%2CB?
- https://doi.org/10.1359%2Fjbmr.2001.16.8.1486's revenue stream
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11499871 generate?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=A%20bone-seeking%20clone%20exhibits%20different%20biological%20properties%20from%20the%20MDA-MB-231%20parental%20human%20breast%20cancer%20cells%20and%20a%20brain-seeking%20clone%20in%20vivo%20and%20in%20vitro&journal=J%20Bone%20Miner%20Res&doi=10.1359%2Fjbmr.2001.16.8.1486&volume=16&pages=1486-1495&publication_year=2001&author=Yoneda%2CT&author=Williams%2CPJ&author=Hiraga%2CT&author=Niewolna%2CM&author=Nishimura%2CR?
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12154042 make?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Insulin-like%20growth%20factor%20binding%20protein-1%20%28IGFBP-1%29%20inhibits%20breast%20cancer%20cell%20motility&journal=Cancer%20Res&volume=62&pages=4369-4375&publication_year=2002&author=Zhang%2CX&author=Yee%2CD?
- How much does https://citation-needed.springer.com/v2/references/10.1038/onc.2009.316?format=refman&flavour=references earn?
- What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Sachdev?
- Explore the financials of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Sachdev%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=X%20Zhang gross monthly?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22X%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- What's the profit of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=I%20Matise?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22I%20Matise%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=M%20Gaillard-Kelly generate monthly?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22M%20Gaillard-Kelly%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=D%20Yee generate?
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22D%20Yee%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's https://s100.copyright.com/AppDispatchServlet?title=The%20type%20I%20insulin-like%20growth%20factor%20receptor%20regulates%20cancer%20metastasis%20independently%20of%20primary%20tumor%20growth%20by%20promoting%20invasion%20and%20survival&author=D%20Sachdev%20et%20al&contentID=10.1038%2Fonc.2009.316©right=Macmillan%20Publishers%20Limited&publication=0950-9232&publicationDate=2009-10-19&publisherName=SpringerNature&orderBeanReset=true's gross income?
- Income figures for https://citation-needed.springer.com/v2/references/10.1038/onc.2009.316?format=refman&flavour=citation
- Profit of https://doi.org/10.1186/s13045-020-00904-3
- How much money does https://doi.org/10.1007/s10549-020-05629-y generate?
- How much income does https://doi.org/10.1007/s12282-016-0732-1 have?
- What's the financial gain of https://doi.org/10.1186/s12943-015-0482-2?
- How much cash flow does https://doi.org/10.1038/onc.2015.518 have monthly?
- Discover the revenue of https://www.protocols.io/
- What are the earnings of https://www.natureindex.com/?
- What's the monthly money flow for http://www.naturechina.com?
- Discover the revenue of https://www.natureasia.com/ja-jp
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Foundation
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {π¦}
- Crossref