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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC1283098/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC1283098/. The analysis below is for the second page.
Title[redir]:
Genes that mediate breast cancer metastasis to lung - PMC
Description:
By means of in vivo selection, transcriptomic analysis, functional verification and clinical validation, here we identify a set of genes that marks and mediates breast cancer metastasis to the lungs. Some of these genes serve dual functions, ...
Title[redir]:
Genes that mediate breast cancer metastasis to lung - PMC
Description:
By means of in vivo selection, transcriptomic analysis, functional verification and clinical validation, here we identify a set of genes that marks and mediates breast cancer metastasis to the lungs. Some of these genes serve dual functions, ...
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Keywords {🔍}
lung, metastasis, genes, doi, metastatic, cells, breast, cancer, cell, signature, fig, expression, primary, tumour, pubmed, google, scholar, gene, populations, patients, tumours, supplementary, parental, growth, expressed, lines, activity, mice, analysis, survival, bone, nature, mmp, data, selected, lungs, cohort, vivo, aggressive, shown, receptor, mammary, pmc, set, mdamb, metastagenicity, scps, lungmetastatic, vcam, mediate,
Topics {✒️}
dominant-negative helix–loop–helix protein rosetta-type poor-prognosis signature8 10-year lung-metastasis-free survival triple-modality reporter gene rosetta-type poor-prognosis tumour rosetta-type poor-prognosis tumours short-hairpin rna-mediated interference lung-metastasis-free survival restricted helix–loop–helix proteins mammary-fat-pad tumour assays pmc beta search rosetta poor-prognosis signature lung-metastasis-free survival fluorescence-activated cell sorting parental mda-md-231 cells high-glucose dmem medium bone-metastasis-free survival cell line mda-mb-231 melanoma growth-stimulating activity short hairpin construct potent pan-erbb ligand single-cell-derived progenies prostaglandin-endoperoxide synthase ptgs2/cox2 high-dimensional microarray data tissue-wide expression profiling subsequent lung-metastatic generation lung meta-static activity cross-validated multivariate analysis transcriptomic micro-array analysis lung-specific metastatic activity metastasis-specific genes exist organ-specific metastatic subpopulations rosetta microarray platforms aggressive lung-metastatic populations identify poor-prognosis patients lung-metastatic populations selected mda-mb-231 population human breast tumours mda-mb-231 subpopulations identify tumour-specific genes lung metastagenicity signature primary breast cancers rosetta training set primary human carcinomas poor-prognosis tumours mda-mb-231 cells colour scale depicts actin-bundling protein lung metastatic ability mammary fat pad
Questions {❓}
- Metastatic potential: generic predisposition of the primary tumour or rare, metastatic variants-or both?
- SPARC and tumour growth: where the seed meets the soil?
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