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We are analyzing https://www.nature.com/articles/nrn3745.
Title:
Neurobiology of food intake in health and disease | Nature Reviews Neuroscience
Description:
The energy homeostasis system maintains stability of body fat stores over time but can be overridden by activation of feeding neurocircuits during emergent or stressful conditions. In this Review, Schwartz and colleagues highlight crosstalk between homeostatic and emergency feeding circuits in the regulation of energy balance. Under normal conditions, food intake and energy expenditure are balanced by a homeostatic system that maintains stability of body fat content over time. However, this homeostatic system can be overridden by the activation of
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30 years and 10 months (reg. 1994-08-11).
Title:
Neurobiology of food intake in health and disease | Nature Reviews Neuroscience
Description:
The energy homeostasis system maintains stability of body fat stores over time but can be overridden by activation of feeding neurocircuits during emergent or stressful conditions. In this Review, Schwartz and colleagues highlight crosstalk between homeostatic and emergency feeding circuits in the regulation of energy balance. Under normal conditions, food intake and energy expenditure are balanced by a homeostatic system that maintains stability of body fat content over time. However, this homeostatic system can be overridden by the activation of
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Education
- Health & Fitness
- Fitness & Wellness
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π Monumental Traffic: 20M - 50M visitors per month
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google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
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$531,700 per month
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Keywords {π}
pubmed, google, scholar, article, cas, central, leptin, nature, food, energy, neurons, obesity, intake, physiol, hypothalamic, feeding, clin, schwartz, insulin, body, control, weight, diabetes, response, brain, neurosci, rats, receptor, metab, homeostasis, role, invest, agrp, mice, nucleus, cell, balance, melanocortin, system, neuronal, circuits, med, oxytocin, neuron, obese, adiposity, endocrinology, satiety, reward, homeostatic,
Topics {βοΈ}
permissions reprints nature portfolio privacy policy body mass index diabetes research center advertising regional brain response medical research service sandra social media author information authors hypothalamic ikkΞ²/nf-ΞΊb arcuate pro-opiomelanocortin neurons author correspondence palatable high-fat diets insulin activates atp-sensitive physical activity decision-making central leptin infusion atp-sensitive potassium channels fat-rich diet activates cck-induced meal suppression emergency-activated circuits interact personal data serum immunoreactive-leptin concentrations high-fat feeding underlies central hormone resistance body fat content springerlink instant access permissions hypothalamic paraventricular nucleus pro-opiomelanocortin neurons oxytocin-deficient mice data protection fasting-activated hypothalamic neurons long-term orexigenic effects lean-body-mass composition 2-deoxy-d-glucose administration central neural networks obesity-related insulin resistance streptozotocin-induced diabetic rats normal body-weight homeostasis nature genet oxytocin inhibits food nature neurosci express pro-opiomelanocortin nature med nature rev increases food intake early-onset obesity agouti-related protein
Questions {β}
- Adiposity signaling and biological defense against weight gain: absence of protection or central hormone resistance?
- Glucose-sensing neurons: are they physiologically relevant?
- Hypothalamic inflammation: marker or mechanism of obesity pathogenesis?
Schema {πΊοΈ}
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headline:Neurobiology of food intake in health and disease
description:
The energy homeostasis system maintains stability of body fat stores over time but can be overridden by activation of feeding neurocircuits during emergent or stressful conditions. In this Review, Schwartz and colleagues highlight crosstalk between homeostatic and emergency feeding circuits in the regulation of energy balance. Under normal conditions, food intake and energy expenditure are balanced by a homeostatic system that maintains stability of body fat content over time. However, this homeostatic system can be overridden by the activation of 'emergency response circuits' that mediate feeding responses to emergent or stressful stimuli. Inhibition of these circuits is therefore permissive for normal energy homeostasis to occur, and their chronic activation can cause profound, even life-threatening, changes in body fat mass. This Review highlights how the interplay between homeostatic and emergency feeding circuits influences the biologically defended level of body weight under physiological and pathophysiological conditions.
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The energy homeostasis system maintains stability of body fat stores over time but can be overridden by activation of feeding neurocircuits during emergent or stressful conditions. In this Review, Schwartz and colleagues highlight crosstalk between homeostatic and emergency feeding circuits in the regulation of energy balance. Under normal conditions, food intake and energy expenditure are balanced by a homeostatic system that maintains stability of body fat content over time. However, this homeostatic system can be overridden by the activation of 'emergency response circuits' that mediate feeding responses to emergent or stressful stimuli. Inhibition of these circuits is therefore permissive for normal energy homeostasis to occur, and their chronic activation can cause profound, even life-threatening, changes in body fat mass. This Review highlights how the interplay between homeostatic and emergency feeding circuits influences the biologically defended level of body weight under physiological and pathophysiological conditions.
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