
NATURE . COM {
}
Title:
Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy | Nature Reviews Cancer
Description:
Clinical trial results with matrix metalloproteinase (MMP) inhibitors have been poor. So, which MMPs are validated drug targets with a crucial role in disease pathogenesis and which MMPs are actually proteins that have unacceptable deleterious effects when inhibited (anti-targets)? The matrix metalloproteinases (MMPs) mediate homeostasis of the extracellular environment. They have multiple signalling activities that are commonly altered during tumorigenesis and that might serve as intervention points for anticancer drugs. However, there are many criteria to consider in validating MMPs as drug targets and for the development of MMP inhibitors. The inhibition of some MMPs could have pro-tumorigenic effects (making them anti-targets), counterbalancing the benefits of target inhibition. These effects might partially account for the failure of MMP inhibitors in clinical trials. What are the major challenges in MMP target validation and MMP-inhibitor-drug development?
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {📚}
- Education
- Health & Fitness
- Science
Content Management System {📝}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of nature.com audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {💸}
Display Ads {🎯}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {💰}
Display Ads {🎯}
$63,100 per month
Our estimates place Nature.com's monthly online earnings from display ads at $42,042 to $115,616.
Keywords {🔍}
google, scholar, pubmed, cas, cancer, nature, matrix, metalloproteinase, breast, cell, inhibitors, biol, central, res, metalloproteinases, mmp, rev, human, chem, expression, access, cells, mice, article, drug, metastasis, research, therapy, tumor, med, british, columbia, content, target, collagen, matrisian, cookies, development, inhibition, science, protease, progression, privacy, targets, christopher, mmps, clinical, validation, open, discovery,
Topics {✒️}
permissions reprints nature portfolio privacy policy advertising mcp-1-tnfα cross-regulatory pathway cancer cell–adipocyte interaction/crosstalk discovery tools isotope-coded affinity tags author information authors double-blind placebo-controlled antisense rna-induced reduction blood research mmp-inhibitor-drug development biomedical research modify n-timp2 specificity isotope dilution-mass spectrometry author correspondence monocyte chemoattractant protein-3 nature cell biol national cancer institute social media ebsco media breast cancer development blood–brain barrier disruption cxcl12–cxcr4 chemotactic pathway leukolysin/mt6-mmp/mmp-25 gelatinase a-deficient mice personal data reciprocal tumor–microenvironment interactions mechanism-based gelatinase inhibitor springerlink instant access data protection permissions nature rev mass spectrometry-based proteomics nature neurosci structure-based drug design nature genet nature biotechnol nature med growth factor res canadian cancer association diet-induced obesity distinct collagen binding metalloproteinase substrate specificity metastatic potential correlates ben-baruch nature 284 nature 436 nature 390
Questions {❓}
- What are the major challenges in MMP target validation and MMP-inhibitor-drug development?
Schema {🗺️}
WebPage:
mainEntity:
headline:Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
description:Clinical trial results with matrix metalloproteinase (MMP) inhibitors have been poor. So, which MMPs are validated drug targets with a crucial role in disease pathogenesis and which MMPs are actually proteins that have unacceptable deleterious effects when inhibited (anti-targets)? The matrix metalloproteinases (MMPs) mediate homeostasis of the extracellular environment. They have multiple signalling activities that are commonly altered during tumorigenesis and that might serve as intervention points for anticancer drugs. However, there are many criteria to consider in validating MMPs as drug targets and for the development of MMP inhibitors. The inhibition of some MMPs could have pro-tumorigenic effects (making them anti-targets), counterbalancing the benefits of target inhibition. These effects might partially account for the failure of MMP inhibitors in clinical trials. What are the major challenges in MMP target validation and MMP-inhibitor-drug development?
datePublished:
dateModified:
pageStart:227
pageEnd:239
sameAs:https://doi.org/10.1038/nrc1821
keywords:
Biomedicine
general
Cancer Research
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Figa_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Figb_HTML.jpg
isPartOf:
name:Nature Reviews Cancer
issn:
1474-1768
1474-175X
volumeNumber:6
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Christopher M. Overall
affiliation:
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
type:Organization
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute
address:
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute, Vancouver, Canada
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Oded Kleifeld
affiliation:
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis, Departments of Oral Biological & Medical Sciences, and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
description:Clinical trial results with matrix metalloproteinase (MMP) inhibitors have been poor. So, which MMPs are validated drug targets with a crucial role in disease pathogenesis and which MMPs are actually proteins that have unacceptable deleterious effects when inhibited (anti-targets)? The matrix metalloproteinases (MMPs) mediate homeostasis of the extracellular environment. They have multiple signalling activities that are commonly altered during tumorigenesis and that might serve as intervention points for anticancer drugs. However, there are many criteria to consider in validating MMPs as drug targets and for the development of MMP inhibitors. The inhibition of some MMPs could have pro-tumorigenic effects (making them anti-targets), counterbalancing the benefits of target inhibition. These effects might partially account for the failure of MMP inhibitors in clinical trials. What are the major challenges in MMP target validation and MMP-inhibitor-drug development?
datePublished:
dateModified:
pageStart:227
pageEnd:239
sameAs:https://doi.org/10.1038/nrc1821
keywords:
Biomedicine
general
Cancer Research
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Figa_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fnrc1821/MediaObjects/41568_2006_Article_BFnrc1821_Figb_HTML.jpg
isPartOf:
name:Nature Reviews Cancer
issn:
1474-1768
1474-175X
volumeNumber:6
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Christopher M. Overall
affiliation:
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
type:Organization
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute
address:
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute, Vancouver, Canada
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:Oded Kleifeld
affiliation:
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis, Departments of Oral Biological & Medical Sciences, and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Nature Reviews Cancer
issn:
1474-1768
1474-175X
volumeNumber:6
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute
address:
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute, Vancouver, Canada
type:PostalAddress
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis, Departments of Oral Biological & Medical Sciences, and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Christopher M. Overall
affiliation:
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
type:Organization
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute
address:
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute, Vancouver, Canada
type:PostalAddress
type:Organization
email:[email protected]
name:Oded Kleifeld
affiliation:
name:University of British Columbia
address:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis, Departments of Oral Biological & Medical Sciences, and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
type:PostalAddress
type:Organization
PostalAddress:
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
name:the University of British Columbia Centre for Blood Research, 4.401 Life Sciences Institute, Vancouver, Canada
name:the University of British Columbia Centre for Blood Research, CBCRA Program in Breast Cancer Metastasis, Departments of Oral Biological & Medical Sciences, and Biochemistry & Molecular Biology, University of British Columbia, Vancouver, Canada
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {🔗}(235)
- How much does https://link.springer.com/article/10.1038/nrc1821?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle gross monthly?
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10720314
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Drug%20discovery%3A%20a%20historical%20perspective&journal=Science&volume=287&pages=1960-1964&publication_year=2000&author=Drews%2CJ?
- How much income does http://scholar.google.com/scholar_lookup?&title=Target%20discovery&journal=Nature%20Rev.%20Drug%20Discov.&volume=2&pages=831-838&publication_year=2003&author=Lindsay%2CMA have?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14559105?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Target%20validation&journal=Curr.%20Opin.%20Pharmacol.&volume=3&pages=571-577&publication_year=2003&author=Williams%2CM?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Protease%20degradomics%3A%20a%20new%20challenge%20for%20proteomics&journal=Nature%20Rev.%20Mol.%20Cell%20Biol.&volume=3&pages=509-519&publication_year=2002&author=L%C3%B3pez-Ot%C3%ADn%2CC&author=Overall%2CCM is on a monthly basis
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12838346 make?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Human%20and%20mouse%20proteases%3A%20a%20comparative%20genomic%20approach&journal=Nature%20Rev.%20Genet.&volume=4&pages=544-558&publication_year=2003&author=Puente%2CXS&author=Sanchez%2CLM&author=Overall%2CCM&author=L%C3%B3pez-Ot%C3%ADn%2CC
- Profit of http://scholar.google.com/scholar_lookup?&title=Target%20identification%20and%20validation%20in%20drug%20discovery%3A%20the%20role%20of%20proteomics&journal=Biochem.%20Pharmacol.&volume=69&pages=1133-1139&publication_year=2005&author=Koopec%2CKK&author=Bozyczko-Coyne%2CD&author=Williams%2CM
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=6243750 making per month?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Metastatic%20potential%20correlates%20with%20enzymatic%20degradation%20of%20basement%20membrane%20collagen&journal=Nature&volume=284&pages=67-68&publication_year=1980&author=Liotta%2CLA?
- What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7657518?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Progelatinase%20A%20activation%20during%20tumor%20cell%20invasion&journal=Invasion%20Metastasis&volume=14&pages=259-268&publication_year=1994&author=Stetler-Stevenson%2CWG earns monthly
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10419448?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinases&journal=J.%20Biol.%20Chem.&volume=274&pages=21491-21494&publication_year=1999&author=Nagase%2CH&author=Woessner%2CJF?
- How much money does http://scholar.google.com/scholar_lookup?&title=New%20functions%20for%20the%20matrix%20metalloproteinases%20in%20cancer%20progression&journal=Nature%20Rev.%20Cancer&volume=2&pages=161-174&publication_year=2002&author=Egeblad%2CM&author=Werb%2CZ make?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16049480?
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283098?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Genes%20that%20mediate%20breast%20cancer%20metastasis%20to%20lung&journal=Nature&volume=436&pages=518-524&publication_year=2005&author=Minn%2CAJ is on a monthly basis
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15630443 is on a monthly basis
- Explore the financials of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539194
- How much income is http://scholar.google.com/scholar_lookup?&title=Distinct%20organ-specific%20metastatic%20potential%20of%20individual%20breast%20cancer%20cells%20and%20primary%20tumors&journal=J.%20Clin.%20Invest.&volume=115&pages=44-55&publication_year=2005&author=Minn%2CAJ earning monthly?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16001073?
- What is the monthly revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784913?
- How much does http://scholar.google.com/scholar_lookup?&title=Rac1b%20and%20reactive%20oxygen%20species%20mediate%20MMP-3-induced%20EMT%20and%20genomic%20instability&journal=Nature&volume=436&pages=123-127&publication_year=2005&author=Radisky%2CDC pull in?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Breast%20cancer%20metastasis%3A%20markers%20and%20models&journal=Nature%20Rev.%20Cancer&volume=5&pages=591-602&publication_year=2005&author=Weigelt%2CB&author=Peterse%2CJL&author=van%27t%20Veer%2CLJ is on a monthly basis
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11426650 each month?
- http://scholar.google.com/scholar_lookup?&title=Critical%20appraisal%20of%20the%20use%20of%20matrix%20metalloproteinase%20inhibitors%20in%20cancer%20treatment&journal=Oncogene&volume=19&pages=6642-6650&publication_year=2000&author=Zucker%2CS&author=Cao%2CJ&author=Chen%2CWT's total income per month
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Strategies%20for%20MMP%20inhibition%20in%20cancer%3A%20innovations%20for%20the%20post-trial%20era&journal=Nature%20Rev.%20Cancer&volume=2&pages=657-672&publication_year=2002&author=Overall%2CCM&author=L%C3%B3pez-Ot%C3%ADn%2CC produce monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11923519 net monthly?
- How much money does http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase%20inhibitors%20and%20cancer%3A%20trials%20and%20tribulations&journal=Science&volume=295&pages=2387-2392&publication_year=2002&author=Coussens%2CLM&author=Fingleton%2CB&author=Matrisian%2CLM generate?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12783574 bring in?
- http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase%20inhibitors%20for%20cancer%20therapy%3A%20the%20current%20situation%20and%20future%20prospects&journal=Expert%20Opin.%20Ther.%20Targets&volume=7&pages=385-397&publication_year=2003&author=Fingleton%2CB's total income per month
- See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10201949 makes per month
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20matrix%20metalloproteinases%20prevents%20allergen-induced%20airway%20inflammation%20in%20a%20murine%20model%20of%20asthma&journal=J.%20Immunol.&volume=162&pages=4212-4219&publication_year=1999&author=Kumagai%2CK?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11544020 make?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinases%3A%20they%27re%20not%20just%20for%20matrix%20anymore%21&journal=Curr.%20Opin.%20Cell%20Biol.&volume=13&pages=534-540&publication_year=2001&author=McCawley%2CLJ&author=Matrisian%2CLM
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12411666's gross income?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Blood%E2%80%93brain%20barrier%20disruption%20and%20matrix%20metalloproteinase-9%20expression%20during%20reperfusion%20injury%3A%20mechanical%20versus%20embolic%20focal%20ischemia%20in%20spontaneously%20hypertensive%20rats&journal=Stroke&volume=33&pages=2711-2717&publication_year=2002&author=Aoki%2CT&author=Sumii%2CT&author=Mori%2CT&author=Wang%2CX&author=Lo%2CEH
- What's the financial outcome of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15508185?
- Income figures for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133754
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Dilating%20the%20degradome%3A%20matrix%20metalloproteinase-2%20cuts%20to%20the%20heart%20of%20the%20matter&journal=Biochem.%20J.&volume=383&pages=E5-E7&publication_year=2004&author=Overall%2CCM
- Income figures for http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinases%20as%20modulators%20of%20inflammation%20and%20innate%20immunity&journal=Nature%20Rev.%20Immunol&volume=4&pages=617-629&publication_year=2004&author=Parks%2CWC&author=Wilson%2CCL&author=L%C3%B3pez-Boado%2CYS
- What's the revenue for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10221914?
- Get to know http://scholar.google.com/scholar_lookup?&title=Effects%20of%20angiogenesis%20inhibitors%20on%20multistage%20carcinogenesis%20in%20mice&journal=Science&volume=284&pages=808-812&publication_year=1999&author=Bergers%2CG&author=Javaherian%2CK&author=Lo%2CKM&author=Folkman%2CJ&author=Hanahan%2CD's earnings
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Antiangiogenic%20therapy%20of%20experimental%20cancer%20does%20not%20induce%20acquired%20drug%20resistance&journal=Nature&volume=390&pages=404-407&publication_year=1997&author=Boehm%2CT&author=Folkman%2CJ&author=Browder%2CT&author=O%27Reilly%2CMS
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11571304?
- Get to know http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase%20activity%20inactivates%20the%20chemokine%20stromal-cell%20derived%20factor-1&journal=J.%20Biol.%20Chem.&volume=276&pages=43503-43508&publication_year=2001&author=McQuibban%2CGA's earnings
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12149192 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase%20processing%20of%20monocyte%20chemoattractant%20proteins%20generates%20CC%20chemokine%20receptor%20antagonists%20with%20anti-inflammatory%20properties%20in%20vivo&journal=Blood&volume=100&pages=1160-1167&publication_year=2002&author=McQuibban%2CGA earn?
- Profit of http://scholar.google.com/scholar_lookup?&title=The%20CXCL12%E2%80%93CXCR4%20chemotactic%20pathway%20as%20a%20target%20of%20adjuvant%20breast%20cancer%20therapies&journal=Nature%20Rev.%20Cancer&volume=4&pages=901-909&publication_year=2004&author=Epstein%2CRJ
- How much money does http://scholar.google.com/scholar_lookup?&title=Cancer%20and%20the%20chemokine%20network&journal=Nature%20Rev.%20Cancer&volume=4&pages=540-550&publication_year=2004&author=Balkwill%2CF generate?
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12826635
- How much money does http://scholar.google.com/scholar_lookup?&title=A%20phase%202%20study%20of%20bortezomib%20in%20relapsed%2C%20refractory%20myeloma&journal=N.%20Engl.%20J.%20Med.&volume=348&pages=2609-2617&publication_year=2003&author=Richardson%2CPG make?
- Income figures for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12353914
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Molecular%20determinants%20of%20metalloproteinase%20substrate%20specificity%3A%20matrix%20metalloproteinase%20substrate%20binding%20domains%2C%20modules%2C%20and%20exosites&journal=Mol.%20Biotechnol.&volume=22&pages=51-86&publication_year=2002&author=Overall%2CCM?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15470193?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Failing%20the%20public%20health%20%E2%80%94%20Rofecoxib%2C%20Merck%2C%20and%20the%20FDA&journal=N.%20Engl.%20J.%20Med.&volume=351&pages=1707-1709&publication_year=2004&author=Topol%2CEJ?
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15713946 making per month?
- http://scholar.google.com/scholar_lookup?&title=COX-2%20inhibitors%20%E2%80%94%20lessons%20in%20drug%20safety&journal=N.%20Engl.%20J.%20Med.&volume=352&pages=1133-1135&publication_year=2005&author=Psaty%2CBM&author=Furburg%2CCD's revenue stream
- http://scholar.google.com/scholar_lookup?&title=Merck%20faces%20ongoing%20claims%20after%20Texan%20ruling%20on%20Rofecoxib&journal=Br.%20Med.%20J.&volume=331&publication_year=2005&author=Tanne%2CJH's financial summary
- How much money does http://scholar.google.com/scholar_lookup?&title=The%20pathogenesis%20of%20cancer%20metastasis%3A%20the%20%27seed%20and%20soil%27%20hypothesis%20revisited&journal=Nature%20Rev.%20Cancer&volume=3&pages=453-458&publication_year=2003&author=Fidler%2CIJ make?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12668656 earn?
- Monthly income for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172772
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=uPARAP%2FEndo180%20is%20essential%20for%20cellular%20uptake%20of%20collagen%20and%20promotes%20fibroblast%20collagen%20adhesion&journal=J.%20Cell%20Biol.&volume=160&pages=1009-1015&publication_year=2003&author=Engelholm%2CLH?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15967816 gross monthly?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171632?
- http://scholar.google.com/scholar_lookup?&title=Intracellular%20collagen%20degradation%20mediated%20by%20uPARAP%2FEndo180%20is%20a%20major%20pathway%20of%20extracellular%20matrix%20turnover%20during%20malignancy&journal=J.%20Cell%20Biol.&volume=169&pages=977-985&publication_year=2005&author=Curino%2CAC income
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12837607
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Tales%20from%20the%20crypt%5Bic%5D%20sites%20of%20the%20extracellular%20matrix&journal=Trends%20Cell%20Biol.&volume=13&pages=366-375&publication_year=2003&author=Schenk%2CS&author=Quaranta%2CV
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12684035
- Get to know http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinases%20process%20the%20laminin-5%20%CE%B32-chain%20and%20regulate%20epithelial%20cell%20migration&journal=Biochem.%20Biophys.%20Res.%20Commun.&volume=303&pages=1012-1017&publication_year=2003&author=Pirila%2CE's earnings
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15729716
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Metalloproteinases%20and%20their%20inhibitors%20in%20tumor%20angiogenesis&journal=Int.%20J.%20Cancer&volume=115&pages=849-860&publication_year=2005&author=Handsley%2CMM&author=Edwards%2CDR bring in?
- How much money does http://scholar.google.com/scholar_lookup?&title=Angiostatin%20induces%20and%20sustains%20dormancy%20of%20human%20primary%20tumors%20in%20mice&journal=Nature%20Med.&volume=2&pages=689-692&publication_year=1996&author=O%27Reilly%2CMS&author=Holmgren%2CL&author=Chen%2CC&author=Folkman%2CJ make?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15118097 pull in monthly?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Membrane%20protease%20proteomics%3A%20isotope-coded%20affinity%20tag%20MS%20identification%20of%20undescribed%20MT1-matrix%20metalloproteinase%20substrates&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&volume=101&pages=6917-6922&publication_year=2004&author=Tam%2CEM&author=Morrison%2CCJ&author=Wu%2CYI&author=Stack%2CMS&author=Overall%2CCM
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11774028 produce monthly?
- Learn how profitable http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1506562 is on a monthly basis
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Matrilysin%20%28MMP-7%29%20expression%20selects%20for%20cells%20with%20reduced%20sensitivity%20to%20apoptosis&journal=Neoplasia&volume=3&pages=459-468&publication_year=2001&author=Fingleton%2CB&author=Vargo-Gogola%2CT&author=Crawford%2CHC&author=Matrisian%2CLM?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14517555?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Loss%20of%20collagenase-2%20confers%20increased%20skin%20tumor%20susceptibility%20to%20male%20mice&journal=Nature%20Genet.&volume=35&pages=252-257&publication_year=2003&author=Balbin%2CM
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10947989 net monthly?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Inflammation%20dampened%20by%20gelatinase%20A%20cleavage%20of%20monocyte%20chemoattractant%20protein-3&journal=Science&volume=289&pages=1202-1206&publication_year=2000&author=McQuibban%2CGA?
- What's the revenue for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8817668?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinases%20as%20insulin-like%20growth%20factor%20binding%20protein-degrading%20proteinases&journal=Prog.%20Growth%20Factor%20Res.&volume=6&pages=255-263&publication_year=1995&author=Fowlkes%2CJL&author=Thrailkill%2CKM&author=Serra%2CDM&author=Suzuki%2CK&author=Nagase%2CH?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16103088 bring in each month?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Insulin-like%20growth%20factor%20binding%20protein-5%20is%20a%20target%20of%20matrix%20metalloproteinase-7%3A%20implications%20for%20epithelial-mesenchymal%20signaling&journal=Cancer%20Res.&volume=65&pages=7363-7369&publication_year=2005&author=Hemers%2CE?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15576013
- How much profit is http://scholar.google.com/scholar_lookup?&title=COX-2%20selective%20inhibitors%20cardiac%20toxicity%3A%20getting%20to%20the%20heart%20of%20the%20matter&journal=J.%20Pharm.%20Pharm.%20Sci.&volume=7&pages=332-336&publication_year=2004&author=Davies%2CNM&author=Jamali%2CF making per month?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2465572
- How profitable is http://scholar.google.com/scholar_lookup?&title=Antisense%20RNA-induced%20reduction%20in%20murine%20TIMP%20levels%20confers%20oncogenicity%20on%20Swiss%203T3%20cells&journal=Science&volume=243&pages=947-950&publication_year=1989&author=Khokha%2CR?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8756718?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Patterns%20and%20emerging%20mechanisms%20of%20the%20angiogenic%20switch%20during%20tumorigenesis&journal=Cell&volume=86&pages=353-364&publication_year=1996&author=Hanahan%2CD&author=Folkman%2CJ?
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7515971
- Financial intake of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC236359
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Progressive%20squamous%20epithelial%20neoplasia%20in%20K14-human%20papillomavirus%20type%2016%20transgenic%20mice&journal=J.%20Virol.&volume=68&pages=4358-4368&publication_year=1994&author=Arbeit%2CJM&author=Munger%2CK&author=Howley%2CPM&author=Hanahan%2CD
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12490959 earn?
- Learn how profitable http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803035 is on a monthly basis
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Inflammation%20and%20cancer&journal=Nature&volume=420&pages=860-867&publication_year=2002&author=Coussens%2CLM&author=Werb%2CZ generate?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12559043 bring in each month?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Host%20microenvironment%20in%20breast%20cancer%20development%3A%20inflammatory%20cells%2C%20cytokines%20and%20chemokines%20in%20breast%20cancer%20progression%3A%20reciprocal%20tumor%E2%80%93microenvironment%20interactions&journal=Breast%20Cancer%20Res.&volume=5&pages=31-36&publication_year=2003&author=Ben-Baruch%2CA
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16139507 make?
- See how much http://scholar.google.com/scholar_lookup?&title=Inflammation-associated%20immune%20suppression%20in%20cancer%3A%20the%20roles%20played%20by%20cytokines%2C%20chemokines%20and%20additional%20mediators&journal=Semin.%20Cancer%20Biol.&volume=16&pages=38-52&publication_year=2006&author=Ben-Baruch%2CA makes per month
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11910072's total income per month
- What's the income of http://scholar.google.com/scholar_lookup?&title=A%20system%20for%20stable%20expression%20of%20short%20interfering%20RNAs%20in%20mammalian%20cell&journal=Science&volume=296&pages=550-553&publication_year=2002&author=Brummelkamp%2CTR&author=Bernards%2CR&author=Agami%2CR?
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12085177 make?
- What is the earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375430?
- How much does http://scholar.google.com/scholar_lookup?&title=Marimastat%20as%20maintenance%20therapy%20for%20patients%20with%20advanced%20gastric%20cancer%3A%20a%20randomised%20trial&journal=Br.%20J.%20Cancer&volume=86&pages=1864-1870&publication_year=2002&author=Bramhall%2CSR gross monthly?
- See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12107836 makes per month
- What's the financial gain of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376102?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=A%20double-blind%20placebo-controlled%2C%20randomised%20study%20comparing%20gemcitabine%20and%20marimastat%20with%20gemcitabine%20and%20placebo%20as%20first%20line%20therapy%20in%20patients%20with%20advanced%20pancreatic%20cancer&journal=Br.%20J.%20Cancer&volume=87&pages=161-167&publication_year=2002&author=Bramhall%2CSR?
- How much income is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11870183 earning monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Phase%20II%20trial%20of%20temozolomide%20plus%20the%20matrix%20metalloproteinase%20inhibitor%2C%20marimastat%2C%20in%20recurrent%20and%20progressive%20glioblastoma%20multiforme&journal=J.%20Clin.%20Oncol.&volume=20&pages=1383-1388&publication_year=2002&author=Groves%2CMD make?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12680160 income
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Randomised%20double%20blind%20placebo%20control%20study%20of%20adjuvant%20treatment%20with%20the%20metalloproteinase%20inhibitor%2C%20Marimastat%20in%20patients%20with%20inoperable%20colorectal%20hepatic%20metastases%3A%20significant%20survival%20advantage%20in%20patients%20with%20musculoskeletal%20side-effects&journal=Anticancer%20Res.&volume=23&pages=639-645&publication_year=2003&author=King%2CJ&author=Zhao%2CJ&author=Clingan%2CP&author=Morris%2CD each month?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Gene%20expression%20profiling%20predicts%20clinical%20outcome%20of%20breast%20cancer&journal=Nature&volume=415&pages=530-536&publication_year=2002&author=van%27t%20Veer%2CLJ
- How much income is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8597958 earning monthly?
- http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase-1%20is%20associated%20with%20poor%20prognosis%20in%20colorectal%20cancer&journal=Nature%20Med.&volume=2&pages=461-462&publication_year=1996&author=Murray%2CGI&author=Duncan%2CME&author=O%27Neil%2CP&author=Melvin%2CWT&author=Fothergill%2CJE's revenue stream
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9500469 generate monthly?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Reduced%20angiogenesis%20and%20tumor%20progression%20in%20gelatinase%20A-deficient%20mice&journal=Cancer%20Res.&volume=58&pages=1048-1051&publication_year=1998&author=Itoh%2CT?
- How much income is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15867341 earning monthly?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Antimetastatic%20activity%20of%20a%20novel%20mechanism-based%20gelatinase%20inhibitor&journal=Cancer%20Res.&volume=65&pages=3523-356&publication_year=2005&author=Kruger%2CA
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14744781
- http://scholar.google.com/scholar_lookup?&title=Pro-matrix%20metalloproteinase-2%20transfection%20increases%20orthotopic%20primary%20growth%20and%20experimental%20metastasis%20of%20MDA-MB-231%20human%20breast%20cancer%20cells%20in%20nude%20mice&journal=Cancer%20Res.&volume=64&pages=652-658&publication_year=2004&author=Tester%2CAM's financial summary
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11025665's total income per month
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase-9%20triggers%20the%20angiogenic%20switch%20during%20carcinogenesis&journal=Nature%20Cell%20Biol.&volume=2&pages=737-744&publication_year=2000&author=Bergers%2CG?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15534110
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Altered%20expression%20of%20metastasis-associated%20and%20regulatory%20molecules%20in%20effusions%20from%20breast%20cancer%20patients%3A%20a%20novel%20model%20for%20tumor%20progression&journal=Clin.%20Cancer%20Res.&volume=10&pages=7335-7346&publication_year=2004&author=Davidson%2CB generate?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9037065's revenue stream
- http://scholar.google.com/scholar_lookup?&title=Intestinal%20tumorigenesis%20is%20suppressed%20in%20mice%20lacking%20the%20metalloproteinase%20matrilysin&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&volume=94&pages=1402-1407&publication_year=1997&author=Wilson%2CCL&author=Heppner%2CKJ&author=Labosky%2CPA&author=Hogan%2CBL&author=Matrisian%2CLM's revenue stream
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12045257 bring in?
- How much revenue does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150998 bring in?
- How much income does http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase-7%20is%20expressed%20by%20pancreatic%20cancer%20precursors%20and%20regulates%20acinar-to-ductal%20metaplasia%20in%20exocrine%20pancrease&journal=J.%20Clin.%20Invest.&volume=109&pages=1437-1344&publication_year=2002&author=Crawford%2CHC&author=Scoggins%2CCR&author=Washington%2CMK&author=Matrisian%2CLM have?
- What's the monthly money flow for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12778076?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741031
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Cooperative%20effects%20of%20matrix%20metalloproteinase%20and%20cyclooxygenase-2%20inhibition%20on%20intestinal%20adenoma%20reduction&journal=Br.%20J.%20Cancer&volume=88&pages=1445-1452&publication_year=2003&author=Wagenaar-Miller%2CRA
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14996728 make?
- How much money does http://scholar.google.com/scholar_lookup?&title=Altered%20metastatic%20behavior%20of%20human%20breast%20cancer%20cells%20after%20experimental%20manipulation%20of%20matrix%20metalloproteinase%208%20gene%20expression&journal=Cancer%20Res.&volume=64&pages=1687-1694&publication_year=2004&author=Montel%2CV make?
- How much income is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11081634 earning monthly?
- Find out how much http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843102 earns monthly
- How much revenue does http://scholar.google.com/scholar_lookup?&title=MMP-9%20supplied%20by%20bone%20marrow-derived%20cells%20contributes%20to%20skin%20carcinogenesis&journal=Cell&volume=103&pages=481-490&publication_year=2000&author=Coussens%2CLM&author=Tinkle%2CCL&author=Hanahan%2CD&author=Werb%2CZ generate?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7882342's revenue stream
- How much does http://scholar.google.com/scholar_lookup?&title=Decreased%20tumor%20formation%20in%207%2C12-dimethylbenzanthracene-treated%20stromelysin-1%20transgenic%20mice%20is%20associated%20with%20alterations%20in%20mammary%20epithelial%20cell%20apoptosis&journal=Cancer%20Res.&volume=55&pages=1401-1406&publication_year=1995&author=Witty%2CJP&author=Lempka%2CT&author=Coffey%2CRJ&author=Matrisian%2CLM net monthly?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15466188?
- http://scholar.google.com/scholar_lookup?&title=A%20protective%20role%20for%20matrix%20metalloproteinase-3%20in%20squamous%20cell%20carcinoma&journal=Cancer%20Res.&volume=64&pages=6965-6972&publication_year=2004&author=McCawley%2CLJ&author=Crawford%2CHC&author=King%2CLE&author=Mudgett%2CJ&author=Matrisian%2CLM income
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9755235 pull in monthly?
- http://scholar.google.com/scholar_lookup?&title=Expression%20of%20human%20macrophage%20metalloelastase%20gene%20in%20hepatocellular%20carcinoma%3A%20correlation%20with%20angiostatin%20generation%20and%20its%20clinical%20significance&journal=Hepatology&volume=28&pages=986-993&publication_year=1998&author=Gorrin%20Rivas%2CMJ's revenue stream
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11283927
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Human%20macrophage%20metalloelastase%20gene%20expression%20in%20colorectal%20carcinoma%20and%20its%20clinicopathologic%20significance&journal=Cancer&volume=91&pages=1277-1283&publication_year=2001&author=Yang%2CW?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2174435's financial summary
- How profitable is http://scholar.google.com/scholar_lookup?&title=Concanavalin%20A%20produces%20a%20matrix-degradative%20phenotype%20in%20human%20fibroblasts.%20Induction%20and%20endogenous%20activation%20of%20collagenase%2C%2072-kDa%20gelatinase%2C%20and%20Pump-1%20is%20accompanied%20by%20the%20suppression%20of%20the%20tissue%20inhibitor%20of%20matrix%20metalloproteinases&journal=J.%20Biol.%20Chem.&volume=265&pages=21141-21151&publication_year=1990&author=Overall%2CCM&author=Sodek%2CJ?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10520996
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=MT1-MMP-deficient%20mice%20develop%20dwarfism%2C%20osteopenia%2C%20arthritis%2C%20and%20connective%20tissue%20disease%20due%20to%20inadequate%20collagen%20turnover&journal=Cell&volume=99&pages=81-92&publication_year=1999&author=Holmbeck%2CK?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15292230's gross income?
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Characterization%20of%20the%20distinct%20collagen%20binding%2C%20helicase%20and%20cleavage%20mechanisms%20of%20matrix%20metalloproteinase%202%20and%2014%20%28gelatinase%20A%20and%20MT1-MMP%29%3A%20the%20differential%20roles%20of%20the%20MMP%20hemopexin%20C%20domains%20and%20the%20MMP-2%20fibronectin%20type%20II%20modules%20in%20collagen%20triple%20helicase%20activities&journal=J.%20Biol.%20Chem.&volume=279&pages=43336-4344&publication_year=2004&author=Tam%2CEM&author=Moore%2CTR&author=Butler%2CGS&author=Overall%2CCM?
- What's the income generated by http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15255181 each month?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Protease%20degradomics%3A%20mass%20spectrometry%20discovery%20of%20protease%20substrates%20and%20the%20CLIP-CHIP%2C%20a%20dedicated%20DNA%20microarray%20of%20all%20human%20proteases%20and%20inhibitors&journal=Biol.%20Chem.&volume=385&pages=493-504&publication_year=2004&author=Overall%2CCM produce monthly?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12842083
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=A%20multigenic%20program%20mediating%20breast%20cancer%20metastasis%20to%20bone&journal=Cancer%20Cell&volume=3&pages=537-549&publication_year=2003&author=Kang%2CY?
- How much does http://scholar.google.com/scholar_lookup?&title=Involvement%20of%20chemokine%20receptors%20in%20breast%20cancer%20metastasis&journal=Nature&volume=410&pages=50-56&publication_year=2001&author=Muller%2CA gross monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15081541 pull in?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=The%20tumor%20microenvironment%3A%20CXCR4%20is%20associated%20with%20distinct%20protein%20expression%20patterns%20in%20neuroblastoma%20cells&journal=Immunol.%20Lett.&volume=92&pages=163-169&publication_year=2004&author=Nevo%2CI?
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14502291
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Metalloproteinase%20cleavage%20of%20the%20chemokine%20SDF-1%CE%B1%20induces%20neuronal%20apoptosis%20in%20HIV%20encephalitis&journal=Nature%20Neurosci.&volume=6&pages=1064-1071&publication_year=2003&author=Zhang%2CK?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12918065 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Progression%20of%20mouse%20mammary%20tumors%3A%20MCP-1-TNF%CE%B1%20cross-regulatory%20pathway%20and%20clonal%20expression%20of%20promalignancy%20and%20antimalignancy%20factors&journal=Int.%20J.%20Cancer&volume=106&pages=879-886&publication_year=2003&author=Neumark%2CE&author=Sagi-Assif%2CO&author=Shalmon%2CB&author=Ben-Baruch%2CA&author=Witz%2CIP rake in every month?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1701851 make?
- How much income does http://scholar.google.com/scholar_lookup?&title=A%20novel%20metalloproteinase%20gene%20specifically%20expressed%20in%20stromal%20cells%20of%20breast%20carcinomas&journal=Nature&volume=348&pages=699-704&publication_year=1990&author=Basset%2CP have?
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11280785
- How much does http://scholar.google.com/scholar_lookup?&title=High%20cancer%20cell%20death%20in%20syngeneic%20tumors%20developed%20in%20host%20mice%20deficient%20for%20the%20stromelysin-3%20matrix%20metalloproteinase&journal=Cancer%20Res.&volume=61&pages=2189-2193&publication_year=2001&author=Boulay%2CA net monthly?
- Financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16322233
- How profitable is http://scholar.google.com/scholar_lookup?&title=Stromelysin-3%20is%20a%20potent%20negative%20regulator%20of%20adipogenesis%20participating%20to%20cancer%20cell%E2%80%93adipocyte%20interaction%2Fcrosstalk%20at%20the%20tumor%20invasive%20front&journal=Cancer%20Res.&volume=65&pages=10862-10871&publication_year=2005&author=Andarawewa%2CKL?
- What's the revenue for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15582574?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Matrix%20metalloproteinase%2011%20depletion%20inhibits%20cell%20proliferation%20in%20gastric%20cancer%20cells&journal=Biochem.%20Biophys.%20Res.%20Commun.&volume=326&pages=274-281&publication_year=2005&author=Deng%2CH&author=Guo%2CRF&author=Li%2CWM&author=Zhao%2CM&author=Lu%2CYY produce monthly?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15169894
- How much cash flow does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419866 have monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Diet-induced%20obesity%20and%20reduced%20skin%20cancer%20susceptibility%20in%20matrix%20metalloproteinase%2019-deficient%20mice&journal=Mol.%20Cell%20Biol.&volume=24&pages=5304-5313&publication_year=2004&author=Pendas%2CAM generate?
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11282999
- How much does http://scholar.google.com/scholar_lookup?&title=Subcellular%20distribution%20and%20cytokine-%20and%20chemokine-regulated%20secretion%20of%20leukolysin%2FMT6-MMP%2FMMP-25%20in%20neutrophils&journal=J.%20Biol.%20Chem.&volume=276&pages=21960-21968&publication_year=2001&author=Kang%2CT rake in every month?
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9740677?
- How much does http://scholar.google.com/scholar_lookup?&title=Isolation%20and%20characterization%20of%20two%20novel%20metalloproteinase%20genes%20linked%20to%20the%20Cdc2L%20locus%20on%20human%20chromosome%201p36.3&journal=Genomics&volume=52&pages=101-106&publication_year=1998&author=Gururajan%2CR&author=Grenet%2CJ&author=Lahti%2CJM&author=Kidd%2CVJ net monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15073121 earn?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Dysregulated%20expression%20of%20adamalysin-thrombospondin%20genes%20in%20human%20breast%20carcinoma&journal=Clin.%20Cancer%20Res.&volume=10&pages=2429-2440&publication_year=2004&author=Porter%2CS?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15928670 bring in each month?
- How much revenue does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361819 bring in?
- See how much http://scholar.google.com/scholar_lookup?&title=Identification%20of%20degradome%20components%20associated%20with%20prostate%20cancer%20progression%20by%20expression%20analysis%20of%20human%20prostatic%20tissues&journal=Br.%20J.%20Cancer&volume=92&pages=2171-2180&publication_year=2005&author=Riddick%2CAC makes per month
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11048948?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Epoxide%20electrophiles%20as%20activity-dependent%20cysteine%20protease%20profiling%20and%20discovery%20tools&journal=Chem.%20Biol.&volume=7&pages=569-581&publication_year=2000&author=Greenbaum%2CD&author=Medzihradszky%2CKF&author=Burlingame%2CA&author=Bogyo%2CM
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Mass%20spectrometry-based%20proteomics&journal=Nature&volume=422&pages=198-207&publication_year=2003&author=Abersold%2CR&author=Mann%2CM produce monthly?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Application%20of%20isotope%20dilution-mass%20spectrometry%20in%20clinical%20chemistry%2C%20pharmacokinetics%2C%20and%20toxicology&journal=Mass%20Spectrom.%20Rev.&volume=11&pages=249-307&publication_year=1992&author=De%20Leenheer%2CAP&author=Thienpont%2CLM?
- What's http://scholar.google.com/scholar_lookup?&title=Quantitative%20analysis%20of%20complex%20protein%20mixtures%20using%20isotope-coded%20affinity%20tags&journal=Nature%20Biotechnol.&volume=17&pages=994-999&publication_year=1999&author=Gygi%2CSP's gross income?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15220480's total income per month
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Activity-based%20probes%20for%20the%20proteomic%20profiling%20of%20metalloproteases&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&volume=101&pages=10000-10005&publication_year=2004&author=Saghatelian%2CA&author=Jessani%2CN&author=Joseph%2CA&author=Humphrey%2CM&author=Cravatt%2CBF
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12767177 generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Examination%20of%20novel%20zinc-binding%20groups%20for%20use%20in%20matrix%20metalloproteinase%20inhibitors&journal=Inorg.%20Chem.&volume=42&pages=3423-3430&publication_year=2003&author=Puerta%2CDT&author=Cohen%2CSM produce monthly?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14711305's financial summary
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Evaluation%20of%20P1%E2%80%B2-diversified%20phosphinic%20peptides%20leads%20to%20the%20development%20of%20highly%20selective%20inhibitors%20of%20MMP-11&journal=J.%20Med.%20Chem.&volume=47&pages=325-336&publication_year=2004&author=Matziari%2CM&author=Beau%2CF&author=Cuniasse%2CP&author=Dive%2CV&author=Yiotakis%2CA
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15781327 make?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Future%20challenges%20facing%20the%20development%20of%20specific%20active-site-directed%20synthetic%20inhibitors%20of%20MMPs&journal=Biochimie&volume=87&pages=393-402&publication_year=2005&author=Cuniasse%2CP each month?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15809432's financial summary
- How much income is http://scholar.google.com/scholar_lookup?&title=Conformational%20variability%20of%20matrix%20metalloproteinases%3A%20beyond%20a%20single%203D%20structure&journal=Proc.%20Natl%20Acad.%20Sci.%20USA&volume=102&pages=5334-5339&publication_year=2005&author=Bertini%2CI earning monthly?
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12392402?
- How much does http://scholar.google.com/scholar_lookup?&title=Impact%20of%20mobility%20on%20structure-based%20drug%20design%20for%20the%20MMPs&journal=J.%20Am.%20Chem.%20Soc.&volume=124&pages=12658-12659&publication_year=2002&author=Moy%2CFJ gross monthly?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15289103?
- Get to know http://scholar.google.com/scholar_lookup?&title=Crystal%20structures%20of%20novel%20non-peptidic%2C%20non-zinc%20chelating%20inhibitors%20bound%20to%20MMP-12&journal=J.%20Mol.%20Biol.&volume=341&pages=1063-1076&publication_year=2004&author=Morales%2CR's earnings
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16002291
- Get to know http://scholar.google.com/scholar_lookup?&title=Structure-based%20design%20and%20synthesis%20of%20novel%20non-zinc%20chelating%20MMP-12%20inhibitors&journal=Bioorg.%20Med.%20Chem.%20Lett.&volume=15&pages=3787-3790&publication_year=2005&author=Dublanchet%2CAC's earnings
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14732707's gross income?
- How much does http://scholar.google.com/scholar_lookup?&title=Similarity%20of%20binding%20sites%20of%20human%20matrix%20metalloproteinases&journal=J.%20Biol.%20Chem.&volume=279&pages=14194-14200&publication_year=2004&author=Lukacova%2CV pull in monthly?
- How much profit does https://citation-needed.springer.com/v2/references/10.1038/nrc1821?format=refman&flavour=references generate?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Christopher%20M.%20Overall pull in monthly?
- How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Christopher%20M.%20Overall%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
- How much profit is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Oded%20Kleifeld making per month?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Oded%20Kleifeld%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
- How much does http://www.cancer.gov/cancertopics/types/breast gross monthly?
- Income figures for http://www.cancerdegradome.org/
- http://www.clip.ubc.ca's revenue stream
- Learn about the earnings of http://www.uniovi.es/degradome/
- Profit of http://merops.sanger.ac.uk/
- Earnings of http://www.clip.ubc.ca/CLIP-CHIP.shtm
- How much does http://www.protease.org/ earn?
- How much does http://www.chem.qmul.ac.uk/iubmb/enzyme/EC34/ bring in each month?
- https://s100.copyright.com/AppDispatchServlet?title=Validating%20matrix%20metalloproteinases%20as%20drug%20targets%20and%20anti-targets%20for%20cancer%20therapy&author=Christopher%20M.%20Overall%20et%20al&contentID=10.1038%2Fnrc1821©right=Springer%20Nature%20Limited&publication=1474-175X&publicationDate=2006-03-01&publisherName=SpringerNature&orderBeanReset=true's revenue stream
- How much income is https://citation-needed.springer.com/v2/references/10.1038/nrc1821?format=refman&flavour=citation earning monthly?
- What's the profit of https://doi.org/10.1007/s13402-023-00857-y?
- How much does https://doi.org/10.1186/s12943-023-01714-0 generate monthly?
- How much cash flow does https://doi.org/10.1038/s41584-023-00966-w have monthly?
- What's the monthly income of https://doi.org/10.1038/s41598-023-32019-3?
- Get to know what's the income of https://doi.org/10.1038/s41598-021-90845-9
- How much does https://www.protocols.io/ net monthly?
- Discover the revenue of https://www.natureindex.com/
- Learn how profitable http://www.naturechina.com is on a monthly basis
- How much profit does https://www.natureasia.com/ja-jp make?
Analytics and Tracking {📊}
- Google Tag Manager
Libraries {📚}
- Foundation
- Isotope
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {📦}
- Crossref