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nature portfolio permissions reprints privacy policy research advertising social media intervening heavy-chain region constant heavy-chain region germinal center-derived memory author information authors activation-induced cytidine deaminase nature 460 nature 455 nature 429 nature 422 nature 448 nature transcription-targeted dna deamination exposing single-stranded dna vivo class-switch recombination author correspondence stat5 promotes accessibility batf3 deficiency reveals retroviruses bcl-6-gfp rv personal data central memory cd4+ class-switch recombination class switch recombination springerlink instant access gata-3-dependent enhancer activity data protection permissions cytolytic effector cd8+ transcription factor rorγt ap-1 mediated transcription s-region transcription ifn-γ reporters il-4 gene regulation lymphocyte attenuator regulates harvard medical school irf4 transcription factors class-switch assays transcription factors bcl-6 batf directly controlled additional factors regulate activator protein-1 activity privacy vivo antibody responses immune disease institute dysregulated immune responses

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         headline:The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
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      affiliation:
            name:Washington University School of Medicine
            address:
               name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
               type:PostalAddress
            type:Organization
      name:Kenneth M Murphy
      affiliation:
            name:Washington University School of Medicine
            address:
               name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
               type:PostalAddress
            type:Organization
            name:Howard Hughes Medical Institute
            address:
               name:Howard Hughes Medical Institute, St. Louis, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
      name:The Children's Hospital, the Immune Disease Institute and the Harvard Medical School, Boston, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
      name:The Children's Hospital, the Immune Disease Institute and the Harvard Medical School, Boston, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
      name:The Children's Hospital, the Immune Disease Institute and the Harvard Medical School, Boston, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
      name:The Children's Hospital, the Immune Disease Institute and the Harvard Medical School, Boston, USA
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, USA
      name:Howard Hughes Medical Institute, St. Louis, USA
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