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doi, pubmed, google, scholar, pmc, immunoglobulin, article, cells, gamma, free, transcripts, switch, cell, germline, switching, chain, heavy, class, alt, immunol, nlm, gene, expression, nature, recombination, production, coffman, structure, ncbi, search, mutant, heavychain, proc, natl, acad, sci, pnas, dna, science, feb, genes, embo, lymphocytes, image, interleukin, apr, rearrangement, epsilon, induced, lutzker,

Topics {✒️}

pmc beta search immunoglobulin heavy-chain switching heavy chain class-switching heavy-chain class switch cytokine-treated mouse splenocytes germ-line immunoglobulin intact c-fos gene igm-producing human neoplastic lymphokine directed class-switching heavy-chain switch mature germline transcripts class-switch recombination regions publisher site pdf germline epsilon transcripts immunoglobulin class switching rag-2 deficient blastocysts immunoglobulin class restriction gamma 2b gene immunoglobulin gene rearrangement il-4 transgenic mice directed class switching gamma 2b promoter gamma 2b exons class-switch recombination class switch recombination immunoglobulin deletion mutant license information pmcid important regulatory element embryonic stem cells cell differentiation induced transcripts initiate heterogeneously pmc disclaimer transcriptionally active dna elevated recombination rates cell-derived lymphokine lipopolysaccharide-directed switching united states government mutated chromosome retains mutant es cells annu rev genet humoral immune functions es-cell derived constant region locus igh enhancer region constant-region genes human n-myc igg-producing cells additional studies demonstrated single targeting construct article image

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