NATURE . COM {}

Matching Content Categories {📚}

• Science
• Education
• Social Networks

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,554,915 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}

Display Ads {🎯}

Direct Advertisers (10)

Reseller Advertisers (38)

How Much Does Nature.com Make? {💰}

Display Ads {🎯}

$536,300 per month
Our estimates place Nature.com's monthly online earnings from display ads at $357,503 to $983,134.

Keywords {🔍}

cells, vdr, cancer, cell, vitamin, growth, bone, breast, article, expression, google, scholar, knockdown, figure, cas, signaling, reduced, tumor, mdavdrkd, mdant, receptor, prostate, ohd, βcatenin, apoptosis, compared, levels, tumors, increased, protein, genes, effects, usa, human, controls, proliferation, pathway, data, mice, nuclear, treatment, mdamb, vitro, significantly, nature, wntβcatenin, vivo, vdrkd, analysis, deficiency,

Topics {✒️}

nature portfolio vectastain abc-peroxidase kits privacy policy activates wnt/beta-catenin signaling nature 2010 nature maintain wnt/β-catenin signaling wnt/β-catenin signaling pathway advertising wnt/β-catenin signaling plays triple negative/basal wnt/β-catenin signalling pathway anzac research institute wnt/β-catenin pathway wnt/β-catenin signaling index 0/ reprints mda-vdr-kd cells demonstrated stabilizes β-catenin signaling vdr-expressing mda-nt cells β-catenin protein levels mda-mb-231 cells reduces enhance β-catenin levels open targeting beta-catenin signaling mda-vdr-kd cells compared methyl donor s-adenosylmethionine real-time rt–pcr real-time rt-pcr parathyroid hormone secretion—induces pc3-vdr-kd cells compared micro-computed tomography imaging wnt/β-catenin activation potent anti-resorptive treatments tartrate-resistant acid phosphatase chronic high-fat diet representative micro-computed tomography minimize post-surgical pain 2d3-treated mda-nt cells exert strong anti-proliferative author correspondence gsk-3β protein levels clinical research vitamin d-responsive elements vitamin d-replete mice mda-nt cell lines bone research mda-vdr-kd cells gsk-3-selective inhibitors derived vitamin d-dependent recruitment

Questions {❓}

• Vitamin D and prevention of cancer - ready for prime time?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Loss of the vitamin D receptor in human breast and prostate cancers strongly induces cell apoptosis through downregulation of Wnt/β-catenin signaling
         description:Vitamin D co-regulates cell proliferation, differentiation and apoptosis in numerous tissues, including cancers. The known anti-proliferative and pro-apoptotic actions of the active metabolite of vitamin D, 1,25-dihydroxy-vitamin D [1,25(OH)2D] are mediated through binding to the vitamin D receptor (VDR). Here, we report on the unexpected finding that stable knockdown of VDR expression in the human breast and prostate cancer cell lines, MDA-MB-231 and PC3, strongly induces cell apoptosis and inhibits cell proliferation in vitro. Implantation of these VDR knockdown cells into the mammary fat pad (MDA-MB-231), subcutaneously (PC3) or intra-tibially (both cell lines) in immune-incompetent nude mice resulted in reduced tumor growth associated with increased apoptosis and reduced cell proliferation compared with controls. These growth-retarding effects of VDR knockdown occur in the presence and absence of vitamin D and are independent of whether cells were grown in bone or soft tissues. Transcriptome analysis of VDR knockdown and non-target control cell lines demonstrated that loss of the VDR was associated with significant attenuation in the Wnt/β-catenin signaling pathway. In particular, cytoplasmic and nuclear β-catenin protein levels were reduced with a corresponding downregulation of downstream genes such as Axin2, Cyclin D1, interleukin-6 (IL-6), and IL-8. Stabilization of β-catenin using the GSK-3β inhibitor BIO partly reversed the growth-retarding effects of VDR knockdown. Our results indicate that the unliganded VDR possesses hitherto unknown functions to promote breast and prostate cancer growth, which appear to be operational not only within but also outside the bone environment. These novel functions contrast with the known anti-proliferative nuclear actions of the liganded VDR and may represent targets for new diagnostic and therapeutic approaches in breast and prostate cancer. Blockade of the cellular receptor for vitamin D may help shrink tumors that have spread to bone tissue. Markus Seibel from the ANZAC Research Institute in Sydney, Australia, and colleagues experimentally lowered the expression of the gene encoding the vitamin D receptor (VDR) in both human breast and prostate cancer cell lines. These altered cells had a reduced growth rate and an elevated death rate, both in cell culture and when implanted into mice, whether they were inserted into the breast, under the skin, or into the bone. These growth-retarding effects occurred whether vitamin D was present or not. Activation of VDR with vitamin D was previously shown to have similar effects, suggesting that either blocking VDR or activating it can lead to the same outcome: reduced tumor growth, including tumors that have spread to bone.
         datePublished:2017-09-05T00:00:00Z
         dateModified:2017-09-05T00:00:00Z
         pageStart:1
         pageEnd:12
         license:http://creativecommons.org/licenses/by/4.0/
         sameAs:https://doi.org/10.1038/boneres.2017.23
         keywords:
            Bone cancer
            Cancer
            Medicine/Public Health
            general
            Internal Medicine
            Orthopedics
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig4_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig5_HTML.jpg
         isPartOf:
            name:Bone Research
            issn:
               2095-6231
            volumeNumber:5
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Yu Zheng
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Trupti Trivedi
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ruby CY Lin
               affiliation:
                     name:Asbestos Diseases Research Institute, Cardiothoracic Genomics
                     address:
                        name:Asbestos Diseases Research Institute, Cardiothoracic Genomics, Sydney, Australia
                        type:PostalAddress
                     type:Organization
                     name:School of Medical Sciences, University of New South Wales
                     address:
                        name:School of Medical Sciences, University of New South Wales, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Colette Fong-Yee
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Rick Nolte
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jeline Manibo
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Yunzhao Chen
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
                     name:Shihezi University School of Medicine
                     address:
                        name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Musharraf Hossain
               affiliation:
                     name:Shihezi University School of Medicine
                     address:
                        name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Konstantin Horas
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Colin Dunstan
               affiliation:
                     name:Biomedical Engineering, AMME, University of Sydney
                     address:
                        name:Biomedical Engineering, AMME, University of Sydney, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hong Zhou
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
                     name:Concord Clinical School, The University of Sydney
                     address:
                        name:Concord Clinical School, The University of Sydney, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Markus J Seibel
               affiliation:
                     name:Bone Research Program, ANZAC Research Institute
                     address:
                        name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                        type:PostalAddress
                     type:Organization
                     name:Concord Clinical School, The University of Sydney
                     address:
                        name:Concord Clinical School, The University of Sydney, Sydney, Australia
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Loss of the vitamin D receptor in human breast and prostate cancers strongly induces cell apoptosis through downregulation of Wnt/β-catenin signaling
      description:Vitamin D co-regulates cell proliferation, differentiation and apoptosis in numerous tissues, including cancers. The known anti-proliferative and pro-apoptotic actions of the active metabolite of vitamin D, 1,25-dihydroxy-vitamin D [1,25(OH)2D] are mediated through binding to the vitamin D receptor (VDR). Here, we report on the unexpected finding that stable knockdown of VDR expression in the human breast and prostate cancer cell lines, MDA-MB-231 and PC3, strongly induces cell apoptosis and inhibits cell proliferation in vitro. Implantation of these VDR knockdown cells into the mammary fat pad (MDA-MB-231), subcutaneously (PC3) or intra-tibially (both cell lines) in immune-incompetent nude mice resulted in reduced tumor growth associated with increased apoptosis and reduced cell proliferation compared with controls. These growth-retarding effects of VDR knockdown occur in the presence and absence of vitamin D and are independent of whether cells were grown in bone or soft tissues. Transcriptome analysis of VDR knockdown and non-target control cell lines demonstrated that loss of the VDR was associated with significant attenuation in the Wnt/β-catenin signaling pathway. In particular, cytoplasmic and nuclear β-catenin protein levels were reduced with a corresponding downregulation of downstream genes such as Axin2, Cyclin D1, interleukin-6 (IL-6), and IL-8. Stabilization of β-catenin using the GSK-3β inhibitor BIO partly reversed the growth-retarding effects of VDR knockdown. Our results indicate that the unliganded VDR possesses hitherto unknown functions to promote breast and prostate cancer growth, which appear to be operational not only within but also outside the bone environment. These novel functions contrast with the known anti-proliferative nuclear actions of the liganded VDR and may represent targets for new diagnostic and therapeutic approaches in breast and prostate cancer. Blockade of the cellular receptor for vitamin D may help shrink tumors that have spread to bone tissue. Markus Seibel from the ANZAC Research Institute in Sydney, Australia, and colleagues experimentally lowered the expression of the gene encoding the vitamin D receptor (VDR) in both human breast and prostate cancer cell lines. These altered cells had a reduced growth rate and an elevated death rate, both in cell culture and when implanted into mice, whether they were inserted into the breast, under the skin, or into the bone. These growth-retarding effects occurred whether vitamin D was present or not. Activation of VDR with vitamin D was previously shown to have similar effects, suggesting that either blocking VDR or activating it can lead to the same outcome: reduced tumor growth, including tumors that have spread to bone.
      datePublished:2017-09-05T00:00:00Z
      dateModified:2017-09-05T00:00:00Z
      pageStart:1
      pageEnd:12
      license:http://creativecommons.org/licenses/by/4.0/
      sameAs:https://doi.org/10.1038/boneres.2017.23
      keywords:
         Bone cancer
         Cancer
         Medicine/Public Health
         general
         Internal Medicine
         Orthopedics
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig4_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fboneres.2017.23/MediaObjects/41413_2017_Article_BFboneres201723_Fig5_HTML.jpg
      isPartOf:
         name:Bone Research
         issn:
            2095-6231
         volumeNumber:5
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Yu Zheng
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Trupti Trivedi
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ruby CY Lin
            affiliation:
                  name:Asbestos Diseases Research Institute, Cardiothoracic Genomics
                  address:
                     name:Asbestos Diseases Research Institute, Cardiothoracic Genomics, Sydney, Australia
                     type:PostalAddress
                  type:Organization
                  name:School of Medical Sciences, University of New South Wales
                  address:
                     name:School of Medical Sciences, University of New South Wales, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Colette Fong-Yee
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Rick Nolte
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jeline Manibo
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Yunzhao Chen
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
                  name:Shihezi University School of Medicine
                  address:
                     name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Musharraf Hossain
            affiliation:
                  name:Shihezi University School of Medicine
                  address:
                     name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Konstantin Horas
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Colin Dunstan
            affiliation:
                  name:Biomedical Engineering, AMME, University of Sydney
                  address:
                     name:Biomedical Engineering, AMME, University of Sydney, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hong Zhou
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
                  name:Concord Clinical School, The University of Sydney
                  address:
                     name:Concord Clinical School, The University of Sydney, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Markus J Seibel
            affiliation:
                  name:Bone Research Program, ANZAC Research Institute
                  address:
                     name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
                     type:PostalAddress
                  type:Organization
                  name:Concord Clinical School, The University of Sydney
                  address:
                     name:Concord Clinical School, The University of Sydney, Sydney, Australia
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Bone Research
      issn:
         2095-6231
      volumeNumber:5
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Asbestos Diseases Research Institute, Cardiothoracic Genomics
      address:
         name:Asbestos Diseases Research Institute, Cardiothoracic Genomics, Sydney, Australia
         type:PostalAddress
      name:School of Medical Sciences, University of New South Wales
      address:
         name:School of Medical Sciences, University of New South Wales, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Shihezi University School of Medicine
      address:
         name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
         type:PostalAddress
      name:Shihezi University School of Medicine
      address:
         name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Biomedical Engineering, AMME, University of Sydney
      address:
         name:Biomedical Engineering, AMME, University of Sydney, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Concord Clinical School, The University of Sydney
      address:
         name:Concord Clinical School, The University of Sydney, Sydney, Australia
         type:PostalAddress
      name:Bone Research Program, ANZAC Research Institute
      address:
         name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
         type:PostalAddress
      name:Concord Clinical School, The University of Sydney
      address:
         name:Concord Clinical School, The University of Sydney, Sydney, Australia
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Yu Zheng
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Trupti Trivedi
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Ruby CY Lin
      affiliation:
            name:Asbestos Diseases Research Institute, Cardiothoracic Genomics
            address:
               name:Asbestos Diseases Research Institute, Cardiothoracic Genomics, Sydney, Australia
               type:PostalAddress
            type:Organization
            name:School of Medical Sciences, University of New South Wales
            address:
               name:School of Medical Sciences, University of New South Wales, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Colette Fong-Yee
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Rick Nolte
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Jeline Manibo
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Yunzhao Chen
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
            name:Shihezi University School of Medicine
            address:
               name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
               type:PostalAddress
            type:Organization
      name:Musharraf Hossain
      affiliation:
            name:Shihezi University School of Medicine
            address:
               name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
               type:PostalAddress
            type:Organization
      name:Konstantin Horas
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Colin Dunstan
      affiliation:
            name:Biomedical Engineering, AMME, University of Sydney
            address:
               name:Biomedical Engineering, AMME, University of Sydney, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Hong Zhou
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
            name:Concord Clinical School, The University of Sydney
            address:
               name:Concord Clinical School, The University of Sydney, Sydney, Australia
               type:PostalAddress
            type:Organization
      name:Markus J Seibel
      affiliation:
            name:Bone Research Program, ANZAC Research Institute
            address:
               name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
               type:PostalAddress
            type:Organization
            name:Concord Clinical School, The University of Sydney
            address:
               name:Concord Clinical School, The University of Sydney, Sydney, Australia
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Asbestos Diseases Research Institute, Cardiothoracic Genomics, Sydney, Australia
      name:School of Medical Sciences, University of New South Wales, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
      name:Department of Pathology, Shihezi University School of Medicine, Shihezi, China
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Biomedical Engineering, AMME, University of Sydney, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Concord Clinical School, The University of Sydney, Sydney, Australia
      name:Bone Research Program, ANZAC Research Institute, Sydney, Australia
      name:Concord Clinical School, The University of Sydney, Sydney, Australia

External Links {🔗}(132)

• Learn about the earnings of https://doi.org/10.1158%2F1078-0432.CCR-08-2179
• How profitable is http://scholar.google.com/scholar_lookup?&title=Tumor%20microenvironment%20of%20metastasis%20in%20human%20breast%20carcinoma%3A%20a%20potential%20prognostic%20marker%20linked%20to%20hematogenous%20dissemination&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-08-2179&volume=15&pages=2433-2441&publication_year=2009&author=Robinson%2CBD&author=Sica%2CGL&author=Liu%2CYF?
• How much revenue does https://doi.org/10.1038%2Fnrc867 produce monthly?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Metastasis%20to%20bone%3A%20causes%2C%20consequences%20and%20therapeutic%20opportunities&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc867&volume=2&pages=584-593&publication_year=2002&author=Mundy%2CGR?
• Check the income stats for https://doi.org/10.1038%2Fnrc3055
• How much income is http://scholar.google.com/scholar_lookup?&title=Cancer%20to%20bone%3A%20a%20fatal%20attraction&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc3055&volume=11&pages=411-425&publication_year=2011&author=Weilbaecher%2CKN&author=Guise%2CTA&author=McCauley%2CLK earning monthly?
• How much does https://doi.org/10.1016%2Fj.bone.2010.05.007 make?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20bone%20remodeling%20environment%20is%20a%20factor%20in%20breast%20cancer%20bone%20metastasis&journal=Bone&doi=10.1016%2Fj.bone.2010.05.007&volume=48&pages=66-70&publication_year=2011&author=Ooi%2CLL&author=Zheng%2CY&author=Stalgis-Bilinski%2CK gross monthly?
• Find out how much https://doi.org/10.1016%2Fj.jbo.2012.11.002 earns monthly
• http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20the%20bone%20microenvironment%20in%20skeletal%20metastasis&journal=J%20Bone%20Oncol&doi=10.1016%2Fj.jbo.2012.11.002&volume=2&pages=47-57&publication_year=2013&author=Zheng%2CY&author=Zhou%2CH&author=Dunstan%2CC's revenue stream
• How much cash flow does https://link.springer.com/doi/10.1007/s10585-014-9680-3 have monthly?
• How much income is http://scholar.google.com/scholar_lookup?&title=Targeting%20IL-6%20and%20RANKL%20signaling%20inhibits%20prostate%20cancer%20growth%20in%20bone&journal=Clin%20Exp%20Metastasis&doi=10.1007%2Fs10585-014-9680-3&volume=31&pages=921-933&publication_year=2014&author=Zheng%2CY&author=Basel%2CD&author=Chow%2CSO earning monthly?
• How profitable is https://link.springer.com/doi/10.1007/s10585-008-9172-4?
• How much profit does http://scholar.google.com/scholar_lookup?&title=Bone%20resorption%20increases%20tumour%20growth%20in%20a%20mouse%20model%20of%20osteosclerotic%20breast%20cancer%20metastasis&journal=Clin%20Exp%20Metastasis&doi=10.1007%2Fs10585-008-9172-4&volume=25&pages=559-567&publication_year=2008&author=Zheng%2CY&author=Zhou%2CH&author=Fong-Yee%2CC generate?
• What's the financial outcome of https://doi.org/10.1002%2Fpros.21316?
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20deficiency%20promotes%20prostate%20cancer%20growth%20in%20bone&journal=Prostate&doi=10.1002%2Fpros.21316&volume=71&pages=1012-1021&publication_year=2011&author=Zheng%2CY&author=Zhou%2CH&author=Ooi%2CLL
• How much profit is https://doi.org/10.1158%2F0008-5472.CAN-07-1046 making per month?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Accelerated%20bone%20resorption%2C%20due%20to%20dietary%20calcium%20deficiency%2C%20promotes%20breast%20cancer%20tumor%20growth%20in%20bone&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-07-1046&volume=67&pages=9542-9548&publication_year=2007&author=Zheng%2CY&author=Zhou%2CH&author=Modzelewski%2CJR generate?
• How much profit is https://doi.org/10.1158%2F0008-5472.CAN-09-3194 making per month?
• How much does http://scholar.google.com/scholar_lookup?&title=Vitamin%20d%20deficiency%20promotes%20human%20breast%20cancer%20growth%20in%20a%20murine%20model%20of%20bone%20metastasis&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-09-3194&volume=70&pages=1835-1844&publication_year=2010&author=Ooi%2CLL&author=Zhou%2CH&author=Kalak%2CR earn?
• See how much https://doi.org/10.1200%2FJCO.2005.06.091 makes per month
• Learn how profitable http://scholar.google.com/scholar_lookup?&title=Predictive%20value%20of%20bone%20resorption%20and%20formation%20markers%20in%20cancer%20patients%20with%20bone%20metastases%20receiving%20the%20bisphosphonate%20zoledronic%20acid&journal=J%20Clin%20Oncol&doi=10.1200%2FJCO.2005.06.091&volume=23&pages=4925-4935&publication_year=2005&author=Coleman%2CRE is on a monthly basis
• What is the earnings of https://link.springer.com/doi/10.1007/s00198-013-2530-3?
• http://scholar.google.com/scholar_lookup?&title=Cancer-associated%20bone%20disease&journal=Osteoporos%20Int&doi=10.1007%2Fs00198-013-2530-3&volume=24&pages=2929-2953&publication_year=2013&author=Rizzoli%2CR&author=Body%2CJJ&author=Brandi%2CML's revenue stream
• Income figures for https://doi.org/10.1016%2Fj.bone.2010.07.012
• How much does http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20deficiency%20promotes%20growth%20of%20MCF-7%20human%20breast%20cancer%20in%20a%20rodent%20model%20of%20osteosclerotic%20bone%20metastasis&journal=Bone&doi=10.1016%2Fj.bone.2010.07.012&volume=47&pages=795-803&publication_year=2010&author=Ooi%2CLL&author=Zheng%2CY&author=Zhou%2CH pull in monthly?
• How much does https://doi.org/10.1017%2FS0029665108006964 bring in each month?
• How much does http://scholar.google.com/scholar_lookup?&title=The%20vitamin%20D%20receptor%20in%20cancer&journal=Proc%20Nutr%20Soc&doi=10.1017%2FS0029665108006964&volume=67&pages=115-127&publication_year=2008&author=Thorne%2CJ&author=Campbell%2CMJ gross monthly?
• What's the monthly money flow for https://doi.org/10.1111%2Fj.1600-0625.2010.01202.x?
• How much does http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%3A%20an%20ancient%20hormone&journal=Exp%20Dermatol&doi=10.1111%2Fj.1600-0625.2010.01202.x&volume=20&pages=7-13&publication_year=2010&author=Bikle%2CDD earn?
• How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1846309?
• Explore the financials of http://scholar.google.com/scholar_lookup?&title=Immunocytochemical%20determination%20of%20estrogen%20receptor%2C%20progesterone%20receptor%2C%20and%201%2C25-dihydroxyvitamin%20D3%20receptor%20in%20breast%20cancer%20and%20relationship%20to%20prognosis&journal=Cancer%20Res&volume=51&pages=239-244&publication_year=1991&author=Berger%2CU&author=McClelland%2CRA&author=Wilson%2CP
• What's the monthly money flow for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=2824042?
• What's http://scholar.google.com/scholar_lookup?&title=Immunocytochemical%20detection%20of%201%2C25-dihydroxyvitamin%20D3%20receptor%20in%20breast%20cancer&journal=Cancer%20Res&volume=47&pages=6793-6799&publication_year=1987&author=Berger%2CU&author=Wilson%2CP&author=McClelland%2CRA's gross income?
• How much money does https://doi.org/10.1369%2F0022155411429155 generate?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20Association%20Between%20Vitamin%20D%20Receptor%20Expression%20and%20Prolonged%20Overall%20Survival%20in%20Breast%20Cancer&journal=J%20Histochem%20Cytochem&doi=10.1369%2F0022155411429155&volume=60&pages=121-129&publication_year=2011&author=Ditsch%2CN&author=Toth%2CB&author=Mayr%2CD produce monthly?
• What is the earnings of https://doi.org/10.1016%2FS0303-7207%2802%2900416-1?
• http://scholar.google.com/scholar_lookup?&title=Characterization%20of%20mammary%20tumor%20cell%20lines%20from%20wild%20type%20and%20vitamin%20D%203%20receptor%20knockout%20mice&journal=Mol%20Cell%20Endocrinol&doi=10.1016%2FS0303-7207%2802%2900416-1&volume=200&pages=67-80&publication_year=2003&author=Zinser%2CGM&author=McEleney%2CK&author=Welsh%2CJ's total income per month
• How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20vitamin%20D%20receptor%3A%20a%20tumor%20suppressor%20in%20skin&journal=Discov%20Med&volume=11&pages=7-17&publication_year=2010&author=Bikle%2CDD produce monthly?
• Learn about the earnings of https://doi.org/10.1359%2Fjbmr.2001.16.8.1486
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=A%20bone-seeking%20clone%20exhibits%20different%20biological%20properties%20from%20the%20MDA-MB-231%20parental%20human%20breast%20cancer%20cells%20and%20a%20brain-seeking%20clone%20in%20vivo%20and%20in%20vitro&journal=J%20Bone%20Miner%20Res&doi=10.1359%2Fjbmr.2001.16.8.1486&volume=16&pages=1486-1495&publication_year=2001&author=Yoneda%2CT&author=Williams%2CPJ&author=Hiraga%2CT?
• See how much https://doi.org/10.1002%2Fjbmr.2231 makes per month
• How much does http://scholar.google.com/scholar_lookup?&title=Direct%20crosstalk%20between%20cancer%20and%20osteoblast%20lineage%20cells%20fuels%20metastatic%20growth%20in%20bone%20via%20auto-amplification%20of%20IL-6%20and%20RANKL%20signaling%20pathways&journal=J%20Bone%20Miner%20Res&doi=10.1002%2Fjbmr.2231&volume=29&pages=1938-1949&publication_year=2014&author=Zheng%2CY&author=Chow%2CSO&author=Boernert%2CK rake in every month?
• What's https://doi.org/10.1016%2Fj.chembiol.2003.11.010's gross income?
• What's the revenue for http://scholar.google.com/scholar_lookup?&title=GSK-3-selective%20inhibitors%20derived%20from%20Tyrian%20purple%20indirubins&journal=Chem%20Biol&doi=10.1016%2Fj.chembiol.2003.11.010&volume=10&pages=1255-1266&publication_year=2003&author=Meijer%2CL&author=Skaltsounis%2CAL&author=Magiatis%2CP?
• How much does https://doi.org/10.1038%2Fnature09491 rake in every month?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Chronic%20high-fat%20diet%20in%20fathers%20programs%20beta-cell%20dysfunction%20in%20female%20rat%20offspring&journal=Nature&doi=10.1038%2Fnature09491&volume=467&pages=963-966&publication_year=2010&author=Ng%2CS&author=Lin%2CR&author=Laybutt%2CD?
• Financial intake of https://doi.org/10.1111%2Fj.1432-0436.2006.00131.x
• How much does http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20regulates%20the%20phenotype%20of%20human%20breast%20cancer%20cells&journal=Differentiation&doi=10.1111%2Fj.1432-0436.2006.00131.x&volume=75&pages=193-207&publication_year=2007&author=Pendas-Franco%2CN&author=Gonzalez-Sancho%2CJM&author=Suarez%2CY pull in monthly?
• What's the financial outcome of https://link.springer.com/doi/10.1186/1472-6882-13-203?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Targeting%20beta-catenin%20signaling%20to%20induce%20apoptosis%20in%20human%20breast%20cancer%20cells%20by%20z-guggulsterone%20and%20Gugulipid%20extract%20of%20Ayurvedic%20medicine%20plant%20Commiphora%20mukul&journal=BMC%20Complement%20Altern%20Med&doi=10.1186%2F1472-6882-13-203&volume=13&publication_year=2013&author=Jiang%2CG&author=Xiao%2CX&author=Zeng%2CY produce monthly?
• https://doi.org/10.1016%2Fj.yexcr.2015.09.003's total income per month
• Find out how much http://scholar.google.com/scholar_lookup?&title=The%20beta-catenin%20signaling%20pathway%20induces%20aggressive%20potential%20in%20breast%20cancer%20by%20up-regulating%20the%20chemokine%20CCL5&journal=Exp%20Cell%20Res&doi=10.1016%2Fj.yexcr.2015.09.003&volume=338&pages=22-31&publication_year=2015&author=Yasuhara%2CR&author=Irie%2CT&author=Suzuki%2CK earns monthly
• http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26992223's financial summary
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029685's total income per month
• How much does http://scholar.google.com/scholar_lookup?&title=MicroRNA-1229%20overexpression%20promotes%20cell%20proliferation%20and%20tumorigenicity%20and%20activates%20Wnt%2Fbeta-catenin%20signaling%20in%20breast%20cancer&journal=Oncotarget&volume=7&pages=24076-24087&publication_year=2016&author=Tan%2CZ&author=Zheng%2CH&author=Liu%2CX pull in?
• How much does https://doi.org/10.1016%2Fj.celrep.2014.12.045 earn?
• How much money does http://scholar.google.com/scholar_lookup?&title=A%20vitamin%20d%20receptor%20selectively%20activated%20by%20gemini%20analogs%20reveals%20ligand%20dependent%20and%20independent%20effects&journal=Cell%20Rep&doi=10.1016%2Fj.celrep.2014.12.045&volume=10&pages=516-526&publication_year=2015&author=Huet%2CT&author=Laverny%2CG&author=Ciesielski%2CF make?
• How much income is https://doi.org/10.1074%2Fjbc.M003791200 earning monthly?
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Dimerization%20with%20retinoid%20X%20receptors%20promotes%20nuclear%20localization%20and%20subnuclear%20targeting%20of%20vitamin%20D%20receptors&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M003791200&volume=275&pages=41114-41123&publication_year=2000&author=Prufer%2CK&author=Racz%2CA&author=Lin%2CGC produce monthly?
• https://doi.org/10.1128%2FMCB.01909-07's financial summary
• Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Vitamin%20D-dependent%20recruitment%20of%20corepressors%20to%20vitamin%20D%2Fretinoid%20X%20receptor%20heterodimers&journal=Mol%20Cell%20Biol&doi=10.1128%2FMCB.01909-07&volume=28&pages=3817-3829&publication_year=2008&author=Sanchez-Martinez%2CR&author=Zambrano%2CA&author=Castillo%2CAI
• How much revenue does https://doi.org/10.1006%2Fbbrc.1998.9799 bring in?
• Get to know http://scholar.google.com/scholar_lookup?&title=The%20interaction%20of%20the%20vitamin%20D%20receptor%20with%20nuclear%20receptor%20corepressors%20and%20coactivators&journal=Biochem%20Biophys%20Res%20Commun&doi=10.1006%2Fbbrc.1998.9799&volume=253&pages=358-363&publication_year=1998&author=Tagami%2CT&author=Lutz%2CWH&author=Kumar%2CR's earnings
• What's the income of https://doi.org/10.1677%2Fjme.0.0200327?
• http://scholar.google.com/scholar_lookup?&title=Repression%20of%20basal%20transcription%20by%20vitamin%20D%20receptor%3A%20evidence%20for%20interaction%20of%20unliganded%20vitamin%20D%20receptor%20with%20two%20receptor%20interaction%20domains%20in%20RIP13delta1&journal=J%20Mol%20Endocrinol&doi=10.1677%2Fjme.0.0200327&volume=20&pages=327-335&publication_year=1998&author=Dwivedi%2CPP&author=Muscat%2CGE&author=Bailey%2CPJ's total income per month
• https://doi.org/10.1016%2Fj.jsbmb.2004.03.078 income
• Income figures for http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20receptor%20B1%20and%20exon%201d%3A%20functional%20and%20evolutionary%20analysis&journal=J%20Steroid%20Biochem%20Mol%20Biol&doi=10.1016%2Fj.jsbmb.2004.03.078&volume=89-90&pages=233-238&publication_year=2004&author=Gardiner%2CEM&author=Esteban%2CLM&author=Fong%2CC
• https://doi.org/10.1210%2Fme.2001-0345's revenue stream
• How much cash flow does http://scholar.google.com/scholar_lookup?&title=Retinoid%20X%20receptor%20dominates%20the%20nuclear%20import%20and%20export%20of%20the%20unliganded%20vitamin%20D%20receptor&journal=Mol%20Endocrinol&doi=10.1210%2Fme.2001-0345&volume=16&pages=1738-1751&publication_year=2002&author=Prufer%2CK&author=Barsony%2CJ have monthly?
• https://doi.org/10.1016%2Fbs.vh.2015.10.011's revenue stream
• How much money does http://scholar.google.com/scholar_lookup?&title=Genomic%20determinants%20of%20vitamin%20D-regulated%20gene%20expression&journal=Vitam%20Horm&doi=10.1016%2Fbs.vh.2015.10.011&volume=100&pages=21-44&publication_year=2016&author=Pike%2CJW&author=Meyer%2CMB&author=Benkusky%2CNA make?
• How much does https://doi.org/10.1073%2Fpnas.0702884104 pull in?
• Financial intake of http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20receptor%20is%20essential%20for%20normal%20keratinocyte%20stem%20cell%20function&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.0702884104&volume=104&pages=9428-9433&publication_year=2007&author=Cianferotti%2CL&author=Cox%2CM&author=Skorija%2CK
• How much profit does https://doi.org/10.1016%2Fj.yexcr.2010.02.001 make?
• What is the earnings of http://scholar.google.com/scholar_lookup?&title=Cross-regulation%20of%20signaling%20pathways%3A%20an%20example%20of%20nuclear%20hormone%20receptors%20and%20the%20canonical%20Wnt%20pathway&journal=Exp%20Cell%20Res&doi=10.1016%2Fj.yexcr.2010.02.001&volume=316&pages=1763-1772&publication_year=2010&author=Beildeck%2CME&author=Gelmann%2CEP&author=Byers%2CSW?
• How much does https://doi.org/10.1172%2FJCI70941 net monthly?
• How much income does http://scholar.google.com/scholar_lookup?&title=Taxonomy%20of%20breast%20cancer%20based%20on%20normal%20cell%20phenotype%20predicts%20outcome&journal=J%20Clin%20Invest&doi=10.1172%2FJCI70941&volume=124&pages=859-870&publication_year=2014&author=Santagata%2CS&author=Thakkar%2CA&author=Ergonul%2CA have?
• Get to know what's the income of https://link.springer.com/doi/10.1186/1471-2407-10-483
• How much revenue does http://scholar.google.com/scholar_lookup?&title=Alterations%20in%20Vitamin%20D%20signalling%20and%20metabolic%20pathways%20in%20breast%20cancer%20progression%3A%20a%20study%20of%20VDR%2C%20CYP27B1%20and%20CYP24A1%20expression%20in%20benign%20%26%20malignant%20breast%20lesions&journal=BMC%20Cancer&doi=10.1186%2F1471-2407-10-483&volume=10&publication_year=2010&author=Lopes%2CN&author=Sousa%2CB&author=Martins%2CD produce monthly?
• How much profit does https://doi.org/10.1023%2FA%3A1021343825552 generate?
• What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Analysis%20of%20vitamin%20D-receptor%20%28VDR%29%20and%20retinoid%20X-receptor%20alpha%20in%20breast%20cancer&journal=Histochem%20J&doi=10.1023%2FA%3A1021343825552&volume=34&pages=35-40&publication_year=2002&author=Friedrich%2CM&author=Axt-Fliedner%2CR&author=Villena-Heinsen%2CC?
• How much does https://doi.org/10.1016%2Fj.jsbmb.2013.10.022 bring in each month?
• What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Modeling%20vitamin%20D%20actions%20in%20triple%20negative%2Fbasal-like%20breast%20cancer&journal=J%20Steroid%20Biochem%20Mol%20Biol&doi=10.1016%2Fj.jsbmb.2013.10.022&volume=144&pages=65-73&publication_year=2014&author=LaPorta%2CE&author=Welsh%2CJ?
• How much does https://doi.org/10.1158%2F1078-0432.CCR-04-2359 make?
• How much does http://scholar.google.com/scholar_lookup?&title=Autocrine%20metabolism%20of%20vitamin%20D%20in%20normal%20and%20malignant%20breast%20tissue&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-04-2359&volume=11&pages=3579-3586&publication_year=2005&author=Townsend%2CK&author=Banwell%2CCM&author=Guy%2CM generate monthly?
• What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=26008979?
• Get to know what's the income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599271
• What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Vitamin%20D3-dependent%20VDR%20signaling%20delays%20ron-mediated%20breast%20tumorigenesis%20through%20suppression%20of%20beta-catenin%20activity&journal=Oncotarget&volume=6&pages=16304-16320&publication_year=2015&author=Johnson%2CAL&author=Zinser%2CGM&author=Waltz%2CSE?
• What's the income generated by https://doi.org/10.1056%2FNEJMp1102022 each month?
• Profit of http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20and%20prevention%20of%20cancer%20-%20ready%20for%20prime%20time%3F&journal=N%20Engl%20J%20Med&doi=10.1056%2FNEJMp1102022&volume=364&pages=1385-1387&publication_year=2011&author=Manson%2CJE&author=Mayne%2CST&author=Clinton%2CSK
• How much revenue does https://doi.org/10.2174%2F187152013804487362 generate?
• How much money does http://scholar.google.com/scholar_lookup?&title=Vitamin%20D%20and%20breast%20cancer%20incidence%20and%20outcome&journal=Anticancer%20Agents%20Med%20Chem&doi=10.2174%2F187152013804487362&volume=13&pages=98-106&publication_year=2013&author=Chlebowski%2CRT generate?
• Earnings of https://doi.org/10.1016%2Fj.abb.2012.02.016
• How much does http://scholar.google.com/scholar_lookup?&title=Extrarenal%20expression%20of%20the%2025-hydroxyvitamin%20D-1-hydroxylase&journal=Arch%20Biochem%20Biophys&doi=10.1016%2Fj.abb.2012.02.016&volume=523&pages=95-102&publication_year=2012&author=Adams%2CJS&author=Hewison%2CM pull in monthly?
• How much does https://citation-needed.springer.com/v2/references/10.1038/boneres.2017.23?format=refman&flavour=references pull in monthly?
• Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yu%20Zheng
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yu%20Zheng%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
• How much cash flow does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Trupti%20Trivedi have monthly?
• Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Trupti%20Trivedi%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Ruby%20CY%20Lin earns monthly
• Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Ruby%20CY%20Lin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Colette%20Fong-Yee income
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Colette%20Fong-Yee%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
• Financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Rick%20Nolte
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Rick%20Nolte%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's financial summary
• What's the financial outcome of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jeline%20Manibo?
• How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jeline%20Manibo%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate monthly?
• What's the financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yunzhao%20Chen?
• How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yunzhao%20Chen%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
• How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Musharraf%20Hossain generate?
• What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Musharraf%20Hossain%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Konstantin%20Horas gross monthly?
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Konstantin%20Horas%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Colin%20Dunstan
• https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Colin%20Dunstan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
• Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Hong%20Zhou
• Financial intake of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Hong%20Zhou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
• How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Markus%20J%20Seibel make?
• How much profit is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Markus%20J%20Seibel%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en making per month?
• How much does http://creativecommons.org/licenses/by/4.0/ bring in each month?
• How much does https://s100.copyright.com/AppDispatchServlet?title=Loss%20of%20the%20vitamin%20D%20receptor%20in%20human%20breast%20and%20prostate%20cancers%20strongly%20induces%20cell%20apoptosis%20through%20downregulation%20of%20Wnt%2F%CE%B2-catenin%20signaling&author=Yu%20Zheng%20et%20al&contentID=10.1038%2Fboneres.2017.23©right=The%20Author%28s%29&publication=2095-6231&publicationDate=2017-09-05&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY gross monthly?
• Learn how profitable https://crossmark.crossref.org/dialog/?doi=10.1038/boneres.2017.23 is on a monthly basis
• How much income does https://citation-needed.springer.com/v2/references/10.1038/boneres.2017.23?format=refman&flavour=citation have?
• How much does https://doi.org/10.1007/s11033-025-10716-8 net monthly?
• Discover the revenue of https://doi.org/10.1186/s12885-023-10690-z
• Find out how much https://doi.org/10.1038/s41598-023-39626-0 earns monthly
• https://doi.org/10.1038/s41598-020-62182-w's financial summary
• Profit of https://www.protocols.io/
• Learn how profitable https://www.natureindex.com/ is on a monthly basis
• What is the earnings of http://www.naturechina.com?
• How much profit is https://www.natureasia.com/ja-jp making per month?

Analytics and Tracking {📊}

• Google Tag Manager

Libraries {📚}

• Prism.js
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• mxa-002c5801.gslb.pphosted.com
• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk