PMC . NCBI . NLM . NIH . GOV {
}
We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC2064700/.
Title:
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels - PMC
Description:
The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane mediates metabolic flow, Ca2+, and cell death signaling between the endoplasmic reticulum (ER) and mitochondrial networks. We demonstrate that VDAC1 is physically linked ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Title:
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels - PMC
Description:
The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane mediates metabolic flow, Ca2+, and cell death signaling between the endoplasmic reticulum (ER) and mitochondrial networks. We demonstrate that VDAC1 is physically linked ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Matching Content Categories {📚}
- Education
- Science
- Technology & Computing
Content Management System {📝}
What CMS is pmc.ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Pmc.ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of pmc.ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Pmc.ncbi.nlm.nih.gov Make Money? {💸}
The income method remains a mystery to us.
The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Pmc.ncbi.nlm.nih.gov might be cashing in, but we can't detect the method they're using.
Keywords {🔍}
mitochondrial, grp, pubmed, google, scholar, doi, protein, ipr, iprlbd, cells, vdac, effect, uptake, fig, cell, shown, pmc, mitochondria, article, cam, domain, free, proteins, omm, biol, control, fraction, membrane, mam, molecular, interaction, cac, complex, data, channel, expression, matrix, hela, reticulum, channels, rizzuto, controls, cytosolic, biochem, endoplasmic, stimulatory, release, interactions, previously, role,
Topics {✒️}
kidney lexa-ad–fused libraries org/cgi/content/full/jcb voltage-dependent anion-selective channel serca blocker tert-butyl-benzohydroquinone steady-state [ca2+]er level omm-ip3r-lbd224-605 /grp75cyt–expressing cells mortalin/grp75/peptide-binding protein 74 voltage-dependent anion channel marie-curie individual fellowship n-terminal repressor domain mrfp1-fused ip3r-lbd224-605 constructs ip3r-lbd224-605–expressing cells showed c-terminal domain reduced heat-shock protein pbp74 n-terminal akap1 domain histamine-/ip3-induced ca2+ release emilia-romagna programma regionale omm-ip3-lbd1-604-mrfp1 construct sds-page 2d separation omm-ip3r-lbd224-605–expressing cells sds-page protein separation omm-targeted ip3r-lbd domain full-length mouse ip3r-1 pmc copyright notice omm targeted n-terminal n-terminal cytosolic domain omm-targeted p130-ph domain af052659 tubulin-specific chaperone ca2+-phosphate precipitation technique grp75/mthsp70/pbp74/mortalin overexpression k508a omm-ip3r-lbd224-605 increased online supplemental material pmc beta search omm-ip3r-lbd224-605–cotransfected cells omm-ip3r-lbd224-605 cotransfected cells steady-state er [ca2+] steady-state [ca2+]er omm-ip3r-lbd224-605–transfected cells lethal interorganelle cross-talk steady [ca2+]er level ip3-induced ca2+ release ip3-insensitive ip3r-lbd224-605 isotype-specific monoclonal antibody ip3r ligand-binding domain er–mitochondrial interface outlined ip3r-lbd–induced augmentation mortalin/mthsp70/pbp74/grp75 preserve er–mitochondrial contacts er ca2+-handling machinery er-ip3r-lbd224-605-mrfp1
Questions {❓}
- An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?
- How is the newly identified regulatory activity on mitochondrial Ca2+ uptake exerted?
- Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood?
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