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Keywords {🔍}

cells, bak, activation, jurkat, cell, apoptosis, bzinduced, fig, doi, pubmed, google, scholar, levels, bax, noxa, jnk, death, mitochondrial, akt, signaling, mrllpr, mcl, apoptotic, proteins, blatt, treated, proapoptotic, pmc, activated, release, cytochrome, data, lymphocytes, article, protein, bcl, momp, increased, min, mice, kinase, line, mntbap, ffatpase, superoxide, signals, free, expression, results, membrane,

Topics {✒️}

ice-cold phosphate-buffered saline c-jun n-terminal kinase mitochondria intermembrane space propidium iodide jun n-terminal kinase mrl/mpj-faslpr apoptosis signal-regulating kinase1 reactive oxygen species cryptic n-terminal domain antiapoptotic phosphatidylinositol 3-kinase mouse embryonic fibroblasts mitogen-activated protein n-terminal specific antibodies sheep anti-mouse igg dharmacon rna technologies mitochondrial outer membrane map kinase cascade oligomycin-sensitivity-conferring protein component small molecule modulators oligomycin-sensitivity-conferring protein subunit pi3k-akt signaling axis antiapoptotic pi3k-akt signaling prosurvival pi3k-akt pathway jnk-selective kinase inhibitor phosphatidylinositol triphosphates results sirna knockdown cytosolic protein gapdh desired sirna cytosolic redox-sensor ask1 porphyrin benzodiazepine-induced superoxide signals bz-423-induced superoxide contributes superoxide dismutase mimics pan-caspase inhibitor zvad-fmk ice-cold pbs mrl-lpr mice results prosurvival kinase akt sds-polyacrylamide gel electrophoresis hsp90-akt phosphorylates ask1 redox-regulated transcription factors enliten rluciferase/luciferin reagent pmc beta search kinase cascade culminating phosphatidylinositol triphosphates water-soluble cationic metalloporphyrins reduces bz-423-induced o2∸ fas-mediated liver damage myrakt construct failed links bz-423-induced o2∸ proapoptotic mis proteins

Questions {❓}

• (2007) PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

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