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DOI . ORG {}

  1. Analyzed Page
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  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
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We began analyzing https://www.nature.com/articles/nchembio.551, but it redirected us to https://www.nature.com/articles/nchembio.551. The analysis below is for the second page.

Title[redir]:
Cholesterol modulates glycolipid conformation and receptor activity | Nature Chemical Biology
Description:
Experiments on reconstituted liposomes and sperm capacitation, an activation process involving the reduction in membrane cholesterol content and subsequent exposure of surface carbohydrate, show that cholesterol masks the presentation of glycolipid head groups by inducing a conformational shift in the glycan moiety. We document a new dimension of surface recognition in which communication is controlled through the collective behavior of lipids. Membrane cholesterol induces a tilt in glycolipid receptor headgroup, resulting in loss of access for ligand binding. This property appears to organize erythrocyte blood group presentation and glycolipid receptor function during the activation of sperm fertility, suggesting that lipid

Matching Content Categories {📚}

  • Education
  • Science
  • Animals & Wildlife

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

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Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


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Keywords {🔍}

article, google, scholar, cas, nature, lingwood, access, biol, membrane, content, cholesterol, cookies, biology, chem, grant, privacy, journal, receptor, clifford, cell, molecular, research, toronto, university, data, information, glycolipid, ilpo, vattulainen, simons, open, reprod, department, supplementary, function, advertising, subscribe, chemical, binnington, róg, kai, recognition, lipids, lipid, institution, buy, mol, nat, dev, authors,

Topics {✒️}

nature portfolio permissions reprints privacy policy research institute nature advertising social media author information authors single-molecule imaging kenichi author correspondence personal data data protection permissions springerlink instant access glycolipid receptor headgroup privacy molecular cell biology max planck institute bmbf format grant esf “lipidprod” grant competing financial interests membrane cholesterol induces glycolipid receptor function explore content subscription content european economic area institutional subscriptions read mpi-cbg stipend abnormal transmembrane signals autism spectrum disorder accepting optional cookies molecular life sciences journals search log ilpo vattulainen sperm recognition experiments cell plasma membranes kai simons molecular dynamics simulations membrane biology article lingwood manage preferences aalto university school communication published issue learn content receptor activity tomasz róg ünal coskun lingwood department communications article

Questions {❓}

  • Is cholesterol both the lock and key to abnormal transmembrane signals in Autism Spectrum Disorder?

Schema {🗺️}

WebPage:
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         headline:Cholesterol modulates glycolipid conformation and receptor activity
         description:Experiments on reconstituted liposomes and sperm capacitation, an activation process involving the reduction in membrane cholesterol content and subsequent exposure of surface carbohydrate, show that cholesterol masks the presentation of glycolipid head groups by inducing a conformational shift in the glycan moiety. We document a new dimension of surface recognition in which communication is controlled through the collective behavior of lipids. Membrane cholesterol induces a tilt in glycolipid receptor headgroup, resulting in loss of access for ligand binding. This property appears to organize erythrocyte blood group presentation and glycolipid receptor function during the activation of sperm fertility, suggesting that lipid 'allostery' is a means to regulate membrane recognition processes.
         datePublished:2011-04-03T00:00:00Z
         dateModified:2011-04-03T00:00:00Z
         pageStart:260
         pageEnd:262
         sameAs:https://doi.org/10.1038/nchembio.551
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            Membrane biophysics
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            Chemistry/Food Science
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            Bioorganic Chemistry
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      headline:Cholesterol modulates glycolipid conformation and receptor activity
      description:Experiments on reconstituted liposomes and sperm capacitation, an activation process involving the reduction in membrane cholesterol content and subsequent exposure of surface carbohydrate, show that cholesterol masks the presentation of glycolipid head groups by inducing a conformational shift in the glycan moiety. We document a new dimension of surface recognition in which communication is controlled through the collective behavior of lipids. Membrane cholesterol induces a tilt in glycolipid receptor headgroup, resulting in loss of access for ligand binding. This property appears to organize erythrocyte blood group presentation and glycolipid receptor function during the activation of sperm fertility, suggesting that lipid 'allostery' is a means to regulate membrane recognition processes.
      datePublished:2011-04-03T00:00:00Z
      dateModified:2011-04-03T00:00:00Z
      pageStart:260
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      sameAs:https://doi.org/10.1038/nchembio.551
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         Membrane biophysics
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         Biochemistry
         Cell Biology
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            address:
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            type:Organization
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      affiliation:
            name:Max Planck Institute for Molecular Cell Biology and Genetics
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      name:Division of Molecular Structure and Function, Research Institute, The Hospital for Sick Children, Toronto, Canada
      name:Department of Physics, Tampere University of Technology, Tampere, Finland
      name:Department of Physics, Tampere University of Technology, Tampere, Finland
      name:Department of Applied Physics, Aalto University School of Science and Technology, Espoo, Finland
      name:MEMPHYS-Centre for Biomembrane Physics, University of Southern Denmark, Odense, Denmark
      name:Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
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      name:Division of Molecular Structure and Function, Research Institute, The Hospital for Sick Children, Toronto, Canada
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External Links {🔗}(182)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

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  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

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  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
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CDN Services {📦}

  • Crossref

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