We are analyzing https://link.springer.com/article/10.1007/bf00731435.

Title:
Aglycone modulation of glycolipid receptor function | Glycoconjugate Journal
Description:
The aglycone has been largely ignored in consideration of glycoconjugate function. Evidence is reviewed which suggests that the role of the lipid in glycolipid carbohydrate function may be particularly significant. The lipid moiety can promote or reduce carbohydrate exposure of membrane glycolipids. Theoretical calculation has indicated that the plane of the plasma membrane can restrict the permitted conformations of a given glycolipid oligosaccharide. Thus the lipid moiety may influence the relative conformation of such carbohydrate sequences. Evidence of ceramide regulation of glycolipid function can be found in studies of enzyme substrate specificity, antiglycolipid recognition and bacterial/host cell interactions. Studies of verotoxin binding to its glycolipid receptor globotriaosyl ceramide indicate that modulation of receptor function by glycolipid fatty acid content plays an important role inin vitro binding assays, cell cytotoxicity and intracellular routing.
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Keywords {🔍}

google, scholar, lingwood, biol, chem, biochem, karmali, article, cell, glycolipid, karlsson, biophys, function, eds, sci, usa, infect, strömberg, proc, natl, acad, immun, biochemistry, content, lipid, eur, inrecent, advances, verocytotoxin, producing, coli, infections, goglio, amsterdam, elsevier, sciences, privacy, cookies, journal, rev, krivan, acta, res, ladisch, petric, boyd, publish, research, search, glycoconjugate,

Topics {✒️}

month download article/chapter bacterial/host cell interactions privacy choices/manage cookies verotoxin binding glycolipid carbohydrate function full article pdf reduce carbohydrate exposure glycolipid receptor function related subjects european economic area scope submit manuscript enzyme substrate specificity o-linked glycoconjugates glycolipid analogs o'brien ad journal finder publish lipid research 25 conditions privacy policy accepting optional cookies main content log neville dm jr aglycone modulation relative conformation lipid moiety structure cell biol a117 check access nyholm p instant access article lingwood krivan hc lingwood rights glycoconjugate function glycolipid function lindberg aa breakdown products carbohydrate sequences receptor function springer-verlag samuel je article log journal publish membrane glycolipids glycolipid oligosaccharide yiu sck ostroff sm scotland sm privacy policy personal data article cite lipid moiety

Schema {🗺️}

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         description:The aglycone has been largely ignored in consideration of glycoconjugate function. Evidence is reviewed which suggests that the role of the lipid in glycolipid carbohydrate function may be particularly significant. The lipid moiety can promote or reduce carbohydrate exposure of membrane glycolipids. Theoretical calculation has indicated that the plane of the plasma membrane can restrict the permitted conformations of a given glycolipid oligosaccharide. Thus the lipid moiety may influence the relative conformation of such carbohydrate sequences. Evidence of ceramide regulation of glycolipid function can be found in studies of enzyme substrate specificity, antiglycolipid recognition and bacterial/host cell interactions. Studies of verotoxin binding to its glycolipid receptor globotriaosyl ceramide indicate that modulation of receptor function by glycolipid fatty acid content plays an important role inin vitro binding assays, cell cytotoxicity and intracellular routing.
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            verotoxin binding
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      headline:Aglycone modulation of glycolipid receptor function
      description:The aglycone has been largely ignored in consideration of glycoconjugate function. Evidence is reviewed which suggests that the role of the lipid in glycolipid carbohydrate function may be particularly significant. The lipid moiety can promote or reduce carbohydrate exposure of membrane glycolipids. Theoretical calculation has indicated that the plane of the plasma membrane can restrict the permitted conformations of a given glycolipid oligosaccharide. Thus the lipid moiety may influence the relative conformation of such carbohydrate sequences. Evidence of ceramide regulation of glycolipid function can be found in studies of enzyme substrate specificity, antiglycolipid recognition and bacterial/host cell interactions. Studies of verotoxin binding to its glycolipid receptor globotriaosyl ceramide indicate that modulation of receptor function by glycolipid fatty acid content plays an important role inin vitro binding assays, cell cytotoxicity and intracellular routing.
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         Pathology
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