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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers
  13. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s12072-015-9656-7, but it redirected us to https://link.springer.com/article/10.1007/s12072-015-9656-7. The analysis below is for the second page.

Title[redir]:
Bile acids: emerging role in management of liver diseases | Hepatology International
Description:
Bile acids are well known for their effects on cholesterol homeostasis and lipid digestion. Since the discovery of bile acid receptors, of which there are farnesoid X receptor (FXR), a nuclear receptor, and the plasma membrane G-protein receptor, as well as Takeda G-protein coupled receptor clone 5, further roles have been elucidated for bile acids including glucose and lipid metabolism as well as inflammation. Additionally, treatment with bile acid receptor agonists has shown a decrease in the amount of atherosclerosis plaque formation and decreased portal vascular resistance and portal hypotension in animal models. Furthermore, rodent models have demonstrated antifibrotic activity using bile acid receptor agonists. Early human data using a FXR agonist, obeticholic acid, have shown promising results with improvement of histological activity and even a reduction of fibrosis. Human studies are ongoing and will provide further information on bile acid receptor agonist therapies. Thus, bile acids and their derivatives have the potential for management of liver diseases and potentially other disease states including diabetes and the metabolic syndrome.

Matching Content Categories {📚}

  • Education
  • Science
  • Environment

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {💸}

The income method remains a mystery to us.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Doi.org could be getting rich in stealth mode, or the way it's monetizing isn't detectable.

Keywords {🔍}

bile, pubmed, article, google, scholar, cas, acids, receptor, acid, central, nuclear, res, lipid, liver, fxr, metabolism, receptors, tgr, role, sanyal, disease, hofmann, privacy, cookies, content, research, kumar, farnesoid, glucose, regulation, signaling, function, data, information, publish, search, emerging, diseases, asgharpour, divya, metabolic, access, chapter, rev, biochem, chiang, pharmacol, intestinal, cell, usa,

Topics {✒️}

reporters/pages/interim-results-flint-clinical-trial divya kumar & arun sanyal protein-coupled receptor responsive month download article/chapter neuschwander-tetri ba nuclear hormone receptors bile acid-activated receptors nuclear receptors sxr/pxr divya kumar declares nuclear receptor fxr/bar bile acid receptors full article pdf hofmann af membrane-type receptor privacy choices/manage cookies emerging therapeutic target nuclear receptor pxr normal glucose homeostasis bunnett nw placebo-controlled trial orphan nuclear receptor multipurpose nuclear receptor bile acid solubility bile acid transporters author information authors bile acid signaling lithocholic acid sensor endogenous bile acids cholestatic bile acids bile acids recognition bile acid absorption shown promising results amon asgharpour declares bile salt biotransformations bile acid synthesis article asgharpour tgr5 receptor intestinal disease bile acid regulation european economic area dietschy jm kullak-ublick ga improves portal hypertension bristol myers-squibb neuro-humoral signaling nutrient signaling hormones conditions privacy policy hylemon pb article log demonstrated antifibrotic activity

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Bile acids: emerging role in management of liver diseases
         description:Bile acids are well known for their effects on cholesterol homeostasis and lipid digestion. Since the discovery of bile acid receptors, of which there are farnesoid X receptor (FXR), a nuclear receptor, and the plasma membrane G-protein receptor, as well as Takeda G-protein coupled receptor clone 5, further roles have been elucidated for bile acids including glucose and lipid metabolism as well as inflammation. Additionally, treatment with bile acid receptor agonists has shown a decrease in the amount of atherosclerosis plaque formation and decreased portal vascular resistance and portal hypotension in animal models. Furthermore, rodent models have demonstrated antifibrotic activity using bile acid receptor agonists. Early human data using a FXR agonist, obeticholic acid, have shown promising results with improvement of histological activity and even a reduction of fibrosis. Human studies are ongoing and will provide further information on bile acid receptor agonist therapies. Thus, bile acids and their derivatives have the potential for management of liver diseases and potentially other disease states including diabetes and the metabolic syndrome.
         datePublished:2015-08-29T00:00:00Z
         dateModified:2015-08-29T00:00:00Z
         pageStart:527
         pageEnd:533
         sameAs:https://doi.org/10.1007/s12072-015-9656-7
         keywords:
            Bile acids
            FXR
            TGR5
            Liver disease
            Hepatology
            Colorectal Surgery
            Surgery
         image:
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            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12072-015-9656-7/MediaObjects/12072_2015_9656_Fig2_HTML.gif
         isPartOf:
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                     address:
                        name:Virginia Commonwealth University, Richmond, USA
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ScholarlyArticle:
      headline:Bile acids: emerging role in management of liver diseases
      description:Bile acids are well known for their effects on cholesterol homeostasis and lipid digestion. Since the discovery of bile acid receptors, of which there are farnesoid X receptor (FXR), a nuclear receptor, and the plasma membrane G-protein receptor, as well as Takeda G-protein coupled receptor clone 5, further roles have been elucidated for bile acids including glucose and lipid metabolism as well as inflammation. Additionally, treatment with bile acid receptor agonists has shown a decrease in the amount of atherosclerosis plaque formation and decreased portal vascular resistance and portal hypotension in animal models. Furthermore, rodent models have demonstrated antifibrotic activity using bile acid receptor agonists. Early human data using a FXR agonist, obeticholic acid, have shown promising results with improvement of histological activity and even a reduction of fibrosis. Human studies are ongoing and will provide further information on bile acid receptor agonist therapies. Thus, bile acids and their derivatives have the potential for management of liver diseases and potentially other disease states including diabetes and the metabolic syndrome.
      datePublished:2015-08-29T00:00:00Z
      dateModified:2015-08-29T00:00:00Z
      pageStart:527
      pageEnd:533
      sameAs:https://doi.org/10.1007/s12072-015-9656-7
      keywords:
         Bile acids
         FXR
         TGR5
         Liver disease
         Hepatology
         Colorectal Surgery
         Surgery
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                     name:Virginia Commonwealth University, Richmond, USA
                     type:PostalAddress
                  type:Organization
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            name:Divya Kumar
            affiliation:
                  name:Virginia Commonwealth University
                  address:
                     name:Virginia Commonwealth University, Richmond, USA
                     type:PostalAddress
                  type:Organization
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            name:Arun Sanyal
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                     name:Virginia Commonwealth University, Richmond, USA
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               name:Virginia Commonwealth University, Richmond, USA
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External Links {🔗}(219)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.68s.