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  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
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We began analyzing https://link.springer.com/article/10.1007/s00401-016-1570-0, but it redirected us to https://link.springer.com/article/10.1007/s00401-016-1570-0. The analysis below is for the second page.

Title[redir]:
Brain imaging of neurovascular dysfunction in Alzheimer’s disease | Acta Neuropathologica
Description:
Neurovascular dysfunction, including blood–brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, are increasingly recognized to contribute to Alzheimer’s disease (AD). The spatial and temporal relationships between different pathophysiological events during preclinical stages of AD, including cerebrovascular dysfunction and pathology, amyloid and tau pathology, and brain structural and functional changes remain, however, still unclear. Recent advances in neuroimaging techniques, i.e., magnetic resonance imaging (MRI) and positron emission tomography (PET), offer new possibilities to understand how the human brain works in health and disease. This includes methods to detect subtle regional changes in the cerebrovascular system integrity. Here, we focus on the neurovascular imaging techniques to evaluate regional BBB permeability (dynamic contrast-enhanced MRI), regional CBF changes (arterial spin labeling- and functional-MRI), vascular pathology (structural MRI), and cerebral metabolism (PET) in the living human brain, and examine how they can inform about neurovascular dysfunction and vascular pathophysiology in dementia and AD. Altogether, these neuroimaging approaches will continue to elucidate the spatio-temporal progression of vascular and neurodegenerative processes in dementia and AD and how they relate to each other.

Matching Content Categories {šŸ“š}

  • Education
  • Health & Fitness
  • Science

Content Management System {šŸ“}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {šŸ“ˆ}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Doi.org Make Money? {šŸ’ø}

We find it hard to spot revenue streams.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Doi.org has a revenue plan, but it's either invisible or we haven't found it.

Keywords {šŸ”}

pubmed, scholar, google, article, alzheimers, cas, disease, central, imaging, brain, blood, flow, cerebral, mri, neurol, cognitive, impairment, functional, cereb, bloodbrain, barrier, mild, aging, neurosci, metab, zlokovic, neuroimaging, amyloid, magnetic, arterial, alzheimer, neurology, resonance, soc, memory, dois, int, sperling, neurovascular, dysfunction, fmri, hippocampal, study, usa, dynamic, vascular, ann, normal, med, dementia,

Topics {āœ’ļø}

month download article/chapter d-alanine2-d-leucine5-enkephalin depth-resolved optical imaging blood–brain barrier permeability blood–brain barrier breakdown blood-brain-barrier leakage amyloid β-peptide elimination including blood–brain barrier n-terminal amino acid blood–brain barrier dysfunction blood–brain barrier integrity positron emission tomography voxel-based morphometry studies guzmĆ”n-de-villoria ja blood–brain barrier link magnetic resonance imaging dynamic contrast-enhanced mri gadolinium-based contrast media av45-a07 study group predefined antero-temporal region av45-a05 study group imaging beta-amyloid pathology temporal beta-amyloid deposition full article pdf influence short-term decline hillman emc apoe ε4 interact year test–retest reliability case-control mri study [18f]fdg pet study age-related white matter multiple-time uptake data blood–brain barrier arterial spin labeling arterial spin labeling arterial spin-labeling brain blood flow functional mr imaging cerebral blood flow cortical blood flow villemagne vl common blood flow dynamic contrast-enhanced including cerebrovascular dysfunction shulman gl de leeuw f impaired cerebral autoregulation magn reson med functional brain imaging privacy choices/manage cookies

Questions {ā“}

  • Iadecola C (1993) Regulation of the cerebral microcirculation during neural activity: is nitric oxide the missing link?
  • Jagust W (2015) Is amyloid-β harmful to the brain?
  • Turner R (2002) How much cortex can a vein drain?

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         headline:Brain imaging of neurovascular dysfunction in Alzheimer’s disease
         description:Neurovascular dysfunction, including blood–brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, are increasingly recognized to contribute to Alzheimer’s disease (AD). The spatial and temporal relationships between different pathophysiological events during preclinical stages of AD, including cerebrovascular dysfunction and pathology, amyloid and tau pathology, and brain structural and functional changes remain, however, still unclear. Recent advances in neuroimaging techniques, i.e., magnetic resonance imaging (MRI) and positron emission tomography (PET), offer new possibilities to understand how the human brain works in health and disease. This includes methods to detect subtle regional changes in the cerebrovascular system integrity. Here, we focus on the neurovascular imaging techniques to evaluate regional BBB permeability (dynamic contrast-enhanced MRI), regional CBF changes (arterial spin labeling- and functional-MRI), vascular pathology (structural MRI), and cerebral metabolism (PET) in the living human brain, and examine how they can inform about neurovascular dysfunction and vascular pathophysiology in dementia and AD. Altogether, these neuroimaging approaches will continue to elucidate the spatio-temporal progression of vascular and neurodegenerative processes in dementia and AD and how they relate to each other.
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      description:Neurovascular dysfunction, including blood–brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, are increasingly recognized to contribute to Alzheimer’s disease (AD). The spatial and temporal relationships between different pathophysiological events during preclinical stages of AD, including cerebrovascular dysfunction and pathology, amyloid and tau pathology, and brain structural and functional changes remain, however, still unclear. Recent advances in neuroimaging techniques, i.e., magnetic resonance imaging (MRI) and positron emission tomography (PET), offer new possibilities to understand how the human brain works in health and disease. This includes methods to detect subtle regional changes in the cerebrovascular system integrity. Here, we focus on the neurovascular imaging techniques to evaluate regional BBB permeability (dynamic contrast-enhanced MRI), regional CBF changes (arterial spin labeling- and functional-MRI), vascular pathology (structural MRI), and cerebral metabolism (PET) in the living human brain, and examine how they can inform about neurovascular dysfunction and vascular pathophysiology in dementia and AD. Altogether, these neuroimaging approaches will continue to elucidate the spatio-temporal progression of vascular and neurodegenerative processes in dementia and AD and how they relate to each other.
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