Here's how DOI.ORG makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. External Links
  10. Analytics And Tracking
  11. Libraries
  12. Hosting Providers

We began analyzing https://link.springer.com/article/10.1007/s00395-017-0666-6, but it redirected us to https://link.springer.com/article/10.1007/s00395-017-0666-6. The analysis below is for the second page.

Title[redir]:
Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans | Basic Research in Cardiology
Description:
Genetic factors are known to modulate cardiac susceptibility to ventricular hypertrophy and failure. To determine how strain influences the transcriptional response to pressure overload-induced heart failure (HF) and which of these changes accurately reflect the human disease, we analyzed the myocardial transcriptional profile of mouse strains with high (C57BL/6J) and low (129S1/SvImJ) susceptibility for HF development, which we compared to that of human failing hearts. Following transverse aortic constriction (TAC), C57BL/6J mice developed overt HF while 129S1/SvImJ did not. Despite a milder aortic constriction, impairment of ejection fraction and ventricular remodeling (dilation, fibrosis) was more pronounced in C57BL/6J mice. Similarly, changes in myocardial gene expression were more robust in C57BL/6J (461 genes) compared to 129S1/SvImJ mice (71 genes). When comparing these patterns to human dilated cardiomyopathy (1344 genes), C57BL/6J mice tightly grouped to human hearts. Overlay and bioinformatic analysis of the transcriptional profiles of C57BL/6J mice and human failing hearts identified six co-regulated genes (POSTN, CTGF, FN1, LOX, NOX4, TGFB2) with established link to HF development. Pathway enrichment analysis identified angiotensin and IGF-1 signaling as most enriched putative upstream regulator and pathway, respectively, shared between TAC-induced HF in C57BL/6J mice and in human failing hearts. TAC-induced heart failure in C57BL/6J mice more closely reflects the gene expression pattern of human dilated cardiomyopathy compared to 129S1/SvImJ mice. Unbiased as well as targeted gene expression and pathway analyses identified periostin, angiotensin signaling, and IGF-1 signaling as potential causes of increased HF susceptibility in C57BL/6J mice and as potentially useful drug targets for HF treatment.

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Doi.org Make Money? {💸}

We can't tell how the site generates income.

Not all websites are made for profit; some exist to inform or educate users. Or any other reason why people make websites. And this might be the case. Doi.org might be earning cash quietly, but we haven't detected the monetization method.

Keywords {🔍}

pubmed, article, google, scholar, cas, heart, cardiac, mice, central, hypertrophy, failure, res, basic, gene, expression, cardiol, wang, supplementary, material, ventricular, cblj, httpsdoiorgs, pressure, circ, genetic, human, aortic, freiburg, xlsx, wende, bugger, mouse, cardiomyopathy, signaling, sci, chen, hypertension, research, myocardial, access, usa, left, factor, zhang, receptor, university, function, analysis, susceptibility, christoph,

Topics {✒️}

tak1-p38mapk/-jnk1/2 signaling pathway month download article/chapter apolipoprotein e-null mice angiotensin-converting enzyme gene myocyte renin–angiotensin system transverse aortic constriction ly-6chigh monocytes depend ras/p38 mapk/creb erk1/2/tgf-beta1 pathways pgc-1beta deficiency accelerates exercise-induced cardiac hypertrophy beta-adrenergic receptor stimulation mek–erk1/2 signalling pathway tac-induced heart failure cardiomyocyte tgf-beta signaling c57bl/6j genetic backgrounds gene expression analysis gene transcription tropomodulin-overexpressing transgenic mice article basic research inducible cardiomyocyte-specific deletion growth factor-1 attenuates renin–angiotensin system milder aortic constriction gene expression pattern targeted gene expression full article pdf myocardial gene expression small animal models angiotensin-converting enzyme el hajj mc related subjects isolated hypertrophic cardiomyopathy left ventricular hypertrophy cardiac pressure overload transcriptional profiles article koentges murine cardiac function privacy choices/manage cookies periostin expression reveals accelerated heart failure chronic heart failure congestive heart failure adverse cardiac remodelling lysyl oxidase inhibition left ventricular structure pressure overload hypertrophy blood periostin decrease american heart association aortic arch curvature

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans
         description:Genetic factors are known to modulate cardiac susceptibility to ventricular hypertrophy and failure. To determine how strain influences the transcriptional response to pressure overload-induced heart failure (HF) and which of these changes accurately reflect the human disease, we analyzed the myocardial transcriptional profile of mouse strains with high (C57BL/6J) and low (129S1/SvImJ) susceptibility for HF development, which we compared to that of human failing hearts. Following transverse aortic constriction (TAC), C57BL/6J mice developed overt HF while 129S1/SvImJ did not. Despite a milder aortic constriction, impairment of ejection fraction and ventricular remodeling (dilation, fibrosis) was more pronounced in C57BL/6J mice. Similarly, changes in myocardial gene expression were more robust in C57BL/6J (461 genes) compared to 129S1/SvImJ mice (71 genes). When comparing these patterns to human dilated cardiomyopathy (1344 genes), C57BL/6J mice tightly grouped to human hearts. Overlay and bioinformatic analysis of the transcriptional profiles of C57BL/6J mice and human failing hearts identified six co-regulated genes (POSTN, CTGF, FN1, LOX, NOX4, TGFB2) with established link to HF development. Pathway enrichment analysis identified angiotensin and IGF-1 signaling as most enriched putative upstream regulator and pathway, respectively, shared between TAC-induced HF in C57BL/6J mice and in human failing hearts. TAC-induced heart failure in C57BL/6J mice more closely reflects the gene expression pattern of human dilated cardiomyopathy compared to 129S1/SvImJ mice. Unbiased as well as targeted gene expression and pathway analyses identified periostin, angiotensin signaling, and IGF-1 signaling as potential causes of increased HF susceptibility in C57BL/6J mice and as potentially useful drug targets for HF treatment.
         datePublished:2017-12-29T00:00:00Z
         dateModified:2017-12-29T00:00:00Z
         pageStart:1
         pageEnd:17
         sameAs:https://doi.org/10.1007/s00395-017-0666-6
         keywords:
            Heart failure
            Transverse aortic constriction
            Gene expression
            Genetic background
            Cardiac function
            Cardiology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig6_HTML.gif
         isPartOf:
            name:Basic Research in Cardiology
            issn:
               1435-1803
               0300-8428
            volumeNumber:113
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Berlin Heidelberg
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Christoph Koentges
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mark E. Pepin
               affiliation:
                     name:University of Alabama at Birmingham
                     address:
                        name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Carolyn Müsse
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Katharina Pfeil
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sonia V. Viteri Alvarez
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Natalie Hoppe
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael M. Hoffmann
               affiliation:
                     name:University of Freiburg
                     address:
                        name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
                     name:University of Freiburg
                     address:
                        name:Institute for Clinical Chemistry and Laboratory Medicine, Medical Center, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Katja E. Odening
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
                     name:University of Freiburg
                     address:
                        name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Samuel Sossalla
               affiliation:
                     name:University Hospital Regensburg
                     address:
                        name:Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Andreas Zirlik
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
                     name:University of Freiburg
                     address:
                        name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Lutz Hein
               affiliation:
                     name:University of Freiburg
                     address:
                        name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
                     name:University of Freiburg
                     address:
                        name:Institute of Experimental and Clinical Pharmacology, BIOSS Center for Biological Signaling Studies, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Christoph Bode
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
                     name:University of Freiburg
                     address:
                        name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Adam R. Wende
               affiliation:
                     name:University of Alabama at Birmingham
                     address:
                        name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Heiko Bugger
               affiliation:
                     name:Freiburg University
                     address:
                        name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
                     name:University of Freiburg
                     address:
                        name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans
      description:Genetic factors are known to modulate cardiac susceptibility to ventricular hypertrophy and failure. To determine how strain influences the transcriptional response to pressure overload-induced heart failure (HF) and which of these changes accurately reflect the human disease, we analyzed the myocardial transcriptional profile of mouse strains with high (C57BL/6J) and low (129S1/SvImJ) susceptibility for HF development, which we compared to that of human failing hearts. Following transverse aortic constriction (TAC), C57BL/6J mice developed overt HF while 129S1/SvImJ did not. Despite a milder aortic constriction, impairment of ejection fraction and ventricular remodeling (dilation, fibrosis) was more pronounced in C57BL/6J mice. Similarly, changes in myocardial gene expression were more robust in C57BL/6J (461 genes) compared to 129S1/SvImJ mice (71 genes). When comparing these patterns to human dilated cardiomyopathy (1344 genes), C57BL/6J mice tightly grouped to human hearts. Overlay and bioinformatic analysis of the transcriptional profiles of C57BL/6J mice and human failing hearts identified six co-regulated genes (POSTN, CTGF, FN1, LOX, NOX4, TGFB2) with established link to HF development. Pathway enrichment analysis identified angiotensin and IGF-1 signaling as most enriched putative upstream regulator and pathway, respectively, shared between TAC-induced HF in C57BL/6J mice and in human failing hearts. TAC-induced heart failure in C57BL/6J mice more closely reflects the gene expression pattern of human dilated cardiomyopathy compared to 129S1/SvImJ mice. Unbiased as well as targeted gene expression and pathway analyses identified periostin, angiotensin signaling, and IGF-1 signaling as potential causes of increased HF susceptibility in C57BL/6J mice and as potentially useful drug targets for HF treatment.
      datePublished:2017-12-29T00:00:00Z
      dateModified:2017-12-29T00:00:00Z
      pageStart:1
      pageEnd:17
      sameAs:https://doi.org/10.1007/s00395-017-0666-6
      keywords:
         Heart failure
         Transverse aortic constriction
         Gene expression
         Genetic background
         Cardiac function
         Cardiology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00395-017-0666-6/MediaObjects/395_2017_666_Fig6_HTML.gif
      isPartOf:
         name:Basic Research in Cardiology
         issn:
            1435-1803
            0300-8428
         volumeNumber:113
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Christoph Koentges
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mark E. Pepin
            affiliation:
                  name:University of Alabama at Birmingham
                  address:
                     name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Carolyn Müsse
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Katharina Pfeil
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sonia V. Viteri Alvarez
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Natalie Hoppe
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael M. Hoffmann
            affiliation:
                  name:University of Freiburg
                  address:
                     name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
                  name:University of Freiburg
                  address:
                     name:Institute for Clinical Chemistry and Laboratory Medicine, Medical Center, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Katja E. Odening
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
                  name:University of Freiburg
                  address:
                     name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Samuel Sossalla
            affiliation:
                  name:University Hospital Regensburg
                  address:
                     name:Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Andreas Zirlik
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
                  name:University of Freiburg
                  address:
                     name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Lutz Hein
            affiliation:
                  name:University of Freiburg
                  address:
                     name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
                  name:University of Freiburg
                  address:
                     name:Institute of Experimental and Clinical Pharmacology, BIOSS Center for Biological Signaling Studies, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Christoph Bode
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
                  name:University of Freiburg
                  address:
                     name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Adam R. Wende
            affiliation:
                  name:University of Alabama at Birmingham
                  address:
                     name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Heiko Bugger
            affiliation:
                  name:Freiburg University
                  address:
                     name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
                  name:University of Freiburg
                  address:
                     name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Basic Research in Cardiology
      issn:
         1435-1803
         0300-8428
      volumeNumber:113
Organization:
      name:Springer Berlin Heidelberg
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:University of Alabama at Birmingham
      address:
         name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Institute for Clinical Chemistry and Laboratory Medicine, Medical Center, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:University Hospital Regensburg
      address:
         name:Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Institute of Experimental and Clinical Pharmacology, BIOSS Center for Biological Signaling Studies, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
         type:PostalAddress
      name:University of Alabama at Birmingham
      address:
         name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
         type:PostalAddress
      name:Freiburg University
      address:
         name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
         type:PostalAddress
      name:University of Freiburg
      address:
         name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Christoph Koentges
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Mark E. Pepin
      affiliation:
            name:University of Alabama at Birmingham
            address:
               name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
               type:PostalAddress
            type:Organization
      name:Carolyn Müsse
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Katharina Pfeil
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Sonia V. Viteri Alvarez
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Natalie Hoppe
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Michael M. Hoffmann
      affiliation:
            name:University of Freiburg
            address:
               name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
            name:University of Freiburg
            address:
               name:Institute for Clinical Chemistry and Laboratory Medicine, Medical Center, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Katja E. Odening
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
            name:University of Freiburg
            address:
               name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Samuel Sossalla
      affiliation:
            name:University Hospital Regensburg
            address:
               name:Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany
               type:PostalAddress
            type:Organization
      name:Andreas Zirlik
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
            name:University of Freiburg
            address:
               name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Lutz Hein
      affiliation:
            name:University of Freiburg
            address:
               name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
            name:University of Freiburg
            address:
               name:Institute of Experimental and Clinical Pharmacology, BIOSS Center for Biological Signaling Studies, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Christoph Bode
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
            name:University of Freiburg
            address:
               name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
      name:Adam R. Wende
      affiliation:
            name:University of Alabama at Birmingham
            address:
               name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Heiko Bugger
      affiliation:
            name:Freiburg University
            address:
               name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
               type:PostalAddress
            type:Organization
            name:University of Freiburg
            address:
               name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
      name:Institute for Clinical Chemistry and Laboratory Medicine, Medical Center, University of Freiburg, Freiburg, Germany
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
      name:Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
      name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
      name:Institute of Experimental and Clinical Pharmacology, BIOSS Center for Biological Signaling Studies, University of Freiburg, Freiburg, Germany
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
      name:Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, USA
      name:Cardiology and Angiology I, Heart Center, Freiburg University, Freiburg, Germany
      name:Faculty of Medicine, University of Freiburg, Freiburg, Germany
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(366)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com
4.77s.