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DOI . ORG {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. Hosting Providers
  14. CDN Services

We began analyzing https://link.springer.com/article/10.1007/s00277-023-05345-9, but it redirected us to https://link.springer.com/article/10.1007/s00277-023-05345-9. The analysis below is for the second page.

Title[redir]:
Waldenström macroglobulinemia: a review of pathogenesis, current treatment, and future prospects | Annals of Hematology
Description:
Waldenström macroglobulinemia (WM) is a chronic B-cell lymphoproliferative disorder characterized by lymphoplasmacytic cell overgrowth in the bone marrow and increased secretion of IgM immunoglobulins into the serum. Patients with WM have a variety of clinical outcomes, including long-term survival but inevitable recurrence. Recent advances in disease knowledge, including molecular and genetic principles with the discovery of MYD88 and CXCR4 mutations, have rapidly increased patient-tolerable treatment options. WM patients may benefit from chemotherapy regimens that include rituximab-based regimens, alkylating drugs, proteasome inhibitors, monoclonal antibodies, and drugs targeting Bruton tyrosine kinase inhibitors. In light of these advancements, patients can now receive treatment customized to their specific clinical characteristics, focusing on enhancing the depth and durability of their response while limiting the adverse effects. Despite the rapidly developing therapeutic armament against WM, a lack of high-quality evidence from extensive phase 3 trials remains a significant challenge in the research. We believe clinical outcomes will keep improving when new medicines are introduced while preserving efficacy and minimizing toxicity.

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Doi.org Make Money? {💸}

The income method remains a mystery to us.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Doi.org might be cashing in, but we can't detect the method they're using.

Keywords {🔍}

pubmed, article, google, scholar, macroglobulinemia, cas, waldenström, patients, clin, rituximab, treatment, central, oncol, waldenströms, blood, lymphoma, treon, phase, study, httpsdoiorgjco, writing, therapy, review, httpsdoiorgblood, waldenstroms, cancer, trial, methodology, original, draft, ghafoor, clinical, ibrutinib, usa, data, research, myd, waldenstrom, castillo, leuk, nature, httpsdoiorgs, springer, dimopoulos, transplantation, privacy, cookies, content, hameed, cell,

Topics {✒️}

month download article/chapter proteasome inhibitors autologous stem-cell transplantation accepted manuscript version proteasome inhibitor therapy received research funding alkylating drugs lymphoplasmacytic cell overgrowth maha hameed hafiza huda akhtar hassan min allah mohammad mohsin arshad include rituximab-based regimens hodgkin lymphoma full article pdf dimopoulos ma large population-based study including long-term survival kyle ra treon sp ghobrial im high-dose therapy lymphoplasmacytic lymphoma 1007/s00277-018-3311 cxcr4-mutated waldenström macroglobulinemia muhammad husnain privacy choices/manage cookies mantle-cell lymphomas chemotherapy regimens marginal zone lymphoma lymphoma working party springer international publishing cxcr4 antagonist ulocuplumab valley royal hospital population-based study shameera shaik masthan high-quality evidence immune-related factors article ghafoor castillo jj myd88 l265p mutation type ii cryoglobulinaemia faiz anwer article annals extended rituximab therapy check access additional information publisher instant access prospectively randomized trial phase ii study

Questions {❓}

  • Kristinsson SY, Landgren O (2011) What causes Waldenström’s macroglobulinemia: genetic or immune-related factors, or a combination?

Schema {🗺️}

WebPage:
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         headline:Waldenström macroglobulinemia: a review of pathogenesis, current treatment, and future prospects
         description:Waldenström macroglobulinemia (WM) is a chronic B-cell lymphoproliferative disorder characterized by lymphoplasmacytic cell overgrowth in the bone marrow and increased secretion of IgM immunoglobulins into the serum. Patients with WM have a variety of clinical outcomes, including long-term survival but inevitable recurrence. Recent advances in disease knowledge, including molecular and genetic principles with the discovery of MYD88 and CXCR4 mutations, have rapidly increased patient-tolerable treatment options. WM patients may benefit from chemotherapy regimens that include rituximab-based regimens, alkylating drugs, proteasome inhibitors, monoclonal antibodies, and drugs targeting Bruton tyrosine kinase inhibitors. In light of these advancements, patients can now receive treatment customized to their specific clinical characteristics, focusing on enhancing the depth and durability of their response while limiting the adverse effects. Despite the rapidly developing therapeutic armament against WM, a lack of high-quality evidence from extensive phase 3 trials remains a significant challenge in the research. We believe clinical outcomes will keep improving when new medicines are introduced while preserving efficacy and minimizing toxicity.
         datePublished:2023-07-06T00:00:00Z
         dateModified:2023-07-06T00:00:00Z
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      headline:Waldenström macroglobulinemia: a review of pathogenesis, current treatment, and future prospects
      description:Waldenström macroglobulinemia (WM) is a chronic B-cell lymphoproliferative disorder characterized by lymphoplasmacytic cell overgrowth in the bone marrow and increased secretion of IgM immunoglobulins into the serum. Patients with WM have a variety of clinical outcomes, including long-term survival but inevitable recurrence. Recent advances in disease knowledge, including molecular and genetic principles with the discovery of MYD88 and CXCR4 mutations, have rapidly increased patient-tolerable treatment options. WM patients may benefit from chemotherapy regimens that include rituximab-based regimens, alkylating drugs, proteasome inhibitors, monoclonal antibodies, and drugs targeting Bruton tyrosine kinase inhibitors. In light of these advancements, patients can now receive treatment customized to their specific clinical characteristics, focusing on enhancing the depth and durability of their response while limiting the adverse effects. Despite the rapidly developing therapeutic armament against WM, a lack of high-quality evidence from extensive phase 3 trials remains a significant challenge in the research. We believe clinical outcomes will keep improving when new medicines are introduced while preserving efficacy and minimizing toxicity.
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      dateModified:2023-07-06T00:00:00Z
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         Lymphoplasmacytic lymphoma
         Rituximab
         Alkylating agents
         Proteasome inhibitors
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         Oncology
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      name:Allama Iqbal Medical College, Lahore, Pakistan
      name:Department of Medicine and Endocrinology, Forth Valley Royal Hospital, Larbert, UK
      name:Multan Medical and Dental College, Multan, Pakistan
      name:Hamad Medical Corporation, Doha, Qatar
      name:Clements High School, Sugarland, USA
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      name:Taussig Cancer Center, Cleveland Clinic, Cleveland, USA
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External Links {🔗}(347)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
  • mx2.zoho.eu
  • mx3.zoho.eu

Name Servers:

  • josh.ns.cloudflare.com
  • zita.ns.cloudflare.com

CDN Services {📦}

  • Crossref

4.75s.