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We began analyzing https://link.springer.com/article/10.1007/s00248-010-9801-8, but it redirected us to https://link.springer.com/article/10.1007/s00248-010-9801-8. The analysis below is for the second page.

Title[redir]:
Intestinal Microbiota Was Assessed in Cirrhotic Patients with Hepatitis B Virus Infection | Microbial Ecology
Description:
To unravel the profile of intestinal microecological parameters in Chinese patients with asymptomatic carriage of hepatitis B virus (HBV), chronic hepatitis B, decompensated HBV cirrhosis, and health controls and to establish their correlation with liver disease progression, we performed quantitative PCR and immunological techniques to investigate fecal parameters, including population of fecal predominant bacteria and the abundance of some virulence genes derived from Escherichia coli, Bacteroides fragilis, Clostridium difficile, and Clostridium perfringens in fecal crude DNA and some immunological parameters in extracts of all fecal samples. Data analysis indicated that 16S rRNA gene copy numbers for Faecalibacterium prausnitzii, Enterococcus faecalis, Enterobacteriaceae, bifidobacteria, and lactic acid bacteria (Lactobacillus, Pediococcus, Leuconostoc, and Weissella) showed marked variation in the intestine of HBV cirrhotic patients. The Bifidobacteria/Enterobacteriaceae (B/E) ratio, which may indicate microbial colonization resistance of the bowel, was decreased significantly in turn from 1.15 ± 0.11 in healthy controls, 0.99 ± 0.09 in asymptomatic carriers, and 0.76 ± 0.08 in patients with chronic hepatitis B to 0.64 ± 0.09 in patients with decompensated HBV cirrhosis (for all, P < 0.01). This suggests that B/E ratio is useful for following the level of intestinal microecological disorder in the course of liver disease progression. The data for virulence gene abundance suggested increased diversity of virulence factors during liver disease progression. Fecal secretory IgA and tumor necrosis factor-α in decompensated HBV cirrhotic patients were present at higher levels than in other groups, which indicates that a complicated autoregulatory system tries to achieve a new intestinal microecological balance.

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Keywords {🔍}

article, google, scholar, pubmed, cas, patients, intestinal, liver, hepatitis, disease, fecal, microbiol, microbiota, bacteria, gastroenterol, cirrhotic, hbv, chronic, cirrhosis, genes, gut, bacterial, content, analysis, virulence, secretory, access, clin, privacy, cookies, data, research, microbial, quantitative, pcr, escherichia, coli, healthy, iga, infect, realtime, bile, publish, search, virus, infection, chen, health, progression, clostridium,

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lactic acid bacteria month download article/chapter yunbo chen & lanjuan li real-time pcr quantitation tumor necrosis factor-α short-chain galacto-oligosaccharides long-chain fructo-oligosaccharides tnf-alpha-induced increase aggregative-adherent escherichia coli small-subunit rrna genes real-time pcr secretory iga-mediated neutralization faecal bile acids full article pdf privacy choices/manage cookies chronic hiv infection escherichia coli strains mixed microbial populations performed quantitative pcr quantitative rt-pcr chronic hepatitis delta regulating inflammatory circuits chronic liver disease virulence-related genes decompensated hbv cirrhosis bile acids fecal crude dna fecal secretory immunoglobulin intestinal microecological disorder intestinal microecological balance peginterferon alpha-2b fecal predominant bacteria fecal secretory iga intestinal secretory iga investigate fecal parameters intestinal microecological parameters microbial colonization resistance intestinal barrier dysfunction european economic area showed marked variation mucosal immune response circulating secretory component identify postoperative recurrence bermudez-humaran lg selective gastrointestinal decontamination article lu virulence genes derived hbv cirrhotic patients developing liver cirrhosis segmented filamentous bacteria

Questions {❓}

Blum S, Schiffrin EJ (2003) Intestinal microflora and homeostasis of the mucosal immune response: implications for probiotic bacteria?

Schema {🗺️}

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         description:To unravel the profile of intestinal microecological parameters in Chinese patients with asymptomatic carriage of hepatitis B virus (HBV), chronic hepatitis B, decompensated HBV cirrhosis, and health controls and to establish their correlation with liver disease progression, we performed quantitative PCR and immunological techniques to investigate fecal parameters, including population of fecal predominant bacteria and the abundance of some virulence genes derived from Escherichia coli, Bacteroides fragilis, Clostridium difficile, and Clostridium perfringens in fecal crude DNA and some immunological parameters in extracts of all fecal samples. Data analysis indicated that 16S rRNA gene copy numbers for Faecalibacterium prausnitzii, Enterococcus faecalis, Enterobacteriaceae, bifidobacteria, and lactic acid bacteria (Lactobacillus, Pediococcus, Leuconostoc, and Weissella) showed marked variation in the intestine of HBV cirrhotic patients. The Bifidobacteria/Enterobacteriaceae (B/E) ratio, which may indicate microbial colonization resistance of the bowel, was decreased significantly in turn from 1.15 ± 0.11 in healthy controls, 0.99 ± 0.09 in asymptomatic carriers, and 0.76 ± 0.08 in patients with chronic hepatitis B to 0.64 ± 0.09 in patients with decompensated HBV cirrhosis (for all, P < 0.01). This suggests that B/E ratio is useful for following the level of intestinal microecological disorder in the course of liver disease progression. The data for virulence gene abundance suggested increased diversity of virulence factors during liver disease progression. Fecal secretory IgA and tumor necrosis factor-α in decompensated HBV cirrhotic patients were present at higher levels than in other groups, which indicates that a complicated autoregulatory system tries to achieve a new intestinal microecological balance.
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      description:To unravel the profile of intestinal microecological parameters in Chinese patients with asymptomatic carriage of hepatitis B virus (HBV), chronic hepatitis B, decompensated HBV cirrhosis, and health controls and to establish their correlation with liver disease progression, we performed quantitative PCR and immunological techniques to investigate fecal parameters, including population of fecal predominant bacteria and the abundance of some virulence genes derived from Escherichia coli, Bacteroides fragilis, Clostridium difficile, and Clostridium perfringens in fecal crude DNA and some immunological parameters in extracts of all fecal samples. Data analysis indicated that 16S rRNA gene copy numbers for Faecalibacterium prausnitzii, Enterococcus faecalis, Enterobacteriaceae, bifidobacteria, and lactic acid bacteria (Lactobacillus, Pediococcus, Leuconostoc, and Weissella) showed marked variation in the intestine of HBV cirrhotic patients. The Bifidobacteria/Enterobacteriaceae (B/E) ratio, which may indicate microbial colonization resistance of the bowel, was decreased significantly in turn from 1.15 ± 0.11 in healthy controls, 0.99 ± 0.09 in asymptomatic carriers, and 0.76 ± 0.08 in patients with chronic hepatitis B to 0.64 ± 0.09 in patients with decompensated HBV cirrhosis (for all, P < 0.01). This suggests that B/E ratio is useful for following the level of intestinal microecological disorder in the course of liver disease progression. The data for virulence gene abundance suggested increased diversity of virulence factors during liver disease progression. Fecal secretory IgA and tumor necrosis factor-α in decompensated HBV cirrhotic patients were present at higher levels than in other groups, which indicates that a complicated autoregulatory system tries to achieve a new intestinal microecological balance.
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