We are analyzing https://link.springer.com/article/10.1007/s003840050236.

Title:
Gut-liver axis | International Journal of Colorectal Disease
Description:
The gut and the liver are the key organs in nutrient absorption and metabolism. Bile acids, drugs, and toxins undergo extensive enterohepatic circulation. Bile acids play a major role in several hepatic and intestinal diseases. Endotoxins deriving from intestinal Gram-negative bacteria are important in the pathogenesis of liver and systemic diseases. Chronic liver diseases can influence gastrointestinal motility, which together with other factors may contribute to bacterial overgrowth and in patients with ascites to an increased risk of spontaneous bacterial peritonitis. Patients with end-stage liver disease frequently develop portal hypertension leading to varices, gastric vascular ectasia, and portal hypertensive gastroenteropathy. Several liver and biliary abnormalities are observed in patients with inflammatory bowel disease (primary sclerosing cholangitis, autoimmune hepatitis, cholelithiasis). The primary defect in hemochromatosis is located in the intestine, causing an inappropriate increase in iron absorption, and the liver is the site of earliest and heaviest iron deposition. Elevated transaminases are observed in many patients with celiac disease, and steatohepatitis frequently develops in patients with jejunoileal bypass and short bowel syndrome. Furthermore, the liver is the primary organ for metastasis of intestinal cancer. Many viral, bacterial, fungal, and parasitic diseases affect the intestine as well as the liver and the biliary tract.
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Keywords {🔍}

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Topics {✒️}

klinikum der johann-wolfgang-goethe-universität inflammatory bowel disease parasitic diseases affect biliary tract chronic liver diseases month download article/chapter gut-liver axis colorectal disease aims bile acids play primary sclerosing cholangitis intestinal gram-negative bacteria portal hypertensive gastroenteropathy influence gastrointestinal motility short bowel syndrome bile acids steatohepatitis frequently develops related subjects biliary abnormalities article international journal privacy choices/manage cookies intestinal diseases full article pdf systemic diseases celiac disease european economic area scope submit manuscript gastric vascular ectasia theodor-stern-kai 7 germany e-mail conditions privacy policy heaviest iron deposition journal finder publish accepting optional cookies spontaneous bacterial peritonitis primary defect primary organ check access instant access liver autoimmune hepatitis article zeuzem article log information privacy policy personal data books a journal publish article cite optional cookies manage preferences

Schema {🗺️}

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         description:The gut and the liver are the key organs in nutrient absorption and metabolism. Bile acids, drugs, and toxins undergo extensive enterohepatic circulation. Bile acids play a major role in several hepatic and intestinal diseases. Endotoxins deriving from intestinal Gram-negative bacteria are important in the pathogenesis of liver and systemic diseases. Chronic liver diseases can influence gastrointestinal motility, which together with other factors may contribute to bacterial overgrowth and in patients with ascites to an increased risk of spontaneous bacterial peritonitis. Patients with end-stage liver disease frequently develop portal hypertension leading to varices, gastric vascular ectasia, and portal hypertensive gastroenteropathy. Several liver and biliary abnormalities are observed in patients with inflammatory bowel disease (primary sclerosing cholangitis, autoimmune hepatitis, cholelithiasis). The primary defect in hemochromatosis is located in the intestine, causing an inappropriate increase in iron absorption, and the liver is the site of earliest and heaviest iron deposition. Elevated transaminases are observed in many patients with celiac disease, and steatohepatitis frequently develops in patients with jejunoileal bypass and short bowel syndrome. Furthermore, the liver is the primary organ for metastasis of intestinal cancer. Many viral, bacterial, fungal, and parasitic diseases affect the intestine as well as the liver and the biliary tract.
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         Portal system
         Inflammatory bowel disease
         Surgery
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         Hepatology
         Proctology
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