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google, scholar, cas, pubmed, vitamin, article, aarhus, greenlanders, ohd, hansen, med, pedersen, diet, denmark, greenland, university, levels, inuit, bone, int, clin, research, fare, danes, mosekilde, ethnicity, nuuk, traditional, deficiency, nutr, serum, dept, privacy, cookies, content, tissue, insufficiency, westernized, rejnmark, age, winter, study, calcium, metabolism, res, health, hospital, publish, search, international,

Topics {✒️}

calcium-ion-sensing cell-surface receptors month download article/chapter hanafin mf holick kline mf holick extracellular calcium-sensing receptor bone-specific alkaline phosphatase calcium-regulated pth release mulvad jc hansen inherent lower “set-point” deguchi jp middaugh rapid socio-cultural change kuhnlein dc muir vitamin d-binding protein 25-hydroxyvitamin d3-1alpha-hydroxylase full article pdf age-related intestinal resistance disorders affecting bone privacy choices/manage cookies coronary heart disease marine food-chain decreasing traditional food osteomalacic bone involvement intestinal calcium absorption traditional greenlandic food experimental clinical research fish products analysed true calcium absorption european economic area scope submit manuscript large mediterranean cohort charles ef eriksen boulay hv kuhnlein adult dene/metis gram ap hermann jul mb pederson northern infant syndrome nahm sw lee sonn lv avioli riccardi sc hebert long-term storage kumar bl riggs dionisi mt pacitti mazzaferro gs de jane hagelskjaer knudsen charlotte beck gylling efraim hans olsen serum parathyroid hormone healthy french adults ellen hansen foundation conditions privacy policy

Questions {❓}

• J Rungby L Mortensen K Jakobsen A Brock L Mosekilde (1993) Distribution of hydroxylated vitamin D metabolites [25OHD3 and 1,25(OH)2D3] in domestic pigs: evidence that 1,25(OH)2D3 is stored outside the blood circulation?
• JC Godel AG Hart (1984) Northern infant syndrome: a deficiency state?
• LB Rasmussen GL Hansen E Hansen B Koch L Mosekilde C Molgaard OH Sorensen L Ovesen (2000) Vitamin D: Should the supply in the Danish population be increased?
• RA Hegele TK Young PW Connelly (1997) Are Canadian Inuit at increased genetic risk for coronary heart disease?

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         headline:Vitamin D Insufficiency in Greenlanders on a Westernized Fare: Ethnic Differences in Calcitropic Hormones Between Greenlanders and Danes
         description:We studied the influence of age, gender, latitude, season, diet and ethnicity on plasma 25-hydroxyvitamin D 25 OHD, PTH, 1,25-dihydroxyvitamin D, vitamin D-binding protein, bone-specific alkaline phosphatase, and osteocalcin levels in 46 Greenlanders living in Nuuk (64°N) on a traditional fare (group A), 45 Greenlanders living in Nuuk on a westernized fare (group B), 54 Greenlanders (group C), and 43 Danes (Group D) living in Denmark (55°N) on a westernized fare. Blood specimens were drawn both summer and winter. Vitamin D insufficiency (plasma 25 OHD <40 nmol/l) was common in all four study groups during summer (23–74%) and winter (42–81%). Compared to groups A and D, vitamin D insufficiency was significantly more frequent in groups B and C. In all groups, summer levels of 25 OHD were above winter levels. Multiple regression analysis revealed a significant effect of ethnicity. Compared to Danes, Greenlanders had higher 1,25-dihydroxyvitamin D levels, but lower 25 OHD and PTH levels despite relatively low plasma calcium concentrations. In addition to ethnicity, 25(OH)D levels were influenced by age, season (summer > winter), and diet (a traditional Inuit diet>westernized diet). Ethnical differences exist between Greenlanders and Danes. Our results suggest that Greenlanders may have an inherent lower “set-point” for calcium-regulated PTH release or an enhanced renal 1,25(OH)2D production. In addition to ethnicity, age, season, and diet were important determinants of vitamin D status. Changes from a traditional to a westernized fare are associated with a reduced vitamin D status in Greenlanders. Vitamin D supplementation should be considered.
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      headline:Vitamin D Insufficiency in Greenlanders on a Westernized Fare: Ethnic Differences in Calcitropic Hormones Between Greenlanders and Danes
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            name:Aarhus Amtssygehus, Aarhus University Hospital, Aarhus
            address:
               name:Dept of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
               type:PostalAddress
            type:Organization
            name:Aarhus University, Aarhus
            address:
               name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Dept of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
      name:Dept of Medicine, Queen Ingrids Hospital, Nuuk, Greenland
      name:Steno Diabetes Centre, Gentofte, Denmark
      name:Dept of Medicine, Queen Ingrids Hospital, Nuuk, Greenland
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
      name:Center for Arctic Environmental Medicine, Dept of Environmental and Occupational Medicine, Aarhus University, Aarhus, Denmark
      name:Dept of Clinical Biochemistry, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
      name:Dept of Clinical Biochemistry, AKH, Aarhus University Hospital, Aarhus, Denmark
      name:Center for Primary Health Care, Nuuk, Greenland
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
      name:Dept of Medicine, Hospital of Holstebro, Holstebro, Denmark
      name:Dept of Endocrinology and Metabolism C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark
      name:Faculty of Health Sciences, Aarhus University, Aarhus, Denmark
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