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  1. Analyzed Page
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  6. Keywords
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We began analyzing https://link.springer.com/article/10.1007/BF02603118, but it redirected us to https://link.springer.com/article/10.1007/BF02603118. The analysis below is for the second page.

Title[redir]:
An evaluation of the molecular clock hypothesis using mammalian DNA sequences | Journal of Molecular Evolution
Description:
A statistical analysis of extensive DNA sequence data from primates, rodents, and artiodacytls clearly indicates that no global molecular clock exists in mammals. Rates of nucleotide subsitution in rodents are estimated to be four to eight times higher than those in higher primates and two to four times higher than those in artiodactyls. There is strong evidence for lower substitution rates in apes and humans than in monkeys, supporting the hominoid slowdown hypothesis. There is also evidence for lower rates in humans than in apes, suggesting a further rate slowdown in the human lineage after the separation of humans from apes. By contrast, substitution rates are nearly equal in mouse and rat. These results suggest that differences in generation time or, more precisely, in the number of germline DNA replications per year are the primary cause of rate differences in mammals. Further, these differences are more in line with the neutral mutation hypothesis than if the rates are the same for short-and long-living mammals.

Matching Content Categories {📚}

  • Education
  • Science
  • Animals & Wildlife

Content Management System {📝}

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Custom-built

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Traffic Estimate {📈}

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🌠 Phenomenal Traffic: 5M - 10M visitors per month


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Keywords {🔍}

google, scholar, article, cas, pubmed, evolution, gene, molecular, sequence, nucleotide, human, mol, evol, dna, biol, genes, sequences, nature, cdna, usa, rates, mouse, sci, evolutionary, proc, natl, acad, clock, structure, globin, expression, analysis, rate, cell, res, goodman, evidence, substitution, hominoid, rat, cloning, biochem, chem, science, βglobin, press, slightom, aldolase, content, apes,

Topics {✒️}

k-atpase β-chain gene month download article/chapter human β-globin gene time-dependent effect late oligocene-early miocene goat β-globin locus k-atpase β-subunit chimpanzee α-globin mrnas hominoid slowdown hypothesis neutral theory muscle acetylcholine receptor γ subunit precursor generation time human α-globin dna molecular clock human ∈-globin gene full article pdf ��4 β-globin genes bovine globin locus fetal globin gene βγ-crystallin superfamily multiple gene conversions related subjects molecular clock hypothesis molecular clock runs fossil-based divergence dates neutral mutation hypothesis rate slowdown human cholecystokinin gene privacy choices/manage cookies early paromomyid primate primate dna sequences mitochondrial genes dna-dna hybridization immunological time scale alu-type repeats βa-globin genes placental cdna encoding schimenti jc evolutionarily related enzymes mammalian dna sequences insulin gene family article li rat interleukin-3 gene germline dna replications check access instant access mouse aldolase genes dna repair genes van santen vl

Schema {🗺️}

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         description:A statistical analysis of extensive DNA sequence data from primates, rodents, and artiodacytls clearly indicates that no global molecular clock exists in mammals. Rates of nucleotide subsitution in rodents are estimated to be four to eight times higher than those in higher primates and two to four times higher than those in artiodactyls. There is strong evidence for lower substitution rates in apes and humans than in monkeys, supporting the hominoid slowdown hypothesis. There is also evidence for lower rates in humans than in apes, suggesting a further rate slowdown in the human lineage after the separation of humans from apes. By contrast, substitution rates are nearly equal in mouse and rat. These results suggest that differences in generation time or, more precisely, in the number of germline DNA replications per year are the primary cause of rate differences in mammals. Further, these differences are more in line with the neutral mutation hypothesis than if the rates are the same for short-and long-living mammals.
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      headline:An evaluation of the molecular clock hypothesis using mammalian DNA sequences
      description:A statistical analysis of extensive DNA sequence data from primates, rodents, and artiodacytls clearly indicates that no global molecular clock exists in mammals. Rates of nucleotide subsitution in rodents are estimated to be four to eight times higher than those in higher primates and two to four times higher than those in artiodactyls. There is strong evidence for lower substitution rates in apes and humans than in monkeys, supporting the hominoid slowdown hypothesis. There is also evidence for lower rates in humans than in apes, suggesting a further rate slowdown in the human lineage after the separation of humans from apes. By contrast, substitution rates are nearly equal in mouse and rat. These results suggest that differences in generation time or, more precisely, in the number of germline DNA replications per year are the primary cause of rate differences in mammals. Further, these differences are more in line with the neutral mutation hypothesis than if the rates are the same for short-and long-living mammals.
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External Links {🔗}(347)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Clipboard.js
  • Prism.js

Emails and Hosting {✉️}

Mail Servers:

  • mx.zoho.eu
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Name Servers:

  • josh.ns.cloudflare.com
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CDN Services {📦}

  • Crossref

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