
NCBI . NLM . NIH . GOV {
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Title[redir]:
Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease - PMC
Description:
Cumulative exposure to estrogen (E) and progesterone (P) over the menstrual cycle significantly influences the risk of developing breast cancer. Despite the dogma that PR in the breast merely serves as a marker of an active estrogen receptor (ER), ...
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Keywords {🔍}
breast, doi, cancer, cells, expression, normal, pubmed, google, scholar, human, cell, genes, samples, pmc, mammary, article, risk, free, receptor, correlated, luminal, figure, gene, progesterone, erpr, tissue, estrogen, data, gland, correlation, cancers, tumors, proportion, sections, signature, proliferation, epithelial, development, supp, cycle, pathways, prognosis, receptors, expressed, highly, study, levels, res, hormone, distinct,
Topics {✒️}
biotinylated goat anti-rabbit pmc beta search distant metastasis-free survival streptavidin-conjugated fluorescent label full-term pregnancy arrayexpress accession e-tabm-828 high-risk group comprises long-term cancer risk stable house-keeping genes taqman low-density arrays illumina ht-12v3 array nuclear counter-stain dapi fluorescence-activated cell sorter selected house-keeping genes pre-invasive breast lesions paracrine fgf/tbx3 signaling steroid receptor-positive cells cell-specific transcriptional outcomes supplementary materials oncotarget-05-8651-s001 natural inter-individual variation aging c57bl/6j mice levels surge pre-ovulation biotinylated secondary antibody steroid receptor negative adult mammary glands affymetrix microarray datasets genorm algorithm implemented pre-computed values hormone replacement therapy natl cancer inst elongating mammary gland anti-cd10 conjugated adult mammary gland mouse mammary gland transcription start site stem cell regulation supplementary material figures anti-muc1 conjugated risk score calculated pre-invasive lesions increases proliferation independently cell compartments based tissue-specific transcription post-ovulatory secretion beta-alanine metabolism model-based analysis human mammary epithelia pairwise correlation coefficients transcription start sites invasive breast cancer
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