
NCBI . NLM . NIH . GOV {
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Title[redir]:
Poly(A)-binding proteins are required for diverse biological processes in metazoans - PMC
Description:
PABPs [poly(A)-binding proteins] bind to the poly(A) tail of eukaryotic mRNAs and are conserved in species ranging from yeast to human. The prototypical cytoplasmic member, PABP1, is a multifunctional RNA-binding protein with roles in global and ...
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Keywords {🔍}
doi, pabp, pubmed, google, scholar, mrna, pmc, protein, translation, article, free, dpabp, polyabinding, proteins, cytoplasmic, cell, biol, mrnas, function, pabps, elegans, polya, epabp, cells, role, pab, mrnaspecific, development, oocytes, translational, required, figure, epab, germline, functions, studies, laevis, binding, repression, rna, drosophila, molecular, embryonic, knockdown, regulation, pabpc, deadenylation, osk, early, defects,
Topics {✒️}
lymphoma-derived murine erythroleukaemia pabp c-terminal mental retardation protein nonsense-mediated mrna decay–mechanisms testis-specific pabp mental retardation nonsense-mediated decay pathway pabpc family proteins dfmr1-positive neuritic rnps nonsense-mediated mrna decay steady-state intracellular distributions mrna turnover/mrna-specific stability rna-recognition motifs pmc beta search attenuates ras-mapk signaling binding protein-interacting protein anti-proliferative protein tob sxl-unr corepressor complex cross-rescue experiments showed substrate mrna recognition murine epab mrna highly conserved pabc depletion/add-back experiments � depletion/add-back experiments antagonize cup-mediated repression domain-swap experiments showed post-transcriptional control mechanisms mirna-mediated gene silencing multifunctional rna-binding protein molecular multi-functionality suggests heterozygous pabp deletion mel cells increased mirna-mediated translational repression n-terminal rrms rna-binding proteins play rna-binding proteins tia-1 heterozygous pabp hypomorph elegans la-related protein pabp-mediated mechanism sirna-mediated dpabp knockdown regulating mrna-specific translation resembles pabpn [23 mrna-specific translational repression compound heterozygous deletions mrna-specific translation repression mediated pabp sequestration long-term memory [45] amyotrophic lateral sclerosis abnormally protruding vulva publisher site pdf
Questions {❓}
- Poly(A) binding proteins: are they all created equal?
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Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
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Libraries {📚}
- jQuery
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- Particles.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
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Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
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CDN Services {📦}
- Ncbi