
DOI . ORG {
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Title[redir]:
Localization, anchoring and translational control of oskar, gurken, bicoid and nanos mRNA during Drosophila oogenesis: Fly: Vol 3, No 1
Description:
mRNA localization, and translation that is regulated spatially and temporally, are key mechanisms in the execution of polarized developmental programs. For over two decades, the Drosophila oocyte h...
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Keywords {π}
taylor, francis, group, page, localization, journals, open, search, access, translational, mechanisms, register, fly, volume, issue, anchoring, journal, article, citations, date, review, control, oskar, gurken, bicoid, nanos, mrna, drosophila, oogenesis, reprints, pdf, translation, key, mrnas, research, information, solutions, skip, main, content, publish, login, add, cart, home, bioscience, list, issues, translationa, advanced,
Topics {βοΈ}
twitter page taylor open francis group receive personalised research journals books polarized developmental programs embryonic axis formation summarize recent insights govern rna localization precise translational regulation key determinant mrnas drosophila oocyte oogenesis encoded article https date register subcellular localization translational control key mechanisms register add cart home nanos mrna published online regulated spatially valuable model biochemical studies greatly contributed asymmetric distribution contact newsroom email sign taylor england & wales sw1p 1wg mechanisms governing search journal 4161/fly review mrnas mechanisms nanos skip anchoring translationa oskar gurken bicoid //doi org/10 window translation
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articleSection:Review
name:Localization, anchoring and translational control of oskar, gurken, bicoid and nanos mRNA during Drosophila oogenesis
headline:Localization, anchoring and translational control of oskar, gurken, bicoid and nanos mRNA during Drosophila oogenesis
abstract:mRNA localization, and translation that is regulated spatially and temporally, are key mechanisms in the execution of polarized developmental programs. For over two decades, the Drosophila oocyte has served as a valuable model to study these mechanisms. Genetic and biochemical studies in flies have greatly contributed to the identification and understanding of factors that govern RNA localization and translational control. Embryonic axis formation is mediated through the subcellular localization and precise translational regulation of four key determinant mRNAs during oogenesis encoded by oskar, bicoid, gurken and nanos. In this review we aim to summarize recent insights into the mechanisms governing the asymmetric distribution and translation of these mRNAs.
description:mRNA localization, and translation that is regulated spatially and temporally, are key mechanisms in the execution of polarized developmental programs. For over two decades, the Drosophila oocyte has served as a valuable model to study these mechanisms. Genetic and biochemical studies in flies have greatly contributed to the identification and understanding of factors that govern RNA localization and translational control. Embryonic axis formation is mediated through the subcellular localization and precise translational regulation of four key determinant mRNAs during oogenesis encoded by oskar, bicoid, gurken and nanos. In this review we aim to summarize recent insights into the mechanisms governing the asymmetric distribution and translation of these mRNAs.
author:
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name:Jan-Michael Kugler
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name:Paul Lasko
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datePublished:2009-02-15
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