
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Immunotherapy for Prostate Cancer: Lessons from Responses to Tumor-Associated Antigens - PMC
Description:
Prostate cancer (PCa) is the most common cancer in men and the second most common cause of cancer-related death in men. In recent years, novel therapeutic options for PCa have been developed and studied extensively in clinical trials. Sipuleucel-T ...
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π Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {π}
cancer, google, scholar, pubmed, prostate, doi, patients, pca, cells, tumor, responses, antigen, immunotherapy, psa, pmc, immune, article, free, phase, clinical, trial, vaccine, antigens, survival, nyeso, cell, muc, tcell, sipuleucelt, expression, treatment, pap, study, psma, trials, human, immunol, target, mcrpc, response, specific, protein, showed, ongoing, clin, vaccination, therapy, date, iii, levels,
Topics {βοΈ}
granulocyte-macrophage colony-stimulating factor pmsa-derived hla-a2-restricted peptide psa-specific t-cell responses pap-specific t-cell responses pre-existing anti-tumor responses hla-a2-restricted peptides poxviral-based psa-targeted immunotherapy prostate-specific membrane antigen prostate-specific membrane antigen psa-tricom/prostvac-vf vaccinations ptvg-hp dna vaccine infgamma-secreting lymphocytes specific vaccinia-based priming vector tartrate-resistant acid phosphatase t-cell-dependent mechanism mage-c2/ct10 protein expression improve t-cell reactivity cd8+ t-cell responses pmc beta search induced t-cell responses human prostate-specific antigen prostvac-vf/psa-tricom hla class i-a11 high-grade intraepithelial neoplasia hormone-refractory prostate carcinoma hla-a2-presented peptides t-cell monitoring studies vector-based peptide vaccines poxviral-based psa vaccine block t-cell activation amplify t-cell activation blocking t-cell activation pre-existing ctl responses significant t-cell responses genetically engineered t-cells hormone-refractory prostate cancer nuclear factor-ΞΊb pathways recombinant ny-eso-1 protein heat-shock protein grp170 ny-eso-1 expressing malignities myeloid-derived suppressor cells transfected monocyte-derived dcs selecting patient-specific mutations castration-resistant prostate cancer steroidal anti-inflammatory drugs a-kinase anchor proteins prostate tumor-bearing mice induced ny-eso-1 specific cytotoxic t-cells responses pap-based dna vaccine
Questions {β}
- A polyvalent vaccine for high-risk prostate patients: βare more antigens better?
- Does PSA play a role as a promoting agent during the initiation and/or progression of prostate cancer?
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- Income figures for https://scholar.google.com/scholar_lookup?journal=Cancer%20Immunol%20Immunother&title=A%20polyvalent%20vaccine%20for%20high-risk%20prostate%20patients:%20%E2%80%9Care%20more%20antigens%20better?%E2%80%9D&author=SF%20Slovin&author=G%20Ragupathi&author=C%20Fernandez&author=M%20Diani&author=MP%20Jefferson&volume=56&issue=12&publication_year=2007&pages=1921-30&pmid=17619878&doi=10.1007/s00262-007-0335-y&
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- https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=Abstract%20A16:%20a%20phase%20I/II%20clinical%20trial%20of%20a%20MUC1-glycopeptide%20dendritic%20cell%20vaccine%20in%20castrate%20resistant%20non-metastatic%20prostate%20cancer%20patients&author=P%20Major&author=L%20Lacombe&author=Y%20Fradet&author=R%20Foley&author=E%20Scheid&volume=72&issue=4%20Suppl&publication_year=2012&pages=A16&doi=10.1158/1538-7445.PRCA2012-A16&'s revenue stream
- Earnings of https://doi.org/10.1038/nrc1669
- Revenue of https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Cancer&title=Cancer/testis%20antigens,%20gametogenesis%20and%20cancer&author=AJ%20Simpson&author=OL%20Caballero&author=A%20Jungbluth&author=YT%20Chen&author=LJ%20Old&volume=5&issue=8&publication_year=2005&pages=615-25&pmid=16034368&doi=10.1038/nrc1669&
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- Income figures for https://doi.org/10.1002/pros.20025
- Learn about the earnings of https://scholar.google.com/scholar_lookup?journal=Prostate&title=NY-ESO-1%20protein%20expression%20and%20humoral%20immune%20responses%20in%20prostate%20cancer&author=A%20Foss%C3%A5&author=A%20Berner&author=SD%20Foss%C3%A5&author=E%20Hernes&author=G%20Gaudernack&volume=59&issue=4&publication_year=2004&pages=440-7&pmid=15065093&doi=10.1002/pros.20025&
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- How much does https://scholar.google.com/scholar_lookup?journal=Prostate&title=Immunohistochemical%20expression%20of%20tumor%20antigens%20MAGE-A1,%20MAGE-A3/4,%20and%20NY-ESO-1%20in%20cancerous%20and%20benign%20prostatic%20tissue&author=T%20Hudolin&author=A%20Juretic&author=GC%20Spagnoli&author=J%20Pasini&author=D%20Bandic&volume=66&issue=1&publication_year=2006&pages=13-8&pmid=16114059&doi=10.1002/pros.20312& pull in monthly?
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- What are the total earnings of https://scholar.google.com/scholar_lookup?journal=Cancer%20Sci&title=Cancer/testis%20(CT)%20antigens:%20potential%20targets%20for%20immunotherapy&author=OL%20Caballero&author=YT%20Chen&volume=100&issue=11&publication_year=2009&pages=2014-21&pmid=19719775&doi=10.1111/j.1349-7006.2009.01303.x&?
- Get to know https://doi.org/10.1073/pnas.041625098's earnings
- How much does https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&title=Identification%20of%20proacrosin%20binding%20protein%20sp32%20precursor%20as%20a%20human%20cancer/testis%20antigen&author=T%20Ono&author=T%20Kurashige&author=N%20Harada&author=Y%20Noguchi&author=T%20Saika&volume=98&issue=6&publication_year=2001&pages=3282-7&pmid=11248070&doi=10.1073/pnas.041625098& net monthly?
- What's the monthly money flow for https://doi.org/10.1073/pnas.95.9.5211?
- Revenue of https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&title=Identification%20of%20a%20meiosis-specific%20protein%20as%20a%20member%20of%20the%20class%20of%20cancer/testis%20antigens&author=O%20T%C3%BCreci&author=U%20Sahin&author=C%20Zwick&author=M%20Koslowski&author=G%20Seitz&volume=95&issue=9&publication_year=1998&pages=5211-6&pmid=9560255&doi=10.1073/pnas.95.9.5211&
- How much profit does https://doi.org/10.1073/pnas.061507398 generate?
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&title=CD4(+)%20T%20cell%20recognition%20of%20MHC%20class%20II-restricted%20epitopes%20from%20NY-ESO-1%20presented%20by%20a%20prevalent%20HLA%20DP4%20allele:%20association%20with%20NY-ESO-1%20antibody%20production&author=G%20Zeng&author=X%20Wang&author=PF%20Robbins&author=SA%20Rosenberg&author=RF%20Wang&volume=98&issue=7&publication_year=2001&pages=3964-9&pmid=11259659&doi=10.1073/pnas.061507398&?
- How much money does https://scholar.google.com/scholar_lookup?journal=Tunis%20Med&title=NY-ESO-1%20expression%20and%20immunogenicity%20in%20prostate%20cancer%20patients&author=A%20Gati&author=N%20Lajmi&author=A%20Derouiche&author=R%20Marrakchi&author=M%20Chebil&volume=89&issue=10&publication_year=2011&pages=779-83&pmid=22076902& make?
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- https://doi.org/10.1158/0008-5472.CAN-08-3529's financial summary
- How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=Potentiating%20endogenous%20antitumor%20immunity%20to%20prostate%20cancer%20through%20combination%20immunotherapy%20with%20CTLA4%20blockade%20and%20GM-CSF&author=L%20Fong&author=SS%20Kwek&author=S%20O%E2%80%99Brien&author=B%20Kavanagh&author=DG%20McNeel&volume=69&issue=2&publication_year=2009&pages=609-15&pmid=19147575&doi=10.1158/0008-5472.CAN-08-3529& rake in every month?
- https://doi.org/10.4049/jimmunol.165.2.1153's financial summary
- How much does https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=Identification%20of%20CD4+%20T%20cell%20epitopes%20from%20NY-ESO-1%20presented%20by%20HLA-DR%20molecules&author=G%20Zeng&author=CE%20Touloukian&author=X%20Wang&author=NP%20Restifo&author=SA%20Rosenberg&volume=165&issue=2&publication_year=2000&pages=1153-9&pmid=10878395&doi=10.4049/jimmunol.165.2.1153& pull in monthly?
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- How much money does https://doi.org/10.1371/journal.pone.0021366 make?
- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=PLoS%20One&title=MAGE-C2/CT10%20protein%20expression%20is%20an%20independent%20predictor%20of%20recurrence%20in%20prostate%20cancer&author=L%20von%20Boehmer&author=L%20Keller&author=A%20Mortezavi&author=M%20Provenzano&author=G%20Sais&volume=6&issue=7&publication_year=2011&pages=e21366&pmid=21754986&doi=10.1371/journal.pone.0021366&?
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- How profitable is https://doi.org/10.1002/pros.2990210202?
- Monthly income for https://scholar.google.com/scholar_lookup?journal=Prostate&title=Presence%20of%20calcitonin-like%20immunoreactivity%20(iCT)%20in%20human%20prostate%20gland:%20evidence%20for%20iCT%20secretion%20by%20cultured%20prostate%20cells&author=GV%20Shah&author=MJ%20Noble&author=M%20Austenfeld&author=J%20Weigel&author=LJ%20Deftos&volume=21&issue=2&publication_year=1992&pages=87-97&pmid=1409122&doi=10.1002/pros.2990210202&
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- https://doi.org/10.1002/1097-0215(20010101)91:1<46::AID-IJC1008>3.0.CO;2-0's total income per month
- How profitable is https://scholar.google.com/scholar_lookup?journal=Int%20J%20Cancer&title=Role%20of%20stimulatory%20guanine%20nucleotide%20binding%20protein%20(GSalpha)%20in%20proliferation%20of%20PC-3M%20prostate%20cancer%20cells&author=J%20Chien&author=GV%20Shah&volume=91&issue=1&publication_year=2001&pages=46-54&pmid=11149419&doi=10.1002/1097-0215(20010101)91:1<46::AID-IJC1008>3.0.CO;2-0&?
- How much does https://doi.org/10.1002/ijc.21158 earn?
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Int%20J%20Cancer&title=Calcitonin%20increases%20invasiveness%20of%20prostate%20cancer%20cells:%20role%20for%20cyclic%20AMP-dependent%20protein%20kinase%20A%20in%20calcitonin%20action&author=VS%20Sabbisetti&author=S%20Chirugupati&author=S%20Thomas&author=KS%20Vaidya&author=D%20Reardon&volume=117&issue=4&publication_year=2005&pages=551-60&pmid=15929083&doi=10.1002/ijc.21158&?
- How much income does https://doi.org/10.1111/j.1365-2141.2007.06940.x have?
- Get to know https://scholar.google.com/scholar_lookup?journal=Br%20J%20Haematol&title=AKAP-4:%20a%20novel%20cancer%20testis%20antigen%20for%20multiple%20myeloma&author=M%20Chiriva-Internati&author=R%20Ferrari&author=Y%20Yu&author=C%20Hamrick&author=N%20Gagliano&volume=140&issue=4&publication_year=2008&pages=465-8&pmid=18217892&doi=10.1111/j.1365-2141.2007.06940.x&'s earnings
- How much income does https://doi.org/10.1002/pros.21400 have?
- https://scholar.google.com/scholar_lookup?journal=Prostate&title=Identification%20of%20AKAP-4%20as%20a%20new%20cancer/testis%20antigen%20for%20detection%20and%20immunotherapy%20of%20prostate%20cancer&author=M%20Chiriva-Internati&author=Y%20Yu&author=L%20Mirandola&author=N%20D%E2%80%99Cunha&author=F%20Hardwicke&volume=72&issue=1&publication_year=2012&pages=12-23&pmid=21520158&doi=10.1002/pros.21400& income
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- Income figures for https://scholar.google.com/scholar_lookup?journal=Urology&title=Plasma%20levels%20of%20interleukin-6%20and%20its%20soluble%20receptor%20are%20associated%20with%20prostate%20cancer%20progression%20and%20metastasis&author=SF%20Shariat&author=B%20Andrews&author=MW%20Kattan&author=J%20Kim&author=TM%20Wheeler&volume=58&issue=6&publication_year=2001&pages=1008-15&pmid=11744478&doi=10.1016/S0090-4295(01)01405-4&
- https://doi.org/10.1158/1078-0432.CCR-06-2937 income
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Clin%20Cancer%20Res&title=Granulocyte%20macrophage%20colony-stimulating%20factor%20%E2%80%93%20secreting%20allogeneic%20cellular%20immunotherapy%20for%20hormone-refractory%20prostate%20cancer&author=EJ%20Small&author=N%20Sacks&author=J%20Nemunaitis&author=WJ%20Urba&author=E%20Dula&volume=13&issue=13&publication_year=2007&pages=3883-91&pmid=17606721&doi=10.1158/1078-0432.CCR-06-2937&
- How much revenue does https://doi.org/10.1002/cncr.23669 generate?
- What's the financial intake of https://scholar.google.com/scholar_lookup?journal=Cancer&title=Phase%201/2%20dose-escalation%20study%20of%20a%20GM-CSF-secreting,%20allogeneic,%20cellular%20immunotherapy%20for%20metastatic%20hormone-refractory%20prostate%20cancer&author=CS%20Higano&author=JM%20Corman&author=DC%20Smith&author=AS%20Centeno&author=CP%20Steidle&volume=113&issue=5&publication_year=2008&pages=975-84&pmid=18646045&doi=10.1002/cncr.23669&?
- How much money does https://scholar.google.com/scholar_lookup?title=A%20Phase%20III%20Trial%20of%20GVAX%20Immunotherapy%20for%20Prostate%20Cancer%20Versus%20Docetaxel%20Plus%20Prednisone%20in%20Asymptomatic,%20Castration-Resistant%20Prostate%20Cancer%20(CRPC)&author=C%20Higano&author=B%20Somer&author=B%20Curti&author=D%20Petrylak&author=CG%20Drake&publication_year=2009& make?
- https://scholar.google.com/scholar_lookup?title=A%20Phase%20III%20trial%20of%20GVAX%20Immunotherapy%20for%20Prostate%20Cancer%20in%20Combination%20with%20Docetaxel%20Versus%20Docetaxel%20Plus%20Prednisone%20in%20Symptomatic,%20Castration-Resistant%20Prostate%20Cancer%20(CRPC)&author=E%20Small&author=T%20Demkow&author=WR%20Gerritsen&author=F%20Rolland&author=P%20Hoskin&publication_year=2009&'s total income per month
- https://doi.org/10.1016/S1470-2045(12)70007-4's total income per month
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- Profit of https://doi.org/10.1007/s00262-012-1330-5
- How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Immunol%20Immunother&title=T%20cell%20profiling%20reveals%20high%20CD4+CTLA-4%20+%20T%20cell%20frequency%20as%20dominant%20predictor%20for%20survival%20after%20prostate%20GVAX/ipilimumab%20treatment&author=SJ%20Santegoets&author=AG%20Stam&author=SM%20Lougheed&author=H%20Gall&author=PE%20Scholten&volume=62&issue=2&publication_year=2013&pages=245-56&pmid=22878899&doi=10.1007/s00262-012-1330-5& pull in monthly?
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- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Cancer%20Immunol%20Immunother&title=Immuno-gene%20therapy%20of%20cancer%20with%20tumour-mRNA%20transfected%20dendritic%20cells&author=JA%20Kyte&author=G%20Gaudernack&volume=55&issue=11&publication_year=2006&pages=1432-42&pmid=16612595&doi=10.1007/s00262-006-0161-7&?
- How much money does https://doi.org/10.1038/sj.bjc.6602761 generate?
- What's the profit of https://scholar.google.com/scholar_lookup?journal=Br%20J%20Cancer&title=Immunotherapy%20with%20allotumour%20mRNA-transfected%20dendritic%20cells%20in%20androgen-resistant%20prostate%20cancer%20patients&author=LJ%20Mu&author=JA%20Kyte&author=G%20Kvalheim&author=S%20Aamdal&author=S%20Dueland&volume=93&issue=7&publication_year=2005&pages=749-56&pmid=16136047&doi=10.1038/sj.bjc.6602761&?
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- Check the income stats for https://scholar.google.com/scholar_lookup?journal=J%20Transl%20Med&title=Cancer%20immunotherapy:%20avoiding%20the%20road%20to%20perdition&author=M%20Chiriva-Internati&author=F%20Grizzi&author=RK%20Bright&author=W%20Martin%20Kast&volume=2&issue=1&publication_year=2004&pages=26&pmid=15283862&doi=10.1186/1479-5876-2-26&
- What are the earnings of https://doi.org/10.1186/1479-5876-9-214?
- How much does https://scholar.google.com/scholar_lookup?journal=J%20Transl%20Med&title=Defining%20the%20critical%20hurdles%20in%20cancer%20immunotherapy&author=BA%20Fox&author=DJ%20Schendel&author=LH%20Butterfield&author=S%20Aamdal&author=JP%20Allison&volume=9&issue=1&publication_year=2011&pages=214&pmid=22168571&doi=10.1186/1479-5876-9-214& make?
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- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Cancer%20J&title=Gene%20signature%20in%20melanoma%20associated%20with%20clinical%20activity:%20a%20potential%20clue%20to%20unlock%20cancer%20immunotherapy&author=TF%20Gajewski&author=J%20Louahed&author=VG%20Brichard&volume=16&issue=4&publication_year=2010&pages=399-403&pmid=20693853&doi=10.1097/PPO.0b013e3181eacbd8&?
- https://doi.org/10.1093/annonc/mds263's financial summary
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