NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3422012/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC3422012/. The analysis below is for the second page.
Title[redir]:
A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development - PMC
Description:
The binding of the eukaryotic initiation factor 4E (eIF4E) to the mRNA 5′ cap structure is a rate-limiting step in mRNA translation initiation. eIF4E promotes ribosome recruitment to the mRNA. In Drosophila, the eIF4E homologous protein (d4EHP) ...
Title[redir]:
A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development - PMC
Description:
The binding of the eukaryotic initiation factor 4E (eIF4E) to the mRNA 5′ cap structure is a rate-limiting step in mRNA translation initiation. eIF4E promotes ribosome recruitment to the mRNA. In Drosophila, the eIF4E homologous protein (d4EHP) ...
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Custom-built
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Traffic Estimate {📈}
What is the average monthly size of ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 6,694,437 visitors per month in the current month.
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Keywords {🔍}
gigyf, mehp, ehp, protein, fig, eife, doi, pubmed, google, scholar, proteins, binding, translation, cells, mice, pmc, cell, mrna, article, free, analysis, complex, gene, cap, interaction, hela, biol, initiation, drosophila, mycgigyf, control, identified, motif, mol, mammalian, development, buffer, factor, dehp, haehp, immunoblotting, embryonic, znf, mehpgigyf, antibodies, mouse, beads, mass, eukaryotic, structure,
Topics {✒️}
cytomegalovirus promoter-induced cre-transgenic horseradish peroxidase-conjugated anti-mouse anti-flag m2-agarose beads eukaryotic initiation factor-4e flag-hmk-4ehp recombinant protein sequence-specific rna-binding proteins hash wudqwa9ufcvm/3atj9vv5xjeagz6hgs7zqcr97qk3f+zq1cdxf9zm2vto4h9wy6cthxu9yyrda+ pmc beta search keratin-free sds-page myc-gigyf2-mut expression vectors high-confidence interacting partners bicoid-related d4ehp-binding motif considered high-confidence interactors 32p-labeled recombinant 4ehp high-confidence interaction partners conserved beta-hairpin recognition simplified cap-analog resin [35s]methionine metabolic labeling [35s]protein labeling mix c57bl/6j female mice bio-rad protein assay m7gdp-agarose beads prepared wild-type/mutant myc-gigyf2 canonical eif4e-binding motif cap-dependent translation initiation m7gdp-coupled agarose beads anti-rabbit secondary antibodies reciprocal ap-ms experiment sirna-treated hela cells rna-binding protein complex methionine-free media performing triple-transfection experiments eukaryotic translation initiation mammalian eif4e-family members m4ehp-binding site mutant post-transcriptional gene expression indirect rna-dependent interactions [35s]methionine incorporation normalized [35s]methionine incorporation compared flag-hmk-4ehp plasmids rna-binding proteins play eif4e-binding protein 4e supplementary materials included bicoid d4ehp-binding motif 50% protein g-sepharose mtorc1-mediated cell proliferation striatin-interacting phosphatase identify m4ehp-interacting proteins hela s3 cells m4ehp-gigyf2 complex functions
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