
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Exploring the full spectrum of macrophage activation - PMC
Description:
Macrophages display remarkable plasticity and can change their physiology in response to environmental cues. These changes can give rise to different populations of cells with distinct functions. In this Review we suggest a new grouping of ...
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Keywords {🔍}
macrophages, doi, cells, pubmed, google, scholar, macrophage, activated, immune, regulatory, production, activation, response, immunol, pmc, classically, monocytes, cytokines, populations, article, tissue, ifnγ, free, cell, population, receptor, host, woundhealing, blood, produce, inflammatory, responses, innate, produced, signals, proinflammatory, induced, intracellular, levels, physiology, function, expression, mice, development, monocyte, infection, induce, phenotype, alternatively, inflammation,
Topics {✒️}
granulocyte/macrophage colony-forming unit tissue-resident colony-forming cells macrophage colony-forming unit peroxisome proliferator-activated receptors membrane-spanning helical segments glucocorticoid-treated antigen-presenting cells macrophage colony-stimulating factor g-protein coupled receptor g-protein-coupled receptor pmc beta search membrane-bound apoptotic bodies mapk extracellular-signal-regulated kinase transforming growth factor-β bacterium francisella tularensis replenish tissue-macrophage numbers g-protein-coupled receptors hypothalamic–pituitary–adrenal axis /cbmg/faculty/mosser/mosserlab β-adrenoceptor-mediated mechanism mitogen-activated protein kinases inducible nitric-oxide synthase oxidized low-density lipoprotein confer bone-resorption properties de-activate neighbouring macrophages71 il-4-primed cells converts ifn-γ-mediated immunity inhibit t-cell proliferation replenish tissue-specific macrophages il-27 receptor α-chain homeostatic activities—host defence potent anti-inflammatory cytokine cell-mediated immune responses trimeric intracellular-signalling proteins macrophage surface-protein expression secrete pro-inflammatory cytokines th2-type immune responses poor antigen-presenting cells induce cytokine-gene transcription classically activated-macrophage phenotype lack chitin-degrading activity inhibit nitric-oxide production pro-inflammatory cytokine genes hypothalamic–pituitary–adrenal t-helper-17-cell responses atherosclerosis-prone blood vessels97 intracellular pattern-recognition receptors tlr4-mediated ifnγ production antigen-specific immune cells cell-mediated immune response tissue-resident macrophage populations
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